GHB Sud- Hôpital de Lorient Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

ARGAUD, Laurent

BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis

Recruiting

600

Europe

continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group

Assistance Publique - Hôpitaux de Paris

Sepsis

12/25

ADAPT, NCT04166331: Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion

Recruiting

270

Europe

Placebos, Dobutamine

University Hospital, Limoges, Centre d'Investigation Clinique 1415

Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction

12/25

IGNORANT, NCT05843786: Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients

Recruiting

132

Europe

Interferon gamma, Placebo

Hospices Civils de Lyon

Pneumonia, Ventilator-Associated

07/25

PEITHO-3, NCT04430569 / 2018-000816-96: Pulmonary Embolism International THrOmbolysis Study-3

Recruiting

650

Europe, Canada, RoW

Alteplase, Placebo

Assistance Publique - Hôpitaux de Paris, Johannes Gutenberg University Mainz, Life Sciences Research Partners (D Collen Research Foundation), Canadian Institutes of Health Research (CIHR), Instituto de Salud Carlos III, International Network of VENous Thromboembolism Clinical Research Networks, Boehringer Ingelheim

Pulmonary Embolism

09/25

08/27

RICO, NCT04392401: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected with SARS-CoV-2: Multicentric Non Interventional Study

Recruiting

N/A

200

Europe

Collection of blood samples in order to create a biocollection

Hospices Civils de Lyon, BioMérieux

Intensive Care Unit, SARS-Cov-2

08/25

CovidEP, NCT04751643: Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections

Recruiting

N/A

132

Europe

Therapeutic plasma exchange : 3 sessions in 3 consecutive days (day 1 to day 3), Usual treatments in intensive care unit according to the current state of knowledge

Hospices Civils de Lyon

Intensive Care Units, ARDS, Human, Covid19

12/22

VT4COVID, NCT04349618: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia

Recruiting

N/A

200

Europe

PROTECTIVE VENTILATION, ULTRAPROTECTIVE VENTILATION

Hospices Civils de Lyon

Acute Respiratory Distress Syndrome, COVID19, Sars-CoV2, Pneumonia

04/23

FAME, NCT05461521: Improving FAMily Members' Experience in the ICU

Completed

N/A

1346

Europe, RoW

Family members of patients admitted to the ICU, Health care professionals, Patients

Nantes University Hospital, Assistance Publique - Hôpitaux de Paris, Assistance Publique Hopitaux De Marseille

Stress Disorders, Post-Traumatic, Family Members

01/24

09/24

Proglegio, NCT03064737: Bacterial and Human Biomarkers of Prognostic Value for Severe Legionnaire's Disease

Recruiting

N/A

300

Europe

Skin biopsy for genetic analyze

Hospices Civils de Lyon

Legionella

01/24

01/25

EXSUPEEP, NCT05147636: EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit

Completed

N/A

425

Europe

Extubation with PEEP, Endotracheal Aspiration

Centre Hospitalier de Bourg en Bresse, Direction Générale de l'Offre de Soins, Hospices Civils de Lyon

Extubation in Intensive Care Unit

03/25

IDBIORIV, NCT06219135: Evaluation of the Performance of the Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis

Recruiting

N/A

1372

Europe

no intervention - Contamination group, blood sample - Bacteraemia group, no intervention - Emergency group

Hospices Civils de Lyon

Sepsis

01/26

05/26

RECO-OHCA, NCT06306625: REmote COnditioning in Out-of-Hospital Cardiac Arrest

Recruiting

N/A

220

Europe

Remote ischemic conditioning, No remote ischemic conditioning

Hospices Civils de Lyon

Out-Of-Hospital Cardiac Arrest

06/26

10/26

NUTRIREA-4, NCT06581939: Impact of an Early and Extended Rehabilitation Program Combining Individually Tailored Nutrition and Physical Activities on Patient Outcomes After Invasive Mechanical Ventilation and Vasopressor Therapy in the ICU

Recruiting

N/A

830

Europe

Rehabilitation group, Control group

Nantes University Hospital

Mechanical Ventilation

06/27

12/27

ADDICT, NCT06738771: Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa

Recruiting

N/A

600

Europe, RoW

Centre Hospitalier Régional d'Orléans

Pseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial, Antibacterial Agents, Beta-lactam Antibiotics

01/27

POSTPONE, NCT06743529: Immediate Versus Substantiated Antibiotic Therapy in Suspected Non-Severe Ventilator-Associated Pneumonia

