University of Washington Medicine Diabetes Institute (UWMDI)
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 0 Trials 
13 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Bjornstad, Petter
ATTEMPT, NCT04333823: Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial

Active, not recruiting
3
100
Canada, US
Dapagliflozin 5mg, FORXIGA 5mg, ATC Code: A10BK01, DIN: 02435462, Placebo, Placebo (for Dapagliflozin)
The Hospital for Sick Children, Canadian Institutes of Health Research (CIHR), Juvenile Diabetes Research Foundation
Diabetes Mellitus, Type 1
05/24
05/24
SUGARNSALT, NCT06217302: Sotagliflozin to Slow Kidney Function Decline in Persons with Type 1 Diabetes and Diabetic Kidney Disease

Recruiting
3
150
Canada, US
Sotagliflozin, INPEFA, Placebo
Alessandro Doria, Canadian Institutes of Health Research (CIHR), The Kidney Foundation of Canada, The Cleveland Clinic, University of Michigan, University of Colorado, Denver, Northwestern University, Washington University School of Medicine, State University of New York - Upstate Medical University, Providence Medical Research Center, Stanford University, Montefiore Medical Center, University of Toronto, University Health Network, Toronto, University of Calgary, University of Alberta, University of British Columbia, Institut de Recherches Cliniques de Montreal, LMC Diabetes & Endocrinology Ltd., Joslin Diabetes Center, Lexicon Pharmaceuticals, DexCom, Inc., University of Washington, Breakthrough T1D
Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
12/28
05/29
T1-DISCO, NCT05819138: Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes

Recruiting
3
60
US
Semaglutide Pen Injector, Ozempic, Placebo
University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 1
10/26
12/26
NCT05507892: Renal Mechanism of SGLT2 Inhibition

Recruiting
2
40
US
canagliflozin, Invokana, Aminohippurate Sodium Inj 20%, -Sodium 4-amino hippurate (PAH) inj 20% 2g/10mL -Para-aminohippurate
University of Colorado, Denver, Boston Medical Center, University of Michigan, Brigham and Women's Hospital
Type 2 Diabetes, Diabetic Kidney Disease
07/24
07/24
ASPIRE, NCT06072326: Ambrisentan Sotagliflozin and Prevention of Renal Injury; a Randomized Evaluation

Not yet recruiting
2
36
Europe, Canada, US
Sotagliflozin, Ambrisentan, Ambrisentan and Sotagliflozin
University Medical Center Groningen, Juvenile Diabetes Research Foundation, Lexicon Pharmaceuticals
Type 1 Diabetes Mellitus With Diabetic Nephropathy
03/25
03/25
NCT05936151: A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Recruiting
2
120
Europe, Canada, US
Retatrutide, LY3437943, Placebo
Eli Lilly and Company
Overweight or Obesity, CKD, Type 2 Diabetes
11/25
11/25
TREASURE-CKD, NCT05536804 / 2021-005273-47: A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Recruiting
2
140
Europe, Canada, US, RoW
Tirzepatide, Placebo
Eli Lilly and Company, Eli Lilly and Company
Overweight, Obesity, Chronic Kidney Disease, Type 2 Diabetes, T2D
01/26
02/26
RT1D, NCT05822609: Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes

Recruiting
2
60
Canada, US
Semaglutide, Placebo
University of Washington, Juvenile Diabetes Research Foundation, University of Colorado, Denver, Providence Healthcare, University of Toronto
Diabetic Kidney Disease, Type 1 Diabetes
06/26
06/26
NCT03584217: Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study

Active, not recruiting
1/2
100
US
Aminohippurate Sodium Inj 20%, Sodium 4-amino hippurate (PAH) inj 20% 2g/10mL, Para-aminohippurate, Aminohippuric acid, Iohexol Inj 300 MG/ML, omnipaque 300, Renal Biopsy, Kidney Biopsy
University of Colorado, Denver
Type 2 Diabetes Mellitus, Obesity, Nephropathy, Adolescent Obesity
06/23
10/23
IMPROVE-T2D, NCT03620773: Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes

Active, not recruiting
1/2
30
US
Aminohippurate Sodium Inj 20%, Aminohippuric acid, Para-aminohippurate, Sodium 4-amino hippurate (PAH) inj 20% 2g/10 mL, Iohexol Inj 300 mg/mL, omnipaque 300, Vertical Sleeve Gastrectomy, Bariatric Surgery, Renal Biopsy, Kidney Biopsy
University of Colorado, Denver
Type 2 Diabetes Mellitus, Obesity, Bariatric Surgery Candidate, Nephropathy, Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes Complications, Weight Loss, Diabetic Nephropathies, Adolescent Obesity, Pediatric Obesity
10/24
10/24
NCT05008276: Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

Recruiting
N/A
100
US
Aminohippurate Sodium Inj 20%, Sodium 4-amino hippurate (PAH) inj 20% 2g/10mL, Para-aminohippurate, Aminohippuric acid, Iohexol Inj 300 MG/ML, omnipaque 300, Dextran 40, Dextran Sieving
University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Adolescent Obesity, Pre Diabetes, Kidney Hypoxia, Puberty
12/27
12/27
PANDA, NCT05319990: Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The Study)

Recruiting
N/A
100
US
Aminohippurate Sodium Inj 20% Diagnostic aid/agent used to measure effective renal plasma flow (ERPF), Sodium 4-amino hippurate (PAH) inj 20% 2g/10mL, Para-aminohippurate, Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR), omnipaque 300
University of Colorado, Denver, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes, Diabetic Kidney Disease, Diabetes Complications, Diabetic Nephropathies, Autoimmune Diabetes
06/27
12/27
HEIRitage, NCT05530356: Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study

Enrolling by invitation
N/A
100
US
Aminohippurate Sodium Inj 20%, Sodium 4-amino hippurate (PAH) inj 20% 2g/10mL, Para-aminohippurate, Aminohippuric acid, Iohexol Inj 300 MG/ML, omnipaque 300, Dextran 40, Dextran, LMD, Renal Biopsy, Kidney Biopsy, Positron Emission Tomography, PET Scan
University of Colorado, Denver
Type 2 Diabetes, Diabetes Type 2, Diabetic Nephropathies, Nephropathy, Obesity, Adolescent Obesity, Diabetic Kidney Disease
09/27
05/29

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