UO Ematologia e Trapiano di Midollo - Ist. Scientifico Ospedale San Raffaele Trials

UO Ematologia e Trapiano di Midollo - Ist. Scientifico Ospedale San Raffaele	Welcome, Profile Billing Logout

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ciceri, Fabio

PhALLCON, NCT03589326 / 2018-000397-30: A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

	Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Sep 2019 - Sep 2019: Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Initiation of new trial in Ph+ ALL
	Jul 2018 - Jul 2018: Initiation of new trial in Ph+ ALL

Active, not recruiting

245

Europe, Canada, Japan, US, RoW

Ponatinib, Iclusig, Imatinib, Gleevec, Vincristine, Dexamethasone, Cytarabine, Methotrexate, Prednisone

Takeda

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

08/22

07/27

NCT04168502 / 2019-003871-20: Gemtuzumab Chemotherapy MRD Levels; Adult Untreated, de Novo, Fav Interm Risk AML

Recruiting

414

Europe

Gemtuzumab Ozogamicin

Gruppo Italiano Malattie EMatologiche dell'Adulto, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus, Pfizer S.R.L.

Acute Myeloid Leukemia

04/25

04/27

ARES, NCT04769895 / 2021-001841-11: MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients

Active, not recruiting

Europe

MaaT013

MaaT Pharma, MaaT Pharma

Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD

11/24

11/25

ACROBAT, NCT04184505 / 2019-003997-25: Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS

Recruiting

274

Europe

Azacitidine, AZA, Standard Chemotherapy, STD CHT, Allogeneic stem cell transplantation, HSCT

Gruppo Italiano Malattie EMatologiche dell'Adulto, AIFA - Italian Medicines Agency, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus

High-risk MDS

03/26

NCT03250338 / 2017-001600-29: Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Recruiting

322

Europe, Canada, US

Crenolanib, Crenolanib besylate, Cytarabine, Mitoxantrone, Placebo Oral Tablet, Fludarabine, Idarubicin, G-CSF

Arog Pharmaceuticals, Inc.

Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations

10/24

ALL2418, NCT03610438 / 2018-003006-32: Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Recruiting

Europe

Inotuzumab Ozogamicin (IO)

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Lymphoid Leukemia

11/22

NCT04475731 / 2020-003912-28: Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse

Active, not recruiting

Europe

Ponatinib

Gruppo Italiano Malattie EMatologiche dell'Adulto, Incyte Biosciences International Sàrl, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus

Philadelphia-Positive ALL, Acute Lymphoblastic Leukemia, in Relapse

11/24

XCGD-MOBI, NCT03055247 / 2015-002356-27: Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD

Recruiting

Europe

Ibuprofen, Myelostim, Mozobil

IRCCS San Raffaele, Fondazione Telethon

Chronic Granulomatous Disease X-linked (X-CGD)

07/23

PENTALLO, NCT03494959: Pentaglobin in CRE and PA Neutropenic Infections

Active, not recruiting

120

Europe

Pentaglobin

Gruppo Italiano Trapianto di Midollo Osseo

Septic Shock

05/24

05/25

V-FIRST, NCT03455504 / 2018-000392-33: Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia

Active, not recruiting

124

Europe

Venetoclax

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Myeloid Leukemia

01/25

ReSET-02, NCT05768035 / 2022-002530-14: Safety and Efficacy of SMART101 in Adult Patients With Hematological Malignancies After Haploidentical HSCT With Post-transplant Cyclophosphamide

Recruiting

1/2

Europe

Allogeneic T cell progenitors, cultured ex-vivo, SMART101

Smart Immune SAS, SMART IMMUNE

Hematological Malignancies

07/25

07/26

VAX4FRAIL, NCT04848493: National Project on Vaccines, COVID-19 and Frail Patients

