Yeovil District Hospital
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 29 Trials 
42 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Brown, Gina
EVIDENCE, NCT06646341: EMVI as a Determinant of Metastasis in Colorectal Cancer

Recruiting
N/A
100
Europe
Imperial College London
Colo-rectal Cancer
12/25
12/27
DOCUMAS, NCT02579278: Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

Recruiting
N/A
100
Europe
Blood sample (mrEMVI positive patient), Blood sample (mrEMVI negative patient), Two blood samples are taken from each patient with mrEMVI negative tumours post chemoradiotherapy. One pre-surgery and one during surgery from a peripheral vein.
Imperial College London
Cancer, Rectal Cancer
12/26
12/29
COMET, NCT03303547: Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits

Recruiting
N/A
200
Europe
MRI mapping to guide pathological sampling of extranodal tumour deposits
Imperial College London, Pelican Cancer Foundation
Adenocarcinoma of the Rectum
12/26
12/31
SERENADE, NCT02246634: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI

Recruiting
N/A
282
Europe
Diffusion Weighted MRI scan
Imperial College London, Pelican Cancer Foundation
Colorectal Neoplasms, Neoplasm Metastases, Hepatic Neoplasms
12/26
12/31
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
NCT02292641: Beyond TME Origins

Recruiting
N/A
383
Europe
New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery
Imperial College London, Pelican Cancer Foundation
Neoplasms, Adenocarcinoma, Carcinoma
12/26
12/31
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
PRESERVE, NCT04103372: Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery

Recruiting
N/A
200
Europe
MRI scan, Radiologist training
Imperial College London, Pelican Cancer Foundation, RM Partners West London Cancer Alliance
Rectal Cancer, Colo-rectal Cancer
12/26
12/31
Smith, Katherine M
ABX464-105, NCT05507203: ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Recruiting
3
612
Europe, Canada, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
03/25
04/25
ABTECT, NCT05535946: - Maintenance

Recruiting
3
1050
Europe, Canada, Japan, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
01/26
01/30
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
Falk, Stephen
HERIZON-GEA-01, NCT05152147 / 2021-000296-36: A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Recruiting
3
918
Europe, Canada, Japan, RoW
Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil
Jazz Pharmaceuticals, BeiGene, Ltd.
Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma
05/25
05/26
MOUNTAINEER-03, NCT05253651 / 2021-002672-40: A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Recruiting
3
400
Europe, Canada, Japan, US, RoW
tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil
Seagen Inc., Merck Sharp & Dohme LLC
Colorectal Neoplasms
08/25
04/28
SAFIR-ABC10, NCT05615818: Personalized Medicine for Advanced Biliary Cancer Patients

Recruiting
3
800
Europe
Futibatinib, Ivosidenib, Tibsovo, Zanidatamab, Trastuzumab, Zercepac, Neratinib, Nerlynx, Encorafenib, Braftovi, Binimetinib, Mektovi, Niraparib, Zejula, Cisplatin, Gemcitabine
UNICANCER, Cancer Research UK & UCL Cancer Trials Centre, Belgian Group of Digestive Oncology, National Cancer Institute, France, Cancer Research UK, Taiho Oncology, Inc., Servier, Zymeworks BC Inc., Accord Healthcare, Inc., Pierre Fabre Medicament
Biliary Tract Neoplasms
06/27
06/28
SCOPE2, NCT02741856 / 2015-001740-11: Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation

Recruiting
2/3
584
Europe
Carboplatin, Paclitaxel, Cisplatin, Capecitabine, Radiotherapy
Lisette Nixon, Cancer Research UK
Oesophageal Cancer
04/21
04/23
PRIMUS006, NCT06498518: A Trial of Gemcitabine, Pembrolizumab and IMM-101 as First Line Treatment in Patients With Metastatic Pancreatic Cancer

Recruiting
2
50
Europe
IMM-101, Pembrolizumab, Gemcitabine
Karen Carty, NHS Greater Glasgow and Clyde, University of Glasgow
Neoplasms Pancreatic
06/27
12/27
PRIMUS 001, NCT04151277 / ISRCTN75002153 / 2016-004155-67: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer

Recruiting
2
500
Europe
FOLFOX-A, Gemcitabe and Abraxane, G-CSF
Judith Dixon-Hughes, NHS Greater Glasgow and Clyde, University of Glasgow
Neoplasms Pancreatic
12/25
01/26
NCT04161417: Precision-Panc Master Protocol: Personalising Treatment for Pancreatic Cancer

Recruiting
N/A
2500
Europe
Patients with suspected or confirmed pancreatic cancer will be be asked to provide biopsy material for molecular profiling
Judith Dixon-Hughes, Cancer Research UK, NHS Greater Glasgow and Clyde
Neoplasms Pancreatic
12/25
12/25
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
Person, Contact
PATCH, NCT00303784 / 2005-001030-33: Prostate Adenocarcinoma TransCutaneous Hormones

Recruiting
3
2200
Europe
Goserelin, Zoladex, Estradiol, FemSeven
University College, London, Medical Research Council
Anemia, Cardiovascular Complications, Hot Flashes, Osteoporosis, Prostate Cancer
08/21
08/21
UKALL14, NCT01085617 / 2009-012717-22: Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Active, not recruiting
3
1033
NA
palifermin, rituximab, cyclophosphamide, cytarabine, daunorubicin hydrochloride, etoposide, fludarabine phosphate, imatinib mesylate, melphalan, mercaptopurine, methotrexate, nelarabine, pegaspargase, vincristine sulfate, allogeneic hematopoietic stem cell transplantation, total-body irradiation
University College, London
Leukemia, Mucositis, Oral Complications
12/24
12/25
STAMPEDE, NCT00268476: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy

Active, not recruiting
2/3
11992
Europe
Celecoxib, Celebrex, Docetaxel, Taxotere, Prednisolone, Prednisone, ADT, Androgen Deprivation Therapy, Zoledronic Acid, Zometa, Abiraterone, Zytiga, Radiotherapy to the prostate, RT, Enzalutamide, Xtandi, Metformin, Metformin Hydrochloride, Transdermal Oestradiol, Progynova TS
Medical Research Council
Prostate Cancer
03/26
12/30
NCT00589017: Tamoxifen in Treating Patients With Metastatic Bladder Cancer That Did Not Respond to Previous Chemotherapy

Recruiting
2
75
US, Europe
tamoxifen citrate, immunohistochemistry staining method, laboratory biomarker analysis
Baylor College of Medicine
Bladder Cancer
07/10
 
NCT03412643: Study of Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab in HER2-Negative Breast Cancer Patients With Abnormal HER2 Signaling

Recruiting
2
64
US
Doxorubicin, Cyclophosphamide, Weekly Paclitaxel, Trastuzumab, Pertuzumab, Celcuity CELx HSF
NSABP Foundation Inc, Celcuity, LLC, Genentech, Inc.
HER2-negative Breast Cancer
10/23
10/23
PRISM, NCT03658525: Prostate Radiotherapy Integrated With Simultaneous MRI (The Study)

Recruiting
N/A
30
Europe
MR LINAC
Royal Marsden NHS Foundation Trust
Prostate Cancer
08/20
08/23
NCT06032663: Use of PET-MR in Head and Neck Cancer Patients - Diagnostic and Therapeutic Applications

Recruiting
N/A
10
Europe
PET-MRI
Sheffield Teaching Hospitals NHS Foundation Trust
Head and Neck Cancer
10/24
10/25
NCT01840293: Breast Cancer Proteomics and Molecular Heterogeneity

Recruiting
N/A
1780
Europe
Cancer Trials Ireland
Primary Breast Cancer, Recurrent/Metastatic Breast Cancer
12/29
01/38
Allen, Patrick
ABX464-105, NCT05507203: ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Recruiting
3
612
Europe, Canada, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
03/25
04/25
ABTECT, NCT05535946: - Maintenance

