| Stone, Gregg W |
| Terminated | 3 | 248 | US, RoW | Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device | Coherex Medical, Biosense Webster, Inc. | Stroke | 12/23 | 12/23 | | |
RECHARGE:W, NCT06399692: REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women |
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| Recruiting | 3 | 600 | US | Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI) | Weill Medical College of Cornell University, Patient-Centered Outcomes Research Institute, Icahn School of Medicine at Mount Sinai | Coronary Artery Disease | 03/33 | 01/39 | | |
RECHARGE:M, NCT06399705: REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities |
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| Recruiting | 3 | 600 | US | Coronary artery bypass grafting, CABG, Percutaneous coronary intervention, PCI | Weill Medical College of Cornell University, Patient-Centered Outcomes Research Institute, Icahn School of Medicine at Mount Sinai | Coronary Artery Disease | 03/33 | 01/39 | | |
COAPT, NCT01626079: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The Trial) and CAS |
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| Active, not recruiting | N/A | 776 | Canada, US | MitraClip System, MitraClip device, MitraClip | Abbott Medical Devices | Mitral Regurgitation, Mitral Valve Regurgitation, Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects, Heart Failure | 03/19 | 07/24 | | |
NCT03507777: ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI) |
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| Completed | N/A | 2487 | Europe, Canada, Japan, US, RoW | Coronary PCI guided by OCT, Optical Coherence Tomography, Coronary PCI guided by Angiography | Abbott Medical Devices, Abbott | Coronary Artery Disease, Coronary Stenosis, Atherosclerosis, STEMI, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI) | 02/23 | 02/23 | | |
| Available | N/A | | US | Revivent TC System | BioVentrix | Heart Failure, Left Ventricle Remodeling | | | | |
| Active, not recruiting | N/A | 605 | Europe, Canada, US, RoW | V-Wave Interatrial Shunt, Control | V-Wave Ltd | Heart Failure | 10/23 | 10/27 | | |
| Active, not recruiting | N/A | 126 | Europe, US, RoW | Revivent TC | BioVentrix | Ventricular Dysfunction, Left | 12/23 | 06/27 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
| Active, not recruiting | N/A | 300 | Europe, US | MobiusHD, Sham Implantation | Vascular Dynamics, Inc. | Hypertension, Resistant Hypertension | 05/25 | 05/25 | | |
| Withdrawn | N/A | 300 | NA | PiCSO Impulse System | Miracor Medical SA | STEMI - ST Elevation Myocardial Infarction, Anterior Wall Myocardial Infarction | 07/25 | 06/28 | | |
AMIHOT III, NCT04743245: Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard. |
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| Recruiting | N/A | 434 | US | TherOx DownStream System, PCI | TherOx | Acute Myocardial Infarction, STEMI | 10/25 | 04/26 | | |
| Active, not recruiting | N/A | 4 | Europe, US | Impella CP®, Standard of Care | Abiomed Inc. | ST-segment Elevation Myocardial Infarction (STEMI), Cardiogenic Shock | 05/24 | 04/25 | | |
DEFINE GPS, NCT04451044: Distal Evaluation of Functional Performance With Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting |
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| Enrolling by invitation | N/A | 3212 | Europe, Canada, US, RoW | Philips SyncVision system with Philips pressure wires, standard of care angiographically-guided PCI | Philips Clinical & Medical Affairs Global | Coronary Artery Disease, Ischemic Heart Disease | 06/26 | 06/28 | | |
| Mehran, Roxana |
NCT01456013: Evaluation of RenalGuard® System to Reduce the Incidence of Contrast Induced Nephropathy in At-Risk Patients |
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| Active, not recruiting | 3 | 326 | US | RenalGuard Therapy, Standard Therapy | CardioRenal Systems, Inc. | Contrast Induced Nephropathy | 03/18 | 12/24 | | |
| Completed | N/A | 19000 | US | Percutaneous coronary intervention | Abbott Medical Devices, Icahn School of Medicine at Mount Sinai | Coronary Artery Disease, Percutaneous Coronary Intervention | 02/21 | 10/23 | | |
ABILITY, NCT04236609: Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents Versus Everolimus-Eluting Stents in Coronary Artery Disease Patients With Diabetes Mellitus Global |
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| Active, not recruiting | N/A | 3050 | Europe, RoW | Abluminus DES+ Sirolimus Eluting Stent System (SES), XIENCE Everolimus Eluting Coronary Stent System (XIENCE family) | Concept Medical Inc. | Diabetes, Coronary Artery Disease, Acute Coronary Syndrome | 10/23 | 09/24 | | |
| Active, not recruiting | N/A | 418 | Europe, Canada, US, RoW | SELUTION SLR™ DEB, Control | M.A. Med Alliance S.A., Iqvia Pty Ltd, Cordis Corporation | Coronary Restenosis | 07/25 | 08/29 | | |
| Active, not recruiting | N/A | 716 | Europe, Canada, US, RoW | Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems, Edwards SAPIEN 3 or SAPIEN 3 Ultra THV Systems | Medtronic Cardiovascular | Symptomatic Aortic Stenosis, Aortic Valve Stenosis, Aortic Valve Replacement | 11/23 | 12/27 | | |
| Completed | N/A | 322 | US | Jewel Patch Wearable Cardioverter Defibrillator (P-WCD) | Element Science, Inc. | Sudden Cardiac Arrest | 11/23 | 11/23 | | |
| Recruiting | N/A | 500 | NA | ProtEmbo - Cerebral Embolic Protection, Sentinel - Cerebral Embolic Protection | Protembis GmbH | Severe Aortic Valve Stenosis | 06/25 | 07/25 | | |
