| Nseir, Saad |
| Recruiting | 4 | 154 | Europe | ceftriaxone, ciprofloxacin, imipenem, linezolid, placebo | University Hospital, Lille, Ministry of Health, France | Mechanical Ventilation Complication, Critical Illness | 09/23 | 09/23 | | |
Corticop, NCT04163536: Comparison of Corticosteroids vs Placebo on Duration of Ventilatory Support During Severe Acute Exacerbations of COPD Patients in the ICU |
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| Recruiting | 3 | 440 | Europe | Methylprednisolone, Placebos | Versailles Hospital | Chronic Obstructive Pulmonary Disease | 10/25 | 03/26 | | |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
| Recruiting | N/A | 1136 | Europe | | University Hospital, Lille | Severe COVID-19 | 12/22 | 12/22 | | |
| Recruiting | N/A | 194 | Europe | Biomarker strategy, Routine strategy | University Hospital, Lille | Invasive Candidiasis | 06/24 | 06/25 | | |
| Recruiting | N/A | 296 | Europe | | University Hospital, Lille | Invasive Fungal Disease, Critical Illness | 09/23 | 09/23 | | |
ATOMIC, NCT04530760: Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation |
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| Recruiting | N/A | 226 | Europe | | University Hospital, Lille | Critical Illness, Cirrhosis, Liver | 10/23 | 10/23 | | |
HyperBetashock, NCT04748796: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility |
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| Recruiting | N/A | 360 | Europe | echocardiography, Landiolol | Centre Hospitalier Universitaire, Amiens, CH Dieppe, CH Elbeuf, CH Le Havre, Centre Hospitalier de Beauvais, CH Compiègne, CH Laon, University Hospital, Caen, CH Cherbourg, University Hospital, Lille, CH Douai, CH Montreuil, Centre Hospitalier de Roubaix, Centre Hospitalier de Bethune, CH Lomme, Centre Hospitalier de Lens, Tourcoing Hospital, Centre Hospitalier VALENCIENNES, Centre Hospitalier Arras, Hospital Ambroise Paré Paris, University Hospital, Brest, Henri Mondor University Hospital, Hospital Avicenne, University Hospital, Montpellier, CH Calais, Hôpital Edouard Herriot, Centre Hospitalier Universitaire de Nīmes, Groupe Hospitalier Pitié-Salpêtrière | Septic Shock, Tachycardia, Mortality During Septic Shock, Beta-blocker | 02/24 | 03/24 | | |
VAPERO, NCT03711331: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia |
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| Recruiting | N/A | 160 | Europe | FilmArray® Pneumonia panel plus, Standard care | University Hospital, Lille, Curetis GmbH | Pneumonia, Ventilator-Associated, Pneumonia, Bacterial | 06/24 | 06/24 | | |
| Recruiting | N/A | 740 | Europe, Canada, US, RoW | Respiratory Mechanics, Standard Ventilation Strategy | Unity Health Toronto, Canadian Institutes of Health Research (CIHR), University of Toronto, Applied Health Research Centre | ARDS | 11/25 | 03/26 | | |
APAPI, NCT03763799: Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation |
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| Recruiting | N/A | 266 | Europe | PCR-based microbiological diagnosis strategy, Standard microbiological diagnosis strategy | University Hospital, Lille | Aspiration Pneumonia | 12/24 | 03/25 | | |
| Recruiting | N/A | 20000 | Europe, RoW | VAP | European Clinical Research Alliance for Infectious Diseases (ECRAID), Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL), Université de Genève (UNIGE), University Medical Center Utrecht (UMCU) | Ventilator Associated Pneumonia | 12/25 | 03/26 | | |
ASPIC, NCT05671328: Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia |
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| Not yet recruiting | N/A | 261 | NA | Biological examinations performed on blood and BAL | University Hospital, Lille, Pfizer | Ventilator Associated Pneumonia, Pulmonary Aspergillosis Invasive | 03/25 | 03/25 | | |
| TAVERNIER, Benoit |
| Completed | 4 | 18 | Europe | Prothrombin Complex Concentrate, Fresh Frozen Plasma | Fondation Ophtalmologique Adolphe de Rothschild | Intracranial Hemorrhages | 03/19 | 03/19 | | |
DETERMINE, NCT04352296: Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke |
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| Recruiting | N/A | 432 | Europe | Individualized blood pressure, Standard blood pressure | Fondation Ophtalmologique Adolphe de Rothschild, Ministry of Health, France | Acute Cerebrovascular Accident | 09/23 | 11/24 | | |
| Simonin, Clémence |
| Recruiting | N/A | 100 | Europe | | University Hospital, Lille | Huntington Disease | 10/23 | 10/23 | | |
| Recruiting | N/A | 90 | Europe | | University Hospital, Lille | Huntington Disease | 02/25 | 02/25 | | |
| GARRIGUE, Delphine |
| Recruiting | N/A | 1000 | Europe | | University Hospital, Lille | Infection Viral, Coronavirus, COVID-19 | 04/21 | 04/21 | | |
| Recruiting | N/A | 984 | Europe, RoW | Transcranial Doppler (TCD) | University Hospital, Grenoble | Mild Traumatic Brain Injury | 05/25 | 07/26 | | |
NCT05376462: Quantra® System With the QStat® Cartridge in Trauma |
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| Completed | N/A | 36 | Europe | Quantra System with the QStat Cartridge, Standard Laboratory Tests | HemoSonics LLC, University Hospital, Lille | Trauma, Coagulation Defect; Bleeding | 01/24 | 01/24 | | |
| NSEIR, Saadalla |
NESOI-2, NCT05867875: Non-invasive Early Oxygen- Reserve-index (ORI) Determination to Prevent Hypoxaemia During Endotracheal Intubation |
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| Recruiting | N/A | 950 | Europe | Unblinded ORI values, Blinded ORI values | Nantes University Hospital | Intensive Care Unit | 02/25 | 03/25 | | |
| Not yet recruiting | N/A | 754 | Europe | Strategy for continuing oral intake, Fasting strategy | University Hospital, Tours | Patient in Acute Respiratory Failure, Continuation of Oral Intake | 09/27 | 10/27 | | |
APAPI, NCT03763799: Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation |
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| Recruiting | N/A | 266 | Europe | PCR-based microbiological diagnosis strategy, Standard microbiological diagnosis strategy | University Hospital, Lille | Aspiration Pneumonia | 12/24 | 03/25 | | |
| ANTOINE, Pascal |
| Recruiting | N/A | 90 | Europe | | University Hospital, Lille | Huntington Disease | 02/25 | 02/25 | | |
| Davion, Jean-Baptiste |
ULYSSES, NCT05933057: Efficacy, Safety and Tolerability of Givinostat in Non-ambulant Patients With Duchenne Muscular Dystrophy |
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| Recruiting | 3 | 138 | Europe, Canada | Givinostat, ITF2357, Placebo | Italfarmaco, Fortrea | Duchenne Muscular Dystrophy | 02/28 | 02/28 | | |
NatHis-CNM, NCT03351270: Prospective Natural History Study of Patients With Myotubular Myopathy and Other CentroNuclear Myopathies |
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| Completed | N/A | 60 | Europe | Standardized strength, respiratory and motor function assessments | Institut de Myologie, France, Dynacure | Centronuclear Myopathy | 09/21 | 09/21 | | |
| Not yet recruiting | N/A | 60 | Europe | Strength force measurment, MyoGrip/Pinch, Time tests, 10mWT, 30STS, 6MWT, 9HPT, Motor scales, Questionnaires, Accelerometry, MNR, Bio-impedance analysis | Institut de Myologie, France, Roche Pharma AG | Muscular Atrophy, Spinal, Type II, Muscular Atrophy, Spinal, Type III | 01/24 | 01/24 | | |
PHENO SMART, NCT06321965: Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy |
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| Recruiting | N/A | 60 | Europe | evaluation of muscle function, First-line cognitive assessment, second-line cognitive assessment, Cardiac evaluation, MRI, Assessment of activity and muscle fatigue, Assessment of bulbar function, Evaluation of body composition and metabolism, Questionnaires, Biocollection, Skinfold measurement | Hospices Civils de Lyon | Spinal Muscular Atrophy | 01/28 | 01/28 | | |
SMAII, NCT04159987: Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA® |
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| Completed | N/A | 20 | Europe | Spinraza intrathecal injection | Centre Hospitalier Universitaire de Nice | Spinal Muscular Atrophy | 07/24 | 07/24 | | |
| Completed | N/A | 70 | Europe | Items completion with or without a MFM-Play | Hospices Civils de Lyon | Neuromuscular Diseases | 07/24 | 07/24 | | |