Recruiting
3
1050
Europe, Canada, Japan, US, RoW
ABX464, Obefazimod, Placebo
Abivax S.A.
Ulcerative Colitis
01/26
01/30
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Recruiting
2
268
Europe, Canada, Japan, US, RoW
TAK-279, Zasocitinib, Placebo
Takeda
Crohn's Disease
09/26
07/27
NCT06254950: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Recruiting
2
207
Europe, Canada, Japan, US, RoW
TAK-279, Zasocitinib, Placebo
Takeda
Ulcerative Colitis
09/26
08/27
Rashed, Khalid
ENRICH-AF, NCT03950076 / 2019-002075-33: EdoxabaN for IntraCranial Hemorrhage Survivors with Atrial Fibrillation

Active, not recruiting
4
948
Europe, Canada, US, RoW
Edoxaban, Lixiana, Savaysa, Non-anticoagulant medical therapy
Population Health Research Institute
Intracranial Hemorrhages, Atrial Fibrillation
04/26
10/26
TWIST, NCT03181360 / 2014-000096-80: Tenecteplase in Wake-up Ischaemic Stroke Trial

Recruiting
3
600
Europe, US, RoW
Tenecteplase, Metalyse, Control
University Hospital of North Norway, UiT The Arctic University of Norway, The Royal Norwegian Ministry of Health, Norwegian Health Association
Ischemic Stroke, Stroke, Acute
12/21
12/22
Higginson, Anthony
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Beaumont, Erica
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Parker, Chris
PATCH, NCT00303784 / 2005-001030-33: Prostate Adenocarcinoma TransCutaneous Hormones

Recruiting
3
2200
Europe
Goserelin, Zoladex, Estradiol, FemSeven
University College, London, Medical Research Council
Anemia, Cardiovascular Complications, Hot Flashes, Osteoporosis, Prostate Cancer
08/21
08/21
Curtis, Nathan
REMACS, NCT05219058: Reconstruction in Extended MArgin Cancer Surgery

Recruiting
N/A
236
Europe
Biological mesh reconstruction, Myocutaneous flap reconstruction, Primary closure reconstruction
University Hospital Southampton NHS Foundation Trust, Salisbury NHS Foundation Trust, University of Southampton, Dorset County Hospital NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, Mid Yorkshire Teaching NHS Trust, Newcastle-upon-Tyne Hospitals NHS Trust, University Hospitals Dorset NHS Foundation Trust, Somerset NHS Foundation Trust, Swansea Bay University Health Board, Portsmouth Hospitals NHS Trust, Hampshire Hospitals NHS Foundation Trust, Royal Devon and Exeter NHS Foundation Trust, Sussex Partnership NHS Foundation Trust, London North West Healthcare NHS Trust, Manchester University NHS Foundation Trust, NHS Greater Glasgow and Clyde, The Christie NHS Foundation Trust
Surgery--Complications, Pelvic Cancer, Abdominal Cancer, Quality of Life
09/26
01/28
Shah, Ahmar
NCT04763421: A Prospective, Single-Arm Multi-Center Study of the ENSEAL X1 Curved Jaw Tissue Sealer in Select Procedures

Completed
N/A
145
Europe, US
ENSEAL X1 Curved Jaw
Ethicon Endo-Surgery
Upper GI; Lower GI; Gynecological
08/23
09/23
Sophia, Rani
CHIEF PD, NCT04226248: CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)

Active, not recruiting
3
600
Europe
Rivastigmine Transdermal System, Placebo Transdermal System
University of Bristol, Royal United Hospitals Bath NHS Foundation Trust
Parkinson Disease
05/24
02/25
Lewis, Alison
CHIEF PD, NCT04226248: CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)

Active, not recruiting
3
600
Europe
Rivastigmine Transdermal System, Placebo Transdermal System
University of Bristol, Royal United Hospitals Bath NHS Foundation Trust
Parkinson Disease
05/24
02/25
Broadley, Andrew
EASY-AS, NCT04204915: The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study

Recruiting
N/A
2844
Europe, RoW
Aortic valve replacement
University of Leicester, University of Auckland, New Zealand, University Hospitals, Leicester, The University of Western Australia
Aortic Stenosis
04/31
04/31
Panayotova, Rosica
EASY-AS, NCT04204915: The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study

Recruiting
N/A
2844
Europe, RoW
Aortic valve replacement
University of Leicester, University of Auckland, New Zealand, University Hospitals, Leicester, The University of Western Australia
Aortic Stenosis
04/31
04/31

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