National Cancer Center, Korea
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 159 Trials 
194 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Kim, Tae Won
NEMO, NCT03128021: Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response

Completed
4
57
US
Escitalopram Pill, Lexapro, Placebo, Levomilnacipran Pill, Fetzima
Howard Aizenstein, Weill Cornell Institute of Geriatric Psychiatry, National Institute of Mental Health (NIMH)
Major Depressive Disorder
06/23
08/23
OPTIMIZE-APT, NCT05418556: Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Recruiting
4
3944
RoW
aspirin, clopidogrel, prasugrel, ticagrelor
Asan Medical Center
Coronary Artery Disease
08/27
12/28
NCT06545526: Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis

Recruiting
3
28
RoW
celecoxib monotherapy, celecoxib and metformin combination
Yonsei University
Familial Adenomatous Polyposis
06/26
06/26
VIVID-2, NCT04232553 / 2019-002687-27: A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

Recruiting
3
778
Europe, Canada, Japan, US, RoW
Mirikizumab, LY3074828
Eli Lilly and Company
Crohn's Disease
11/24
12/26
NCT04296851: Niclosamide for Familial Adenomatous Polyposis

Recruiting
2
72
RoW
Niclosamide, placebo
Yonsei University
Familial Adenomatous Polyposis
12/22
02/23
NCT03435107: Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer

Completed
2
33
RoW
Durvalumab
Asan Medical Center
Metastatic Colorectal Cancer
04/23
04/23
DYNAMIC, NCT04954339: DYNAmic Immune Microenvironment of HCC Treated with AtezolIzumab Plus BevaCizumab

Recruiting
2
45
RoW
Aatezolizumab plus Bevacizumab, Ticentriq plus Avastin
Tae Won Kim
Hepatocellular Carcinoma
06/26
12/26
SPECTRUM, NCT05253118: Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS)

Recruiting
2
28
RoW
Tislelizumab, BGB-A317, Pemetrexed
Seoul National University Hospital, Gyeongsang National University Hospital, Kyunghee University Medical Center, Inje University Haeundae Paik Hospital, Chungnam National University Hospital
DLBCL
12/25
02/26
EPCORE DLBCL-3, NCT05660967: Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma

Recruiting
2
180
Europe, Japan, US, RoW
Epcoritamab, GEN3013, DuoBody®-CD3×CD20, EPKINLY™, Lenalidomide, Revlimid®
Genmab, AbbVie
Diffuse Large B-Cell Lymphoma
01/26
03/27
NCT05503797: A Study to Assess the Efficacy and Safety of FORE8394 in Participants with Cancer Harboring BRAF Alterations

Recruiting
2
250
Europe, Canada, US, RoW
Plixorafenib, FORE8394, PLX8394, Cobicistat, TYBOST(R)
Fore Biotherapeutics
Cancer Harboring BRAF Alterations
06/25
08/26
ACE, NCT05741060: Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers

Active, not recruiting
2
372
US
S-equol, Equelle, Placebo
Akira Sekikawa, National Institute on Aging (NIA)
Arterial Stiffness, White Matter Lesions, Cognitive Decline
10/26
01/27
AZUR-1, NCT05723562 / 2022-003289-18: A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer

Active, not recruiting
2
154
Europe, Canada, Japan, US, RoW
Dostarlimab, JEMPERLI, dostarlimab-gxly, TSR-042, GSK4057190A
GlaxoSmithKline, GlaxoSmithKline Research & Development Ltd
Neoplasms, Rectal
11/26
10/29
NCT04696848: The Efficacy and Safety of CKD516 Combined With Durvalumab in Patient Refractory Solid Tumors

Terminated
1/2
25
RoW
CKD-516 plus Durvalumab, CKD-516 plus MEDI4736
Tae Won Kim
Colorectal Cancer, Solid Tumor
03/23
03/23
KEYNOTE-877, NCT03674567: Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab

