| Krumholz, Harlan M |
PAXLC, NCT05668091: A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults with Long COVID. |
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| Completed | 2 | 100 | US | Nirmatrelvir, Ritonavir, Placebo, sugar pill | Harlan M Krumholz, Pfizer | Long COVID | 04/24 | 08/24 | | |
| Active, not recruiting | N/A | 100 | US | No intervention | Yale University, Food and Drug Administration (FDA) | Covid19 Sequelae | 06/23 | 05/25 | | |
| Li, Jing |
BRAVO, NCT05647915: Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals with Obesity and NAFLD |
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| Completed | 4 | 337 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | Obesity, Obesity, Abdominal, NAFLD | 08/24 | 08/24 | | |
NCT06425120: Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease |
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| Not yet recruiting | 4 | 240 | RoW | Xuesaitong Soft Capsule, LixuwangⓇ, Placebo | China National Center for Cardiovascular Diseases | Coronary Heart Disease | 12/24 | 12/24 | | |
NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) |
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| Active, not recruiting | 4 | 8250 | RoW | Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy | Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases | 04/25 | 04/25 | | |
NCT05965284: Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM) |
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| Recruiting | 4 | 40 | RoW | Azathioprine, Telitacicept, Taiai for commercial name | Chinese SLE Treatment And Research Group | ANCA-associated Vasculitis, Maintenance Therapy | 12/25 | 12/26 | | |
ABCD, NCT05749874: Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus |
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| Not yet recruiting | 4 | 6500 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias | 12/26 | 12/26 | | |
NCT05962840: Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) |
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| Recruiting | 4 | 40 | RoW | Telitacicept, Taiai for commercial name, Placebo of Telitacicept | Chinese SLE Treatment And Research Group, Peking Union Medical College Hospital | ANCA Associated Vasculitis | 12/26 | 12/26 | | |
EHTASEOCCS, NCT03373058: Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery |
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| Recruiting | 3 | 310 | RoW | Hyperthermic Intraperitoneal Chemotherapy, HIPEC, cytoreductive surgery, CRS, adjuvant chemotherapy, ACT | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Henan Provincial People's Hospital, Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Peking University Cancer Hospital & Institute, Peking University People's Hospital, Cancer Hospital of Guizhou Province, Chinese PLA General Hospital, Hebei Medical University Fourth Hospital, The Second Hospital of Hebei Medical University, West China Second University Hospital, Peking Union Medical College Hospital, First Affiliated Hospital, Sun Yat-Sen University, Henan Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, The Third Affiliated Hospital of Guangzhou Medical University, Wuhan University, RenJi Hospital, Obstetrics & Gynecology Hospital of Fudan University, Southern Medical University, China, Fourth Affiliated Hospital of Guangxi Medical University, Shandong Cancer Hospital and Institute, Beijing Obstetrics and Gynecology Hospital, Chongqing University Cancer Hospital, Xinqiao Hospital of Chongqing, Wuhan Union Hospital, China, First Affiliated Hospital of Chongqing Medical University, Affiliated Cancer Hospital of Shantou University Medical College | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma | 07/21 | 07/23 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
SHINY, NCT06157502: Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Shuxuening Injection, Placebo | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 06/25 | 12/26 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
Be-CLEVER, NCT05976152: Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial |
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| Recruiting | 3 | 3200 | RoW | dl-3-butylphthalide, DL-3-n-butylphthalide (NBP), dl-3-butylphthalide placebo, NBP placebo | Fudan University | Stroke, Post-stroke Cognitive Impairment (PSCI) | 12/26 | 12/26 | | |
NCT01592968: Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases |
