University Hospital of South Manchester & Manchester Royal Infirmary
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 10 Trials 
17 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Ross, Paul
MOUNTAINEER-03, NCT05253651 / 2021-002672-40: A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Recruiting
3
400
Europe, Canada, Japan, US, RoW
tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil
Seagen Inc., Merck Sharp & Dohme LLC
Colorectal Neoplasms
08/25
04/28
SAFIR-ABC10, NCT05615818: Personalized Medicine for Advanced Biliary Cancer Patients

Recruiting
3
800
Europe
Futibatinib, Ivosidenib, Tibsovo, Zanidatamab, Trastuzumab, Zercepac, Neratinib, Nerlynx, Encorafenib, Braftovi, Binimetinib, Mektovi, Niraparib, Zejula, Cisplatin, Gemcitabine
UNICANCER, Cancer Research UK & UCL Cancer Trials Centre, Belgian Group of Digestive Oncology, National Cancer Institute, France, Cancer Research UK, Taiho Oncology, Inc., Servier, Zymeworks BC Inc., Accord Healthcare, Inc., Pierre Fabre Medicament
Biliary Tract Neoplasms
06/27
06/28
TRIPP-FFX, NCT05466799: FOLFIRINOX Versus OncoSil™ in Addition to FOLFIRINOX in Patients With Locally Advanced Pancreatic Adenocarcinoma

Recruiting
2
80
Europe, RoW
FOLFIRINOX chemotherapy, Folinic Acid, 5-FU, Oxaliplatin, Irinotecan, OncoSil™, Phosphorous-32 microparticles
OncoSil Medical Limited
Locally Advanced Pancreatic Cancer
06/25
09/25
PRIMER-1, NCT05185739: Perioperative Pembrolizumab and Lenvatinib in Resectable Hepatocellular Carcinoma (HCC)

Recruiting
2
60
Europe
Pembrolizumab, Lenvatinib, Pembrolizumab and Lenvatinib
University College, London, Merck Sharp & Dohme LLC
Hepatocellular Carcinoma
07/28
07/30
GARNET, NCT02715284: Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Checkmark MFDS approved in Korea in adult patients with recurrent or advanced dMMR/MSI-H 2L endometrial cancer
Dec 2022 - Dec 2022: MFDS approved in Korea in adult patients with recurrent or advanced dMMR/MSI-H 2L endometrial cancer
Checkmark Result from GARNET trial for dMMR endometrial cancer and other solid tumors at ESMO 2022
Sep 2022 - Sep 2022: Result from GARNET trial for dMMR endometrial cancer and other solid tumors at ESMO 2022
Checkmark Approved for recurrent or advanced endometrial cancer
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Recruiting
1
740
Europe, Canada, US, RoW
Dostarlimab
Tesaro, Inc.
Neoplasms
05/26
10/27
TRACC, NCT04050345: Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Recruiting
N/A
1000
Europe
Royal Marsden NHS Foundation Trust
Colorectal Cancer
07/29
07/31
OSPREY, NCT04493632: is a Post-market, Global, Multicentre, Observational, Prospective Registry.

Recruiting
N/A
500
Europe
OncoSil Medical Limited
Pancreatic Neoplasm, Digestive System Neoplasm, Neoplasms by Site, Neoplasms, Endocrine Gland Neoplasm, Digestive System Disease, Pancreatic Diseases, Endocrine System Diseases
11/25
10/27
SIRtain, NCT05967143: Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors ( Registry)

Recruiting
N/A
845
Europe
SIRT
Sirtex Medical
Unresectable Hepatocellular Carcinoma (HCC), Liver Metastases From Colorectal Cancer (mCRC)
06/28
06/29
Piper, Lindsay
TRACC, NCT04050345: Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Recruiting
N/A
1000
Europe
Royal Marsden NHS Foundation Trust
Colorectal Cancer
07/29
07/31
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Abulafi, Muti
TRACC, NCT04050345: Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Recruiting
N/A
1000
Europe
Royal Marsden NHS Foundation Trust
Colorectal Cancer
07/29
07/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Duff, Sarah
TRACC, NCT04050345: Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Recruiting
N/A
1000
Europe
Royal Marsden NHS Foundation Trust
Colorectal Cancer
07/29
07/31
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Shillito, Lauren
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31

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