| Zhao, Wei |
PIP/TAZO, NCT05981079: Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis. |
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| Recruiting | 4 | 332 | RoW | Piperacillin/tazobactam | Shandong University, Shandong Provincial Hospital, Qianfoshan Hospital, Jinan Maternity and Child Care Hospital, Yantai Yuhuangding Hospital, Hebei Petro China Center Hospital, Shengli Oilfield Hospital, Liaocheng People's Hospital, Jining Medical University, W.F. Maternal and Child Health Hospital, Taian City Central Hospital | Late-Onset Neonatal Sepsis | 12/24 | 05/25 | | |
NCT06780410: A Clinical Study to Evaluate the Efficacy, Tolerability, and Safety of Bempedoic Acid |
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| Recruiting | 3 | 240 | RoW | Bempedoic Acid Tablet, Placebo | Gan & Lee Pharmaceuticals. | Primary Hyperlipidemia | 10/25 | 10/25 | | |
NCT04228393: The Individualized Treatment of 6-mercaptopurine in Children With Acute Lymphoblastic Leukemia in China |
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| Not yet recruiting | 2/3 | 82 | RoW | 6-mercaptopurine, 6-MP, Standard treatment, Individualized treatment | Wei Zhao, Institute of Hematology & Blood Diseases Hospital, Qianfoshan Hospital, Qilu Hospital of Shandong University, Children's Hospital of Hebei Province, The Affiliated Hospital of Qingdao University | Acute Lymphoblastic Leukemia, Pediatric | 12/22 | 12/22 | | |
NCT05429723: First-in-Human Study to Investigate the Safety and Tolerability and Pharmacokinetics of HS-10383 |
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| Recruiting | 1 | 32 | RoW | HS-10383, HS-10383 Placebo | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Cough | 06/22 | 06/22 | | |
NCT05339646: A Phase I Clinical Study of SSD8432 in Healthy Adult Subjects |
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| Recruiting | 1 | 108 | RoW | SSD8432 dose 1~7 and Ritonavir, SSD8432 dose 8~9, SSD8432 dose 10~12 and ritonavir, SSD8432 dose 13 and Ritonavir, SSD8432 dose 14 and Ritonavir | Jiangsu Simcere Pharmaceutical Co., Ltd. | Healthy Participants | 10/22 | 12/22 | | |
NCT05665647: Drug-Drug Interaction Study of Itraconazole, Rifampicin and Midazolam With SIM0417/Ritonavir in Healthy Participants |
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| Completed | 1 | 36 | RoW | Cohort 1: SIM0417/ritonavir and itraconazole, Interaction between SIM0417/ritonavir and itraconazole, Cohort 2: SIM0417/ritonavir and rifampicin, Interaction between SIM0417/ritonavir and rifampicin, Cohort 3: SIM0417/ritonavir and midazolam, Interaction between SIM0417/ritonavir and midazolam | Jiangsu Simcere Pharmaceutical Co., Ltd. | Healthy Volunteers | 01/23 | 02/23 | | |
NCT05947097: A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment |
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| Recruiting | 1 | 32 | RoW | HSK21542 Injection | Haisco Pharmaceutical Group Co., Ltd. | Renal Impairment | 07/23 | 12/23 | | |
NCT05826249: Safety and Pharmacokinetics of SIM0417 Combined With Ritonavir in Healthy Elderly Subjects |
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| Recruiting | 1 | 20 | RoW | SIM0417/Ritonavir, 750 mg SIM0417/100 mg ritonavir | Jiangsu Simcere Pharmaceutical Co., Ltd. | Elder | 09/23 | 11/23 | | |
NCT06747520: Phase 1 Renal Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride |
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| Completed | 1 | 24 | RoW | ET-26HCl | Ahon Pharmaceutical Co., Ltd. | Renal Insufficiency | 02/24 | 02/24 | | |
NCT05731804: Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir |
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| Not yet recruiting | 1 | 72 | RoW | SIM0417 600 mg; Ritonavir100 mg, SIM0417 375 mg; Ritonavir100 mg, SIM0417 750 mg; Ritonavir100 mg | Jiangsu Simcere Pharmaceutical Co., Ltd. | Renal Impairment, Hepatic Impairment | 12/23 | 12/23 | | |
NCT06214858: The Safety, Tolerability, Pharmacokinetics and Food Effects of SHEN211 Tablet in Healthy Subjects |
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| Recruiting | 1 | 76 | RoW | SHEN211 tablets, SHEN211 placebo tablets | JKT Biopharma Co., Ltd. | Phase 1 | 04/24 | 04/24 | | |
NCT06764147: Safety and Pharmacokinetics/ Pharmacodynamics of Methoxyethyl Etomidate Hydrochloride in Healthy Elderly Subjects |
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| Completed | 1 | 16 | RoW | ET-26HCl | Ahon Pharmaceutical Co., Ltd. | Healthy Elderly Subjects | 02/24 | 02/24 | | |
NCT06092983: A Multiple-Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of HS-10383 |
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| Recruiting | 1 | 48 | RoW | HS-10383, HS-10383 Tablets, HS-10383 Placebo, HS-10383 Placebo Tablets | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Cough | 12/23 | 12/23 | | |
NCT06220214: Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer |