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| Active, not recruiting | 3 | 88 | US | Cognitive Assessment, Quality-of-Life Assessment, Quality of Life Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Malignant Neoplasm, Metastatic Malignant Neoplasm in the Brain | 09/25 | 09/25 | | |
NHIPEC, NCT05246020: Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the Trial) |
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| Recruiting | 2 | 80 | RoW | HIPEC, intravenous chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Hyperthermic Intraperitoneal Chemotherapy, Neoadjuvant Chemotherapy | 12/22 | 12/24 | | |
NCT02713269: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients with Spine Metastases At Risk for Compressing the Spinal Cord |
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| Active, not recruiting | 2 | 60 | US | Computed Tomography, CAT, CAT Scan, Computerized Axial Tomography, computerized tomography, CT, CT SCAN, tomography, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Thermal Ablation Therapy, thermal ablation | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC V6 and V7, Stage IV Lung Non-Small Cell Cancer AJCC V7, Thyroid Gland Carcinoma | 08/25 | 08/25 | | |
NCT06205927: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer |
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| Recruiting | 2 | 77 | RoW | Standard carbon ion beam radiotherapy, Carbon ion beam radiotherapy simultaneously dose boost | Jian Chen | Non-small Cell Lung Cancer | 12/24 | 12/26 | | |
NCT06206278: Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma |
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| Terminated | 2 | 6 | RoW | Infigratinib, BGJ398, BBP-831 | LianBio LLC | Gastric Cancer, Gastroesophageal Junction Adenocarcinoma | 05/24 | 05/24 | | |
NCT06186726: Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors |
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| Recruiting | 2 | 48 | RoW | carbon ion radiotherapy | Jian Chen | Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy | 12/26 | 12/29 | | |
NCT06311981: Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients |
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| Recruiting | 2 | 29 | RoW | carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy | Jian Chen | Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect | 06/25 | 06/26 | | |
NCT06311955: Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor |
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| Recruiting | 2 | 48 | RoW | Carbon ion radiotherapy, combined with platinum-based regimen | Jian Chen | Thymic Epithelial Tumor, Radiotherapy Side Effect, Carbon Ion Radiotheray, Heavy Ion Radiotherapy | 02/28 | 02/29 | | |
NCT06311968: The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor |
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| Recruiting | 2 | 55 | RoW | Proton radiotherapy, combined platinum based chemotherapy | Jian Chen | Thymus Epithelial Tumor, Proton Radiotherapy, Radiation Toxicity | 02/27 | 02/27 | | |
| Not yet recruiting | 2 | 120 | RoW | Metformin Hydrochloride tablet, Metformin, Placebo | Xuanwu Hospital, Beijing, Institute of Zoology, Chinese Academy of Sciences, Beijing Institute of Genomics, Chinese Academy of Sciences, Merck Serono Co., Ltd., China | Metformin, Aging | 09/26 | 07/28 | | |
| Active, not recruiting | 2 | 49 | US | Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Clinical Stage IV Cutaneous Melanoma AJCC V8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC V8 | 08/26 | 08/26 | | |
NCT05593575: Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease |
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| Recruiting | 2 | 320 | RoW | SPH3127+SPH3127matching placebo+valsartan matching placebo, SPH3127+valsartan matching placebo, SPH3127 matching placebo+valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Diabetic Kidney Disease | 06/25 | 06/25 | | |
NCT04516070: Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis |
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| Active, not recruiting | 2 | 55 | US | Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8 | 12/26 | 12/26 | | |
NCT05613452: Carbon Ion Therapy for Peripheral Non-small Cell Lung Cancer |
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| Recruiting | 2 | 43 | RoW | Carbon ion beam radiotherapy | Shanghai Proton and Heavy Ion Center | Non-small Cell Lung Cancer | 01/25 | 01/26 | | |
NCT06036966: The Efficacy and Safety of Hetrombopag in Primary Prevention of Thrombocytopenia Induced by the Niraparib Maintenance in Advanced Ovarian Cancer Patients |
