The Steadman Clinic
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 14 Trials 
39 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Evans, Thomas
SURPASS-2, NCT04752358 / 2020-005802-24: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers

Terminated
2
3
Europe, Canada, US
Autologous genetically modified ADP-A2M4CD8 cells
Adaptimmune, ICON plc
Esophageal Cancer, Esophagogastric Junction Cancer
06/23
12/23
NCT04210986: Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial

Completed
1/2
75
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Placebo oral capsule, Inactive drug
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
01/23
02/23
ST101-101, NCT04478279 / 2019-004213-13: A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

Active, not recruiting
1/2
125
Europe, US
ST101, Temozolomide, Radiation
Sapience Therapeutics
Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer, Glioblastoma Multiforme, GBM, Brain Cancer, Metastatic Breast Cancer, Metastatic Melanoma, Metastatic Prostate Cancer, Melanoma Recurrent, Prostate Cancer Metastatic, Recurrent Glioblastoma, Newly Diagnosed Glioblastoma
12/24
12/25
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
BT7480-100, NCT05163041: Study in Patients With Advanced Malignancies Associated With Nectin-4 Expression

Active, not recruiting
1/2
200
Europe, US
BT7480, Nivolumab
BicycleTx Limited
Advanced Solid Tumor
09/25
12/25
Kim, Raymond J
NCT06108063: Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Recruiting
1/2
120
US
Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Tablet
Steadman Philippon Research Institute
Knee Arthroplasty, Total
06/27
06/27
CHARM, NCT04261972: Cell-free DNA in Hereditary And High-Risk Malignancies

Active, not recruiting
N/A
1416
Canada
Next generation sequencing (NGS)
University Health Network, Toronto, Sinai Health System, Women's College Hospital, Jewish General Hospital, IWK Health Centre, Eastern Health, BC Cancer
Hereditary Cancer Syndrome
12/24
12/24
NCT04725565: Genetics Adviser: Evaluating a Digital Decision Support Tool for Genetic Results

Completed
N/A
133
Canada
Genetics ADvISER Decision Aid Plus Standard Genetic Counselling, Standard Genetic Counseling
Unity Health Toronto
Cancer
04/23
04/24
INSIGHT, NCT03857594: Integrative Sequencing in Germline and Hereditary Tumours

Active, not recruiting
N/A
10
Canada
University Health Network, Toronto
Hereditary Cancer Syndrome, High-Risk, Mutation, Germline Mutation
09/25
09/25
PATHFINDER 2, NCT05155605: a Multi-Cancer Early Detection Study

Active, not recruiting
N/A
35885
Canada, US
Multi-Cancer Early Detection Test
GRAIL, Inc.
Early Detection of Cancer, Cancer
02/26
04/28
CHARM2, NCT06726642: CfDNA in Hereditary And High-risk Malignancies 2

Recruiting
N/A
1000
Canada
Cell-free DNA analysis
University Health Network, Toronto, British Columbia Cancer Agency, Eastern Health, IWK Health Centre, Jewish General Hospital, Sinai Health System, The Hospital for Sick Children
Hereditary Cancer Syndrome
12/29
12/31
NCT01745237: Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

Recruiting
N/A
27000
US
Duke University
Sarcoidosis
06/32
06/32
Tashman, Scott
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
NCT06108063: Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Recruiting
1/2
120
US
Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Tablet
Steadman Philippon Research Institute
Knee Arthroplasty, Total
06/27
06/27
Vidal, Armando F
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
Laprade, Robert
NCT05088525: Meniscal Root Tears: Evaluation Using an Ultrahigh MRI

Completed
N/A
27
US
MRI
Twin Cities Orthopedics
Knee Injuries
11/24
11/24
NCT05073276: Non- Vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction

Recruiting
N/A
50
US
Physical Therapy
Twin Cities Orthopedics
Knee Injuries
01/26
01/26
NCT05073263: Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction

Recruiting
N/A
50
US
Physical Therapy
Twin Cities Orthopedics
Knee Injuries
01/26
01/26
Evans, Thos
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
Whitney, Kaitie
NCT02090140: Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

Recruiting
N/A
17
US
ADSC Application, Microfracture
University of Colorado, Denver, University of Kentucky, Stanford University
Degenerative Lesion of Articular Cartilage of Knee
12/25
12/25
Ebinu, Julius
NCT03118505: A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions

Active, not recruiting
N/A
100
US
Infuse Bone Graft, Medtronic DBM
Medtronic Spinal and Biologics
Multi-Level Degenerative Lumbosacral Spinal Conditions
04/26
12/26
Millett, Peter
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
Provencher, Matthew
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
OASIS, NCT04809064: Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the Trial

Recruiting
N/A
400
US
Arthroscopic Bankart repair procedure, Open Bankart, Latarjet, Post-Operative Rehabilitation
University of Pittsburgh, Walter Reed National Military Medical Center
Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
09/27
09/27
Hackett, Thomas
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
Vidal, Leslie
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
Godin, Jon
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
Philippon, Marc J
NCT05025956: Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

Active, not recruiting
1/2
68
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Placebo, Placebo Oral Capsule
Steadman Philippon Research Institute, United States Department of Defense
Femoroacetabular Impingement
10/24
10/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
Page, Suzanne L
NCT04205656: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

Active, not recruiting
1/2
45
US
Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC), Control group (Placebo)
Steadman Philippon Research Institute, United States Department of Defense, Office of Naval Research (ONR)
Osteoarthritis, Knee
07/24
09/24
NCT05025956: Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

Active, not recruiting
1/2
68
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Placebo, Placebo Oral Capsule
Steadman Philippon Research Institute, United States Department of Defense
Femoroacetabular Impingement
10/24
10/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
NCT06108063: Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Recruiting
1/2
120
US
Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Tablet
Steadman Philippon Research Institute
Knee Arthroplasty, Total
06/27
06/27
Huard, Johnny
NCT05025956: Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan

Active, not recruiting
1/2
68
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Placebo, Placebo Oral Capsule
Steadman Philippon Research Institute, United States Department of Defense
Femoroacetabular Impingement
10/24
10/24
RMIP, NCT04815902: Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis

Active, not recruiting
1/2
100
US
Fisetin, Novusetin, 7,3',4'-flavon-3-ol, 3,3',4',7-tetrahydroxyflavone, Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Capsule, Placebo Fisetin
Steadman Philippon Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Osteoarthritis, Knee
02/25
06/25
NCT06108063: Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Recruiting
1/2
120
US
Losartan, Losartan potassium, Placebo - Losartan, Placebo Oral Tablet
Steadman Philippon Research Institute
Knee Arthroplasty, Total
06/27
06/27

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