Translational Research Institute for Metabolism and Diabetes
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 66 Trials 
18 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Mayer-Davis, Elizabeth
NCT05701657: Nutrition for Precision Health, Powered by the All of Us

Recruiting
N/A
8000
US
Diet A, Diet B, Diet C, Liquid Mixed Meal Tolerance Test, LMMTT, Diet-Specific Mixed Meal Tolerance Test, Diet-Specific MMTT
RTI International, National Institutes of Health (NIH), University of North Carolina, Chapel Hill, Northwestern University, Illinois Institute of Technology, University of Chicago, Pennington Biomedical Research Center, Louisiana State University Health Sciences Center in New Orleans, University of California, Davis, University of California, Los Angeles, Cedars-Sinai Medical Center, University of Alabama at Birmingham, Tufts University, Massachusetts General Hospital, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Center for Advancing Translational Sciences (NCATS), National Cancer Institute (NCI), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), City University of New York, School of Public Health, Mayo Clinic, University of California, San Diego, University of Hawaii, Vanderbilt University Medical Center, National Heart, Lung, and Blood Institute (NHLBI), National Center for Complementary and Integrative Health (NCCIH), National Institute of Drug Abuse, Public Health Informatics Computational and Operations Research, University of Southern California, Cornell University, University of Alabama, Tuscaloosa, North Carolina State University, University of North Carolina, Charlotte, Duke University, Stevens Institute of Technology, Purdue University, United States Military Academy at West Point, USDA, Western Human Nutrition Research Center, North Carolina Central University, Wake Forest University Health Sciences, Boston University, Children's Hospital of Richmond, Virginia Commonwealth University, Verily Life Sciences LLC, Indiana University, Fred Hutchinson Cancer Center, Columbia University, University of Pennsylvania
Nutrition, Health, Dietary Habits
12/26
01/27
Smith, Steven R
NCT05026866: A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)

Active, not recruiting
3
2196
Japan, US
Donanemab, LY3002813, Placebo
Eli Lilly and Company
Alzheimer Disease
11/27
11/27
NCT06313528: A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943

Recruiting
1
74
US
LY3437943, Placebo
Eli Lilly and Company
Obesity
10/25
10/25
Columbus, NCT01911091: Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation

Active, not recruiting
N/A
56
US
Exercise
AdventHealth Translational Research Institute, Sanford-Burnham Medical Research Institute, Takeda
Obesity, Disorder of Lipid Storage and Metabolism, Lipid Metabolism Disorders, Metabolic Disorder
12/14
12/24
Maahs, David M
INHALE-1, NCT04974528: Afrezza® Study in Pediatrics

Active, not recruiting
3
319
US
Afrezza, Technosphere Insulin, Rapid-acting Insulin Analog, insulin aspart, insulin lispro, insulin glulisine, Novolog®, Fiasp®, Humalog®, Admelog®, Apidra®, Basal Insulin, insulin glargine, insulin degludec, insulin detemir, Lantus®, Abasaglar®, Basaglar®, Semglee®, Toujeo®, Tresiba®, Levemir®
Mannkind Corporation, Jaeb Center for Health Research
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
10/24
05/25
SUGARNSALT, NCT06217302: Sotagliflozin to Slow Kidney Function Decline in Persons with Type 1 Diabetes and Diabetic Kidney Disease

Recruiting
3
150
Canada, US
Sotagliflozin, INPEFA, Placebo
Alessandro Doria, Canadian Institutes of Health Research (CIHR), The Kidney Foundation of Canada, The Cleveland Clinic, University of Michigan, University of Colorado, Denver, Northwestern University, Washington University School of Medicine, State University of New York - Upstate Medical University, Providence Medical Research Center, Stanford University, Montefiore Medical Center, University of Toronto, University Health Network, Toronto, University of Calgary, University of Alberta, University of British Columbia, Institut de Recherches Cliniques de Montreal, LMC Diabetes & Endocrinology Ltd., Joslin Diabetes Center, Lexicon Pharmaceuticals, DexCom, Inc., University of Washington, Breakthrough T1D
Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
12/28
05/29
NCT04839575: Study of Latiglutenase in T1D/CD Patients

Terminated
2
13
US
Latiglutenase, IMGX003, Placebo
Entero Therapeutics, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Immunogenics, LLC
Celiac Disease
12/22
12/22
Pratley, Richard E
NCT04628481 / 2020-001926-71: A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Active, not recruiting
2
140
Europe, US, RoW
Ladarixin, allosteric inhibitor of CXCL8 (IL-8), CXCR1 and CXCR2 receptors, Placebo
Dompé Farmaceutici S.p.A, Dompe farmaceutici s.p.a.
Recent Onset type1 Diabetes
04/24
04/26
Goodpaster, Bret H
ABA, NCT04722354: Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity

Active, not recruiting
2
48
US
Hyperinsulemic euglycemic clamp, Muscle Biopsy, Oral abscisic acid (ABA), Placebo
AdventHealth Translational Research Institute, BioTherapeutics Inc.
Pre Diabetes
12/24
12/24
NCT02238600: Evaluation of a Complete Oral Nutritional Supplement on Lean Body Mass in Healthy Older Subjects During Bed Rest and Recovery

Recruiting
1
30
US
Oral Nutritional Supplement
Translational Research Institute for Metabolism and Diabetes, Florida, Abbott Nutrition
Sarcopenia
09/15
 
Corbin, Karen
AVAIL, NCT04807868: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry

Recruiting
N/A
1250
US
Standard of care liver biopsy, Fibroscan, Biospecimen Collection
AdventHealth Translational Research Institute, Berg, LLC
Non-Alcoholic Fatty Liver Disease
12/24
03/26
Martinez, Celines
NCT02238600: Evaluation of a Complete Oral Nutritional Supplement on Lean Body Mass in Healthy Older Subjects During Bed Rest and Recovery

Recruiting
1
30
US
Oral Nutritional Supplement
Translational Research Institute for Metabolism and Diabetes, Florida, Abbott Nutrition
Sarcopenia
09/15
 
Manager, Recruitment
NCT05644093: IM and IV SPL026 Drug Product in Healthy Participants

Completed
1
14
Europe
SPL026 IV, DMT, SPL026 IM
Small Pharma Ltd
Major Depressive Disorder
04/23
04/23
NCT06127199: Contraceptive Efficacy Study of Ovaprene

Recruiting
N/A
656
US
Ovaprene
Daré Bioscience, Inc., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Contraception
06/25
09/25
Department, Recruitment
ABA, NCT04722354: Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity

Active, not recruiting
2
48
US
Hyperinsulemic euglycemic clamp, Muscle Biopsy, Oral abscisic acid (ABA), Placebo
AdventHealth Translational Research Institute, BioTherapeutics Inc.
Pre Diabetes
12/24
12/24
NCT05881993: Study of CBP-4888 in Healthy, Non-Pregnant Female Subjects

Recruiting
1
15
US
CBP-4888, Placebo
Comanche Biopharma
Healthy Volunteer Study
03/24
04/24
NCT06669091: Food-effect Study of Ecopipam Pharmacokinetics

Completed
1
25
US
Ecopipam tablet
Emalex Biosciences Inc.
Food-effect
12/24
12/24
AVAIL, NCT04807868: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry

Recruiting
N/A
1250
US
Standard of care liver biopsy, Fibroscan, Biospecimen Collection
AdventHealth Translational Research Institute, Berg, LLC
Non-Alcoholic Fatty Liver Disease
12/24
03/26

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