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| Not yet recruiting | 2 | 34 | NA | Hetrombopag | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Thrombocytopenia | 07/25 | 07/25 | | |
FRUSICA-1, NCT03903705: : A Phase Ib/II Study To Evaluate Fruquintinib Monotherapy Or Plus Sintilimab In Advanced Solid Tumors |
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| Recruiting | 1/2 | 381 | RoW | Fruquintinib in Combination with Sintilimab, Fruquintinib | Hutchmed | Advanced Solid Tumor | 12/25 | 12/25 | | |
| Recruiting | 1/2 | 180 | RoW | MG-K10, Placebo | Shanghai Mabgeek Biotech.Co.Ltd | Asthma | 12/23 | 06/24 | | |
NCI-2016-00661, NCT02696993: Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer |
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| Active, not recruiting | 1/2 | 80 | US | Cognitive Assessment, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS-734016, MDX-010, MDX-CTLA4, Yervoy, Laboratory Biomarker Analysis, Nivolumab, BMS-936558, MDX-1106, NIVO, ONO-4538, Opdivo, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | M.D. Anderson Cancer Center | Metastatic Malignant Neoplasm in the Brain, Stage IV Non-Small Cell Lung Cancer AJCC v7 | 12/24 | 12/24 | | |
NCT04592458: Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients |
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| Not yet recruiting | 1 | 10 | RoW | β-globin restored autologous HSC | BGI-research, Shenzhen Children's Hospital | β-Thalassemia Major | 11/22 | 11/24 | | |
| Recruiting | N/A | 100 | RoW | Automated peritoneal dialysis, Intermittent hemodialysis | Limeng Chen, First Hospital of China Medical University, First Affiliated Hospital Xi'an Jiaotong University, Beijing Anzhen Hospital, Xiangya Hospital of Central South University, Baxter Healthcare Corporation | Acute Kidney Injury | 12/22 | 12/22 | | |
NCT04682795: Comparison of Safety and Efficacy of Needle-Free Injector and Insulin Pen in Patients With T2DM |
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| Recruiting | N/A | 200 | RoW | Needle-free injector, Insulin pen | Second Affiliated Hospital, School of Medicine, Zhejiang University | T2DM (Type 2 Diabetes Mellitus), Needle-free Injector, Time in Range | 12/22 | 12/22 | | |
ESPRIT, NCT04030234: Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs () Study |
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| Completed | N/A | 11255 | RoW | Intensive BP treatment group, Control of SBP to <120 mmHg, Standard BP treatment group, Control of SBP to <140 mmHg | China National Center for Cardiovascular Diseases | Hypertension | 06/23 | 07/23 | | |
NCT05352633: Effects of Intensive Systolic Blood Pressure Lowering Treatment on Out-of-office Blood Pressure - an Ancillary Study to Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study |
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| Not yet recruiting | N/A | 710 | RoW | Intensive BP Arm, Control of SBP to <120 mmHg, Standard BP Arm, Control of SBP to <140 mmHg | China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, People's Republic of China | Blood Pressure | 09/23 | 09/23 | | |
PERFECT, NCT06181552: Development of CV Risk Prediction Tools Based on AI and Fundus Imaging Technology Study |
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| Not yet recruiting | N/A | 1072 | NA | fundus photograpgy, optical coherence tomography, OCT, optical coherence tomography angiography, OCT-A | China National Center for Cardiovascular Diseases, Beijing Tongren Hospital | Cardiovascular Diseases | 03/25 | 06/25 | | |
FUTURE, NCT05459519: Effects of Dengzhanxixin Capsule on Platelet Function in Individuals at High Risk for Cardiovascular Disease |
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| Recruiting | N/A | 165 | RoW | Dengzhanxixin Capsule plus Placebo Capsule, Placebo | China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medial Sciences, Shenzhen, Shenzhen | Diabetes, Hypertension, Hypercholesterolemia | 12/23 | 12/23 | | |
NCT05722275: Prediction of Peritoneal Metastasis for Gastric Cancer Based on Radiomics |
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| Recruiting | N/A | 400 | Europe, RoW | Peritoneal metastasis status ascertainment | Chinese Academy of Sciences, Peking University Cancer Hospital & Institute, Zhenjiang First People's Hospital, The First Affiliated Hospital of Zhengzhou University, Nanfang Hospital of Southern Medical University, Guizhou Provincial People's Hospital, Henan Cancer Hospital, Yunnan Cancer Hospital, Guangdong Provincial People's Hospital, Guangzhou Medical University, Fujian Medical University Union Hospital, Shanxi Province Cancer Hospital, Sun Yat-sen University, Beihang University, Scientific Institute San Raffaele | Gastric Cancer, Peritoneal Metastases | 12/23 | 12/28 | | |
