University Hospitals, Cleveland Medical Center
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 37 Trials 
72 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
McCandless, Shawn
VNS4PWS, NCT06144645: A Clinical Evaluation of Non-Invasive Vagus Nerve Stimulation for Temper Outbursts in People with PWS

Recruiting
3
102
US
tVNS, intermittent stimulation, tVNS R, manufactured by tVNS Technologies, intermittent stimulation, tVNS, continuous stimulation, tVNS R, manufactured by tVNS Technologies, continuous stimulation
Foundation for Prader-Willi Research, RTI International
Prader-Willi Syndrome
12/26
12/27
NCT06366464: A Study of Pitolisant in Patients with Prader-Willi Syndrome

Recruiting
3
134
US
Pitolisant tablet, pitolisant, Placebo tablet, placebo
Harmony Biosciences, LLC
Prader-Willi Syndrome
07/26
07/27
NCT05153434: A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome

Active, not recruiting
2
18
US
ARD-101
Aardvark Therapeutics, Inc., Children's Hospital Colorado, Stanford University
Prader-Willi Syndrome
11/24
02/25
NCT04612764: Liver Disease in Urea Cycle Disorders

Recruiting
N/A
62
US
Baylor College of Medicine, Children's National Research Institute, Seattle Children's Hospital, Children's Hospital Colorado, Children's Hospital of Philadelphia
Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency, Citrullinemia 1, ARGI Deficiency, ASL Deficiency, Argininosuccinic Aciduria, ASS Deficiency, Hyperargininemia
12/24
12/24
NCT00237315: Longitudinal Study of Urea Cycle Disorders

Recruiting
N/A
1500
Europe, Canada, US
Andrea Gropman, National Center for Research Resources (NCRR), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Rare Diseases Clinical Research Network
Brain Diseases, Metabolic, Inborn, Amino Acid Metabolism, Inborn Errors, Urea Cycle Disorders
07/25
07/26
Hayek, Salim
SERENITY CM, NCT05614648: Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet

Terminated
3
17
US
Clonidine Micropellets, Tuohy epidural needle
Sollis Therapeutics, Inc.
Lumbosacral Radiculopathy
03/24
03/24
ATRIUM, NCT05335928: Abatacept in Immune Checkpoint Inhibitor Myocarditis

Recruiting
3
390
Canada, US
Abatacept plus, Orencia, Placebo
Massachusetts General Hospital, Bristol-Myers Squibb
Myocarditis Acute, Cancer
11/26
04/27
NCT05815485: A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Determine the Safety and Effectiveness of Azeliragon in the Treatment of Patients Hospitalized for Coronavirus Disease 2019 (COVID-19) or Pneumonia

Recruiting
2/3
144
US
Azeliragon, Placebo
Salim S. Hayek
COVID-19
04/26
04/26
NCT05469074: Noninvasive Brain Stimulation for Diabetic Neuropathic Pain

Recruiting
2
80
US
Active tDCS + Active TUS, Device: Sham
Case Western Reserve University, Highland Instruments, Inc.
Diabetic Neuropathies, Chronic Pain
08/23
08/24
ISIC, NCT04818866: International Study of Inflammation in COVID-19

Completed
N/A
4463
US
SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase
University of Michigan, Rush University, Copenhagen University Hospital, Hvidovre, University of Athens, Heinrich-Heine University, Duesseldorf, University of Thessaly, Charite University, Berlin, Germany
Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury, Inflammation
12/22
12/22
M2C2, NCT04706533: Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19

Completed
N/A
3402
US
Biomarkers of inflammation
University of Michigan
Covid19, Kidney Diseases, Inflammation, SARS-CoV Infection
12/22
12/22
NCT05469438: IMAS Optimization and Applicability in an Acute Stroke Setting.

Active, not recruiting
N/A
30
US
Case Western Reserve University, Highland Instruments, Inc.
Acute Stroke
08/23
09/25
KIDCOV, NCT04705766: KIDney Injury in Times of COVID-19

Recruiting
N/A
2000
US
Urine Collection
University of California, San Francisco, Rush University Medical Center, University of Michigan, University of California
SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury, Kidney Injury
03/26
03/26
NCT03625752: Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain

Recruiting
N/A
60
US
Active Comparator: Active tDCS + Active TUS, Sham
Case Western Reserve University, Highland Instruments, Inc.
Diabetic Neuropathies, Chronic Pain
12/24
05/25
NCT05811143: Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

