| Rivera, Jessica |
NCT05421741: Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial |
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| Recruiting | 4 | 484 | US | Antibiotic coated intramedullary Nail, Local Gentamicin 560 Powder, Vancomycin 2gm Liquid, Standard Intramedullary Nail | Wake Forest University Health Sciences | Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture | 12/26 | 12/27 | | |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
NCT05766670: Intramedullary Calcium Sulfate Antibiotic Depot |
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| Recruiting | 3 | 497 | US | Vancomycin Hydrochloride, antibacterial prescription medicine, Gentamicin, injection is used to treat certain serious infections that are caused by bacteria such as meningitis, Standard Intramedullary Nail, metal rod that is inserted into the medullary cavity of a bone and across the fracture in order to provide a solid support for the fractured bone | Wake Forest University Health Sciences | Open tÃbia Fracture, Osteomyelitis Tibia, Tibial Fractures | 01/27 | 01/28 | | |
| Completed | N/A | 196 | US | Diagnostic Test, CT Scan, Fibroscan, Urine and Blood testing, HIV Anti-retroviral Background Therapy | Theratechnologies, Dacima Consulting, Medpace, Inc., Vanderbilt University Medical Center, Echosens | HIV, HIV-Infections, HIV-1-infection, HIV I Infection, HIV Lipodystrophy, HIV Infection Primary, HIV-Associated Lipodystrophy, HIV Disease Progression, Lipohypertrophy, Liver Diseases, NAFLD, NASH, Liver Fibrosis, Hepatic Fibrosis, Waist Circumference, BMI, Ectopic Fat, Liver Fat, Hepatic Steatosis | 10/23 | 10/23 | | |
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures |
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| Recruiting | N/A | 218 | US | Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only | Wake Forest University Health Sciences | Calcaneus Fracture | 12/26 | 12/26 | | |
| Recruiting | N/A | 144 | US | Single Implant Fixation, Dual Implant Fixation | Wake Forest University Health Sciences, United States Department of Defense | Articular Fractures | 12/26 | 12/27 | | |
| Natoli, Roman |
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation |
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| Recruiting | 3 | 250 | US | Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics | Major Extremity Trauma Research Consortium, United States Department of Defense | Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect | 09/25 | 09/26 | | |
NCT06420141: The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture |
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| Recruiting | N/A | 250 | US | | Indiana University, Roman Natoli, MD, PhD, Kelly M. Naugle, PhD | Neuropathic Pain | 03/27 | 12/27 | | |
COPE, NCT04274530: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial |
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| Recruiting | N/A | 1000 | Canada, US | Cognitive Behavioural Therapy, CBT | McMaster University, Orthopaedic Trauma Association, Canadian Institutes of Health Research (CIHR) | Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open | 08/25 | 08/25 | | |
NCT04028414: Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures |
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| Active, not recruiting | N/A | 450 | US | Early Weight Bearing | Major Extremity Trauma Research Consortium | Rehabilitation | 10/24 | 03/25 | | |