Active, not recruiting
1/2
323
US, RoW
FLX475, pembrolizumab (KEYTRUDA®)
RAPT Therapeutics, Inc., Merck Sharp & Dohme LLC
Advanced Cancer
09/24
01/25
NCT04903873: A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

Recruiting
1/2
110
US, RoW
EU101
Eutilex
Solid Tumor, Renal Cell Cancer Metastatic, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Prostate Cancer
09/25
12/25
METex14, NCT04868877 / 2021-000203-20: Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Recruiting
1/2
576
Europe, US, RoW
MCLA-129, bispecific, Osimertinib, Tagrisso, Chemotherapy
Merus N.V.
Non-Small Cell Lung Cancer Metastatic, Gastric Cancer, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer
03/26
03/27
NCT05394831: A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC

Recruiting
1/2
150
US, RoW
JIN-A02
J Ints Bio
EGFR Mutant Advanced Non-small Cell Lung Cancer
07/24
11/25
IDE397-001, NCT04794699: Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Recruiting
1
180
Europe, US, RoW
IDE397, Docetaxel, Paclitaxel, Sacituzumab govitecan
IDEAYA Biosciences
Solid Tumor
12/26
03/27
NCT03284502: HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid Tumors

Active, not recruiting
1
148
RoW
HM95573, cobimetinib, HM95573, cetuximab
Hanmi Pharmaceutical Company Limited
Locally Advanced Solid Tumor, Metastatic Solid Tumor
09/24
12/24
NCT05159440: First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer

Active, not recruiting
1
70
US, RoW
TORL-2-307-MAB
TORL Biotherapeutics, LLC, Translational Research in Oncology
Advanced Solid Tumor, Gastric Cancer, Pancreas Cancer, Gastroesophageal Junction Adenocarcinoma
12/24
12/25
NCT05156866: First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer

Recruiting
1
70
US, RoW
TORL-2-307-ADC
TORL Biotherapeutics, LLC, Translational Research in Oncology
Advanced Solid Tumor, Gastric Cancer, Pancreas Cancer, Gastroesophageal Junction Adenocarcinoma
01/25
01/26
ELVN-002-001, NCT05650879: ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer

Recruiting
1
198
Europe, US, RoW
ELVN-002, Fam-Trastuzumab Deruxtecan-Nxki, Enhertu, T-DXd, Trastuzumab emtansine, Kadcyla, T-DM1
Enliven Therapeutics
HER2 Mutant Non-small Cell Lung Cancer, HER2-positive Metastatic Breast Cancer, HER2 Gene Mutation, HER2 Amplification
07/26
07/26
RELIF-C, NCT02865369: Regression of Liver Fibrosis After Daclatasvir and Asunaprevir Treatment

Not yet recruiting
N/A
103
RoW
Daclatasvir and Asunaprevir, Daclatasvir and Asunaprevir combined treatment for 24 weeks
Sang Gyune Kim, Seoul National University Boramae Hospital, Severance Hospital, Inha University Hospital, Korea University, Gachon University Gil Medical Center, Hanyang University Seoul Hospital, Ewha Womans University Mokdong Hospital, Bristol-Myers Squibb
Chronic Hepatitis C
12/18
12/22
NCT04656405: Efficacy of Online Real-time CPR Training

Recruiting
N/A
180
RoW
Online real-time quality measurement and feedback video-based CPR training, Online real-time feedback video-based CPR training without quality measurement, Conventional CPR training
Seoul National University Hospital
Cardiopulmonary Resuscitation, Education
12/21
03/22
NCT04239794: The Influence of Type of Anesthesia on Postoperative Pain

Active, not recruiting
N/A
468
RoW
Propofol, Propofol 2%, Sevoflurane, Sevoflurane inhalant product
Seoul National University Hospital
Colo-rectal Cancer, Anesthesia
12/23
01/24
NCT04203849: Prospective Cohort Study of Breast Cancer Patients Treated With Radiotherapy

Enrolling by invitation
N/A
5000
RoW
National Cancer Center, Korea
Breast Cancer
06/22
06/34
NCT05100485: Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)

