Echaniz-Laguna, Andoni |
NIMBLE, NCT05070858 / 2020-003272-41: A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis |
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| Recruiting | 3 | 235 | Europe, Canada, Japan, US, RoW | Pozelimab + Cemdisiran, Cemdisiran, ALN-CC5, Placebo, Pozelimab, REGN3918 | Regeneron Pharmaceuticals | Generalized Myasthenia Gravis | 05/25 | 03/28 | | |
THERAMAG, NCT05136976: Rituximab Therapy in Anti-Myelin Associated Glycoprotein Patients With Characteristics of Good Responders |
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| Recruiting | 3 | 90 | Europe | Rituximab infusion, Mabthera, Placebo infusion, Sodium chloride (NaCl), Premedications | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Anti-MAG Neuropathy | 12/25 | 12/25 | | |
| Completed | 2 | 30 | Europe | Imlifidase, Hansa Medical-Immunoglobulin G degrading enzyme of Streptococcus pyogenes (HMED-IdeS), IdeS, IgG endopeptidase | Hansa Biopharma AB, Hansa Biopharma AB | Guillain-Barré Syndrome (GBS) | 02/24 | 02/24 | | |
| Terminated | N/A | 10 | Europe | Necrotizing Vasculitis | Lille Catholic University, UNEOS | Necrotizing Vasculitis, Neuropathy | 10/22 | 10/22 | | |
| Recruiting | N/A | 150 | Europe, Canada, Japan, US, RoW | | argenx | Multifocal Motor Neuropathy | 11/25 | 11/25 | | |
Bresch, Saskia |
NCT06298552: A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients with Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis |
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| Recruiting | 3 | 110 | Europe, Canada, US, RoW | Efgartigimod IV, Placebo IV | argenx | Generalized Myasthenia Gravis | 07/25 | 07/27 | | |
NIMBLE, NCT05070858 / 2020-003272-41: A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis |
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| Recruiting | 3 | 235 | Europe, Canada, Japan, US, RoW | Pozelimab + Cemdisiran, Cemdisiran, ALN-CC5, Placebo, Pozelimab, REGN3918 | Regeneron Pharmaceuticals | Generalized Myasthenia Gravis | 05/25 | 03/28 | | |