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| Recruiting | 1 | 30 | US | CEDM, CEDBT, Omnipaque 350mgI/mL Solution for Injection | Alison Stopeck | Breast Cancer, Locally Advanced Breast Cancer, Neoadjuvant Chemotherapy, HER2-positive Breast Cancer, Triple Negative Breast Cancer, TNBC, Triple Negative Breast Cancer | 07/26 | 08/26 | | |
NCT06428903: Comparative Bioavailability Study of Tablet and Granule Formulations of ADC189 and the Study of Ultra-high Dose |
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| Recruiting | 1 | 40 | RoW | ADC189 tablet, ADC189 granules, ADC189 180mg | Jiaxing AnDiCon Biotech Co.,Ltd | Healthy Volunteer | 07/24 | 07/24 | | |
NCT06313697: A Study to Evaluate the Safety, Immunogenicity, and Pharmacokinetics of GR2102 in Healthy Adult |
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| Recruiting | 1 | 132 | RoW | GR2102 injection, placebo | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | Respiratory Syncytial Virus Infections | 01/25 | 12/25 | | |
NCT05777109: Comparing of the PK, PD, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults |
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| Recruiting | 1 | 180 | RoW | HS-20090, Recombinant human anti-RANKL monoclonal antibody injection, Xgeva®, Denosumab Injection | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Healthy | 04/24 | 04/24 | | |
NCT06536036: Evaluate the Effects of Food on the Pharmacokinetics of SIM0270 |
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| Completed | 1 | 16 | RoW | SIM0270 | Jiangsu Simcere Pharmaceutical Co., Ltd., Nanjing Zaiming Pharmaceutical Co., Ltd. | Healthy Participants | 10/24 | 10/24 | | |
| Completed | 1 | 6 | RoW | [14C] HRS-5965 | Chengdu Suncadia Medicine Co., Ltd. | Complement Mediated Primary or Secondary Glomerular Diseases | 10/24 | 10/24 | | |
HRS-9231-103, NCT06657560: Pharmacokinetics, Dialysability and Safety of HRS-9231 in Healthy Volunteers and in Patients With Impaired Renal Function |
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| Recruiting | 1 | 40 | RoW | HRS-9231 | Shanghai Shengdi Pharmaceutical Co., Ltd | Contrast-Enhanced Magnetic Resonance Imaging Detection | 04/25 | 04/25 | | |
NCT06598956: To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Renal Impairment Subjects |
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| Not yet recruiting | 1 | 32 | RoW | TQ05105 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Myelofibrosis | 07/25 | 08/25 | | |
| Active, not recruiting | 1 | 6 | RoW | [14C] SIM0270 Oral Preparation | Jiangsu Simcere Pharmaceutical Co., Ltd., Nanjing Zaiming Pharmaceutical Co., Ltd. | Healthy Participants | 03/25 | 03/25 | | |
NCT06672276: To Evaluate the Pharmacokinetics and Safety of TQD3606 for Injection in Subjects With Renal Insufficiency |
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| Not yet recruiting | 1 | 32 | RoW | TQD3606 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Resistant to Gram-positive, Gram-negative and Anaerobic Bacteria | 05/25 | 11/25 | | |
NCT06671873: Study on Mass Balance of [14C]HMPL-306（Isocitrate Dehydrogenase Inhibitor） in Healthy Chinese Adult Male Subjects |
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| Recruiting | 1 | 8 | RoW | 100 µCi [14C] HMPL-306, 100 µCi [14C] HMPL-306 suspension | Hutchmed | Mass Balance Study | 03/25 | 06/25 | | |
NCT06779253: A Study to Investigate the Effect of Pimicotinib on the Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin in Healthy Subjects |
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| Not yet recruiting | 1 | 38 | RoW | pimicotinib capsules | Abbisko Therapeutics Co, Ltd | Healthy Subjects | 05/25 | 06/25 | | |
NCT05930704: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-2017 Injection in Postmenopausal Women |
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| Recruiting | 1 | 45 | RoW | SHR-2017 injection, Placebo | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Osteoporosis | 04/25 | 04/25 | | |
NCT04799626: Population Pharmacokinetics and Dosage Individualization of Antibiotics in Elderly Patients |
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| Recruiting | N/A | 500 | RoW | biapenem,meropenem,piperacillin and tazobactam,tigecycline,levofloxacin.etc | Shandong University, The Second Hospital of Shandong University | Elderly Infection | 03/23 | 06/23 | | |
NCT06711575: Model-informed Individualized Treatment of Anti-Infective Drugs in Patients With Spinal Infections |
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| Recruiting | N/A | 300 | RoW | Anti-Infective Drugs | Shandong University, Shandong Public Health Clinical Center | Infectious Diseases of Spine | 10/26 | 10/26 | | |
NCT06711562: Model-informed Individualized Treatment of Anti-infective Drugs |
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| Recruiting | N/A | 300 | RoW | Anti-Infective Drugs | Shandong University | Osteoarticular Infections | 10/26 | 10/26 | | |
