| Wang, Yilong |
PERFORM, NCT05583266: Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease |
|
|
| Not yet recruiting | 4 | 80 | RoW | Pentoxifylline sustained-release tablets, Pentoxifylline sustained-release tablets placebo | Beijing Tiantan Hospital, CSPC Ouyi Pharmaceutical Co., Ltd. | Cerebral Small Vessel Diseases | 03/23 | 03/24 | | |
NCT05578521: CerebrAlcare Pills on CereBral Small VesseL DiseasE（CABLE） |
|
|
| Active, not recruiting | 4 | 114 | RoW | Cerebralcare pills, Cerebralcare pills placebo | Beijing Tiantan Hospital, Tasly Pharmaceutical Group Co., Ltd | Cerebral Small Vessel Diseases | 12/23 | 03/24 | | |
STRATEGY, NCT05310968: Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction |
|
|
| Recruiting | 4 | 970 | RoW | Tirofiban hydrochloride sodium chloride injection, Tirofiban hydrochloride sodium chloride injection placebo, Aspirin | Beijing Tiantan Hospital, GrandPharma (China) Co., Ltd. | Branch Atheromatous Disease | 06/24 | 09/24 | | |
| Completed | 3 | 4810 | RoW | Early antihypertensive treatment, Delayed antihypertensive treatment | Tulane University, Beijing Tiantan Hospital, Soochow University | Acute Ischemic Stroke | 10/22 | 01/23 | | |
| Active, not recruiting | 3 | 6100 | RoW | Intensive antiplatelet, Dual antiplatelet, Standard antiplatelet, Aspirin, Immediate high-intensity statin, Immediate Atorvastatin, Delayed high-intensity statin, Delayed Atorvastatin | Beijing Tiantan Hospital, Ministry of Science and Technology of the People's Republic of China | Acute Stroke, Transient Ischemic Attack | 01/23 | 10/23 | | |
EMPHASIS, NCT05836740: Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke |
|
|
| Recruiting | 3 | 1672 | RoW | Minocycline hydrochloride capsule, Placebo capsules of Minocycline hydrochloride capsules | Beijing Tiantan Hospital, NeuroDawn Pharmaceutical Co., Ltd. | Ischemic Stroke, Acute | 03/24 | 10/24 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
|
|
| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
ESPRIT, NCT05836753: Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy |
|
|
| Recruiting | 2 | 120 | RoW | Sarecycline Tablet, Placebo tablets of Sarecycline tablets | Beijing Tiantan Hospital, NeuroDawn Pharmaceutical Co., Ltd. | Ischemic Stroke, Acute | 11/23 | 12/23 | | |
NCT06138834: EFfects of Y-6 SUblingual Tablets foR PaTients With AcUte Ischemic StRokE (FUTURE) |
|
|
| Not yet recruiting | 2 | 300 | NA | Low-dose Y-6 sublingual tablets, High-dose Y-6 sublingual tablets, Low-dose Cilostazol, High-dose Cilostazol, Placebo | Beijing Tiantan Hospital, NeuroDawn Pharmaceutical Co., Ltd. | Acute Ischemic Stroke, Large Vessel Occlusion, Reperfusion | 11/24 | 01/25 | | |
CRYSTAL, NCT05836766: Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients With Acute Ischemic Stroke With Large Vessel Occlusion |
|
|
| Recruiting | 2 | 120 | RoW | Y-6 sublingual tablets, Placebo tablets of Y-6 sublingual tablet | Beijing Tiantan Hospital, NeuroDawn Pharmaceutical Co., Ltd. | Acute Ischemic Stroke, Reperfusion, Large Vessel Occlusion | 07/24 | 08/24 | | |
| Not yet recruiting | 2 | 192 | RoW | Aleeto, Placebo | Beijing Tiantan Hospital | Acute Ischemic Stroke | 11/25 | 01/26 | | |
| Not yet recruiting | 2 | 328 | RoW | Estradiol Gel, Estradiol Placebo Gel, Progesterone Soft Capsule, Progesterone Placebo Soft Capsule | Beijing Tiantan Hospital | Cerebral Small Vessel Diseases, Postmenopausal Symptoms, Mild Cognitive Impairment, White Matter Hyperintensity | 06/25 | 10/25 | | |
