Texas Cardiac Arrhythmia Institute Trials

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41 Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Natale, Andrea

CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation

Completed

339

Dronedarone, Multaq

American Heart Association, Duke Clinical Research Institute, Sanofi

Atrial Fibrillation

01/24

06/24

RAAFT-3, NCT04037397: First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment

Completed

Anti Arrhythmics, Pulmonary Vein Isolation performed by Radio Frequency Catheter Ablation

University of Pennsylvania, Biosense Webster, Inc., Texas Cardiac Arrhythmia Research Foundation

Atrial Fibrillation

10/24

PLEA, NCT04216667: Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation

Terminated

N/A

124

Europe, US, RoW

Catheter ablation

Montefiore Medical Center, Biosense Webster, Inc.

Atrial Fibrillation

06/23

AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting

N/A

484

Europe, Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/26

02/28

FULCRUM-VT, NCT05675865: Cryoablation for Monomorphic Ventricular Tachycardia

Recruiting

N/A

206

Canada, US

cryoablation procedure

Adagio Medical

Sustained VT

12/25

03/26

NCT06223789: VOLT-AF IDE Clinical Study

Active, not recruiting

N/A

435

Europe, Canada, US, RoW

Pulsed Field Ablation

Abbott Medical Devices

Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation

01/26

DISRUPT-AF, NCT06335082: A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

Enrolling by invitation

N/A

10000

Pulsed Field Ablation

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

Atrial Fibrillation

11/26

01/27

NCT05809596: HEAL-LAA Clinical Trial

Completed

N/A

949

WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure

Boston Scientific Corporation

Atrial Fibrillation, Bleeding, Stroke

07/24

09/25

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

ADVENT LTO, NCT06526546: ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study

Enrolling by invitation

N/A

583

Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

09/25

10/25

EFACT, NCT06699056: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Recruiting

N/A

1500

15-minutes of sitting during COR ECG Acquistion

Peerbridge Health, Inc

Ventricular Ejection Fraction, LVF, LV Dysfunction, Atrial Enlargement, Conduction Defect, Heart Failure, Valvular Heart Disease, Ischemic Heart Disease, Cardiotoxicity, Myocardial Infarction, Dilated Cardiomyopathy, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncope, Remodeling, Cardiac

09/25

NCT06676072: A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

Recruiting

N/A

188

Europe, US

PFA Ablation catheter

Abbott Medical Devices

Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation

04/26

ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation

Completed

N/A

669

Europe, Canada, US

Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/25

NCT07041125: Concomitant LAAC/AF Ablation (Watchman FLX Pro)

Recruiting

N/A

120

Watchman FLX™ Pro device.

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

PFA Ablation and LAAC Procedures

09/26

10/26

COHERENT-AF, NCT06784466: Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Recruiting

N/A

360

Europe, US, RoW

Argá Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System

Arga Medtech SA

Atrial Fibrillation (AF), Persistant Atrial Fibrillation, Paroxysmal AF

06/27

08/27

NCT05280093: HEAL-IST IDE Trial

Recruiting

N/A

142

Europe, US

AtriCure ISOLATOR Synergy Surgical Ablation System

AtriCure, Inc.

Inappropriate Sinus Tachycardia

06/26

06/27

NCT05107635: Inappropriate Sinus Tachycardia Registry

Recruiting

N/A

500

Europe, US

AtriCure Commercially Available Devices

AtriCure, Inc.

Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome

01/27

LAAOS-4, NCT05963698: The Fourth Left Atrial Appendage Occlusion Study

Recruiting

N/A

4000

Europe, Canada, US

WATCHMAN device

Hamilton Health Sciences Corporation, McMaster University, Population Health Research Institute, Boston Scientific Corporation

Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism

09/29

12/29

Tondo, Claudio

ARMYDA-AMULET, NCT05554822: Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study

Recruiting

574

Europe

Aspirin 100mg, Aspirin 100 mg OD plus clopidogrel 75 mg OD

Azienda Ospedaliero Universitaria Maggiore della Carita, Abbott Medical Devices

Left Atrial Appendage Occlusion, Antiplatelet Therapy

12/23

RIDGE, NCT06311708: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Recruiting

