Friedrich-Ebert-Krankenhaus Neumünster
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 1 Trial 
18 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pace, Andrea
ACTION, NCT05580562: ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the Study)

Calendar Jan 2026 - Dec 2026: Final data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Jan 2025 - Mar 2025: Interim data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Recruiting
3
450
Europe, Canada, Japan, US, RoW
Dordaviprone (ONC201), Dordaviprone (ONC201) + Placebo, Placebo
Chimerix
H3 K27M, Glioma
08/26
08/26
NCT04762069 / 2021-003659-40: A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Hourglass Jan 2023 - Jun 2023 : Data from trial for glioblastoma
Hourglass Jul 2022 - Dec 2022 : Interim analysis data from trial for glioblastoma in adults
Active, not recruiting
2
210
Europe, US
Berubicin, Berubicin Hydrochloride, Lomustine, Lomustine Capsules, CCNU, CeeNU, Gleostine
CNS Pharmaceuticals, Inc., Worldwide Clinical Trials
Glioblastoma Multiforme, Adult
02/26
03/26
Siegler, Gabriele
RAMTAS, NCT03520946 / 2017-004162-99: RAMucirumab in Combination Wth TAS102 vs. TAS102 Alone in Chemotherapy Refractory Metastatic Colorectal Cancer Patients

Completed
3
430
Europe
Ramucirumab, TAS 102
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Eli Lilly and Company, Trium Analysis Online GmbH
Colorectal Cancer
07/24
07/24
NeoART, NCT06731803: Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma

Recruiting
1/2
36
Europe
Trastuzumab deruxtecan + 5FU/LV, Trastuzumab deruxtecan + FLO
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Daiichi Sankyo
Esophagogastric Adenocarcinoma
12/27
12/27
Götze, Thorsten
COMPASS, NCT03164980: QoL-Comparison Between Trabectedin/PLD and Pt-based Therapy in Patients With Pt-sensitive Recurrent Ovarian Cancer

Terminated
4
89
Europe
Trabectidin (Yondelis)
North Eastern German Society of Gynaecological Oncology, Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, PharmaMar
Quality of Life, Ovarian Cancer, Recurrent Ovarian Carcinoma
08/23
08/23
NCT04817189 / 2019-004686-41: Oral Akynzeo® Vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)

Completed
4
414
Europe, RoW
NEPA (300mg netupitant/0.5mg palonosetron), Akynzeo® capsules, Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), 5-HT3 RA, Dexamethasone, 8 mg (oral) or equivalent IV dose, corticosteroid
Helsinn Healthcare SA
Chemotherapy-induced Nausea and Vomiting
07/24
07/24
NCT06680622: Bemarituzumab in FGFR2b+ Patients with Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed At Least One Prior Line of Palliative Chemotherapy

Recruiting
2
126
Europe
bemarituzumab, paclitaxel, ramucirumab, bemarituzumab, irinotecan, bemarituzumab, trifluridine/tipiracil
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Amgen, Johannes Gutenberg University Mainz, Technical University of Munich
Metastatic Gastro-esophageal Adenocarcinoma
09/27
03/28
FORTE, NCT05503797 / 2022-000627-20: A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Recruiting
2
250
Europe, Canada, US, RoW
Plixorafenib, FORE8394, PLX8394, Cobicistat, TYBOST(R)
Fore Biotherapeutics, Fore Biotherapeutics
Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors, Melanoma BRAF V600E/K Mutated, Thyroid Cancer
06/26
12/26
EXPAND-1, NCT06470763: A Study Evaluating ANV600 Single Agent or in Combination with Pembrolizumab in Participants with Advanced Solid Tumors

Recruiting
1/2
240
Europe, US
ANV600, ANV600 + pembrolizumab (KEYTRUDA®)
Anaveon AG, Merck Sharp & Dohme LLC
Advanced Solid Tumor
10/27
02/28
NeoART, NCT06731803: Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma

Recruiting
1/2
36
Europe
Trastuzumab deruxtecan + 5FU/LV, Trastuzumab deruxtecan + FLO
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Daiichi Sankyo
Esophagogastric Adenocarcinoma
12/27
12/27
INSIGHT, NCT03252938: Feasibility and Safety of IMP321 (eftilagimod Alpha) for Advanced Stage Solid Tumors

Hourglass Jan 2021 - Dec 2021 : Final data from INSIGHT-004 study in combination with Bavencio for solid tumors
Checkmark Presentation of data from INSIGHT-004 study in combination with Bavencio for advanced solid tumors at ASCO 2021
Jun 2021 - Jun 2021: Presentation of data from INSIGHT-004 study in combination with Bavencio for advanced solid tumors at ASCO 2021
Checkmark Data from INSIGHT 004 study in combination with avelumab for advanced solid tumors at ESMO 2020
Sep 2020 - Sep 2020: Data from INSIGHT 004 study in combination with avelumab for advanced solid tumors at ESMO 2020
More
Recruiting
1
110
Europe
IMP321, LAG-3Ig fusion protein, Avelumab
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Immutep S.A.S.
Solid Tumors, Peritoneal Carcinomatosis, NSCLC Adenocarcinoma, Urothelial Carcinoma
09/25
09/25
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Bajorat, Kristin
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Zimmermann, Paul
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Hamann, Karsten
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Haas, Siegfried
INFINITY, NCT04389541: Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology

Completed
N/A
499
Europe
iOMEDICO AG, Bristol-Myers Squibb, Roche Pharma AG
Advanced Solid Tumors or Hematologic Malignancies
06/23
06/23
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Bankstahl, Ulli
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pace, Andrea
ACTION, NCT05580562: ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the Study)

Calendar Jan 2026 - Dec 2026: Final data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Jan 2025 - Mar 2025: Interim data from ACTION trial for newly diagnosed H3 K27M-mutant diffuse glioma
Recruiting
3
450
Europe, Canada, Japan, US, RoW
Dordaviprone (ONC201), Dordaviprone (ONC201) + Placebo, Placebo
Chimerix
H3 K27M, Glioma
08/26
08/26
NCT04762069 / 2021-003659-40: A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Hourglass Jan 2023 - Jun 2023 : Data from trial for glioblastoma
Hourglass Jul 2022 - Dec 2022 : Interim analysis data from trial for glioblastoma in adults
Active, not recruiting
2
210
Europe, US
Berubicin, Berubicin Hydrochloride, Lomustine, Lomustine Capsules, CCNU, CeeNU, Gleostine
CNS Pharmaceuticals, Inc., Worldwide Clinical Trials
Glioblastoma Multiforme, Adult
02/26
03/26
Siegler, Gabriele
RAMTAS, NCT03520946 / 2017-004162-99: RAMucirumab in Combination Wth TAS102 vs. TAS102 Alone in Chemotherapy Refractory Metastatic Colorectal Cancer Patients

Completed
3
430
Europe
Ramucirumab, TAS 102
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Eli Lilly and Company, Trium Analysis Online GmbH
Colorectal Cancer
07/24
07/24
NeoART, NCT06731803: Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma

Recruiting
1/2
36
Europe
Trastuzumab deruxtecan + 5FU/LV, Trastuzumab deruxtecan + FLO
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Daiichi Sankyo
Esophagogastric Adenocarcinoma
12/27
12/27
Götze, Thorsten
COMPASS, NCT03164980: QoL-Comparison Between Trabectedin/PLD and Pt-based Therapy in Patients With Pt-sensitive Recurrent Ovarian Cancer

Terminated
4
89
Europe
Trabectidin (Yondelis)
North Eastern German Society of Gynaecological Oncology, Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, PharmaMar
Quality of Life, Ovarian Cancer, Recurrent Ovarian Carcinoma
08/23
08/23
NCT04817189 / 2019-004686-41: Oral Akynzeo® Vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)