NCT06422052: Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms |
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| Recruiting | N/A | 2242 | RoW | Epidemiological questionnaire and Functional Dyspepsia Symptom Diary（FDSD） | Shanghai Jiao Tong University School of Medicine | Helicobacter Pylori Infection, Dyspepsia | 05/25 | 05/25 | | |
NutriConnect, NCT06263751: Comparing the Effectiveness of Two Produce Prescription Approaches On Fruit and Vegetable Intake and Food Security, While Exploring Implementation Outcomes Such as Reach, Implementation, Sustainability, and Cost |
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| Recruiting | N/A | 240 | US | Product prescription program- NutriConnect Credit, Product prescription program- NutriConnect Delivery | Washington University School of Medicine, Schnuck Markets, Inc., BJC HealthCare | Food Insecurity | 03/25 | 06/25 | | |
NCT06163092: Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage |
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| Not yet recruiting | N/A | 175 | RoW | | Chinese University of Hong Kong | Recurrent Miscarriage | 01/26 | 01/27 | | |
NCT05783986: Developing a MRI-based Deep Learning Model to Predict MMR Status |
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| Not yet recruiting | N/A | 600 | NA | randomly divided | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sun Yat-sen University | Endometrial Cancer | 06/24 | 12/24 | | |
NCT06622798: Exploratory Study on the Correlation Between HRD Score and PARPi Efficacy Based on Chinese Ovarian Cancer Patients |
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| Recruiting | N/A | 470 | RoW | Non-interventional | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Amoy Diagnostics Co., LTD | Exploring the Correlation of HRD Score Pairs with the Prognosis of Chinese Ovarian Cancer Patients and the Outcome of Maintenance Therapy with PARPi | 01/25 | 07/26 | | |
NCT06035250: AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy |
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| Recruiting | N/A | 200 | Europe, RoW | Neoadjuvant Chemotherapy | Chinese Academy of Sciences, Peking University Cancer Hospital & Institute, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Yunnan Cancer Hospital, Henan Cancer Hospital, Zhenjiang First People's Hospital, First Hospital of China Medical University, Cancer Hospital of Guangxi Medical University, Peking University People's Hospital, Tianjin Medical University Cancer Institute and Hospital, The First Affiliated Hospital of Zhengzhou University, Nanfang Hospital, Southern Medical University, The Affiliated Hospital of Qingdao University, Ruijin Hospital, Sixth Affiliated Hospital, Sun Yat-sen University, Peking Union Medical College Hospital, Xiangya Hospital of Central South University, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, The First Affiliated Hospital of Soochow University, First Affiliated Hospital, Sun Yat-Sen University, Fujian Medical University Union Hospital, Fujian Cancer Hospital, San Raffaele University Hospital, Italy | Gastric Cancer, Image, Pathology | 08/24 | 12/29 | | |
| Recruiting | N/A | 216 | RoW | Baduanjin, Brisk walking | China National Center for Cardiovascular Diseases | Elevated Blood Pressure | 12/24 | 12/25 | | |
NCT05570071: A Study of the Use of Vaginal Radiofrequency Therapy in Treatment of SUI. |
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| Not yet recruiting | N/A | 90 | NA | physical therapy | Qianfoshan Hospital | Urinary Incontinence, Stress | 03/25 | 03/25 | | |
NCT06025045: Dynamic Monitoring of ctDNA Predicts Recurrence of Advanced Ovarian Cancer After Primary Treatments |
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| Recruiting | N/A | 50 | RoW | | Jing Li, Nanjing Shihejiyin Technology, Inc. | Ovarian Cancer Stage IV, Ovarian Cancer Stage III | 08/25 | 08/25 | | |
CHAPERONE, NCT05965115: The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The Study |
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| Recruiting | N/A | 10000 | RoW | Sample of Blood | Shanghai Zhongshan Hospital | Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance | 08/25 | 08/35 | | |
NCT05613049: Confounding Factors of Chronic Endometritis in Women With Reproductive Failure |
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| Recruiting | N/A | 720 | RoW | | Chinese University of Hong Kong | IVF | 07/27 | 01/28 | | |
