| Recruiting | 4 | 61 | US | Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide) | GT Medical Technologies, Inc. | Glioblastoma | 07/27 | 12/27 | | |
NRG-BN009, NCT04588246: Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery |
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| Terminated | 3 | 19 | US | Memantine, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | NRG Oncology, National Cancer Institute (NCI) | Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Digestive System Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8, Recurrent Brain Neoplasm, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8 | 08/24 | 08/24 | | |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
NRG-BN003, NCT03180268: Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery |
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| Recruiting | 3 | 148 | Canada, Japan, US, RoW | Clinical Observation, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RADIATION, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation | NRG Oncology, National Cancer Institute (NCI) | Grade II Meningioma, Intracranial Meningioma | 06/27 | 08/27 | | |
ESR1814205, NCT04441138: Chemoradiation Followed by Durvalumab in Poor Risk And/or Elderly Patients with Stage III NSCLC |
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| Suspended | 2 | 30 | US | Durvalumab, MEDI4736, imfinzi | Rush University Medical Center, AstraZeneca | Stage III Non-small-cell Lung Cancer | 10/26 | 10/28 | | |