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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Forbes, Lisa
NCT03512314 / 2018-003199-10: Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency as Open Label Extension	Active, not recruiting	3	10	Europe, Canada, US	Tadekinig alfa, r-hIL-18BP	AB2 Bio Ltd., AB2 Bio Ltd.	XIAP Deficiency, NLRC4-MAS	09/24	10/24
Forbes-Satter, Lisa
NCT03113760 / 2018-003297-27: Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency	Completed	3	15	Europe, Canada, US	Tadekinig alfa, IL-18BP, r-hIL-18BP, 0.9% sodium chloride	AB2 Bio Ltd.	NLRC4-MAS, XIAP Deficiency	10/23	11/23
NCT05693129: Pediatric Patients Aged 1 to 6 Years with APDS	Recruiting	3	15	Europe, Japan, US	Leniolisib	Pharming Technologies B.V., CMIC Co, Ltd. Japan, Labcorp Central Laboratory, Fortrea, Aixial Group	APDS	09/25	02/26