Orvain, Corentin |
AVAJAK, NCT05198960: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms |
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| Recruiting | 3 | 1308 | Europe | Direct Oral Anticoagulants, Low-dose aspirin | University Hospital, Brest | Polycythemia Vera, Essential Thrombocythemia, Prefibrotic/Early Primary Myelofibrosis, JAK2 V617F, High-risk Patients | 07/27 | 07/27 | | |
NCT05753384: Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System |
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| Recruiting | 3 | 140 | Europe | treatment of TKI in CML | Poitiers University Hospital | Tyrosine Kinase Inhibitors, Chronic Myeloid Leukemia | 12/28 | 12/29 | | |
| Recruiting | 1/2 | 70 | Europe, Canada, Japan, US, RoW | DSP-5336 | Sumitomo Pharma America, Inc. | Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute | 01/25 | 02/25 | | |
BioScoreSMP, NCT03869476: Pilot Study for the Development of a Diagnostic Score to Differentiate Myeloproliferative Neoplasms. |
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| Completed | N/A | 133 | Europe | Non-invasive diagnosis score | University Hospital, Angers | Myeloproliferative Disorder, Essential Thrombocythemia, Primary Myelofibrosis, Prefibrotic Stage, Primary Myelofibrosis, Fibrotic Stage | 01/24 | 01/24 | | |
PHEMOP, NCT06361641: Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes |
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| Recruiting | N/A | 50 | Europe | Monocytes signatures in myeloproliferative neoplasms at diagnosis | University Hospital, Angers | Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis | 10/25 | 10/27 | | |
NCT06377579: OBServatory of Compassionate Use of IVOsidenib in France for Patients with Acute Myeloid Leukemia |
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| Recruiting | N/A | 250 | Europe | | French Innovative Leukemia Organisation, Acute Leukemia French Association | AML, Adult | 12/24 | 03/25 | | |
ALHERT, NCT06409767: Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation. |
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| Not yet recruiting | N/A | 2224 | Europe | Real-time calculation of the NEWS with ICU admission if NEWS ≥ 7. | University Hospital, Angers | Leukemia, Lymphoma, Multiple Myeloma | 10/27 | 01/28 | | |
ADNEMIA, NCT06075888: Metagenomic Sequencing for the Identification of Pathogens in Febrile Neutropenic Patients |
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| Recruiting | N/A | 200 | Europe | Metagenomic diagnosis (mNGS, DISQVER) | Poitiers University Hospital, Noscendo | Immunodepressed Patients (Hemato-oncology) | 01/25 | 01/25 | | |
| Not yet recruiting | N/A | 50 | Europe | Clonal architecture determination | University Hospital, Angers | Myelofibrosis | 03/25 | 03/29 | | |
MOLAM, NCT04931992: Outcome of Patients With CBF and/or NPM1-mutated AML in First Molecular Relapse. |
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| Recruiting | N/A | 100 | Europe | No intervention | University Hospital, Angers | Acute Myeloid Leukemia | 12/21 | 12/21 | | |
Bescond, Charles |
NCT01976182: Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia |
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| Completed | 2 | 166 | Europe | Methotrexate, Cyclophosphamide | Rennes University Hospital | Large Granular Lymphocytes Leukemia | 02/24 | 10/24 | | |
PHEMOP, NCT06361641: Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes |
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| Recruiting | N/A | 50 | Europe | Monocytes signatures in myeloproliferative neoplasms at diagnosis | University Hospital, Angers | Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis | 10/25 | 10/27 | | |
| Not yet recruiting | N/A | 50 | Europe | Clonal architecture determination | University Hospital, Angers | Myelofibrosis | 03/25 | 03/29 | | |
GOUBAND, Agathe |
PHEMOP, NCT06361641: Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes |
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| Recruiting | N/A | 50 | Europe | Monocytes signatures in myeloproliferative neoplasms at diagnosis | University Hospital, Angers | Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis | 10/25 | 10/27 | | |