Completed
N/A
3
US
Spinal Cord Stimulator
University Hospitals Cleveland Medical Center
Lipomatosis, Low Back Pain
01/24
01/24
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Active, not recruiting
N/A
203
US
ReActiv8
Mainstay Medical
Chronic Low-back Pain
09/24
01/26
NCT05945121: Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Recruiting
N/A
10
US
Cardio-oncology program
University of Michigan Rogel Cancer Center, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Hematopoietic Stem Cell Transplant
08/27
08/27
Cho, Jae Yong
INTEGRATEIIb, NCT04879368 / 2020-004617-12: RegoNivo vs Standard of Care Chemotherapy in AGOC

Active, not recruiting
3
450
Europe, Japan, US, RoW
Regorafenib, Stivarga, Nivolumab, Opdivo, Docetaxel, Taxotere, Paclitaxel, Abraxane, Irinotecan, Camptosar, Trifluridine/Tipracil, Lonsurf
Australasian Gastro-Intestinal Trials Group, Bayer, Bristol-Myers Squibb, University of Sydney, Academic and Community Cancer Research United, Taiwanese Cooperative Oncology Group, Frankfurter Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, National Cancer Center Hospital East, Syneos Health
Gastro-Oesophageal Cancer
06/25
06/26
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
SGNLVA-005, NCT04032704 / 2019-001946-17: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors

Terminated
2
205
Europe, US, RoW
ladiratuzumab vedotin, SGN-LIV1A, pembrolizumab, Keytruda
Seagen Inc., Merck Sharp & Dohme LLC
Small Cell Lung Cancer, Non-small Cell Lung Cancer, Squamous, Non-small Cell Lung Cancer, Non-squamous, Head and Neck Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Prostate Cancer, Melanoma
11/23
11/23
BA3011-001, NCT03425279: CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients with Sarcoma

Active, not recruiting
1/2
300
US, RoW
CAB-AXL-ADC, PD-1 inhibitor
BioAtla, Inc.
Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma
01/25
01/25
VISION, NCT04151615: VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma

Completed
N/A
203
RoW
Boryung Pharmaceutical Co., Ltd
Multiple Myeloma
01/23
01/23
TRIOMPHE, NCT04471909: NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

Recruiting
N/A
110
US, RoW
NEXUS Aortic Stent Graft System
Endospan Ltd.
Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
11/24
10/29
NCT05053295: Investigator-initiated Pilot Study to Investigate the Efficacy and Safety of Immuncell-LC in Combination With Nivolumab (Opdivo) in Subjects With Advanced or Recurrent Gastric Cancer

Recruiting
N/A
20
RoW
autologous activated T lymphocyte, Immuncell-LC (Autologous activated T lymphocyte),
Gangnam Severance Hospital
Relapsed or Advanced Gastric Adenocarcinoma, Gastro-esophageal Junction Cancer
07/23
09/23
ADVANCE, NCT05378347: Endurant Stent Graft System vs Excluder Endoprothesis: Trial

Recruiting
N/A
550
Europe, Japan, US, RoW
Medtronic Endurant II or Endurant IIs Stent Graft System, Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
Medtronic Cardiovascular
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
05/27
05/31
PANTHER, NCT04545502: Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

Recruiting
N/A
2000
Europe, Canada, US
Gelsoft Plus Vascular Graft, Gelsoft Plus, Vascular Bypass Graft, Gelsoft Plus Extra Anatomical, Cardiovascular Patch, Gelseal Patch, Gelsoft Patch, Thinwall Patch, Cardiovascular Fabrics, Gelweave Vascular Graft, Gelweave, Gelweave Valsalva Vascular Graft, Gelweave Valsalva
Vascutek Ltd.
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
01/26
01/33
ASSIST, NCT05529459: Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD

Recruiting
N/A
2400
RoW
Percutaneous Coronary Intervention
Seung-Whan Lee, M.D., Ph.D., Biotronik Korea Co., Ltd
Coronary Disease
12/26
07/30
Mahipal, Amit
FIRST-308, NCT05948475: Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma

Recruiting
3
200
Europe, US, RoW
Tinengotinib 8 mg, Tinengotinib 10 mg, Physician's Choice
TransThera Sciences (Nanjing), Inc.
Cholangiocarcinoma
05/26
08/26
NCT03278106: TAS-102 in Treating Advanced Biliary Tract Cancers

