| MULLER, Laurent |
| Recruiting | 3 | 272 | Europe | 56 days of weight-adjusted L-Carnitine treatment, 10 days of intravenous placebo (isotonic saline) | Centre Hospitalier Universitaire de Nīmes | Severe Sepsis, Shock, Septic, Acute Kidney Injury | 05/25 | 05/26 | | |
| Completed | N/A | 100 | Europe | | University Hospital, Clermont-Ferrand, Hôpital Edouard Herriot, Rangueil Hospital, Hospices Civils de Lyon, Hopital Louis Pradel, Hôpital Saint Camille, Hôpital de la Timone, University Hospital, Grenoble, University Hospital, Lille, Saint Antoine University Hospital, University Hospital, Strasbourg, University Hospital, Marseille, Centre Hospitalier Universitaire de Nīmes, CH Aix, CH Martigues, CH Alberville, CH Chambery, Rennes University Hospital, Bichat Hospital | Intensive Care Unit | 11/21 | 12/21 | | |
| Not yet recruiting | N/A | 100 | Europe | Circulatory shock with norepinephrine in ICU | Centre Hospitalier Universitaire de Nīmes | Circulatory Collapse and Shock | 12/22 | 12/22 | | |
HyperBetashock, NCT04748796: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility |
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| Recruiting | N/A | 360 | Europe | echocardiography, Landiolol | Centre Hospitalier Universitaire, Amiens, CH Dieppe, CH Elbeuf, CH Le Havre, Centre Hospitalier de Beauvais, CH Compiègne, CH Laon, University Hospital, Caen, CH Cherbourg, University Hospital, Lille, CH Douai, CH Montreuil, Centre Hospitalier de Roubaix, Centre Hospitalier de Bethune, CH Lomme, Centre Hospitalier de Lens, Tourcoing Hospital, Centre Hospitalier VALENCIENNES, Centre Hospitalier Arras, Hospital Ambroise Paré Paris, University Hospital, Brest, Henri Mondor University Hospital, Hospital Avicenne, University Hospital, Montpellier, CH Calais, Hôpital Edouard Herriot, Centre Hospitalier Universitaire de Nīmes, Groupe Hospitalier Pitié-Salpêtrière | Septic Shock, Tachycardia, Mortality During Septic Shock, Beta-blocker | 02/24 | 03/24 | | |
| Completed | N/A | 120 | Europe | Immunological profiling, Additional 1-year follow-up visit for 30 convalescent patients | Centre Hospitalier Universitaire de Nīmes, Institute of Human Genetics, Montpellier | SARS-CoV-2, Covid-19 | 06/23 | 04/24 | | |
STOPFLUID, NCT06043505: Impact of an Echographic Algorithm on Hemodynamic Optimization in the First 4 Days of Septic Shock Management |
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| Recruiting | N/A | 136 | Europe | Echographic hemodynamic algorithm guiding fluid resuscitation | Centre Hospitalier Universitaire de Nīmes | Shock, Septic, Hemodynamic Instability | 09/24 | 10/24 | | |
NCT05997186: Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction |
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| Recruiting | N/A | 40 | Europe | Surgical reconstruction | University Hospital, Basel, Switzerland | Oral Cavity Defect, Oropharynx Defect | 05/27 | 05/27 | | |
| Cuvillon, Philippe |
NCT03634124: Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs |
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| Completed | 3 | 146 | Europe | Blood test, Doppler ultrasound | Centre Hospitalier Universitaire de Nīmes | Deep Vein Thrombosis, Total Hip Prosthesis, Knee Prosthesis | 02/23 | 10/23 | | |
ANTI_XA, NCT06382584: Impact of Treatment With Oral Anticoagulants of Patients With Fractures of the Upper End of the Femur |
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| Completed | N/A | 610 | Europe | Femoral fracture surgery | Centre Hospitalier Universitaire de Nīmes | Direct Oral Anticoagulants (DOACs), Femoral Fractures, Surgery | 06/23 | 06/23 | | |
TELANESTH, NCT04920604: Anesthetic and Perioperative Risk Assessment Before Programmed Surgery: Anesthetic Teleconsultation Versus Face-to-face Anesthesia Consultation. |
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| Recruiting | N/A | 172 | Europe | Face-to-face anesthesia consultation, Remote anesthesia consultation | Centre Hospitalier Universitaire de Nīmes | Telemedicine, Anesthesia, Consultation, Remote | 02/22 | 02/22 | | |
SMART ANGEL 2, NCT04068584: Evaluation of the Impact of the SMART ANGEL â„¢ Device on Follow-up at Home Following Major or Intermediate Outpatient Surgery |
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| Recruiting | N/A | 1260 | Europe | Smart Angel | Centre Hospitalier Universitaire de NÄ«mes, EVOLUCARE | Ambulatory Surgery | 08/22 | 08/22 | | |
NCT04608968: Pediatric Perioperative Satisfaction Questionnaire |
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| Recruiting | N/A | 600 | Europe | | University Hospital, Montpellier, Clinique Saint Roch, Montpellier, Centre Hospitalier Universitaire de Nīmes, University Hospital, Toulouse, University Hospital, Bordeaux, CHU de Lyon, University Hospital, Grenoble, CHU de Nantes | Perioperative, Children, Satisfaction | 12/26 | 12/26 | | |
| Recruiting | N/A | 300 | Europe | Levobupivacaïne | Centre Hospitalier Universitaire de Nīmes | Analgesia | 12/22 | 12/22 | | |
| Recruiting | N/A | 3000 | Europe | | Centre Hospitalier Universitaire de Nīmes | Anesthesia, Ethics, Narrative, Surgery | 06/24 | 06/24 | | |
| Completed | N/A | 968 | Europe | Robot-assisted urological surgery | Société Française d'Anesthésie et de Réanimation | Robot-assisted Urological Surgery | 07/23 | 07/23 | | |
AoA QUALITY, NCT06111248: Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days |