Completed
N/A
1000
RoW
Esophagogasrtoduodendoscopy, Hepatic venous pressure gradient
Hepatopancreatobiliary Surgery Institute of Gansu Province, Tianjin Second People's Hospital, The Third People's Hospital of Taiyuan, Ehime University Graduate School of Medicine, Korea University Ansan Hospital, Hyogo Medical University, Zagazing University Faculty of Medicine, Institute of Liver and Biliary Sciences (ILBS), Changi General Hospital, Ruijin Hospital
Compensated Advanced Chronic Liver Disease
01/23
01/23
NCT05559502: High Flow Nasal Oxygenation vs Endotracheal Intubation on Recovery Profiles in Laryngeal Microsurgery

Recruiting
N/A
52
RoW
HFNO group, Optiflow, ET group, Portex, Smiths Medical International Ltd., South East England, United Kingdom
Ajou University School of Medicine
Cough
06/24
06/24
NCT03969823: Whole Genomic Landscape of Advanced EGFR-mutant NSCLC

Active, not recruiting
N/A
148
RoW
Tagrisso, Osimertinib
Seoul National University Hospital, Seoul National University Bundang Hospital, SMG-SNU Boramae Medical Center
Locally Advanced or Metastatic NSCLC
09/25
12/25
NCT06205212: High-flow Nasal Oxygenation During Preoxygenation and Atelectasis

Recruiting
N/A
92
RoW
high-flow nasal oxygen, facemask
Seoul National University Hospital, SMG-SNU Boramae Medical Center
Anesthesia, General, Pulmonary Atelectasis
10/24
10/24
ICARUS, NCT05805280: IntravasCular Imaging-Guided Versus AngiogRaphy-GUided Drug-Eluting Stent Implantation for Fermoropopliteal Artery Disease

Recruiting
N/A
100
RoW
intravascular ultrasound-guided group, angiography-guided group
Asan Medical Center
Femoropopliteal Disease
12/24
12/25
DREAM-CCTA, NCT05801432: A Study to Evaluate Coronary Atherosclerosis in Patients With Diabetes Mellitus

Recruiting
N/A
511
RoW
Asan Medical Center
Diabetes Mellitus
12/24
12/24
NCT06216912: Gastric Volume in Paralyzed Obese Patients After High-flow Nasal Oxygen Therapy

Recruiting
N/A
60
RoW
Seoul National University Hospital, SMG-SNU Boramae Medical Center
Undefined
01/25
01/25
OBE-KMT22-01, NCT06250608: Evaluation of rSO2 Between Frontal Lesion Area and Normal Area of Brain by NIRSITX Using NIRS in Acute Ischemic Stroke Patients.

Not yet recruiting
N/A
35
RoW
Pulse oximeter, NIRSITX
OBELAB, Inc., Helptrial Inc.
Acute Ischemic Stroke Patients
12/24
12/24
roboticPCI, NCT05981859: AVIAR(MX-02) Robotic-assisted Percutaneous Coronary Intervention

Completed
N/A
21
RoW
Asan Medical Center, LN Robotics
Percutaneous Coronary Intervention
03/24
04/24
NCT06441175: Effectiveness of Cricoid Pressure During Videolaryngoscopy Versus Direct Laryngoscopy

Not yet recruiting
N/A
140
NA
Intubation device order
Seoul National University Hospital, SMG-SNU Boramae Medical Center
Cricoid Pressure
07/25
07/26
NCT06076083: Multi-omics Database for Integrative Microbiome Analysis in a Cohort of Korean Patients With Ankylosing Spondylitis

Recruiting
N/A
600
RoW
Tae-Hwan Kim, Kyunghee University Medical Center
Ankylosing Spondylitis
12/25
12/27
NCT04259398: Anesthesia and Cancer Study: Colon Cancer

