| Fan, Song |
REDUCTION-I, NCT05582265: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 3 | 537 | RoW | Tislelizumab（neoadjuvant）, Cisplatin （neoadjuvant）, Nab-paclitaxel （neoadjuvant）, Surgical resection, Cisplatin（adjuvant）, Tislelizumab（adjuvant）, Radiation, Carboplatin (neoadjuvant）, Carboplatin (adjuvant） | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Zhongshan People's Hospital, Guangdong, China, Shenzhen Sixth People's Hospital | Head and Neck Squamous Cell Carcinomas | 10/28 | 10/30 | | |
NCT04825938: Neoadjuvant Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated Salivary Gland Malignant Neoplasms |
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| Not yet recruiting | 2 | 15 | RoW | Toripalimab , Carboplatin, Nab-paclitaxel | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Salivary Gland Malignant Neoplasms, Salivary Gland Tumors | 06/22 | 06/27 | | |
OC-001, NCT04718415: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma |
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| Active, not recruiting | 2 | 51 | RoW | sintilimab, paclitaxel, carboplatin, Surgical resection | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Oral Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma | 01/23 | 01/27 | | |
NCT05000892: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Untreated Salivary Gland Malignant Neoplasms |
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| Recruiting | 2 | 15 | RoW | Sintilimab , Carboplatin, Nab-paclitaxel | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Salivary Gland Malignant Neoplasms, Salivary Gland Tumors | 06/23 | 10/27 | | |
NCT05724329: Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01) |
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| Active, not recruiting | 2 | 24 | RoW | Tislelizumab + Dasatinib + Quercetin (neoadjuvant), surgery, Tislelizumab + Dasatinib + Quercetin (adjuvant) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinomas | 04/24 | 08/28 | | |
NCT05098119: Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002) |
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| Recruiting | 2 | 43 | RoW | Sintilimab, Nab-paclitaxel, Carboplatin, Surgical resection, Sintilimab | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Oral Cavity Squamous Cell Carcinoma, Oral Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma | 09/24 | 09/28 | | |
NCT04807140: Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002) |
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| Recruiting | 2 | 57 | RoW | Toripalimab, nab-paclitaxel, carboplatin, Toripalimab, Surgical resection | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinoma | 12/23 | 01/27 | | |
NCT06323369: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 2 | 154 | RoW | Tislelizumab（neoadjuvant）, Cisplatin （neoadjuvant）, Nab-paclitaxel （neoadjuvant）, Surgical resection, Cisplatin（adjuvant）, Tislelizumab（adjuvant）, Radiation, Carboplatin（neoadjuvant）, Carboplatin（adjuvant） | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinoma | 03/29 | 09/29 | | |
NCT04992559: A Study of Toripalimab as Consolidation Therapy After Postoperative Chemoradiotherapy in HNSCC |
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| Recruiting | 2 | 41 | RoW | Consolidation Toripalimab | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinomas | 12/24 | 05/27 | | |
NCT05924984: Prospective Diagnostic Study on Perforator Localization of Anterolateral Thigh Flap With Perforator Locator |
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| Completed | N/A | 82 | RoW | perforator locator, color Doppler ultrasound | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Blood Vessel Perforation | 03/24 | 04/24 | | |
NCT06277687: Exploratory Study on the Application of Virtual Augmented Reality Combined With Finder in Preoperative Anterolateral Thigh Flap Perforator Positioning |
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| Completed | N/A | 24 | RoW | Virtual Augmented Reality Combined With Finder, Color Doppler ultrasound | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Blood Vessel Perforation | 07/24 | 07/24 | | |
NCT06576180: Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma |
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| Recruiting | N/A | 306 | RoW | Carboplatin（ neoadjuvant）, Paclitaxel （neoadjuvant）, Anti-PD-1 Drugs, Surgical resection | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinoma | 09/24 | 09/26 | | |
NCT06575322: Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma |
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| Recruiting | N/A | 302 | RoW | Carboplatin（ neoadjuvant）, Paclitaxel （neoadjuvant）, Anti-PD-1 Drugs, Surgical resection | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Head and Neck Squamous Cell Carcinoma | 09/26 | 03/27 | | |
