Public Health Laboratory - Ivo de Carneri (PHL-IdC) Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Keiser, Jennifer

TREMO-Pemba, NCT06736691: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole, similar placebo to mebendazole

Swiss Tropical & Public Health Institute, Public Health Laboratory Ivo de Carneri, Bayer, Silicon Valley Community Foundation

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

09/25

11/25

TREMO-Siargao, NCT06800248: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole, matching placebo of emodepside

Swiss Tropical & Public Health Institute, Bayer, Silicon Valley Community Foundation, University of the Philippines

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

12/25

02/26

StrongMoxy, NCT04056325: Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis

Completed

2/3

617

RoW

Moxidectin, Ivermectin, Placebo oral tablet

Jennifer Keiser, National Institute of Public Health, Vientiane, Laos

Strongyloides Stercoralis Infection

04/21

OXA-TRI, NCT06720259: Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura

Completed

163

RoW

Oxantel Pamoate, Mebendazole

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

05/25

HELP-OXA, NCT06606860: Safety, Tolerability and PK of Single and Multiple Doses of Oxantel Pamoate Tablets

Completed

RoW

Oxantel Pamoate, Placebo

Swiss Tropical & Public Health Institute, Ifakara Health Institute, Drugs for Neglected Diseases initiative

Healthy

03/25

FACE-ITpilot, NCT06497075: Co-administration of IVM and ALB in School-based Deworming in Uganda

Completed

N/A

8767

RoW

Albendazole 400mg, Zentel, Ivermectin 3 MG, Mectizan, Stromectol

Jennifer Keiser, Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health, Uganda, Makerere University

Helminthiasis, Intestinal Worms

07/24

10/24

Ali, Said M

Moxiped, NCT06188715: Efficacy and Safety of MOX/ALB Co-administration in SAC

Completed

224

RoW

Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Zentel®, Placebo MOX, Placebo ALB

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuriasis, Ascariasis, Hookworm Infections

08/24

TREMO-Pemba, NCT06736691: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole, similar placebo to mebendazole

Swiss Tropical & Public Health Institute, Public Health Laboratory Ivo de Carneri, Bayer, Silicon Valley Community Foundation

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

09/25

11/25

NCT05538767: Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm

Completed

320

RoW

Emodepside, Albendazole 400mg

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Hookworm Infections

04/23

Iverped, NCT06184399: Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC

Completed

260

RoW

Ivermectin 1.5 mg ODT, Ivermectin 3 mg Oral Tablet, Stromectol®, Albendazole 400 mg Oral Tablet, Zentel®, Placebo IVM ODT

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuriasis, Ascariasis, Hookworm Infections

08/24

OXA-TRI, NCT06720259: Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura

Completed

163

RoW

Oxantel Pamoate, Mebendazole

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

05/25

SchistoBreak-D, NCT06808750: Performance of Tests for Schistosoma Haematobium Diagnosis

Recruiting

N/A

1200

RoW

S. haematobium egg detection by single urine filtration, S. haematobium egg detection by quintuple urine filtration, S. haematobium egg detection by artificial intelligence (AI) microscopy, Haematuria assessment using reagent strips, S. haematobium antigen detection by up-converting reporter particle-lateral flow circulating anodic antigen assay (UCP-LF CAA), S. haematobium DNA detection by recombinase polymerase amplification assay (RPA), S. haematobium DNA detection by qPCR

Stefanie Knopp, Public Health Laboratory Ivo de Carneri, Enaiblers AB, Erasmus Medical Center, Leiden University Medical Center, Natural History Museum, United Kingdom

Schistosoma Haematobium

08/25

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Keiser, Jennifer

TREMO-Pemba, NCT06736691: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole, similar placebo to mebendazole

Swiss Tropical & Public Health Institute, Public Health Laboratory Ivo de Carneri, Bayer, Silicon Valley Community Foundation

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

09/25

11/25

TREMO-Siargao, NCT06800248: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole, matching placebo of emodepside

Swiss Tropical & Public Health Institute, Bayer, Silicon Valley Community Foundation, University of the Philippines

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

12/25

02/26

StrongMoxy, NCT04056325: Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis

Completed

2/3

617

RoW

Moxidectin, Ivermectin, Placebo oral tablet

Jennifer Keiser, National Institute of Public Health, Vientiane, Laos

Strongyloides Stercoralis Infection

04/21

OXA-TRI, NCT06720259: Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura

Completed

163

RoW

Oxantel Pamoate, Mebendazole

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

05/25

HELP-OXA, NCT06606860: Safety, Tolerability and PK of Single and Multiple Doses of Oxantel Pamoate Tablets

Completed

RoW

Oxantel Pamoate, Placebo

Swiss Tropical & Public Health Institute, Ifakara Health Institute, Drugs for Neglected Diseases initiative

Healthy

03/25

FACE-ITpilot, NCT06497075: Co-administration of IVM and ALB in School-based Deworming in Uganda

Completed

N/A

8767

RoW

Albendazole 400mg, Zentel, Ivermectin 3 MG, Mectizan, Stromectol

Jennifer Keiser, Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health, Uganda, Makerere University

Helminthiasis, Intestinal Worms

07/24

10/24

Ali, Said M

Moxiped, NCT06188715: Efficacy and Safety of MOX/ALB Co-administration in SAC

Completed

224

RoW

Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Zentel®, Placebo MOX, Placebo ALB

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuriasis, Ascariasis, Hookworm Infections

08/24

TREMO-Pemba, NCT06736691: Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Not yet recruiting

315

RoW

emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole, similar placebo to mebendazole

Swiss Tropical & Public Health Institute, Public Health Laboratory Ivo de Carneri, Bayer, Silicon Valley Community Foundation

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

09/25

11/25

NCT05538767: Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm

Completed

320

RoW

Emodepside, Albendazole 400mg

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Hookworm Infections

04/23

Iverped, NCT06184399: Efficacy, Safety and Acceptability of Ivermectin ODT in PSAC

Completed

260

RoW

Ivermectin 1.5 mg ODT, Ivermectin 3 mg Oral Tablet, Stromectol®, Albendazole 400 mg Oral Tablet, Zentel®, Placebo IVM ODT

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuriasis, Ascariasis, Hookworm Infections

08/24

OXA-TRI, NCT06720259: Efficacy and Safety of Oxantel Pamoate in Children Infected With Trichuris Trichiura

Completed

163

RoW

Oxantel Pamoate, Mebendazole

Jennifer Keiser, Public Health Laboratory Ivo de Carneri

Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection

05/25

SchistoBreak-D, NCT06808750: Performance of Tests for Schistosoma Haematobium Diagnosis

Recruiting

N/A

1200

RoW

Stefanie Knopp, Public Health Laboratory Ivo de Carneri, Enaiblers AB, Erasmus Medical Center, Leiden University Medical Center, Natural History Museum, United Kingdom

Schistosoma Haematobium

08/25



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