University of California - Davis Medical Center
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 35 Trials 
51 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Makkar, Raj
PORTICO IDE, NCT02000115: Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial

Recruiting
N/A
1150
US, RoW
Portico transcatheter aortic valve, Commercially available transcatheter aortic valve
Abbott Medical Devices
Aortic Valve Stenosis
10/19
07/25
NCT04338347: CAP-1002 in Severe COVID-19 Disease

No Longer Available
N/A
US
CAP-1002 Allogeneic Cardiosphere-Derived Cells
Capricor Inc.
COVID-19
 
 
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

Active, not recruiting
N/A
1948
Canada, US
ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL
Boston Scientific Corporation
Aortic Stenosis
06/24
09/34
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting
N/A
958
Canada, US
Tendyne Mitral Valve System, MitraClip System
Abbott Medical Devices
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
05/24
06/28
NCT05061004: Cephea Early Feasibility Study

Recruiting
N/A
50
Canada, US
Cephea Mitral Valve System
Abbott Medical Devices
Mitral Regurgitation
03/26
03/31
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
NCT04433065: TTVR Early Feasibility Study

Recruiting
N/A
15
US
Intrepid™ TTVR System
Medtronic Cardiovascular
Tricuspid Regurgitation
07/25
07/31
RESOLVE, NCT02318342: Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

Recruiting
N/A
3000
US
Warfarin, Coumadin
Cedars-Sinai Medical Center
Prosthetic Valve Thrombosis
12/25
12/26
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Recruiting
N/A
210
US
Transseptal ViMAC, ViMAC
Mayra Guerrero
Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease
12/24
12/24
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Recruiting
N/A
870
Canada, US
Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
12/27
12/31
ARTIST, NCT06608823: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

Not yet recruiting
N/A
1016
NA
Transcatheter Aortic Valve Replacement (TAVR) using Trilogy THV System, SAVR
JenaValve Technology, Inc.
Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency
02/26
02/36
CHOICE-MI, NCT04688190: CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

Recruiting
N/A
800
Europe, Canada, US, RoW
Universitätsklinikum Hamburg-Eppendorf, Montreal Heart Institute, University Hospital, Bordeaux
Mitral Regurgitation
03/25
12/30
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
BASELINE, NCT04843072: Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis

Recruiting
N/A
400
Europe, Canada, US
Evolut R/PRO bioprosthesis, Edwards Sapien S3/Ultra bioprosthesis
Erasmus Medical Center
Valve Heart Disease
05/26
05/26
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
NCT05427370: The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Recruiting
N/A
754
Europe, Canada, US, RoW
Revascularization by PCI, Revascularization by CABG
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR), Weill Medical College of Cornell University
Coronary Artery Disease, Heart Failure Systolic
04/29
12/29
PROGRESS, NCT04889872: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

Recruiting
N/A
2250
Europe, Canada, Japan, US, RoW
SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA
Edwards Lifesciences
Aortic Stenosis, Calcific, Aortic Valve Stenosis
06/29
06/37
NCT00573027: Heart Disease of the Small Arteries in Women and Men

Recruiting
N/A
634
US
noninvasive tests
Cedars-Sinai Medical Center
Heart Disease
01/40
01/40
Rogers, Jason
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting
N/A
958
Canada, US
Tendyne Mitral Valve System, MitraClip System
Abbott Medical Devices
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
05/24
06/28
NCT05061004: Cephea Early Feasibility Study

Recruiting
N/A
50
Canada, US
Cephea Mitral Valve System
Abbott Medical Devices
Mitral Regurgitation
03/26
03/31
FPP, NCT06672874: Fermented Papaya and Driving Simulator Older Adult Study

Not yet recruiting
N/A
30
US
Fermented Papaya Preparation (FPP)
University of Florida, Osato Research Institute
Healthy
03/26
05/26
Price, Matthew J
LEMURS-P, NCT05841979: The Lived Experiences Measured Using Rings Pilot Study

Active, not recruiting
2
600
US
Moodlifters, Physical Activity, Nature Experiences
University of Vermont, MassMutual - Private Industry Funded
Depression, Stress, Sleep, Anxiety
12/24
05/27
LEMURSSI, NCT06340841: LEMURS SSI: Evaluation of Behavioral Incentives

Recruiting
1
200
US
Personal Incentives, Personal Restorative Incentives, Charity Incentives, Charity Restorative Incentives
University of Vermont
Incentives
05/24
05/28
Rebalance-HF, NCT04592445: Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