Active, not recruiting
N/A
797
RoW
Propofol, Sevoflurane
Seoul National University Hospital, Korean Society of Anesthesiologists, Bundang Seoul National University Hospital, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, Seoul St. Mary's Hospital, Seoul National University Boramae Hospital
Cancer of Colon, Anesthesia
05/28
05/28
ASSIST, NCT05529459: Anatomic Versus Physiologic Guidance for Complete Revascularization With DES Eluting in Patients With CAD

Recruiting
N/A
2400
RoW
Percutaneous Coronary Intervention
Seung-Whan Lee, M.D., Ph.D., Biotronik Korea Co., Ltd
Coronary Disease
12/26
07/30
PROVE-DM, NCT05579626: Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus

Recruiting
N/A
4000
RoW
high-intensity statin arm, low-intensity statin plus ezetimibe
Seung-Whan Lee, M.D., Ph.D., Yuhan Corporation
Pre Diabetes, ASCVD
12/27
12/27
NCT04466189: Prospective Cohort Study of Pancreatic Cancer Patients Treated With Proton Beam Therapy

Enrolling by invitation
N/A
120
RoW
National Cancer Center, Korea
Pancreas Cancer
08/28
08/28
PTA, NCT06022653: Asan Aorta and Peripheral Registry

Recruiting
N/A
6000
RoW
Treatment, Intervention
Asan Medical Center
Aorta Disease, Peripheral Artery Disease
12/34
12/44
NCT05467930: CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2

Recruiting
N/A
1000
US
Survey, Medical History Review, Sample Collection
Columbia University, Gilead Sciences
COVID-19, SARS CoV 2 Infection
05/25
05/26
NCT04466124: Prospective Cohort Study of Liver Cancer Patients Treated With Proton Beam Therapy

Enrolling by invitation
N/A
500
RoW
Liver Cancer Patients Treated With Proton Beam Therapy
National Cancer Center, Korea
Liver Cancer
08/28
08/28
NCT05213962: Local and Regional Radiotherapy for Nipple Sparing Mastectomy With Implant

Enrolling by invitation
N/A
128
RoW
National Cancer Center, Korea
Breast Cancer
12/28
12/28
Lee, Jong Mog
OPTIMIZE-APT, NCT05418556: Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Recruiting
4
3944
RoW
aspirin, clopidogrel, prasugrel, ticagrelor
Asan Medical Center
Coronary Artery Disease
08/27
12/28
NCT04497142: Effect of Perampanel on Peritumoral Hyperexcitability in HGG

Completed
1/2
12
US
Perampanel, E2007, Fycompa, Standard of Care, Standard treatment (typically the anti-seizure medication levetiracetam)
Dana-Farber Cancer Institute, National Cancer Institute (NCI), Eisai Inc.
Glioma, Malignant, Surgery, Seizures
05/23
05/23
NCT04409080: REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Recruiting
1/2
33
Europe, US, RoW
REGN7257
Regeneron Pharmaceuticals
Severe Aplastic Anemia (SAA)
01/26
05/26
CENOBITE, NCT06352723: Cenobamate in the Intensive Care Unit

Not yet recruiting
1
10
US
Cenobamate
Brigham and Women's Hospital
Epilepsy, Neurologic Disorder
12/24
06/25
ASSURE, NCT03306901: Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma

Active, not recruiting
N/A
240
RoW
Esophagectomy, 5-fluorouracil, 5-FU, Cisplatin, Radiation therapy
Samsung Medical Center, Ministry of Health & Welfare, Korea
Esophageal Cancer
12/25
12/33
ICARUS, NCT05805280: IntravasCular Imaging-Guided Versus AngiogRaphy-GUided Drug-Eluting Stent Implantation for Fermoropopliteal Artery Disease

Recruiting
N/A
100
RoW
intravascular ultrasound-guided group, angiography-guided group
Asan Medical Center
Femoropopliteal Disease
12/24
12/25
Korus, NCT06135285: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP)

