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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Saba, Samir
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation	Recruiting	N/A	520	Europe, Canada, US, RoW	FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone	Boston Scientific Corporation	Persistent Atrial Fibrillation	12/25	12/27
AID MI, NCT05073419: Arrhythmia Detection After MI	Recruiting	N/A	200	US	Standard of Care, Control, ICM Implantation, ICM	Samir Saba, Abbott	Acute Myocardial Infarction	10/25	10/25
CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC	Recruiting	N/A	2650	Europe, Canada, Japan, US, RoW	Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC	Abbott Medical Devices	Atrial Fibrillation, Stroke, Bleeding	08/27	08/30
Sweeny, Susan
CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC	Recruiting	N/A	2650	Europe, Canada, Japan, US, RoW	Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC	Abbott Medical Devices	Atrial Fibrillation, Stroke, Bleeding	08/27	08/30
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy	Recruiting	N/A	620	US	OPTIMIZER Smart System	Impulse Dynamics	Heart Failure	03/26	03/26