Recruiting

N/A

1300

Europe

COVID-19 vaccines

Azienda Unità Sanitaria Locale Reggio Emilia, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Istituto Clinico Humanitas, IRCCS San Raffaele, Regina Elena Cancer Institute, Istituto Nazionale per le Malattie Infettive "Lazzaro Spallanzani" IRCCS, University of Roma La Sapienza, Fondazione IRCCS Policlinico San Matteo di Pavia, Istituti Fisioterapici Ospitalieri, Istituto Tumori Giovanni Paolo II, BARI, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy, IRCCS Azienda Ospedaliero-Universitaria di Bologna

COVID-19, Solid Tumor, Hematologic Diseases, Neurologic Disorder, Rheumatic Diseases

07/21

04/22

MPN-COVID, NCT04385160: Myeloproliferative Neoplasms (MPN) and COVID-19

Recruiting

N/A

552

Europe, US, RoW

Fondazione per la Ricerca Ospedale Maggiore, European Leukemia Net

Myeloproliferative Neoplasm, COVID

02/22

08/22

NCT04352556: COVID19-hematological Malignancies: the Italian Hematology Alliance

Recruiting

N/A

250

Europe

Ospedale di Circolo - Fondazione Macchi

SARS-CoV-2 Infection, Hematological Malignancies

10/22

COVID-BioB, NCT04318366: COVID-19 Patients Characterization, Biobank, Treatment Response and Outcome Predictor

Recruiting

N/A

6000

Europe

Observational Study

Università Vita-Salute San Raffaele

Coronavirus Infections

03/26

NCT03751917: Long-term Safety Study of Arsenic Trioxide in Newly Diagnosed, Low-to-intermediate Risk Acute Promyelocytic Leukemia

Recruiting

N/A

100

Europe

Arsenic Trioxide, ATRA+ATO

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Promyelocytic Leukemia

12/24

INTHEMA, NCT04298892: Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies

Recruiting

N/A

2000

Europe

clinical data and sample collection

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori, Azienda Unità Sanitaria Locale della Romagna

Haematologic Disease, Haematological Malignancy

02/25

GITMO-RELAPSE, NCT05124288: Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways

Recruiting

N/A

500

Europe

Observations on Relapsed AML Allogeneic Transplanted patients

Ciceri Fabio, Gruppo Italiano Trapianto di Midollo Osseo, Associazione Italiana per la Ricerca sul Cancro

Acute Myeloid Leukemia, in Relapse

12/26

06/27

Gucciari, Elena

No trials found

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ciceri, Fabio

PhALLCON, NCT03589326 / 2018-000397-30: A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia

	Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Sep 2019 - Sep 2019: Data from PhALLCON Study for newly diagnosed Ph+ ALL at SOHO 2020
	Initiation of new trial in Ph+ ALL
	Jul 2018 - Jul 2018: Initiation of new trial in Ph+ ALL

Active, not recruiting

245

Europe, Canada, Japan, US, RoW

Ponatinib, Iclusig, Imatinib, Gleevec, Vincristine, Dexamethasone, Cytarabine, Methotrexate, Prednisone

Takeda

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)

08/22

07/27

NCT04168502 / 2019-003871-20: Gemtuzumab Chemotherapy MRD Levels; Adult Untreated, de Novo, Fav Interm Risk AML

Recruiting

414

Europe

Gemtuzumab Ozogamicin

Gruppo Italiano Malattie EMatologiche dell'Adulto, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus, Pfizer S.R.L.

Acute Myeloid Leukemia

04/25

04/27

ARES, NCT04769895 / 2021-001841-11: MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients

Active, not recruiting

Europe

MaaT013

MaaT Pharma, MaaT Pharma

Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD

11/24

11/25

ACROBAT, NCT04184505 / 2019-003997-25: Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS

Recruiting

274

Europe

Azacitidine, AZA, Standard Chemotherapy, STD CHT, Allogeneic stem cell transplantation, HSCT

Gruppo Italiano Malattie EMatologiche dell'Adulto, AIFA - Italian Medicines Agency, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus

High-risk MDS

03/26

NCT03250338 / 2017-001600-29: Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Recruiting

322

Europe, Canada, US

Crenolanib, Crenolanib besylate, Cytarabine, Mitoxantrone, Placebo Oral Tablet, Fludarabine, Idarubicin, G-CSF

Arog Pharmaceuticals, Inc.

Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations

10/24

ALL2418, NCT03610438 / 2018-003006-32: Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia

Recruiting

Europe

Inotuzumab Ozogamicin (IO)

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Lymphoid Leukemia

11/22

NCT04475731 / 2020-003912-28: Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse

Active, not recruiting

Europe

Ponatinib

Gruppo Italiano Malattie EMatologiche dell'Adulto, Incyte Biosciences International Sàrl, Fondazione GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Franco Mandelli Onlus

Philadelphia-Positive ALL, Acute Lymphoblastic Leukemia, in Relapse

11/24

XCGD-MOBI, NCT03055247 / 2015-002356-27: Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD

Recruiting

Europe

Ibuprofen, Myelostim, Mozobil

IRCCS San Raffaele, Fondazione Telethon

Chronic Granulomatous Disease X-linked (X-CGD)

07/23

PENTALLO, NCT03494959: Pentaglobin in CRE and PA Neutropenic Infections

Active, not recruiting

120

Europe

Pentaglobin

Gruppo Italiano Trapianto di Midollo Osseo

Septic Shock

05/24

05/25

V-FIRST, NCT03455504 / 2018-000392-33: Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia

Active, not recruiting

124

Europe

Venetoclax

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Myeloid Leukemia

01/25

ReSET-02, NCT05768035 / 2022-002530-14: Safety and Efficacy of SMART101 in Adult Patients With Hematological Malignancies After Haploidentical HSCT With Post-transplant Cyclophosphamide

Recruiting

1/2

Europe

Allogeneic T cell progenitors, cultured ex-vivo, SMART101

Smart Immune SAS, SMART IMMUNE

Hematological Malignancies

07/25

07/26

VAX4FRAIL, NCT04848493: National Project on Vaccines, COVID-19 and Frail Patients

Recruiting

N/A

1300

Europe

COVID-19 vaccines

COVID-19, Solid Tumor, Hematologic Diseases, Neurologic Disorder, Rheumatic Diseases

07/21

04/22

MPN-COVID, NCT04385160: Myeloproliferative Neoplasms (MPN) and COVID-19

Recruiting

N/A

552

Europe, US, RoW

Fondazione per la Ricerca Ospedale Maggiore, European Leukemia Net

Myeloproliferative Neoplasm, COVID

02/22

08/22

NCT04352556: COVID19-hematological Malignancies: the Italian Hematology Alliance

Recruiting

N/A

250

Europe

Ospedale di Circolo - Fondazione Macchi

SARS-CoV-2 Infection, Hematological Malignancies

10/22

COVID-BioB, NCT04318366: COVID-19 Patients Characterization, Biobank, Treatment Response and Outcome Predictor

Recruiting

N/A

6000

Europe

Observational Study

Università Vita-Salute San Raffaele

Coronavirus Infections

03/26

NCT03751917: Long-term Safety Study of Arsenic Trioxide in Newly Diagnosed, Low-to-intermediate Risk Acute Promyelocytic Leukemia

Recruiting

N/A

100

Europe

Arsenic Trioxide, ATRA+ATO

Gruppo Italiano Malattie EMatologiche dell'Adulto

Acute Promyelocytic Leukemia

12/24

INTHEMA, NCT04298892: Integrated Multiomics and Multilevel Characterization of Haematological Disorders and Malignancies

Recruiting

N/A

2000

Europe

clinical data and sample collection

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori, Azienda Unità Sanitaria Locale della Romagna

Haematologic Disease, Haematological Malignancy

02/25

Recruiting

N/A

500

Europe

Observations on Relapsed AML Allogeneic Transplanted patients

Ciceri Fabio, Gruppo Italiano Trapianto di Midollo Osseo, Associazione Italiana per la Ricerca sul Cancro

Acute Myeloid Leukemia, in Relapse

12/26

06/27

Gucciari, Elena

No trials found



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