Completed
4
414
Europe, RoW
NEPA (300mg netupitant/0.5mg palonosetron), Akynzeo® capsules, Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), 5-HT3 RA, Dexamethasone, 8 mg (oral) or equivalent IV dose, corticosteroid
Helsinn Healthcare SA
Chemotherapy-induced Nausea and Vomiting
07/24
07/24
NCT06680622: Bemarituzumab in FGFR2b+ Patients with Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed At Least One Prior Line of Palliative Chemotherapy

Recruiting
2
126
Europe
bemarituzumab, paclitaxel, ramucirumab, bemarituzumab, irinotecan, bemarituzumab, trifluridine/tipiracil
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Amgen, Johannes Gutenberg University Mainz, Technical University of Munich
Metastatic Gastro-esophageal Adenocarcinoma
09/27
03/28
FORTE, NCT05503797 / 2022-000627-20: A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Recruiting
2
250
Europe, Canada, US, RoW
Plixorafenib, FORE8394, PLX8394, Cobicistat, TYBOST(R)
Fore Biotherapeutics, Fore Biotherapeutics
Cancer Harboring BRAF Alterations, HGG, LGG, Solid Tumors, Melanoma BRAF V600E/K Mutated, Thyroid Cancer
06/26
12/26
EXPAND-1, NCT06470763: A Study Evaluating ANV600 Single Agent or in Combination with Pembrolizumab in Participants with Advanced Solid Tumors

Recruiting
1/2
240
Europe, US
ANV600, ANV600 + pembrolizumab (KEYTRUDA®)
Anaveon AG, Merck Sharp & Dohme LLC
Advanced Solid Tumor
10/27
02/28
NeoART, NCT06731803: Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma

Recruiting
1/2
36
Europe
Trastuzumab deruxtecan + 5FU/LV, Trastuzumab deruxtecan + FLO
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Daiichi Sankyo
Esophagogastric Adenocarcinoma
12/27
12/27
INSIGHT, NCT03252938: Feasibility and Safety of IMP321 (eftilagimod Alpha) for Advanced Stage Solid Tumors

Hourglass Jan 2021 - Dec 2021 : Final data from INSIGHT-004 study in combination with Bavencio for solid tumors
Checkmark Presentation of data from INSIGHT-004 study in combination with Bavencio for advanced solid tumors at ASCO 2021
Jun 2021 - Jun 2021: Presentation of data from INSIGHT-004 study in combination with Bavencio for advanced solid tumors at ASCO 2021
Checkmark Data from INSIGHT 004 study in combination with avelumab for advanced solid tumors at ESMO 2020
Sep 2020 - Sep 2020: Data from INSIGHT 004 study in combination with avelumab for advanced solid tumors at ESMO 2020
More
Recruiting
1
110
Europe
IMP321, LAG-3Ig fusion protein, Avelumab
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Immutep S.A.S.
Solid Tumors, Peritoneal Carcinomatosis, NSCLC Adenocarcinoma, Urothelial Carcinoma
09/25
09/25
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Bajorat, Kristin
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Zimmermann, Paul
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Hamann, Karsten
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Haas, Siegfried
INFINITY, NCT04389541: Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology

Completed
N/A
499
Europe
iOMEDICO AG, Bristol-Myers Squibb, Roche Pharma AG
Advanced Solid Tumors or Hematologic Malignancies
06/23
06/23
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24
Bankstahl, Ulli
PLATON, NCT04484636: - Platform for Analyzing Targetable Tumor Mutations (pilot-study)

Completed
N/A
400
Europe
FoundationOne®CDx and FoundationOne®Liquid
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Roche Pharma AG
Hepatocellular Cancer, Cholangiocarcinoma, Gallbladder Cancer, Pancreatic Cancer, Oesophageal Cancer, Stomach Cancer
08/24
12/24

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