Completed
2
28
US
Laboratory Biomarker Analysis, Trifluridine/Tipiracil Hydrochloride Combination Agent TAS-102, Lonsurf, TAS-102, Trifluridine/Tipiracil
Mayo Clinic, National Cancer Institute (NCI)
Cholangiocarcinoma, Stage III Gallbladder Cancer AJCC v7, Stage IIIA Gallbladder Cancer AJCC v7, Stage IIIB Gallbladder Cancer AJCC v7, Stage IV Gallbladder Cancer AJCC v7, Stage IVA Gallbladder Cancer AJCC v7, Stage IVB Gallbladder Cancer AJCC v7
11/18
09/21
NCT04072445: Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Completed
2
28
US
Irinotecan, Irinotecan Hydrochloride, Campto, Camptosar, Camptothecin 11, Camptothecin-11, CPT 11, CPT-11, Irinomedac, Irinotecan Hydrochloride Trihydrate, Irinotecan Monohydrochloride Trihydrate, U-101440E, Trifluridine and Tipiracil Hydrochloride, Lonsurf, TAS 102, TAS-102, Tipiracil Hydrochloride Mixture with Trifluridine, Trifluridine/Tipiracil, Trifluridine/Tipiracil Hydrochloride Combination Agent TAS-102
Mayo Clinic, National Comprehensive Cancer Network
Advanced Bile Duct Carcinoma, Advanced Gallbladder Carcinoma, Refractory Bile Duct Carcinoma, Refractory Gallbladder Carcinoma, Stage III Distal Bile Duct Cancer AJCC v8, Stage III Gallbladder Cancer AJCC v8, Stage III Intrahepatic Bile Duct Cancer AJCC v8, Stage IIIA Distal Bile Duct Cancer AJCC v8, Stage IIIA Gallbladder Cancer AJCC v8, Stage IIIA Intrahepatic Bile Duct Cancer AJCC v8, Stage IIIB Distal Bile Duct Cancer AJCC v8, Stage IIIB Gallbladder Cancer AJCC v8, Stage IIIB Intrahepatic Bile Duct Cancer AJCC v8, Stage IV Distal Bile Duct Cancer AJCC v8, Stage IV Gallbladder Cancer AJCC v8, Stage IV Intrahepatic Bile Duct Cancer AJCC v8, Stage IVA Gallbladder Cancer AJCC v8, Stage IVB Gallbladder Cancer AJCC v8
08/21
08/21
SURPASS-2, NCT04752358 / 2020-005802-24: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers

Terminated
2
3
Europe, Canada, US
Autologous genetically modified ADP-A2M4CD8 cells
Adaptimmune, ICON plc
Esophageal Cancer, Esophagogastric Junction Cancer
06/23
12/23
NCT04919642: Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma

Completed
2
55
US
TT-00420
TransThera Sciences (Nanjing), Inc.
Cholangiocarcinoma, FGFR2 Fusion, FGFR2 Gene Mutation, FGFR1 Alteration, FGFR3 Alteration
02/24
02/24
NCT04042831: Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Recruiting
2
36
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Olaparib, AZD 2281, AZD-2281, AZD2281, KU-0059436, Lynparza, PARP Inhibitor AZD2281
Academic and Community Cancer Research United, National Cancer Institute (NCI)
Bile Duct Adenocarcinoma, Fanconi Anemia Complementation Group Gene Mutation, Metastatic Bile Duct Carcinoma, PTEN Gene Deletion
08/24
03/25
ACCRU-GI-2008, NCT05168163: Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Recruiting
2
122
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG7446, RO5541267, Tecentriq, Cabozantinib, Lenvatinib, E7080, ER-203492-00, Multi-Kinase Inhibitor E7080
Academic and Community Cancer Research United, National Cancer Institute (NCI), Genentech, Inc.
Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IVA Hepatocellular Carcinoma AJCC v8, Stage IVB Hepatocellular Carcinoma AJCC v8, Unresectable Hepatocellular Carcinoma
12/24
12/26
ELU-FRα-1, NCT05001282: A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)

Terminated
1/2
79
US
ELU001, FA-CDC
Elucida Oncology
Ovarian Cancer, Ovarian Neoplasms, Ovarian Carcinoma, Endometrial Cancer, Ovary Cancer, Ovary Neoplasm, Ovary Disease, Ovary Metastasis, Ovarian Diseases, Ovarian Cancer Stage, Ovarian Epithelial Cancer, Ovarian Adenocarcinoma, Ovarian Serous Adenocarcinoma, Ovarian Neoplasm Epithelial, Ovarian Cancer Recurrent, Endometrial Diseases, Endometrial Adenocarcinoma, Endometrial Carcinosarcoma, Endometrial Clear Cell Adenocarcinoma, Endometrioid Adenocarcinoma, Endometrial Neoplasms, Endometrial Cancer Recurrent, Endometrioid Tumor, Fallopian Tube Cancer, Peritoneal Cancer
06/24
06/24
ABOYA-119, NCT04905914: Study of ATRN-119 in Patients with Advanced Solid Tumors

