UPMC Hillman Cancer Center
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 0 Trials 
9 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Rieth, John
NCT06422806: Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Recruiting
3
180
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Diagnostic Imaging, Medical Imaging, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475
National Cancer Institute (NCI)
Metastatic Undifferentiated Pleomorphic Sarcoma, Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Unresectable Undifferentiated Pleomorphic Sarcoma
06/26
06/26
ARGSARC, NCT05712694: Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects with Leiomyosarcoma

Recruiting
3
300
Canada, US, RoW
ADI PEG20, Pegargiminase, Placebo
Polaris Group
Soft Tissue Sarcoma
12/27
12/27
NCT04040205: Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Recruiting
2
44
US
Abemaciclib, Verzenio
Medical College of Wisconsin
Chondrosarcoma, Osteosarcoma, Soft Tissue Sarcoma
06/25
06/26
NCT02453191: TVEC and Preop Radiation for Sarcoma (4 ml Dose)

Completed
1/2
30
US
Talimogene Laherparepvec, Radiotherapy
University of Iowa, Amgen
Soft Tissue Sarcoma
01/19
03/23
NCT04599062: TVEC and Preop Radiation for Sarcoma (8 ml Dose)

Active, not recruiting
1/2
8
US
Talimogene Laherparepvec, Radiotherapy
John Rieth, Amgen
Soft Tissue Sarcoma
02/23
11/24
NCT03957551: Cabozantinib and Pembrolizumab for Advanced Metastatic Melanoma

Active, not recruiting
1/2
28
US
Cabozantinib, XL184, COMETRIQ™, Cabometyx®, Pembrolizumab, Keytruda
John Rieth, Exelixis, University of Iowa
Advanced Metastatic Melanoma
06/24
12/26
NCT04634227: Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

Recruiting
1
40
US
Ascorbate
University of Iowa, Mohammed Milhem, MBBS
Sarcoma, Soft Tissue Sarcoma, Unresectable Soft Tissue Sarcoma, Metastatic Bone Tumor, Bone Sarcoma
08/25
08/25
NCT06660810: Neoadjuvant Intralesional Injection of Talimogene Laherparepvec

Not yet recruiting
1
30
US
Talimogene Laherparepvec, Neoadjuvant Radiation, Surgery
John Rieth, Amgen
Soft Tissue Sarcoma, Sarcoma,Soft Tissue
11/28
11/33
NCT06113809: Palbociclib and Pembrolizumab in Undifferentiated Pleomorphic Sarcoma (UPS)

Recruiting
1
8
US
Palbociclib, Pembrolizumab
John Rieth
Undifferentiated Pleomorphic Sarcoma
07/28
07/28

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