| Chinot, Olivier |
| Recruiting | 3 | 486 | Europe | Intensified protocol, Stupp protocol | Centre Oscar Lambret, Association de Neuro-Oncologues d'Expression Francaise, Erasme University Hospital | Glioblastoma | 05/25 | 11/27 | | |
SONOBIRD, NCT05902169: Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM |
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| Recruiting | 3 | 560 | Europe, US | SonoCloud-9 (SC9), Carboplatin, CycloButane DiCarboxylic Acid (CBDCA), Lomustine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), Temozolomide, Temodal | CarThera | Glioblastoma, Recurrent Glioblastoma, GBM | 01/28 | 06/28 | | |
POLO, NCT04702581: A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery |
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| Recruiting | 3 | 280 | Europe | PCV chemotherapy, Radiotherapy and PCV chemotherapy | Hospices Civils de Lyon | Oligodendroglioma, Low-grade Oligodendroglioma, 1p19q Codeletion | 12/30 | 12/30 | | |
| Recruiting | 2/3 | 1030 | Europe, Canada, US, RoW | Temozolomide, Temodar, Temodal, Temcad, Lomustine, CCNU, CeeNU, Gleostine, Regorafenib, Stivarga, BAY 73-4506, Radiation, Paxalisib, GDC-0084, VAL-083, Dianhydrogalactitol, VT1021, Troriluzole, BHV-4157, ADI-PEG 20, Pegargiminase | Global Coalition for Adaptive Research, Bayer, Kazia Therapeutics Limited, Kintara Therapeutics, Inc., Biohaven Pharmaceuticals, Inc., Vigeo Therapeutics, Inc., Polaris Group | Glioblastoma | 06/26 | 06/28 | | |
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SonoFIRST, NCT04614493: Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients. |
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| Recruiting | 2 | 66 | Europe | SonoCloud-9 (SC9) device, Temozolomide according Stupp protocol | Assistance Publique - Hôpitaux de Paris | Initial Radiological Diagnosis Eligible for Tumor Resection, Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type), Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide | 03/24 | 03/24 | | |
| Active, not recruiting | 2 | 210 | Europe, US | Berubicin, Berubicin Hydrochloride, Lomustine, Lomustine Capsules, CCNU, CeeNU, Gleostine | CNS Pharmaceuticals, Inc., Worldwide Clinical Trials | Glioblastoma Multiforme, Adult | 12/24 | 03/25 | | |
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OPTIMUM, NCT04945148: Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide |
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| Recruiting | 2 | 640 | Europe | Metformin, Radiation IMRT, Radiation, Temozolomide | Hopital Foch, National Cancer Institute, France | Glioblastoma, IDH-wildtype | 05/28 | 05/28 | | |
| Active, not recruiting | 2 | 20 | Europe, RoW | Sonidegib, Cisplatin, Lomustine, Vincristine, radiotherapy | European Organisation for Research and Treatment of Cancer - EORTC, EORTC-BTG, Sunpharmaceuticals | Medulloblastoma | 04/25 | 04/25 | | |
| Recruiting | 1/2 | 118 | Europe, RoW | Lenalidomide, Revlimid, Ibrutinib, Imbruvica | Institut Curie, National Cancer Institute, France | Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Primary | 02/25 | 02/35 | | |
| Recruiting | 1 | 25 | Europe | Trametinib, Alpelisib, Blood sample, MRI | Assistance Publique Hopitaux De Marseille | Meningioma | 01/26 | 01/26 | | |
MM-Predict, NCT03526822: Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features. |
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| Recruiting | N/A | 100 | Europe | Blood sample, Tumor sample | Assistance Publique Hopitaux De Marseille | Brain Tumor | 07/27 | 07/27 | | |
| BARTOLOMEI, Fabrice |
OPM, NCT04694313: Evaluation of Optical Pumping Magnetometer Sensors for MagnetoEncephaloGraphy Imaging |
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| Completed | N/A | 4 | Europe | OPM | Assistance Publique Hopitaux De Marseille | Epilepsy | 12/22 | 12/22 | | |
SPREAD, NCT03321240: Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia |
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| Recruiting | N/A | 240 | Europe | visual and quantitative SEEG signal analysis, Resective epilepsy surgery procedure | University Hospital, Strasbourg, France | Refractory Epilepsy, Focal Epilepsy, Focal Cortical Dysplasia | 12/22 | 12/22 | | |
| Completed | N/A | 17 | Europe | transcranial direct current stimulation | Assistance Publique Hopitaux De Marseille | Epilepsy | 02/23 | 02/24 | | |
CENOR, NCT05747001: This is a Retrospective Study on the Use of CENOBAMATE as Adjunctive Treatment in Patients Suffering From Epilepsy in Early Access Program in Germany, France and UK |