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| Recruiting | N/A | 1276 | Europe | Training | Centre Hospitalier Universitaire de Nīmes | All Conditions Requiring Non-cardiac Surgery | 06/24 | 06/25 | | |
DEXCOEUR, NCT06082856: Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery |
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| Recruiting | N/A | 594 | Europe | Dexmedetomidine, Sufentanil | Centre Hospitalier Universitaire de Nīmes | Anesthesia, Dexmedetomidine, Hemodynamics, Ambulatory Care | 10/25 | 10/25 | | |
OPTI-TWO, NCT05893030: Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk |
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| Recruiting | N/A | 1132 | Europe | anesthesia guided by sedation and analgesia monitoring, anesthesia performed according only to the clinical judgment of the anesthetist as usual practice | Centre Hospitalier Universitaire de Saint Etienne, Direction Générale de l'Offre de Soins | Sedation and Analgesia Monitoring | 01/27 | 12/27 | | |
ETADOL, NCT05326737: Evaluation of Pain Trajectories After Surgery and Their Potential Relationship With Chronicity at 3 Months |
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| Recruiting | N/A | 5000 | Europe | In hospital pain evaluation, In hospital questionnaires, Telephone contact at 3 months | Centre Hospitalier Universitaire de Nīmes | Surgical Procedures, Operative, Pain, Chronic Pain | 02/24 | 05/24 | | |
| Cayla, Guillaume |
AVATAR, NCT02735902: Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1) |
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| Completed | 4 | 170 | Europe | Vitamin K antagonist or direct oral anticoagulant treatment, Aspirin | Centre Hospitalier Universitaire de Nīmes, Medtronic | Transcatheter Aortic Valve Replacement | 02/23 | 01/24 | | |
MATRIX-2, NCT05955365: Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation |
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| Recruiting | 4 | 3010 | Europe | P2Y12 inhibitor, Aspirin, DOAC | Insel Gruppe AG, University Hospital Bern, Sahajanand Medical Technologies Limited | Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor | 09/26 | 12/26 | | |
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) |
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| Recruiting | 3 | 12500 | Europe, Canada, Japan, US, RoW | Lepodisiran Sodium, LY3819469, Placebo | Eli Lilly and Company | Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a) | 03/29 | 03/29 | | |
AQUATIC, NCT04217447: Assessment of Quitting Versus Using Aspirin Therapy in Patients Treated with Oral Anticoagulation for Atrial Fibrillation or Other Indication with Stabilized Coronary Artery Disease |
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| Terminated | 3 | 874 | Europe | OAC + Aspirin 100mg od, OAC + placebo of Aspirin 100mg od | University Hospital, Brest, Bayer | Coronary Artery Disease | 10/24 | 10/24 | | |
| Completed | N/A | 76 | Europe | Inclusion visit, Nurse consultation, Telephone contact, Coronarography on day 0 | Centre Hospitalier Universitaire de Nīmes | Preoperative Anxiety | 05/22 | 05/22 | | |
READAPT-DISCO, NCT05744947: Modalities And Safety Of Cardiac Rehabilitation In A Population Managed For Spontaneous Hematoma Or Coronary Disruption |
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| Recruiting | N/A | 90 | Europe | Data collection | University Hospital, Bordeaux | Cardiac Rehabilitation Program Following the Management of ACS in Patients Presenting With SCAD | 04/23 | 04/23 | | |
| Recruiting | N/A | 140 | Europe | angioplasty | Institut Mutualiste Montsouris, Abbott | Coronary Artery Calcification, Angioplasty | 12/23 | 12/23 | | |
WARNING KD, NCT05033652: Impact on Mortality of Screening for Kidney Disease Associated With a Specialized Intervention During Hospitalization in a Territorial Hospital Trust |
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| Recruiting | N/A | 1680 | Europe | WARNING KD | Centre Hospitalier Universitaire de NÄ«mes | Acute Kidney Injury, Chronic Kidney Diseases | 12/23 | 12/24 | | |
ICARE, NCT05394649: Intravascular Lithotripsy in Comparison to Rotational Atherectomy: An Evaluation by OFDI |
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| Recruiting | N/A | 178 | Europe | Intravascular Lithotripsy, Rotational Atherectomy | University Hospital, Clermont-Ferrand, Clinique Pasteur Toulouse | Intravascular Lithotripsy; Rotational Atherectomy; OFDI | 05/24 | 05/25 | | |
CARDIOMEMS, NCT05428631: Tolerability and Safety of ™ Intracardiac Continuous Cardiac Hemodynamic Monitoring Device in Patients with Cardio Renal Syndrome with Severe Renal Impairment |
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| Recruiting | N/A | 10 | Europe | Implantation of the CARDIOMEMS™ HF device, Nephrolocical evaluation measured with the CARDIOMEMS™ HF device | Centre Hospitalier Universitaire de Nīmes, CHU Arnaud de Villeneuve MONTPELLIER | Heart Failure, Renal Insufficiency | 08/26 | 08/27 | | |
| Active, not recruiting | N/A | 3326 | Europe, RoW | SELUTION SLR, DES | M.A. Med Alliance S.A. | Coronary Artery Disease | 08/25 | 07/30 | | |
| Completed | N/A | 218 | Europe | TAVR | University Hospital, Montpellier | Stenoses, Aortic | 03/24 | 03/24 | | |
BEST, NCT05454150: Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis |
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| Recruiting | N/A | 1862 | Europe | balloon-expandable valve, self-expanding valve | University Hospital, Lille, Ministry of Health, France | Aortic Valve Stenosis | 07/25 | 07/25 | | |