N/A

200

Europe, US

Tenaya Therapeutics, University of California, San Francisco, Brigham and Women's Hospital, New York University, University of Colorado, Denver, Johns Hopkins University, The Cleveland Clinic, Mayo Clinic, Medical University of South Carolina, Hopital Louis Pradel, Istituti Clinici Scientifici Maugeri SpA, The Queen Elizabeth Hospital, St George's University Hospitals NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Barts & The London NHS Trust, Skane University Hospital, Centro Cardiologico Monzino, Hôpital Haut-Lévêque, Nantes University Hospital, Pitié-Salpêtrière Hospital, Wuerzburg University Hospital, University Hospital Muenster

Arrhythmogenic Right Ventricular Cardiomyopathy

03/30

07/30

PSOT, NCT03481413: Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study

Terminated

N/A

566

Europe, US, RoW

Ablation

EPD Solutions, A Philips Company

Arrythmia

03/23

LESS-VT, NCT03490201: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

Completed

N/A

592

Europe, US, RoW

Market Approved RF Ablation System, FlexAbility SE Ablation Catheter

Abbott Medical Devices

Ventricular Tachycardia

04/24

AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting

N/A

484

Europe, Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/26

02/28

ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation

Completed

N/A

669

Europe, Canada, US

Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/25

NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry

Active, not recruiting

N/A

1000

Europe, Canada, US, RoW

Defibrillation using EV-ICD

Medtronic

Ventricular Arrhythmia, Tachycardia

05/30

10/37

Biase, Luigi Di

PLEA, NCT04216667: Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation

Terminated

N/A

124

Europe, US, RoW

Catheter ablation

Montefiore Medical Center, Biosense Webster, Inc.

Atrial Fibrillation

06/23

NCT05809596: HEAL-LAA Clinical Trial

Completed

N/A

949

WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure

Boston Scientific Corporation

Atrial Fibrillation, Bleeding, Stroke

07/24

09/25

ADVENT PAS, NCT06431815: ADVENT Post Approval Study

Active, not recruiting

N/A

228

Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation System, FARAWAVE™ Pulsed Field Ablation Catheter

Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

10/28

10/29

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

Cardinal, Deb

NCT05327101: Patient Preferences for Leadless Pacemakers

Completed

N/A

117

Patient Preference Survey

Abbott Medical Devices

Cardiac Rhythm Disorder, Bradycardia, Cardiac Pacemaker Artificial

06/23

DISRUPT-AF, NCT06335082: A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

Enrolling by invitation

N/A

10000

Pulsed Field Ablation

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

Atrial Fibrillation

11/26

01/27

INTEGRA-D, NCT05855135: Assessment of Combined CCM and ICD Device in HFrEF

Active, not recruiting

N/A

300

OPTIMIZER® Integra CCM-D System (Treatment Arm)

Impulse Dynamics

Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation

01/26

07/27

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

ABT-CIP-10523, NCT06707688: Abbott Medical - VERITAS Study

Active, not recruiting

N/A

458

Europe, Canada, US

Amulet™ 2 Left Atrial Appendage (LAA) Occluder

Abbott Medical Devices

Atrial Fibrillation (AF), Stoke

10/25

09/27

EFACT, NCT06699056: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Recruiting

N/A

1500

15-minutes of sitting during COR ECG Acquistion

Peerbridge Health, Inc

09/25

CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC

Recruiting

N/A

2650

Europe, Canada, Japan, US, RoW

Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC

Abbott Medical Devices

Atrial Fibrillation, Stroke, Bleeding

08/27

08/30

AIM HIGHer, NCT05064709: Assessment of CCM in HF With Higher Ejection Fraction

Recruiting

N/A

1500

Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF)

Impulse Dynamics

Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction, Diastolic Heart Failure

02/29

NCT07041125: Concomitant LAAC/AF Ablation (Watchman FLX Pro)

Recruiting

N/A

120

Watchman FLX™ Pro device.

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

PFA Ablation and LAAC Procedures

09/26

10/26

COHERENT-AF, NCT06784466: Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Recruiting

N/A

360

Europe, US, RoW

Argá Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System

Arga Medtech SA

Atrial Fibrillation (AF), Persistant Atrial Fibrillation, Paroxysmal AF

06/27

08/27

NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

Recruiting

N/A

620

OPTIMIZER Smart System

Impulse Dynamics

Heart Failure

03/26

NCT05280093: HEAL-IST IDE Trial

Recruiting

N/A

142

Europe, US

AtriCure ISOLATOR Synergy Surgical Ablation System

AtriCure, Inc.