NCT03113344: Population Pharmacokinetics of Anti-infective Drugs in Children With Infectious Diseases |
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| Recruiting | N/A | 800 | RoW | cephalosporins,penicillins,macrolides,carbapenems and antiviral drugs, latamoxef, ceftriaxone, ceftazidime, ampicillin, penicillin, amoxicillin, erythromycin, azithromycin, meropenem, imipenem, ganciclovir, acyclovir | Beijing Children's Hospital, Shandong University, Hopital Universitaire Robert-Debre, Rennes University Hospital | Children; Infection | 10/25 | 12/25 | | |
NCT03933748: Therapeutic Drug Monitoring of Teicoplanin in Children |
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| Recruiting | N/A | 500 | RoW | Teicoplanin-PMMA | Shandong University, Qianfoshan Hospital, Shandong Provincial Hospital, Affiliated Hospital of Qinghai University, Jinan children's hospital, Yantai Yuhuangding Hospital, Jinan Central Hospital, Liaocheng People's Hospital, Shandong Tumor Hospital, Weifang People's Hospital, Linyi People's Hospital, Affiliated hospital of jining medical college, Weihai maternal and child health care hospital, The Second Hospital of Shandong University | Bacterial Infections | 11/25 | 12/25 | | |
NCT04771884: Population Pharmacokinetics of Commonly Used Antimicrobial Agents in Children of Bacterial Meningitis With Augmented Renal Clearance |
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| Recruiting | N/A | 300 | RoW | meropenem vancomycin ceftazidime ceftriaxone ceftizoxime linezolid | Shandong University, Children's Hospital of Chongqing Medical University | Bacterial Meningitis, Augmented Renal Clearance | 01/26 | 03/26 | | |
NCT06076200: Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations |
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| Recruiting | N/A | 50 | RoW | Piperacillin Sodium and Tazobactam Sodium for Injection | Shandong University, Shandong Provincial Hospital | Early-Onset Neonatal Sepsis | 07/26 | 12/26 | | |
NCT03625739: Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis |
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| Recruiting | N/A | 800 | RoW | anti-tuberculosis drug, Isoniazid, Rifampicin, Pyrazinamide, Ethambutol, Levofloxacin, Moxifloxacin, Gatifloxacin, Amikacin, Capreomycin, Kanamycin (Streptomycin), Ethionamide, Cycloserine, terizidone, Clofazimine, Bedaquiline, Delamanid, p-aminosalicylic acid, Imipenem-cilastatind, Amoxicillin-clavulanate, Thioacetazone | Beijing Children's Hospital, Shandong University, Hopital Universitaire Robert-Debre, Rennes University Hospital | Tuberculosis | 10/26 | 12/26 | | |
NCT04849195: Comparison of Different Feature Engineering Methods for Automated ICD Coding |
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| Active, not recruiting | N/A | 6947 | RoW | No intervention | China National Center for Cardiovascular Diseases | Cardiovascular Diseases | 04/21 | 04/21 | | |
NCT04817423: Automated ICD Coding of Primary Diagnosis Based on Machine Learning |
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| Active, not recruiting | N/A | 74880 | RoW | No intervention | China National Center for Cardiovascular Diseases | Cardiovascular Diseases | 04/21 | 04/21 | | |
NCT04970979: Exercise Adherence in Home-based Cardiac Rehabilitation |
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| Not yet recruiting | N/A | 300 | RoW | survey | Peking University Third Hospital | Coronary Artery Disease | 02/22 | 02/22 | | |
NCT05463614: Population Pharmacokinetics of Propafenone and Propranolol in Children Patients |
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| Recruiting | N/A | 500 | RoW | Propafenone and Propranolol | Shandong University | Arrhythmia | 08/22 | 12/25 | | |
NCT04397913: Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Children With PDA |
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| Recruiting | N/A | 500 | RoW | Paracetamol, Acetaminophen, Ibuprofen | Shandong University, West China Second University Hospital | Patent Ductus Arteriosus | 01/23 | 05/23 | | |
NCT04379180: Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN |
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| Not yet recruiting | N/A | 500 | RoW | Bosentan Tablets, Sildenafil Tablet, Tadalafil Tablets | Shandong University, West China Second University Hospital | Persistent Pulmonary Hypertension of the Newborn | 02/23 | 05/23 | | |
| Recruiting | N/A | 40000000 | RoW | Data analysis | Shandong University, National Health Medical Data (North Center) | Common Diseases, Rare Diseases | 07/23 | 07/24 | | |
| Recruiting | N/A | 300 | RoW | Tigecycline | Shandong University, Shandong Provincial Hospital | Infectious Disease | 07/25 | 12/25 | | |
| Recruiting | N/A | 500 | RoW | antiepileptic drugs | Wei Zhao, Shandong Provincial Qianfoshan Hospital, The Second Hospital of Shandong University, The Affiliated Hospital of Qingdao University | Seizure, Epileptic | 03/28 | 06/28 | | |