NCT05153603: Outcomes of First-line Olaparib Mono-maintenance therapy-a Multicenter, Retrospective Study Using Data From Real-world Clinical Setting |
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| Not yet recruiting | N/A | 50 | NA | Olaparib mono-maintenance therapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Ovarian Neoplasms | 09/22 | 12/22 | | |
| Not yet recruiting | N/A | 300 | NA | Neonatal hyperbilirubinemia | Shanghai First Maternity and Infant Hospital | Jaundice, Neonatal | 09/22 | 09/22 | | |
| Tran, Albert |
| Completed | 3 | 407 | Europe, Canada, US, RoW | Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir | Eiger BioPharmaceuticals | Hepatitis Delta Virus | 10/22 | 03/23 | | |
| Completed | 3 | 410 | Europe, Canada, US, RoW | Albutein 20% Injectable Solution, Standard medical treatment | Grifols Therapeutics LLC, Instituto Grifols, S.A. | Decompensated Cirrhosis and Ascites | 05/24 | 05/24 | | |
NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( ) |
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| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | IVA337, Lanifibranor, Placebo | Inventiva Pharma | NASH - Nonalcoholic Steatohepatitis | 09/25 | 09/26 | | |
| Chen, Pei |
NCT06561698: High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection |
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| Recruiting | 4 | 200 | RoW | Vonoprazan, Amoxicillin, Bismuth Potassium Citrate, Minocycline,Metronidazole | Shanghai Jiao Tong University School of Medicine | Helicobacter Pylori Infection | 08/26 | 08/26 | | |
NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( ) |
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| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | IVA337, Lanifibranor, Placebo | Inventiva Pharma | NASH - Nonalcoholic Steatohepatitis | 09/25 | 09/26 | | |
| wu, bin yu |
NCT03784222: Effects on Social and Cognition Functions of Blonanserin in First Episode Schizophrenia Patients |
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| Terminated | 4 | 102 | RoW | Blonanserin, MRI and serum BDNF | Sumitomo Pharma (Suzhou) Co., Ltd. | First Episode Schizophrenia, Social Function, Cognition Function, Blonanserin | 11/22 | 11/22 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT04937387: Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled Asthma |
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| Completed | 3 | 359 | RoW | FF/VI, FF/UMEC/VI, ELLIPTA | GlaxoSmithKline | Asthma | 08/24 | 08/24 | | |
NCT05837897: A Study of Vedolizumab in Adult Participants With Moderate to Severe Crohn's Disease |
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| Recruiting | 3 | 408 | RoW | Vedolizumab IV, Placebo | Takeda | Crohn's Disease | 03/30 | 05/31 | | |
NCT04825860: A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase |
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| Terminated | 2/3 | 83 | Japan, RoW | SEP-363856 50 mg, SEP-363856 75 mg, Placebo | Sumitomo Pharma Co., Ltd. | Schizophrenia | 10/23 | 10/23 | | |
NCT05292196: A Phase II Clinical Trial of TQC3721 Suspension for Inhalation |
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| Recruiting | 2 | 460 | RoW | TQC3721 suspension for inhalation, TQC3721 suspension placebo for inhalation | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Obstructive Pulmonary Disease (COPD) | 01/24 | 05/24 | | |
NCT05987371: A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease. |
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| Recruiting | 2 | 72 | RoW | TQC3721 suspension for inhalation, TQC3721 matching placebo for inhalation, Salbutamol sulfate inhalation aerosol | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Obstructive Pulmonary Disease | 01/24 | 03/24 | | |
NCT05405439: To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer |
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| Terminated | 1/2 | 39 | RoW | TQB3823 tablets, Abiraterone acetate tablets, prednisone acetate tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Metastatic Castration-resistant Prostate Cancer | 07/23 | 07/23 | | |
NCT05024214: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors |
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| Recruiting | 1/2 | 170 | RoW | Lenvatinib + Envafolimab, Sunitinib | 3D Medicines (Sichuan) Co., Ltd. | Solid Tumors, Non-small Cell Lung Cancer, Renal Cell Carcinoma, Hepatocellular Carcinoma | 12/24 | 12/24 | | |
| Recruiting | 1/2 | 380 | RoW | PM8002 | Biotheus Inc. | Malignant Neoplasm | 11/25 | 11/25 | | |