Not yet recruiting
N/A
10
US
Control subjects
Brigham and Women's Hospital
Epilepsy
06/27
06/27
ICECAP, NCT04217551: Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Recruiting
N/A
1800
US
Therapeutic Hypothermia
University of Michigan, Johns Hopkins University, Medical University of South Carolina, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS)
Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
07/28
08/28
Kim, Moon Soo
NCT01937806: Phase 3 and Extensional Study of Besifovir

Active, not recruiting
3
197
RoW
besifovir 150mg, tenofovir 300mg
IlDong Pharmaceutical Co Ltd
Chronic Hepatitis B
02/16
01/23
NAVIGATE, NCT04365868: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Active, not recruiting
2b
357
Europe, Canada, US, RoW
belapectin, GR-MD-02, galactoarabino rhamnogalacturonate, Placebo
Galectin Therapeutics Inc.
Prevention of Esophageal Varices, NASH - Nonalcoholic Steatohepatitis, Cirrhosis
12/24
12/24
NCT05532124: Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups.

Recruiting
2
49
RoW
LAENNEC (Human Placenta Hydrolysate), normal saline
Green Cross Wellbeing
Chronic Liver Disease
03/23
06/23
NCT05911841: A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis

Recruiting
2
260
Europe, Canada, Japan, US, RoW
LY3454738, Placebo
Eli Lilly and Company
Atopic Dermatitis
06/25
03/26
SOLAR, NCT05673772: Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer

Recruiting
2
364
RoW
short-course radiotherapy, mFOLFOX6, Chemoradiotherapy, TME surgery
Kyungpook National University Hospital, National Cancer Center, Korea
Rectal Cancer
12/24
12/29
RELIF-C, NCT02865369: Regression of Liver Fibrosis After Daclatasvir and Asunaprevir Treatment

Not yet recruiting
N/A
103
RoW
Daclatasvir and Asunaprevir, Daclatasvir and Asunaprevir combined treatment for 24 weeks
Sang Gyune Kim, Seoul National University Boramae Hospital, Severance Hospital, Inha University Hospital, Korea University, Gachon University Gil Medical Center, Hanyang University Seoul Hospital, Ewha Womans University Mokdong Hospital, Bristol-Myers Squibb
Chronic Hepatitis C
12/18
12/22
Han, Ji-Youn
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Recruiting
3
1016
Europe, Canada, Japan, US, RoW
LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed
Eli Lilly and Company, Loxo Oncology, Inc.
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
10/26
10/29
LIBRETTO-432, NCT04819100 / 2020-005191-35: A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

Recruiting
3
170
Europe, Canada, Japan, US, RoW
Selpercatinib, LY3527723, LOXO-292, Placebo
Loxo Oncology, Inc., Eli Lilly and Company
Carcinoma, Non-Small-Cell Lung
05/27
08/32
NCT01470716: Neoadjuvant Erlotinib for Operable Stage II or IIIA NSCLC With EGFR Mutations

Active, not recruiting
2
26
RoW
Erlotinib, treatment arm
National Cancer Center, Korea, Hoffmann-La Roche
NSCLC Stage II, NSCLC, Stage IIIA
12/21
06/22
AvaTa, NCT03126799: A Study of Tarceva vs. Avastin+Tarceva for Advanced NSCLC With EGFR m(+)

Active, not recruiting
2
128
RoW
Erlotinib plus Bevacizumab, Tarceva plus Avastin, Erlotinib, Tarceva
National Cancer Center, Korea, Roche Korea co.,Ltd.
EGFR Positive Non-small Cell Lung Cancer
12/21
07/23
NCT03808480: Nivolumab After Cyclophosphamide and Doxorubicin Induction Therapy in NSCLC With PD-L1<10%

Recruiting
2
22
RoW
CA and Nivolumab, Opdivo
National Cancer Center, Korea
Non-small Cell Lung Cancer
05/22
05/22
NCT01441349: Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer

Active, not recruiting
2
192
RoW
IP chemotherapy, IP, IP chemotherapy plus simvastatin, IPSimva
National Cancer Center, Korea
Small Cell Lung Carcinoma
10/22
12/22
NCC-2018-0232, NCT03612154: Study of Lorlatinib in ROS1 Rearranged NSCLC

Recruiting
2
35
RoW
Lorlatinib
National Cancer Center, Korea
Nonsmall Cell Lung Cancer
12/22
12/23
NCT03262454: Sequential Hypofractionated Radiotherapy Followed by Anti-PD-L1 Atezolizumab for SCLC

Recruiting
2
35
RoW
Atezolizumab, Tecentriq
National Cancer Center, Korea, Roche Korea co.,Ltd.
Small Cell Lung Cancer Recurrent
02/23
07/24
NCT04074993: Brigatinib in ALK-positive NSCLC Identified Via Blood-based Assays

Active, not recruiting
2
35
RoW
Brigatinib
JI-YOUN HAN, Seoul National University Hospital, Severance Hospital, Seoul National University Bundang Hospital
Non Small Cell Lung Cancer
01/25
03/25
NCT05541822: To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation

Recruiting
2
40
US, RoW
ABN401
Abion Inc
Advanced Solid Tumors
04/25
08/25
STEREO, NCT04908956: Osimertinib and Locally Ablative Radiotherapy in Patients With Synchronous Oligo-metastatic EGFR Mutant NSCLC

Terminated
2
6
Europe, RoW
Osimertinib, Tagrisso, Stereotactic Body Radiation Therapy (SBRT)
ETOP IBCSG Partners Foundation, AstraZeneca
NSCLC Stage IV, EGFR Gene Mutation
10/23
02/24
LIBRETTO-001, NCT03157128 / 2017-000800-59: A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer

Checkmark From LIBRETTO-001 trial in RET fusion-positive NSCLC
Aug 2020 - Aug 2020: From LIBRETTO-001 trial in RET fusion-positive NSCLC
Checkmark Updated interim data for RET mut medullary & RET fusion thyroid cancers [LIBRETTO-001]
Oct 2018 - Oct 2018: Updated interim data for RET mut medullary & RET fusion thyroid cancers [LIBRETTO-001]
Active, not recruiting
1/2
856
Europe, Canada, Japan, US, RoW
LOXO-292, Selpercatinib, LY3527723
Loxo Oncology, Inc., Eli Lilly and Company
Non-Small Cell Lung Cancer, Medullary Thyroid Cancer, Colon Cancer, Any Solid Tumor
02/25
02/26
REZILIENT1, NCT04036682: A Phase 1/2 Trial of CLN-081 in Patients with Non-Small Cell Lung Cancer

Checkmark Data from a trial for NSCLC
Jan 2022 - Jan 2022: Data from a trial for NSCLC
Active, not recruiting
1/2
284
Europe, Japan, US, RoW
CLN-081, TAS6417; zipalertinib
Cullinan Therapeutics Inc.
Non Small Cell Lung Cancer, EGFR Exon 20 Mutation
12/24
12/24
ARROS-1, NCT05118789 / 2021-002477-26: A Study of NVL-520 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement

Recruiting
1/2
359
Europe, Canada, Japan, US, RoW
NVL-520
Nuvalent Inc., Nuvalent, Inc.
Locally Advanced Solid Tumor, Metastatic Solid Tumor
10/25
10/26
ALKOVE-1, NCT05384626 / 2022-000122-21: A Study of NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation

Recruiting
1/2
470
Europe, Canada, Japan, US, RoW
NVL-655
Nuvalent Inc., Nuvalent, Inc.
Locally Advanced Solid Tumor, Metastatic Solid Tumor
02/26
03/26
NCT04052971: To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation

Recruiting
1
78
RoW
ABN401- Escalation Phase, ABN401- Expansion Phase
Abion Inc, Novotech (Australia) Pty Limited
Advanced Solid Tumors
12/24
12/24
IDE397-001, NCT04794699: Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Recruiting
1
180
Europe, US, RoW
IDE397, Docetaxel, Paclitaxel, Sacituzumab govitecan
IDEAYA Biosciences
Solid Tumor
12/26
03/27
Kim, Min Chan
NCT05664555: Dose Optimization for Safe and Efficient Fluorescein Angiography (DOSE Study)