Recruiting
1/2
132
US
ATRN-119
Aprea Therapeutics
Advanced Solid Tumor
12/24
06/25
XTX301-01, NCT05684965: XTX301 in Patients with Advanced Solid Tumors

Recruiting
1/2
358
US
XTX301
Xilio Development, Inc.
Advanced Solid Tumor
02/27
02/27
PCS6422-GI-01, NCT04861987: A Study of the Safety and PK of PCS6422 (Eniluracil) with Capecitabine in Patients with Advanced, Refractory GI Tract Tumors

Completed
1
23
US
PCS6422 and capecitabine
Processa Pharmaceuticals
Advanced Cancer, Refractory Cancer, Tumor Gastric
06/24
09/24
NCT04088188: Gemcitabine and Cisplatin With Ivosidenib or Pemigatinib for the Treatment of Unresectable or Metastatic Cholangiocarcinoma

Terminated
1
8
US
Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone''s Chloride, Peyrone''s Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Ivosidenib, AG-120, Tibsovo, Pemigatinib, INCB054828, Pemazyre
Academic and Community Cancer Research United, National Cancer Institute (NCI)
Advanced Cholangiocarcinoma, Metastatic Cholangiocarcinoma, Unresectable Cholangiocarcinoma
12/23
12/23
KZR-261-101, NCT05047536: KZR-261 in Subjects With Advanced Solid Malignancies

Active, not recruiting
1
61
US
KZR-261, KZR-261 for Injection
Kezar Life Sciences, Inc.
Advanced/Metastatic Solid Tumor
12/25
12/26
KISIMA-02, NCT05846516: A Study to Evaluate ATP150/ATP152, VSV-GP154 and Ezabenlimab in Patients With KRAS G12D/G12V Mutated PDAC

Recruiting
1
85
Europe, US
VSV-GP154, ATP150, ATP152, Ezabenlimab
Amal Therapeutics, Boehringer Ingelheim
Pancreatic Ductal Adenocarcinoma
12/26
03/27
Shishehbor, Mehdi
R2P Registry, NCT04371861: Observational Study to Assess Transradial Access for Treatment in the Lower Extremities.

Completed
N/A
120
US
Peripheral Artery Treatment
Terumo Medical Corporation
Peripheral Arterial Disease
08/21
06/22
NCT03970538: PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Active, not recruiting
N/A
105
US
LimFlow System
LimFlow, Inc.
Critical Limb Ischemia, Critical Lower Limb Ischemia, Peripheral Artery Disease, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Arterial Occlusive Diseases, Arterial Occlusion, Arterial Disease, Peripheral Artery Occlusion, Peripheral Vascular Disease, Peripheral Ischemia, Vascular Diseases
09/22
02/25
iVEST, NCT04748965: Imaging-Guided Vessel Sizing in the Tibial Arteries

Completed
N/A
40
US
Digital Subtraction Angiography
University Hospitals Cleveland Medical Center, Abbott Medical Devices
Peripheral Artery Disease, Critical Limb Ischemia
06/24
06/24
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Recruiting
N/A
1400
Europe, US, RoW
Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation
Medtronic Vascular
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
11/26
11/29
JETi, NCT04370691: Peripheral Thrombectomy Registry

Active, not recruiting
N/A
260
Europe, Canada, US, RoW
JETi Peripheral Thrombectomy System
Abbott Medical Devices
Peripheral Artery Thrombosis, Peripheral Venous Thrombosis
08/24
08/25
TIC, NCT06544135: Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

Not yet recruiting
N/A
25
US
FLIR One Pro LT
University Hospitals Cleveland Medical Center
Peripheral Arterial Disease, Critical Limb Ischemia, Critical Lower Limb Ischemia
10/27
10/27
NCT02924857: The Chocolate Touch Study

Active, not recruiting
N/A
333
Europe, US, RoW
Chocolate Touch, Chocolate Touch™ Paclitaxel Coated Balloon Catheter, Lutonix Drug Coated Balloon, LUTONIX® 035 Drug Coated Balloon Catheter
TriReme Medical, LLC
Peripheral Artery Disease (PAD), Ischemia, Intermittent Claudication
06/25
12/26
NCT05313165: PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Recruiting
N/A
100
US
LimFlow Stent Graft System
LimFlow, Inc.
Critical Limb Ischemia, Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease
05/27
05/27
XLPAD, NCT01904851: Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

