Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust
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 6 Trials 
10 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Menne, Tobias
ALLTogether1, NCT04307576 / 2018-001795-38: A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Recruiting
3
6430
Europe, RoW
Omitted Doxorubicin, Omitted Vincristine+Dexamethasone pulses, Inotuzumab Ozogamicin+Standard Maintenance Therapy, Besponsa+Maintenance Therapy, Imatinib, 6-tioguanine+Standard Maintenance Therapy, Blinatumomab, Blincyto
Mats Heyman, The Swedish Research Council, The Swedish Childhood Cancer Foundation, Pfizer, Servier, NordForsk, Aamu Pediatric Cancer Foundation, German Society for Pediatric Oncology and Hematology GPOH gGmbH, Clinical Trial Center North (CTC North GmbH & Co. KG), Belgium Health Care Knowledge Centre, Karolinska Institutet, Cancer Research UK, Fundação Rui Osório de Castro, Acreditar - Associação de Pais e Amigos das Crianças com Cancro, Grupo Português De Leucemias Pediátricas, Amgen, Nova Laboratories Limited, Danish Child Cancer Foundation, Danish Cancer Society, The Novo Nordic Foundation, Assistance Publique - Hôpitaux de Paris, Direction Générale de l'Offre de Soins
Leukemia, Acute Lymphoblastic
06/27
06/32
SeluDex, NCT03705507 / 2016-003904-29: International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Terminated
1/2
12
Europe
Selumetinib, AZD6244, Dexamethasone
University of Birmingham, Cancer Research UK, AstraZeneca
Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, Adult, Acute Lymphoblastic Leukemia, Pediatric, Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia Recurrent
05/23
05/23
NCT03590574 / 2017-001965-26: Phase I/II Study Evaluating AUTO4 in Patients with TRBC1 Positive T Cell Lymphoma

Active, not recruiting
1/2
200
Europe
AUTO4
Autolus Limited
T Cell Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Angioimmunoblastic T-cell Lymphoma, Anaplastic Large Cell Lymphoma
10/26
10/26
FELIX, NCT04404660: A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients with Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

Hourglass Jul 2024 - Dec 2024 : Submission in UK for adult r/r B-ALL
Active, not recruiting
1/2
153
NA
AUTO1, Obecabtagene autoleucel (obe-cel)
Autolus Limited
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
05/25
05/25
Osborne, Wendy
RADAR, NCT04685616: Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Recruiting
3
1042
Europe, Canada, US, RoW
Involved site radiotherapy, Doxorubicin, Bleomycin, Brentuximab vedotin, Vinblastine, Dacarbazine, Haematopoietic growth factor, Filgrastim, G-CSF, Pegfilgrastim
University College, London, Takeda, University of Miami, European Organisation for Research and Treatment of Cancer - EORTC, Australasian Leukaemia and Lymphoma Group, Seagen Inc., Canadian Cancer Trials Group
Hodgkin Lymphoma
09/30
09/32
Smith, Stuart
NCT05594823: Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study

Recruiting
4
30
Canada
Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide
Lawson Health Research Institute
Heart Failure, Heart Diseases
07/23
07/23
FUTURE-GB, NCT05399524: Functional and Ultrasound Guided Resection of Glioblastoma

Recruiting
3
357
Europe
Standard of Care, Additional pre- and intra-operative imaging, DTI, IUS
University of Oxford, Imperial College Healthcare NHS Trust, Efficacy and Mechanism Evaluation (EME) Programme
Glioma Glioblastoma Multiforme
10/25
11/25
NCT05772442: Cardiac Transplant Metabolomics With and Without Rejection

Not yet recruiting
N/A
100
NA
Extra blood samples (5-10 mL) drawn
Western University, Canada, Canadian Cardiovascular Society, Bayer, University of Alberta, Queen's University
Heart Transplant Rejection
10/25
04/26
NCT04274283: Tessa Jowell BRAIN MATRIX - Platform Study

Recruiting
N/A
1000
Europe
Matched Tumour and Blood Sample - Research Pathway, Matched Tumour and Blood Sample - NHS GMS pathway
University of Birmingham, The Brain Tumour Charity, University of Oxford, University of Edinburgh, Genomics England
Glioma
03/26
03/27
HF-FIM, NCT04590001: Effect of the MobiusHD® in Patients With Heart Failure