Recruiting
N/A
80
US
Satera GSN Ablation, Sham Control
Axon Therapies, Inc.
Heart Failure With Preserved Ejection Fraction
04/22
03/23
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
TRICAV, NCT06137807: TRIcvalve BiCAVal Valve System for Severe Tricuspid Regurgitation (-I)

Recruiting
N/A
15
US
TricValve® Transcatheter Bicaval Valve System, TricValve System
P+F Products + Features USA Inc., P+F Products + Features GmbH, Meditrial USA Inc.
Tricuspid Regurgitation, Tricuspid Valve Disease
11/25
09/29
NCT05966662: Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)

Active, not recruiting
N/A
145
US
IVL with Shockwave C2+ 2Hz Coronary IVL Catheter
Shockwave Medical, Inc.
Coronary Artery Disease, Myocardial Infarction
01/25
12/25
CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
REDUCE PAS, NCT03821129: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

Recruiting
N/A
636
US
PFO closure with GORE® CARDIOFORM Septal Occluder
W.L.Gore & Associates
Stroke, PFO - Patent Foramen Ovale
12/26
12/29
Ali, Ziad
NCT03507777: ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)

Completed
N/A
2487
Europe, Canada, Japan, US, RoW
Coronary PCI guided by OCT, Optical Coherence Tomography, Coronary PCI guided by Angiography
Abbott Medical Devices, Abbott
Coronary Artery Disease, Coronary Stenosis, Atherosclerosis, STEMI, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
02/23
02/23
PROGRESS CTO, NCT02061436: Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

Recruiting
N/A
2000
Europe, Canada, US, RoW
Minneapolis Heart Institute Foundation
Coronary Artery Disease
01/24
01/24
NCT06018194: ELUCIDATE FFRct Study

Recruiting
N/A
350
US
ElucidVivo
Elucid Bioimaging Inc., Lundquist Institute at Harbor-UCLA Medical Center
Coronary Artery Disease
07/24
07/24
OPTOCAB, NCT05129228: Optical Coherence Tomography of the Saphenous Vein Graft

Recruiting
N/A
760
US
OCT-guided saphenous vein CABG, ILUMIEN OPTIS NEXT OCT Imaging System, ILUMIEN OPTIS OCT Imaging System, OPTIS Integrated OCT Imaging System, OPTIS Mobile OCT Imaging System, Dragonfly Duo Catheter, Dragonfly OPTIS Catheter, Dragonfly OpStar Imaging Catheter, Dual Channel AureFlo Systems, Coronary Flowprobes
St. Francis Hospital, New York
Coronary Bypass Graft Stenosis
04/24
04/26
NCT03786614: Antidepressant Discontinuation in Treatment Resistant Depression

Recruiting
N/A
30
US
Discontinuation of serotonergic antidepressants, Continuation of serotonergic medications
University of Louisville
Treatment Resistant Depression
12/24
12/24
SPIRIT XLV PAS, NCT05423379: XIENCE Skypoint Large Vessel Post Approval Study

Active, not recruiting
N/A
102
Europe, US
XIENCE Skypoint Large Vessel Everolimus Eluting Coronary Stent System (EECSS)
Abbott Medical Devices
Coronary Artery Disease
08/25
08/27
Allen, Roblee
PHAR, NCT04071327: Pulmonary Hypertension Association Registry

Recruiting
N/A
3000
US
Pulmonary Hypertension Association, Inc., University of Washington, the Collaborative Health Studies Coordinating Center
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
10/25
10/25
Book, Kimberly
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
Book, Kimberley
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting
N/A
958
Canada, US
Tendyne Mitral Valve System, MitraClip System
Abbott Medical Devices
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
05/24
06/28
Singh, Gagan
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
NCT05565599: An Early Feasibility Study Evaluating the Safety and Efficacy of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation

Active, not recruiting
N/A
45
US
Left Atrial Appendage Closure
Laminar, Inc.
Non-valvular Atrial Fibrillation
08/24
09/29
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Tuermer-Lee, Kaelyn
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Recruiting
N/A
958
Canada, US
Tendyne Mitral Valve System, MitraClip System
Abbott Medical Devices
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
05/24
06/28
NCT05061004: Cephea Early Feasibility Study

Recruiting
N/A
50
Canada, US
Cephea Mitral Valve System
Abbott Medical Devices
Mitral Regurgitation
03/26
03/31
Chernyetsky, Carolina
NCT05061004: Cephea Early Feasibility Study

Recruiting
N/A
50
Canada, US
Cephea Mitral Valve System
Abbott Medical Devices
Mitral Regurgitation
03/26
03/31

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