| Not yet recruiting | 1 | 24 | RoW | Aleeto, intravenous injection, intrathecal injection | Beijing Tiantan Hospital | Amyotrophic Lateral Sclerosis | 10/24 | 10/24 | | |
NCT05903690: Safety and Tolerability of RAG-17 in the Treatment of Amyotrophic Lateral Sclerosis Patients With SOD1 Gene Mutation |
|
|
| Enrolling by invitation | 1 | 6 | RoW | RAG-17 | Beijing Tiantan Hospital, Ractigen Therapeutics | Gene Mutation | 02/24 | 02/24 | | |
NCT06596681: A Study of the Safety and Tolerability of GA in the Treatment of Patients with Refractory Neuropathic Pain |
|
|
| Not yet recruiting | 1 | 6 | NA | GA+clozapine | Beijing Tiantan Hospital | Pain, Intractable | 12/25 | 06/26 | | |
| Not yet recruiting | 1 | 12 | RoW | Tofacitinib tablets | Beijing Tiantan Hospital, Turing-Darwin Laboratory; West Institute of Computing Technology, Chongqing, China | Amyotrophic Lateral Sclerosis | 12/25 | 06/26 | | |
NCT06556394: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects With Amyotrophic Lateral Sclerosis (ALS) With Superoxide Dismutase Type 1 (SOD1) Gene Mutation |
|
|
| Recruiting | 1 | 32 | RoW | RAG-17, Placebo | Ractigen Therapeutics. | Amyotrophic Lateral Sclerosis | 02/26 | 04/26 | | |
SPRITE, NCT06765733: The Study of Safety and Preliminary Efficacy of Aleeto in Patients with MultIple System Atrophy |
|
|
| Not yet recruiting | 1 | 20 | RoW | Aleeto | Beijing Tiantan Hospital | Multiple System Atrophy - Parkinsonian Subtype (MSA-P), Multiple System Atrophy, MSA | 08/25 | 04/26 | | |
| Active, not recruiting | N/A | 100 | RoW | | Beijing Tiantan Hospital | Cerebral Small Vessel Diseases, Hereditary | 07/27 | 07/27 | | |
NCT03703635: Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis |
|
|
| Active, not recruiting | N/A | 512 | RoW | intracranial balloon angioplasty, aggressive medical management | Ministry of Science and Technology of the People´s Republic of China | Intracranial Artery Stenosis | 05/23 | 05/25 | | |
NCT05849805: Y-3 Injection Through Skull Bone Marrow in the Treatment of Acute Malignant Middle Cerebral Artery Infarction (SOLUTION) |
|
|
| Completed | N/A | 20 | RoW | Intracalvaria bone marrow injection, Conventional treatment | Beijing Tiantan Hospital | Stroke, Acute Ischemic | 11/23 | 01/24 | | |
SOLUTION-2, NCT06374667: The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction |
|
|
| Recruiting | N/A | 134 | RoW | Y-3 ICO injection, Y-3 intravenous injection, Conventional treatment | yilong Wang | Stroke, Acute Ischemic, Blood-Brain Barrier | 03/26 | 03/27 | | |
| Recruiting | N/A | 3500 | RoW | Without any intervention | Beijing Tiantan Hospital, Beijing Daxing District People Hospital | Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders, Cardiovascular Diseases, Population | 03/32 | 10/32 | | |
| Not yet recruiting | N/A | 1000 | RoW | Amyotrophic Lateral Sclerosis | yilong Wang | Amyotrophic Lateral Sclerosis | 12/24 | 12/24 | | |
MODEST, NCT06077305: A Registry Study of Microcirculation Disorder After Cerebral Small Vessel Disease and Ischemic Stroke |
|
|
| Not yet recruiting | N/A | 20000 | RoW | | Beijing Tiantan Hospital | Cerebral Small Vessel Diseases, Ischemic Stroke | 10/26 | 12/26 | | |
| Recruiting | N/A | 200 | RoW | | Beijing Tiantan Hospital | X-linked Adrenoleukodystrophy | 12/28 | 12/28 | | |
| An, Yachen |
SOLUTION-2, NCT06374667: The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction |
|
|
| Recruiting | N/A | 134 | RoW | Y-3 ICO injection, Y-3 intravenous injection, Conventional treatment | yilong Wang | Stroke, Acute Ischemic, Blood-Brain Barrier | 03/26 | 03/27 | | |