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| Completed | N/A | 319 | Europe | | Aziende Chimiche Riunite Angelini Francesco S.p.A, Hippocrates Research | Focal Onset Seizure, Epilepsy | 09/23 | 09/23 | | |
| Terminated | N/A | 129 | Europe | Psycho-emotional and semiological measures, Cognitive measures, Physiological measurements, Qualitative measures | Assistance Publique Hopitaux De Marseille | Epilepsy | 06/23 | 06/23 | | |
| Completed | N/A | 12 | Europe | Transcranial stimulation | Assistance Publique Hopitaux De Marseille | Epilepsy | 09/23 | 09/23 | | |
| Enrolling by invitation | N/A | 400 | Europe, Canada, Japan, US, RoW | Stereoelectroencephalography (SEEG) | Duke University, Christian Doppler University Hospital | Epilepsy Intractable | 11/25 | 11/25 | | |
| Recruiting | N/A | 240 | Europe | Multi-scale analysis of physiological brain networks | Assistance Publique Hopitaux De Marseille | Epilepsy | 04/25 | 05/25 | | |
ISEPEE, NCT06271785: Prognostic Value of High-resolution Electrical Source Imaging on the Success of Pediatric Focal Epilepsy Surgery |
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| Recruiting | N/A | 120 | Europe | HR-EEG recording | University Hospital, Angers | Epilepsy in Children | 11/26 | 11/26 | | |
NCT04770337: Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy |
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| Recruiting | N/A | 190 | Europe, US | STARSTIM device, Sham Device | Neuroelectrics Corporation | Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic | 11/25 | 07/26 | | |
| Recruiting | N/A | 140 | Europe | Choice of VNS set of parameters based on the lowest PLI, EEG | Assistance Publique Hopitaux De Marseille | Epilepsy | 06/25 | 12/26 | | |
GALVANI GS-3, NCT06334952: Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic |
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| Recruiting | N/A | 60 | Europe | transcranial direct current stimulation, Research MRI, EEG | Assistance Publique Hopitaux De Marseille, CRMBM-CEMEREM, Institut National de la Santé Et de la Recherche Médicale, France - LTSI, Neuroelectrics Corporation | Epilepsy, Drug Resistant Epilepsy | 12/26 | 11/27 | | |
| Bartoli, Michel |
LUMIFOLLOW, NCT04743180: European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Femoral Artery and Popliteal Artery With 5 Years Follow-up. |
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| Recruiting | N/A | 500 | Europe | LUMINOR© Paclitaxel eluting balloon | iVascular S.L.U. | Angioplasty, Peripheral Arterial Disease, Drug-eluting Balloon, Femoral Artery, Paclitaxel | 06/22 | 06/26 | | |
NCT05141123: Registry of Patients Treated by Preloaded Fenestrated Stent-graft Designs for Complex Endovascular Aortic Procedures |
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| Completed | N/A | 741 | Europe, US | Complex Endovascular Aortic Procedures treated by Preloaded Fenestrated Stent-graft Designs for | IRCCS San Raffaele | Renal Aneurysm, Aneurysm Thoracic, Aneurysm Abdominal | 04/23 | 04/23 | | |
| Bernit, Emmanuelle |
| Completed | 2 | 99 | Europe, RoW | Hydroxycarbamide, Siklos, Placebo Oral Tablet | Theravia | Sickle Cell Disease | 05/24 | 05/24 | | |
| Active, not recruiting | N/A | 2093 | Europe, RoW | Hydroxycarbamide, Siklos, Hydroxyurea | Theravia, International Clinical Trials Association | Sickle Cell Disease | 08/25 | 08/25 | | |
| Seguier, Julie |
| Completed | 2 | 61 | Europe | Nintedanib 150 mg and 100 mg soft capsules, Oral treatment of placebo soft capsule | Hospices Civils de Lyon | Telangiectasia, Hereditary Hemorrhagic, Rendu Osler Disease | 02/23 | 02/23 | | |
| Active, not recruiting | N/A | 2093 | Europe, RoW | Hydroxycarbamide, Siklos, Hydroxyurea | Theravia, International Clinical Trials Association | Sickle Cell Disease | 08/25 | 08/25 | | |
| Recruiting | N/A | 400 | Europe | Questionnaire | Hospices Civils de Lyon | Vascular Anomaly, Osler Rendu Disease, Marfan Syndrome or Related, Lymphedema Primary, Arteriovenous Malformations, Cerebrospinal; Disorder | 02/27 | 11/28 | | |
| Jean, Estelle |
| Completed | 2 | 99 | Europe, RoW | Hydroxycarbamide, Siklos, Placebo Oral Tablet | Theravia | Sickle Cell Disease | 05/24 | 05/24 | | |
| Completed | N/A | 450 | Europe, RoW | | Association Francaise du Lupus et Autres Maladies Auto-immunes (AFL+), Hometrix Health SAS | Lupus Erythematosus, Systemic | 06/24 | 06/24 | | |