Inappropriate Sinus Tachycardia

06/26

06/27

Ahmad, Amin

No trials found

Mohanty, Sanghamitra

No trials found

Rocca, Domenico G Della

No trials found

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Natale, Andrea

CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation

Completed

339

Dronedarone, Multaq

American Heart Association, Duke Clinical Research Institute, Sanofi

Atrial Fibrillation

01/24

06/24

RAAFT-3, NCT04037397: First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment

Completed

Anti Arrhythmics, Pulmonary Vein Isolation performed by Radio Frequency Catheter Ablation

University of Pennsylvania, Biosense Webster, Inc., Texas Cardiac Arrhythmia Research Foundation

Atrial Fibrillation

10/24

PLEA, NCT04216667: Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation

Terminated

N/A

124

Europe, US, RoW

Catheter ablation

Montefiore Medical Center, Biosense Webster, Inc.

Atrial Fibrillation

06/23

AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting

N/A

484

Europe, Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/26

02/28

FULCRUM-VT, NCT05675865: Cryoablation for Monomorphic Ventricular Tachycardia

Recruiting

N/A

206

Canada, US

cryoablation procedure

Adagio Medical

Sustained VT

12/25

03/26

NCT06223789: VOLT-AF IDE Clinical Study

Active, not recruiting

N/A

435

Europe, Canada, US, RoW

Pulsed Field Ablation

Abbott Medical Devices

Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation

01/26

DISRUPT-AF, NCT06335082: A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

Enrolling by invitation

N/A

10000

Pulsed Field Ablation

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

Atrial Fibrillation

11/26

01/27

NCT05809596: HEAL-LAA Clinical Trial

Completed

N/A

949

WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure

Boston Scientific Corporation

Atrial Fibrillation, Bleeding, Stroke

07/24

09/25

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

ADVENT LTO, NCT06526546: ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study

Enrolling by invitation

N/A

583

Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

09/25

10/25

EFACT, NCT06699056: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Recruiting

N/A

1500

15-minutes of sitting during COR ECG Acquistion

Peerbridge Health, Inc

09/25

NCT06676072: A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

Recruiting

N/A

188

Europe, US

PFA Ablation catheter

Abbott Medical Devices

Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation

04/26

ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation

Completed

N/A

669

Europe, Canada, US

Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/25

NCT07041125: Concomitant LAAC/AF Ablation (Watchman FLX Pro)

Recruiting

N/A

120

Watchman FLX™ Pro device.

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

PFA Ablation and LAAC Procedures

09/26

10/26

COHERENT-AF, NCT06784466: Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Recruiting

N/A

360

Europe, US, RoW

Argá Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System

Arga Medtech SA

Atrial Fibrillation (AF), Persistant Atrial Fibrillation, Paroxysmal AF

06/27

08/27

NCT05280093: HEAL-IST IDE Trial

Recruiting

N/A

142

Europe, US

AtriCure ISOLATOR Synergy Surgical Ablation System

AtriCure, Inc.

Inappropriate Sinus Tachycardia

06/26

06/27

NCT05107635: Inappropriate Sinus Tachycardia Registry

Recruiting

N/A

500

Europe, US

AtriCure Commercially Available Devices

AtriCure, Inc.

Inappropriate Sinus Tachycardia, Postural Tachycardia Syndrome

01/27

LAAOS-4, NCT05963698: The Fourth Left Atrial Appendage Occlusion Study

Recruiting

N/A

4000

Europe, Canada, US

WATCHMAN device

Hamilton Health Sciences Corporation, McMaster University, Population Health Research Institute, Boston Scientific Corporation

Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism

09/29

12/29

Tondo, Claudio

ARMYDA-AMULET, NCT05554822: Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study

