| Childs, Richard W |
NCT03520647: Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis |
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| Recruiting | 2 | 56 | US | Cyclophosphamide, Peripheral Blood Stem Cells | National Heart, Lung, and Blood Institute (NHLBI) | Severe Aplastic Anemia (SAA), Hypo-Plastic Myelodysplastic Syndrome (MDS), Paroxysmal Nocturnal Hemoglobinuria (PNH) | 06/25 | 06/28 | | |
NCT01656603: Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation |
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| Recruiting | 2 | 9999 | US | unlicensed CBU | New York Blood Center | Infusion Reactions | 12/25 | 12/25 | | |
NCT01174108: Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells |
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| Recruiting | 2 | 120 | US | Miltenyi CD34 Reagent System, Donor derived G-CSF mobilized PBC | National Heart, Lung, and Blood Institute (NHLBI) | Severe Aplastic Anemia, MDS (Myelodysplastic Syndrome) | 12/25 | 06/28 | | |
NCT05502783: Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias |
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| Recruiting | 2 | 20 | US | fostamatinib | National Heart, Lung, and Blood Institute (NHLBI) | Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD | 04/26 | 04/26 | | |
NCT05509582: Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias |
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| Enrolling by invitation | 2 | 20 | US | fostamatinib | National Heart, Lung, and Blood Institute (NHLBI) | Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD | 12/28 | 12/28 | | |
NCT01861093: Safety Study of Cord Blood Units for Stem Cell Transplants |
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| Recruiting | 2 | 500 | US | Cord Blood Units | National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), National Cord Blood Program, New York Blood Center | Aplastic Anemia, Leukemia, Myelodysplastic Syndrome (MDS), Lymphoma | 11/37 | 11/37 | | |
NCT03173937: Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome |
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| Recruiting | 1/2 | 37 | US | Omidubicel (former CordIn), Miltenyi CliniMACS(R) CD34 Reagent System | National Heart, Lung, and Blood Institute (NHLBI) | Severe Aplastic Anemia, Hypo-Plastic MDS, Myelodysplastic Syndrome (MDS) | 04/25 | 03/28 | | |
NCT01553461: Transplants With Unlicensed Preserved Cord Blood |
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| Recruiting | 1/2 | 500 | US | Cord Blood Transplant | National Heart, Lung, and Blood Institute (NHLBI) | Myelodysplastic Syndrome (MDS), Hematologic Neoplasms, Hematologic Diseases, Severe Aplastic Anemia | 10/36 | 10/36 | | |
NCT03354390: HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma |
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| Active, not recruiting | 1 | 17 | US | cell infusion | National Heart, Lung, and Blood Institute (NHLBI), Loyola University Medical Center (LUMC) | Kidney Cancer | 10/23 | 03/26 | | |
NCT00106925: Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants |
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| Recruiting | N/A | 1000 | US | | National Heart, Lung, and Blood Institute (NHLBI) | Graft-versus-leukemia, Graft vs Host Disease, Graft Rejection | | | | |
NCT00071045: Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members |
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| Recruiting | N/A | 6000 | US | | National Heart, Lung, and Blood Institute (NHLBI) | Neoplasms, Hematologic Neoplasms, Healthy Volunteers | | | | |
NCT01351545: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) |
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| Recruiting | N/A | 99999 | US | A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) | Center for International Blood and Marrow Transplant Research, National Marrow Donor Program | Hematologic Malignancies, Inherited Disorders of Metabolism, Inherited Abnormalities of Platelets, Histiocytic Disorders, Acute Myelogenous Leukemia (AML or ANLL), Acute Lymphoblastic Leukemia (ALL), Other Acute Leukemia, Chronic Myelogenous Leukemia (CML), Myelodysplastic (MDS) / Myeloproliferative (MPN) Diseases, Other Leukemia, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Multiple Myeloma/ Plasma Cell Disorder (PCD), Inherited Abnormalities of Erythrocyte Differentiation or Function, Disorders of the Immune System, Autoimmune Diseases, Severe Aplastic Anemia | 10/41 | 10/41 | | |
