University of Manitoba - Health Sciences Centre
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 15 Trials 
21 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Connolly, Stuart
ARTESiA, NCT01938248 / 2014-001397-33: Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

Completed
4
4012
Europe, Canada, US, RoW
Apixaban, Eliquis, aspirin, ASA, acetylsalicylic acid
Population Health Research Institute, Bristol-Myers Squibb, Pfizer, Medtronic, Canadian Institutes of Health Research (CIHR)
Atrial Fibrillation, Stroke
10/23
11/23
TaRGET, NCT06174220: Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy

Not yet recruiting
2
120
Canada
Tideglusib, Placebo
Hamilton Health Sciences Corporation, Population Health Research Institute, Canadian Institutes of Health Research (CIHR), AMO Pharma, Hearts in Rhythm Organization (HiRO), Canadian SADS
Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy
02/26
07/26
STRATUS, NCT03578419: Small-Volume Tubes to Reduce Anemia and Transfusion

Completed
N/A
27411
Canada
Small-Volume Blood Collection Tubes, Standard-Volume Blood Collection Tubes
Population Health Research Institute
Blood Loss Anemia
01/21
06/24
PROTECT-HF, NCT03541616: Prevalence of Subclinical Atrial Fibrillation in Heart Failure Patients and Its Relationship With Hospital Readmission

Completed
N/A
242
Canada
ECG Patch, pocket ECG monitor
Population Health Research Institute, Heart and Stroke Foundation of Canada, Canadian Cardiovascular Society
Heart Failure, Atrial Fibrillation
01/22
03/23
B-Free, NCT03928236: Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium

Active, not recruiting
N/A
15886
Canada, US
Limited Intraoperative Benzodiazepine, Liberal Intraoperative Benzodiazepine
Population Health Research Institute
Delirium, Post-cardiac Surgery
12/22
11/24
INTERCEPT, NCT05723926: Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

Not yet recruiting
N/A
2000
NA
Vine Filter, Vine Embolic Protection System
Javelin Medical, Population Health Research Institute
Atrial Fibrillation, Oral Anticoagulation, Stroke, Implant
12/28
10/30
Bernstein, Charles N
ABX464-106, NCT05507216: ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

Recruiting
3
612
Europe, Canada, Japan, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
03/25
04/25
ABTECT, NCT05535946: - Maintenance

Recruiting
3
1050
Europe, Canada, Japan, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
01/26
01/30
IBDDysplasia, NCT04067778: IBD Neoplasia Surveillance Pilot RCT

Completed
N/A
600
Canada
Intervention Group, Control Group
Ottawa Hospital Research Institute, Health Sciences Centre, Winnipeg, Manitoba, Western University, Canada, University of Toronto, Hamilton Health Sciences Corporation, Thunder Bay Regional Health Sciences Centre, Eastern Health, McGill University Health Centre/Research Institute of the McGill University Health Centre, Providence Health & Services, Royal Jubilee Hospital, University of Alberta, MOUNT SINAI HOSPITAL, Nova Scotia Health Authority
Inflammatory Bowel Diseases, Colonic Neoplasms, Dysplasia
09/22
10/22
NCT05809999: IBD Neoplasia Surveillance RCT

Recruiting
N/A
1952
Canada
Standard colonoscopy with targeted biopsies
Ottawa Hospital Research Institute
Colonic Neoplasms, Inflammatory Bowel Diseases, Dysplasia
12/25
02/26
Zarychanski, Ryan
TRACTION, NCT04803747: A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery

Active, not recruiting
4
8440
Canada
Tranexamic acid (TXA), Placebo (0.9 % Saline)
University of Manitoba, Canadian Institutes of Health Research (CIHR), Health Sciences Centre Foundation, Manitoba, The Ottawa Hospital
Major Non-cardiac Surgeries
03/24
10/24
ALTER-AKI, NCT04705896: Albumin To Enhance Recovery After Acute Kidney Injury

Recruiting
4
856
Canada
20-25% Albumin fluid (100 mL), 0.9% Normal Saline (100 mL)
Ottawa Hospital Research Institute, The Physicians' Services Incorporated Foundation, The Kidney Foundation of Canada, The Ottawa Hospital Academic Medical Organization (TOHAMO) Innovation Fund Grant., Canadian Institutes of Health Research (CIHR), Canadian Blood Services, Héma-Québec
Acute Kidney Injury, Renal Replacement Therapy, Hypotension, Critical Illness
08/25
10/25
REVISE, NCT03374800 / 2020-000483-27: Re-EValuating the Inhibition of Stress Erosions () Trial

Completed
3
4800
Europe, Canada, US, RoW
Placebo (0.9% saline), normal saline; NaCl 0.9%, Pantoprazole, Protonix
McMaster University, Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group, Australian and New Zealand Intensive Care Society Clinical Trials Group, National Health and Medical Research Council, Australia
Gastrointestinal Hemorrhage (Clinically Important, Upper)
10/23
01/24
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
ATTACC-CAP, NCT05848713: AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Recruiting
3
4000
Canada, US, RoW
Heparin
University of Manitoba, Canadian Institutes of Health Research (CIHR), Research Manitoba, Ozmosis Research Inc., Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Critical Care Trials Group, AVANTI
Community-acquired Pneumonia
03/28
03/29
PLEXSIS, NCT05093075: Therapeutic Plasma Exchange in Septic Shock: a Pilot Study

Recruiting
2
80
NA
Therapeutic Plasma Exchange
University of Manitoba, Canadian Institutes of Health Research (CIHR), Health Sciences Centre Foundation, Manitoba, McMaster University, University of Toronto
Septic Shock
03/26
12/26
MiMICSS, NCT05985525: Microvascular Monitoring in Circulatory Shock and Sepsis

Recruiting
N/A
100
Canada
Skeletal muscle and cerebral NIRS (research device), PortaMon (Artinis Inc, Netherlands), PortaLite (Artinis Inc, Netherlands)
University of Manitoba
Sepsis, Shock, Critical Illness
05/25
05/25
MVTEP2/SOME2, NCT04304651: Screening for Occult Malignancy in Patients with Unprovoked Venous Thromboembolism

Recruiting
N/A
1276
Europe, Canada
Limited cancer screening, Limited cancer screening + FDG PET/CT
University Hospital, Brest, Ministry of Health, France, Canadian Institutes of Health Research (CIHR), Ottawa Hospital Research Institute
Embolism and Thrombosis
09/26
09/30
Wicklow, Brandy A
NCT02818192: Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort Study (National iCARE Study)

Recruiting
N/A
500
Canada
University of Manitoba, Canadian Institutes of Health Research (CIHR)
Type 2 Diabetes, Proteinuria, Stress, Nephropathy
03/26
03/26
NCT05107154: iCARE 2.0: A Pilot Intervention of Dialectical Behavioural Therapy for Youth With Type 2 Diabetes.

Recruiting
N/A
60
Canada
Dialectical Behavioural Therapy
Dr. Brandy Wicklow, Canadian Institutes of Health Research (CIHR)
Diabetes Mellitus Type 2, Childhood-Onset
03/26
03/26
NextGen, NCT04621396: The Next Generation Longitudinal Birth Cohort Diabetes Study

Recruiting
N/A
600
Canada
Observational screening study
University of Manitoba
Type 2 Diabetes, Gestational Diabetes Mellitus
12/26
12/28
Targownik, Laura
No trials found
Oketola, Adebanke
No trials found

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