Recruiting

574

Europe

Aspirin 100mg, Aspirin 100 mg OD plus clopidogrel 75 mg OD

Azienda Ospedaliero Universitaria Maggiore della Carita, Abbott Medical Devices

Left Atrial Appendage Occlusion, Antiplatelet Therapy

12/23

Recruiting

N/A

200

Europe, US

Arrhythmogenic Right Ventricular Cardiomyopathy

03/30

07/30

PSOT, NCT03481413: Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study

Terminated

N/A

566

Europe, US, RoW

Ablation

EPD Solutions, A Philips Company

Arrythmia

03/23

LESS-VT, NCT03490201: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

Completed

N/A

592

Europe, US, RoW

Market Approved RF Ablation System, FlexAbility SE Ablation Catheter

Abbott Medical Devices

Ventricular Tachycardia

04/24

AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Active, not recruiting

N/A

484

Europe, Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/26

02/28

ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation

Completed

N/A

669

Europe, Canada, US

Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System

Boston Scientific Corporation

Persistent Atrial Fibrillation

02/25

NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry

Active, not recruiting

N/A

1000

Europe, Canada, US, RoW

Defibrillation using EV-ICD

Medtronic

Ventricular Arrhythmia, Tachycardia

05/30

10/37

Biase, Luigi Di

PLEA, NCT04216667: Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation

Terminated

N/A

124

Europe, US, RoW

Catheter ablation

Montefiore Medical Center, Biosense Webster, Inc.

Atrial Fibrillation

06/23

NCT05809596: HEAL-LAA Clinical Trial

Completed

N/A

949

WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure

Boston Scientific Corporation

Atrial Fibrillation, Bleeding, Stroke

07/24

09/25

ADVENT PAS, NCT06431815: ADVENT Post Approval Study

Active, not recruiting

N/A

228

Canada, US, RoW

FARAPULSE™ Pulsed Field Ablation System, FARAWAVE™ Pulsed Field Ablation Catheter

Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

10/28

10/29

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

Cardinal, Deb

NCT05327101: Patient Preferences for Leadless Pacemakers

Completed

N/A

117

Patient Preference Survey

Abbott Medical Devices

Cardiac Rhythm Disorder, Bradycardia, Cardiac Pacemaker Artificial

06/23

DISRUPT-AF, NCT06335082: A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

Enrolling by invitation

N/A

10000

Pulsed Field Ablation

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

Atrial Fibrillation

11/26

01/27

INTEGRA-D, NCT05855135: Assessment of Combined CCM and ICD Device in HFrEF

Active, not recruiting

N/A

300

OPTIMIZER® Integra CCM-D System (Treatment Arm)

Impulse Dynamics

01/26

07/27

SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting

N/A

1857

WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device

Boston Scientific Corporation

Atrial Fibrillation, Stroke, Bleeding

07/26

01/27

ABT-CIP-10523, NCT06707688: Abbott Medical - VERITAS Study

Active, not recruiting

N/A

458

Europe, Canada, US

Amulet™ 2 Left Atrial Appendage (LAA) Occluder

Abbott Medical Devices

Atrial Fibrillation (AF), Stoke

10/25

09/27

EFACT, NCT06699056: AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Recruiting

N/A

1500

15-minutes of sitting during COR ECG Acquistion

Peerbridge Health, Inc

09/25

CATALYST, NCT04226547: Amplatzer Amulet LAAO Vs. NOAC

Recruiting

N/A

2650

Europe, Canada, Japan, US, RoW

Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC

Abbott Medical Devices

Atrial Fibrillation, Stroke, Bleeding

08/27

08/30

AIM HIGHer, NCT05064709: Assessment of CCM in HF With Higher Ejection Fraction

Recruiting

N/A

1500

Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF)

Impulse Dynamics

Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction, Diastolic Heart Failure

02/29

NCT07041125: Concomitant LAAC/AF Ablation (Watchman FLX Pro)

Recruiting

N/A

120

Watchman FLX™ Pro device.

Heart Rhythm Clinical and Research Solutions, LLC, Boston Scientific Corporation

PFA Ablation and LAAC Procedures

09/26

10/26

COHERENT-AF, NCT06784466: Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Recruiting

N/A

360

Europe, US, RoW

Argá Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System

Arga Medtech SA

Atrial Fibrillation (AF), Persistant Atrial Fibrillation, Paroxysmal AF

06/27

08/27

NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

Recruiting

N/A

620

OPTIMIZER Smart System

Impulse Dynamics

Heart Failure

03/26

NCT05280093: HEAL-IST IDE Trial

Recruiting

N/A

142

Europe, US

AtriCure ISOLATOR Synergy Surgical Ablation System

AtriCure, Inc.

Inappropriate Sinus Tachycardia

06/26

06/27

Ahmad, Amin

No trials found

Mohanty, Sanghamitra

No trials found

Rocca, Domenico G Della

No trials found

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