| Completed | N/A | 400 | RoW | | Third Affiliated Hospital, Sun Yat-Sen University, National Natural Science Foundation of China | Liver Cirrhosis | 12/22 | 10/23 | | |
NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China |
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| Completed | N/A | 1507 | RoW | Prospective observational cohort study | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 11/22 | 02/23 | | |
NCT03641391: Awake Intraoperative Language Mapping and Chinese Probabilistic Map Construction |
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| Not yet recruiting | N/A | 300 | RoW | Intraoperative direct cortical electrical stimulation, Intraoperative direct subcortical electrical stimulation | Huashan Hospital, Shanghai Zhongshan Hospital, Huashan Hospital North, Fudan University | Glioma | 12/23 | 12/23 | | |
NCT06358092: Two-dimensional Shear Wave Elastography for Assessment of Cirrhosis and Portal Hypertension |
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| Not yet recruiting | N/A | 112 | NA | Hepatic venous pressure gradient, Two-Dimensional Shear Wave Elastography | Third Affiliated Hospital, Sun Yat-Sen University | Cirrhosis, Liver, Portal Hypertension | 01/25 | 01/26 | | |
| ma, yingjie |
NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( ) |
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| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | IVA337, Lanifibranor, Placebo | Inventiva Pharma | NASH - Nonalcoholic Steatohepatitis | 09/25 | 09/26 | | |
NCT05395416: Antaitavir Hasophate Capsules Combined With Yiqibuvir Tablets in Treatment Adult Patients With Chronic Hepatitis C |
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| Recruiting | 2/3 | 520 | RoW | HEC74647PA+HEC110114, Antaitavir Hasophate+Yiqibuvir, Placebo | Sunshine Lake Pharma Co., Ltd. | Chronic HCV Infection | 04/23 | 04/23 | | |
NCT03977480: Phase II Study of Hemay007 in Patients With Active Ulcerative Colitis |
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| Terminated | 2 | 70 | RoW | Hemay007, Placebo | Tianjin Hemay Pharmaceutical Co., Ltd | Ulcerative Colitis | 08/22 | 08/22 | | |
| Zhang, Shuling |
| Completed | 3 | 1412 | RoW | Injection of recombinant human tissue plasminogen kinase derivatives, Reteplase, brand name: Ruitongli, r-PA, Recombinant human tissue plasminogen activator, Alteplase, brand name: Actilyse, rt-PA | Angde Biotech Pharmaceutical Co., Ltd., Beijing Tiantan Hospital | Acute Ischemic Stroke | 06/23 | 06/23 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
| Xu, Xing-xiang |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
| Xing, Li |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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NCT04901130: Impact of Real-time Automatic Quality Control System on Colorectal Adenoma Detection |
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| Not yet recruiting | N/A | 1254 | RoW | Computer-aided Real-time Automatic Quality Control System (AQCS) | Shandong University, Binzhou Medical University, Central Hospital of Shengli Oilfield, Linyi People's Hospital, Zibo municipal hospital, The People's Hospital of Zhaoyuan City | Colonoscopy | 01/22 | 01/22 | | |
| Yuan, Xueqian |
| Recruiting | 3 | 2100 | Europe, Canada, Japan, US, RoW | Rimegepant/BHV3000, Matching placebo | Pfizer | Pediatric Migraine | 01/29 | 01/29 | | |
| Guo, Shuxia |
NCT06142552: Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein |
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| Recruiting | 3 | 120 | RoW | FRSW117, Recombinant human coagulation factor Ⅷ-Fc fusion protein for injection | Jiangsu Gensciences lnc. | Severe Hemophilia A | 01/26 | 09/26 | | |
NCT05265286: A Study of Repeat Dosing of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection |
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| Completed | 2 | 15 | RoW | FRSW117, PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection | Jiangsu Gensciences lnc. | Severe Hemophilia A | 08/22 | 08/22 | | |
| Zhang, Xiao-ju |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
| Jia, Jin-guang |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
| Niu, Bing |
NCT06685978: Efficacy and Safety of Xiangjurupining Capsule for Hyperplasia of Mammary Glands |
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| Recruiting | 3 | 430 | RoW | Xiang Ju Ru Pi Ning capsule Placebo, Placebo group, Xiang Ju Ru Pi Ning capsule, Experimental group | Tasly Pharmaceutical Group Co., Ltd | Hyperplasia of Mammary Glands | 04/26 | 07/26 | | |