Recruiting
N/A
50
Europe, Canada, RoW
MobiusHD
Vascular Dynamics, Inc.
Heart Failure With Reduced Ejection Fraction
12/25
06/26
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Menne, Tobias
ALLTogether1, NCT04307576 / 2018-001795-38: A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Recruiting
3
6430
Europe, RoW
Omitted Doxorubicin, Omitted Vincristine+Dexamethasone pulses, Inotuzumab Ozogamicin+Standard Maintenance Therapy, Besponsa+Maintenance Therapy, Imatinib, 6-tioguanine+Standard Maintenance Therapy, Blinatumomab, Blincyto
Mats Heyman, The Swedish Research Council, The Swedish Childhood Cancer Foundation, Pfizer, Servier, NordForsk, Aamu Pediatric Cancer Foundation, German Society for Pediatric Oncology and Hematology GPOH gGmbH, Clinical Trial Center North (CTC North GmbH & Co. KG), Belgium Health Care Knowledge Centre, Karolinska Institutet, Cancer Research UK, Fundação Rui Osório de Castro, Acreditar - Associação de Pais e Amigos das Crianças com Cancro, Grupo Português De Leucemias Pediátricas, Amgen, Nova Laboratories Limited, Danish Child Cancer Foundation, Danish Cancer Society, The Novo Nordic Foundation, Assistance Publique - Hôpitaux de Paris, Direction Générale de l'Offre de Soins
Leukemia, Acute Lymphoblastic
06/27
06/32
SeluDex, NCT03705507 / 2016-003904-29: International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Terminated
1/2
12
Europe
Selumetinib, AZD6244, Dexamethasone
University of Birmingham, Cancer Research UK, AstraZeneca
Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, Adult, Acute Lymphoblastic Leukemia, Pediatric, Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia Recurrent
05/23
05/23
NCT03590574 / 2017-001965-26: Phase I/II Study Evaluating AUTO4 in Patients with TRBC1 Positive T Cell Lymphoma

Active, not recruiting
1/2
200
Europe
AUTO4
Autolus Limited
T Cell Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Angioimmunoblastic T-cell Lymphoma, Anaplastic Large Cell Lymphoma
10/26
10/26
FELIX, NCT04404660: A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients with Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

Hourglass Jul 2024 - Dec 2024 : Submission in UK for adult r/r B-ALL
Active, not recruiting
1/2
153
NA
AUTO1, Obecabtagene autoleucel (obe-cel)
Autolus Limited
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
05/25
05/25
Osborne, Wendy
RADAR, NCT04685616: Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Recruiting
3
1042
Europe, Canada, US, RoW
Involved site radiotherapy, Doxorubicin, Bleomycin, Brentuximab vedotin, Vinblastine, Dacarbazine, Haematopoietic growth factor, Filgrastim, G-CSF, Pegfilgrastim
University College, London, Takeda, University of Miami, European Organisation for Research and Treatment of Cancer - EORTC, Australasian Leukaemia and Lymphoma Group, Seagen Inc., Canadian Cancer Trials Group
Hodgkin Lymphoma
09/30
09/32
Smith, Stuart
NCT05594823: Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study

Recruiting
4
30
Canada
Ambulatory heart failure management with Flexible Diuretic Regimen with furosemide, Ambulatory heart failure management with fixed dose furosemide
Lawson Health Research Institute
Heart Failure, Heart Diseases
07/23
07/23
FUTURE-GB, NCT05399524: Functional and Ultrasound Guided Resection of Glioblastoma

Recruiting
3
357
Europe
Standard of Care, Additional pre- and intra-operative imaging, DTI, IUS
University of Oxford, Imperial College Healthcare NHS Trust, Efficacy and Mechanism Evaluation (EME) Programme
Glioma Glioblastoma Multiforme
10/25
11/25
NCT05772442: Cardiac Transplant Metabolomics With and Without Rejection

Not yet recruiting
N/A
100
NA
Extra blood samples (5-10 mL) drawn
Western University, Canada, Canadian Cardiovascular Society, Bayer, University of Alberta, Queen's University
Heart Transplant Rejection
10/25
04/26
NCT04274283: Tessa Jowell BRAIN MATRIX - Platform Study

Recruiting
N/A
1000
Europe
Matched Tumour and Blood Sample - Research Pathway, Matched Tumour and Blood Sample - NHS GMS pathway
University of Birmingham, The Brain Tumour Charity, University of Oxford, University of Edinburgh, Genomics England
Glioma
03/26
03/27
HF-FIM, NCT04590001: Effect of the MobiusHD® in Patients With Heart Failure

Recruiting
N/A
50
Europe, Canada, RoW
MobiusHD
Vascular Dynamics, Inc.
Heart Failure With Reduced Ejection Fraction
12/25
06/26

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