Recruiting
N/A
14000
US
Baylor Research Institute, Boston Scientific Corporation
Peripheral Arterial Disease
01/33
01/33
Margiotti, Regina
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Recruiting
3
5350
US
AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI)
Atrial Fibrillation
07/29
07/29
COMPETENCE, NCT01187368: Prospective Multi-Center Randomized Study for Evaluating the EVAHEART®2 Left Ventricular Assist System

Suspended
N/A
399
US
EVAHEART Left Ventricular Assist System (LVAS), EVA2, HeartMate 3, HM3
Evaheart, Inc.
Heart Failure
07/27
07/28
NCT03523416: Early Feasibility Study - Edwards APTURE Transcatheter Shunt System

Active, not recruiting
N/A
71
US
Transcatheter Atrial Shunt System
Edwards Lifesciences
Heart Failure
12/23
11/28
Parks, Traci
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28
Pelletier, Marc
NCT05545930: Analysis of Red Blood Cell Integrity and Efficiency of Recovery Using a Novel Surgical Sponge-Blood Recovery Device (ProCell): Immediate Impact

Recruiting
N/A
12
US
Hand Wrung, ProCell Wrung
Marc Pelletier, ProCell Surgical Inc.
Blood Recovery
02/25
02/25
STAR-T, NCT04976530: Safe and Timely Antithrombotic Removal - Ticagrelor

Completed
N/A
140
Canada, US
DrugSorb-ATR system, Sorbent hemoperfusion system, Sham comparator
CytoSorbents, Inc
Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
08/23
08/23
NCT05545956: Analysis of Red Blood Cell Integrity and Efficiency of Recovery Using a Novel Surgical Sponge-Blood Recovery Device (ProCell): Delayed Impact

Withdrawn
N/A
22
US
Hand Wrung, ProCell Wrung
University Hospitals Cleveland Medical Center, ProCell Surgical Inc.
Blood Recovery
01/25
01/25
NCT06660186: Sternal Plating High Risk

Not yet recruiting
N/A
250
US
Rigid Sternal Fixation, Wire Cerclage
Marc Pelletier, Stryker Nordic
Heart Diseases
06/27
06/27
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Mazzurco, Stacey
stAAAble, NCT06001918: Nectero EAST System Clinical Study

Recruiting
2/3
400
US
Nectero EAST System
Nectero Medical, Inc.
Abdominal Aortic Aneurysm
03/27
12/29
STAR-T, NCT04976530: Safe and Timely Antithrombotic Removal - Ticagrelor

Completed
N/A
140
Canada, US
DrugSorb-ATR system, Sorbent hemoperfusion system, Sham comparator
CytoSorbents, Inc
Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
08/23
08/23
NCT06660186: Sternal Plating High Risk

Not yet recruiting
N/A
250
US
Rigid Sternal Fixation, Wire Cerclage
Marc Pelletier, Stryker Nordic
Heart Diseases
06/27
06/27
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
LeAAPS, NCT05478304: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

Recruiting
N/A
6500
Europe, Canada, US
AtriClip LAA Exclusion System
AtriCure, Inc., Population Health Research Institute
Ischemic Stroke, Systemic Embolism
12/31
04/32
Becerra, Mario A
NCT05469438: IMAS Optimization and Applicability in an Acute Stroke Setting.

Active, not recruiting
N/A
30
US
Case Western Reserve University, Highland Instruments, Inc.
Acute Stroke
08/23
09/25
NCT05811143: Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

Completed
N/A
3
US
Spinal Cord Stimulator
University Hospitals Cleveland Medical Center
Lipomatosis, Low Back Pain
01/24
01/24
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Active, not recruiting
N/A
203
US
ReActiv8
Mainstay Medical
Chronic Low-back Pain
09/24
01/26
Mullenax, Emily
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Recruiting
N/A
1400
Europe, US, RoW
Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation
Medtronic Vascular
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
11/26
11/29
NCT04943172: The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study

Recruiting
N/A
75
US
Hancock-Jaffe bioprosthetic venous valve (VenoValve®)
Hancock Jaffe Laboratiores, Inc, AXIOM Real Time Metrics, Syntactx
Deep Venous Insufficiency (Diagnosis)
03/24
03/28
ElAmm, Chantal
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28

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