Not yet recruiting

N/A

686

Europe, RoW

control group, Conservative strategy

Nantes University Hospital

Ventilator-Associated Pneumonia (VAP)

10/28

01/29

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

ARGAUD, Laurent

BICCS, NCT05681442: Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis

Recruiting

600

Europe

continuous pivotal βL-AB, CID group, intermittent pivotal βL-AB, IID control group, AG infusion most 1 dose, AMT group, AG infusion for 5 days, ACT Group

Assistance Publique - Hôpitaux de Paris

Sepsis

12/25

ADAPT, NCT04166331: Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion

Recruiting

270

Europe

Placebos, Dobutamine

University Hospital, Limoges, Centre d'Investigation Clinique 1415

Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction

12/25

IGNORANT, NCT05843786: Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients

Recruiting

132

Europe

Interferon gamma, Placebo

Hospices Civils de Lyon

Pneumonia, Ventilator-Associated

07/25

PEITHO-3, NCT04430569 / 2018-000816-96: Pulmonary Embolism International THrOmbolysis Study-3

Recruiting

650

Europe, Canada, RoW

Alteplase, Placebo

Pulmonary Embolism

09/25

08/27

RICO, NCT04392401: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected with SARS-CoV-2: Multicentric Non Interventional Study

Recruiting

N/A

200

Europe

Collection of blood samples in order to create a biocollection

Hospices Civils de Lyon, BioMérieux

Intensive Care Unit, SARS-Cov-2

08/25

CovidEP, NCT04751643: Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections

Recruiting

N/A

132

Europe

Therapeutic plasma exchange : 3 sessions in 3 consecutive days (day 1 to day 3), Usual treatments in intensive care unit according to the current state of knowledge

Hospices Civils de Lyon

Intensive Care Units, ARDS, Human, Covid19

12/22

VT4COVID, NCT04349618: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia

Recruiting

N/A

200

Europe

PROTECTIVE VENTILATION, ULTRAPROTECTIVE VENTILATION

Hospices Civils de Lyon

Acute Respiratory Distress Syndrome, COVID19, Sars-CoV2, Pneumonia

04/23

FAME, NCT05461521: Improving FAMily Members' Experience in the ICU

Completed

N/A

1346

Europe, RoW

Family members of patients admitted to the ICU, Health care professionals, Patients

Nantes University Hospital, Assistance Publique - Hôpitaux de Paris, Assistance Publique Hopitaux De Marseille

Stress Disorders, Post-Traumatic, Family Members

01/24

09/24

Proglegio, NCT03064737: Bacterial and Human Biomarkers of Prognostic Value for Severe Legionnaire's Disease

Recruiting

N/A

300

Europe

Skin biopsy for genetic analyze

Hospices Civils de Lyon

Legionella

01/24

01/25

EXSUPEEP, NCT05147636: EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit

Completed

N/A

425

Europe

Extubation with PEEP, Endotracheal Aspiration

Centre Hospitalier de Bourg en Bresse, Direction Générale de l'Offre de Soins, Hospices Civils de Lyon

Extubation in Intensive Care Unit

03/25

IDBIORIV, NCT06219135: Evaluation of the Performance of the Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis

Recruiting

N/A

1372

Europe

no intervention - Contamination group, blood sample - Bacteraemia group, no intervention - Emergency group

Hospices Civils de Lyon

Sepsis

01/26

05/26

RECO-OHCA, NCT06306625: REmote COnditioning in Out-of-Hospital Cardiac Arrest

Recruiting

N/A

220

Europe

Remote ischemic conditioning, No remote ischemic conditioning

Hospices Civils de Lyon

Out-Of-Hospital Cardiac Arrest

06/26

10/26

Recruiting

N/A

830

Europe

Rehabilitation group, Control group

Nantes University Hospital

Mechanical Ventilation

06/27

12/27

ADDICT, NCT06738771: Antimicrobial Therapy for Difficult-to-treat Pseudomonas Aeruginosa

Recruiting

N/A

600

Europe, RoW

Centre Hospitalier Régional d'Orléans

Pseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial, Antibacterial Agents, Beta-lactam Antibiotics

01/27

POSTPONE, NCT06743529: Immediate Versus Substantiated Antibiotic Therapy in Suspected Non-Severe Ventilator-Associated Pneumonia

Not yet recruiting

N/A

686

Europe, RoW

control group, Conservative strategy

Nantes University Hospital

Ventilator-Associated Pneumonia (VAP)

10/28

01/29



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