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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Ungern-Sternberg, Britta Von
POPSICLE, NCT06354699: A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children	Recruiting	N/A	5000	RoW		Telethon Kids Institute	Chronic Pain	06/28	07/28
BIG APPLE, NCT06166706: Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia	Recruiting	N/A	10000	Europe, RoW		Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications	12/25	01/26
NCT05673499: International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery	Recruiting	N/A	900	Europe, US, RoW	NIRS/EEG monitoring	Children's Hospital of Philadelphia, Masimo Corporation	Congenital Disorders, Cerebral Desaturation, Neonatal Surgery	12/27	12/27
CRICKET, NCT05804188: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation	Recruiting	N/A	105000	Europe, Canada, US, RoW	tracheal intubation	Thomas Riva, University of Bern, The Hospital for Sick Children, Boston Children’s Hospital, Istituto Giannina Gaslini	Intubation Complication, Adverse Events	12/25	12/25
OPTIMISE-3, NCT06683599: SEALion: Study on Supplemental Oxygenation Via Nasal Cannula for Young Children During Intubation	Recruiting	N/A	240	Europe, RoW	Apneic oxygenation	Vinícius C Quintão, MD, MSc, PhD, University of Bern, The University of Western Australia	Difficult Airway, Difficult Airway Intubation, Neonate	06/26	12/26
NCT05837936: Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients	Recruiting	N/A	600	US, RoW	Total intravenous anesthesia (TIVA), Sevoflurane initiated intravenous anesthesia (SIIVA)	Wake Forest University Health Sciences	Extubation	03/28	03/28

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Ungern-Sternberg, Britta Von
POPSICLE, NCT06354699: A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children	Recruiting	N/A	5000	RoW		Telethon Kids Institute	Chronic Pain	06/28	07/28
BIG APPLE, NCT06166706: Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia	Recruiting	N/A	10000	Europe, RoW		Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications	12/25	01/26
NCT05673499: International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery	Recruiting	N/A	900	Europe, US, RoW	NIRS/EEG monitoring	Children's Hospital of Philadelphia, Masimo Corporation	Congenital Disorders, Cerebral Desaturation, Neonatal Surgery	12/27	12/27
CRICKET, NCT05804188: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation	Recruiting	N/A	105000	Europe, Canada, US, RoW	tracheal intubation	Thomas Riva, University of Bern, The Hospital for Sick Children, Boston Children’s Hospital, Istituto Giannina Gaslini	Intubation Complication, Adverse Events	12/25	12/25
OPTIMISE-3, NCT06683599: SEALion: Study on Supplemental Oxygenation Via Nasal Cannula for Young Children During Intubation	Recruiting	N/A	240	Europe, RoW	Apneic oxygenation	Vinícius C Quintão, MD, MSc, PhD, University of Bern, The University of Western Australia	Difficult Airway, Difficult Airway Intubation, Neonate	06/26	12/26
NCT05837936: Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients	Recruiting	N/A	600	US, RoW	Total intravenous anesthesia (TIVA), Sevoflurane initiated intravenous anesthesia (SIIVA)	Wake Forest University Health Sciences	Extubation	03/28	03/28