Completed
4
144
RoW
Fluorescein Sodium
Seoul National University Bundang Hospital
Retinal Disease
03/24
03/24
PhALLCON, NCT03589326 / 2018-000397-30: A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

Checkmark Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
Sep 2019 - Sep 2019: Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
Checkmark Initiation of new trial in Ph+ ALL
Jul 2018 - Jul 2018: Initiation of new trial in Ph+ ALL
Active, not recruiting
3
245
Europe, Canada, Japan, US, RoW
Ponatinib, Iclusig, Imatinib, Gleevec, Vincristine, Dexamethasone, Cytarabine, Methotrexate, Prednisone
Takeda
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
08/22
07/27
innovaTV 301, NCT04697628 / 2019-001655-39: Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Active, not recruiting
3
502
Europe, Canada, Japan, US, RoW
tisotumab vedotin, TIVDAK, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed
Seagen Inc., Genmab
Cervical Cancer
07/23
08/25
FLORA-4, NCT04498117 / 2020-002270-26: Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

Active, not recruiting
3
615
Europe, Canada, US, RoW
Oregovomab, MAb-B43.13, Paclitaxel, Taxol, Carboplatin, Paraplatin, Placebo
CanariaBio Inc., Gynecologic Oncology Group, Iqvia Pty Ltd
Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Fallopian Tube Neoplasms, Fallopian Tube Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Peritoneal Cancer, Peritoneal Carcinoma, Peritoneal Neoplasms
09/25
08/27
NRG-GY019, NCT04095364: Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recruiting
3
450
Europe, Canada, US, RoW
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Imaging Technique, Diagnostic Imaging Technique, Image Type, Imaging, Imaging (procedure), imaging procedure, Imaging Procedures, imaging type, IMAGING_METHOD, imaging_type, Medical Imaging, Type of imaging, Letrozole, CGS 20267, Femara, Fempro, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat
NRG Oncology, National Cancer Institute (NCI)
Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8, Stage II Ovarian Cancer AJCC v8, Stage II Primary Peritoneal Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
02/27
02/28
CRESCENDO, NCT06072131: To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Recruiting
3
504
Europe, US, RoW
Belinostat Injection, Beleodaq®, Pralatrexate Injection, Folotyn®, CHOP, Cyclophosphamide, Hydroxydaunorubicin (doxorubicin), Oncovin (vincristine), and Prednisone, COP, Cyclophosphamide, Oncovin (vincristine), and Prednisone
Acrotech Biopharma Inc.
Peripheral T Cell Lymphoma
07/30
11/30
NCT04696120: Effects of APIXaban on BRAIN Protection in Patients With Sinus Rhythm and Heart Failure: APIXBRAIN-HF Trial

Not yet recruiting
2
200
RoW
Apixaban, apixaban 5mg or 2.5mg bid, Placebo, placebo bid
Korea University Guro Hospital, Dt&Sanomedics
Heart Failure, Sinus Rhythm, Cerebrovascular Disease
08/22
02/23
NCT05665023: Bevacizumab Plus Modiifed FOLFIRINOX in Ovarian, Fallopian Tube, or Primary Peritoneal Mucinous Carcinoma

Recruiting
2
37
RoW
Bevacizumab + modified FOLFIRINOX
Yonsei University
Mucinous Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
02/24
02/25
NCT05359861: Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Active, not recruiting
2
134
US, RoW
SRF388, Atezolizumab, Tecentriq, Bevacizumab, Avastin, Placebo
Coherus Biosciences, Inc.
Hepatocellular Carcinoma
05/25
05/26
NCT04903873: A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors

Recruiting
1/2
110
US, RoW
EU101
Eutilex
Solid Tumor, Renal Cell Cancer Metastatic, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Prostate Cancer
09/25
12/25
BOLD-100-001, NCT04421820: BOLD-100 in Combination with FOLFOX for the Treatment of Advanced Solid Tumours

Recruiting
1/2
220
Europe, Canada, US, RoW
BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion), BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation)
Bold Therapeutics, Inc.
Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
06/26
09/26
NCT05113693: Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-393

Completed
1
33
RoW
CKD-393, CKD-501, D759, H053
Chong Kun Dang Pharmaceutical
Type 2 Diabetes
12/21
12/21
NCT05113849: Study to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine (IN-B009) in Healthy Adults (COVID-19)

Recruiting
1
40
RoW
IN-B009 (Low-dose), IN-B009 (High-dose)
HK inno.N Corporation
COVID-19
02/23
02/23
EARLY-UNLOAD, NCT04775472: Early Left Atrial Septostomy Versus Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation

Completed
N/A
116
RoW
Early left atrial septostomy within 12 hours after VA-ECMO implantation, Selective left atrial septostomy
Chonnam National University Hospital
Cardiogenic Shock
03/22
10/23
PLOTS, NCT04066699: Percutaneous Localization: Open-label Registry of Thoracic Surgery

Completed
N/A
70
US
Percutaneous localization of suspicious lung lesion(s) using electromagnetic navigation and tools., SPiN Thoracic Navigation System™, Veran System
Veran Medical Technologies
Lung Lesion(s) Requiring Evaluation, Pulmonary Metastasis, Pulmonary Nodule, Solitary, Peripheral Lung Lesions
01/23
02/23
VISION, NCT04151615: VMP Regimen - Safety, Efficacy, and Optimal Dose Finding Study for Patients With Multiple Myeloma

Completed
N/A
203
RoW
Boryung Pharmaceutical Co., Ltd
Multiple Myeloma
01/23
01/23
NCT04853563: Comparison of PEEP in Acute Decompensated Heart Failure

Recruiting
N/A
120
RoW
PEEP
Asan Medical Center
Heart Decompensation, Mechanical Ventilation Pressure High
07/23
04/24
NCT03763604: Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer

Available
N/A
Europe, Canada, RoW
Abemaciclib, LY2835219
Eli Lilly and Company
Metastatic Breast Cancer
 
 
NCT05629611: Efficacy and Safety Evaluation of Vi-sealer

Recruiting
N/A
280
RoW
Vi-Sealer, Ligasure, Other AHD
Hyun Park
Benign Gynecologic Neoplasm
12/24
10/25
NCT04322851: B-line by Lung US in Patients With Acute Decompensated Heart Failure

Recruiting
N/A
300
RoW
Lung ultrasound
Asan Medical Center
Heart Failure
03/24
03/24
FRAME-AMI3, NCT06227754: OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts

Recruiting
N/A
1500
RoW
Angiography-guided PCI group, Optical coherence tomography-guided PCI group
Chonnam National University Hospital, Samsung Medical Center
ST Elevation Myocardial Infarction, Myocardial Infarction
12/28
12/29
ORIGO, NCT06597175: Evaluating Investigational Medical Device for Breast Tumor Diagnosis Using Diffusion Optical Spectroscopy

Recruiting
N/A
300
RoW
ORIGO
Olive Healthcare
Breast Cancer, Breast Tumor, Mammary Carcinoma, Human
10/24
10/24
NCT06537752: A Study to Evaluate Ethanol-induced Symptoms and Safety in Breast Cancer Patients

Recruiting
N/A
1052
RoW
Boryung Pharmaceutical Co., Ltd
Breast Cancer
10/26
10/26
EARLY-HF, NCT04810806: Timing of Coronary Angiography in NSTE-ACS With ADHF

Terminated
N/A
316
RoW
Immediate coronary angiography within 2 hours after randomization, Delayed coronary angiography after stabilization of heart failure
Chonnam National University Hospital
Heart Failure, Acute Coronary Syndrome
03/24
03/24
 

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