University Medical Center Jena
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 11 Trials 
23 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lindig, Udo
INTEGRATEIIb, NCT04879368 / 2020-004617-12: RegoNivo vs Standard of Care Chemotherapy in AGOC

Active, not recruiting
3
450
Europe, Japan, US, RoW
Regorafenib, Stivarga, Nivolumab, Opdivo, Docetaxel, Taxotere, Paclitaxel, Abraxane, Irinotecan, Camptosar, Trifluridine/Tipracil, Lonsurf
Australasian Gastro-Intestinal Trials Group, Bayer, Bristol-Myers Squibb, University of Sydney, Academic and Community Cancer Research United, Taiwanese Cooperative Oncology Group, Frankfurter Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, National Cancer Center Hospital East, Syneos Health
Gastro-Oesophageal Cancer
06/25
06/26
NCT05008809: Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)

Recruiting
3
507
Europe
mFOLFOX6, Folinic acid, Oxaliplatin, 5-fluorouracil (FU), mFOLFOXIRI, Folinic acid, Oxaliplatin, 5-FU, Irinotecan, FOLFIRI, Folinic acid, 5-FU, CAPOX, Capecitaine, Oxaliplatin
Dominik Paul Modest, German Research Foundation, Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Colorectal Cancer
11/27
11/30
IMMUWIN, NCT04522544: Durvalumab and Tremelimumab in Combination With Either Y-90 SIRT or DEB-TACE for Intermediate Stage HCC

Recruiting
2
55
Europe
Tremelimumab, Durvalumab, Y-90 SIRT, DEB-TACE
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, AstraZeneca, Hannover Medical School
Hepatocellular Carcinoma Non-resectable, HCC
03/25
09/25
NCT04238637 / 2018-004778-81: Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)

Recruiting
2
50
Europe
Durvalumab, Other Name: MEDI4736, Tremelimumab, Study treatment
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, AstraZeneca
Intrahepatic Cholangiocarcinoma
12/25
12/25
NCT05174650 / 2020-004938-38: Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements

Active, not recruiting
2
27
Europe
Atezolizumab, Tecentriq, Derazantinib, ARQ 087
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, ROCHE Pharma AG, Basilea Pharmaceutica International Ltd.
Intrahepatic Cholangiocarcinoma
12/25
08/26
NCT06123468: Study Evaluating Treatment of Sacituzumab-govitecan for Patients With Metastatic Esophagogastric Adenocarcinoma

Active, not recruiting
1/2
56
Europe
Sacituzumab govitecan, Trodelvy
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, Gilead Sciences
Esophagogastric Adenocarcinoma
02/27
03/27
Akhter, Shahab A
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
08/26
08/26
Doenst, Torsten
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
08/26
08/26
PASTA, NCT04632095: Parasternal vs. Sternotomy Approach for Conventional Aortic Valve Replacement

Recruiting
N/A
50
Europe
Aortic valve replacement due to sternotomy, Aortic valve replacement due to parasternal right anterior mini-thoracotomy
Jena University Hospital, The German Heart Foundation
Aortic Valve Stenosis
03/22
11/22
NCT04142021: Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)

Recruiting
N/A
114
Europe
Coronary computed tomography angiography
National University of Ireland, Galway, Ireland, GE Healthcare, HeartFlow, Inc.
Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases
12/22
12/22
NCT05389631: Trifecta and Epic ViV Detailed Insights Into Management Strategies and Outcomes

Completed
N/A
76
Europe
no intervention
Helios Health Institute GmbH, Abbott
Aortic Valve Disease
12/23
12/23
NCT02387112: Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

Active, not recruiting
N/A
102
Europe
Early VAD implantation
German Heart Institute, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Helmholtz Zentrum München, University Medicine Greifswald, University of Göttingen
End Stage Heart Disease
03/24
12/24
ABT-CIP-10415, NCT06590467: Abbott Structural Heart Device Registry

Recruiting
N/A
2500
Europe
Amplatzer™ Occlusion Devices, Amplatzer Septal Occluder, Amplatzer Multi-fenestrated (Cribriform) Occluder, Amplatzer Duct Occluder, Amplatzer Piccolo Occluder, Amplatzer Muscular VSD Occluder, Amplatzer Post-Infarct VSD Occluder, Amplatzer Talisman, Amplatzer TorqVue Delivery System, Epic™ Surgical Tissue Heart Valve devices, EMAX, E200, ESP200, Sizer Set Model E2000, Sizer Set Model EMAX-1000, Replacement Holder Handles E2000-HA and E2000-HM
Abbott Medical Devices
Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale, PIVSD - Post Infarct Muscular Ventricular Septal Defect, Valvular Heart Disease
07/29
11/39
ROMA, NCT03217006: Randomization of Single vs Multiple Arterial Grafts

Active, not recruiting
N/A
4300
Europe, Canada, Japan, US, RoW
Single arterial graft, Multiple arterial grafting
Weill Medical College of Cornell University, National Heart, Lung, and Blood Institute (NHLBI), Canadian Institutes of Health Research (CIHR)
Coronary Artery Disease, Heart Diseases
06/27
01/30
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds

Recruiting
N/A
450
Europe, Canada, US
Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER
Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI)
Mitral Valve Regurgitation
11/28
11/30
HARVITA, NCT05931783: Randomized Comparison of Skeletonized Versus Pedicled Left Internal Thoracic Artery

Recruiting
N/A
1350
Europe
skeletonized harvesting technique, pedicled harvesting technique
Medical University Innsbruck
Coronary Artery Disease
10/28
10/31
NCT04124120: Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
N/A
2000
Europe, Canada, Japan, US, RoW
Single arterial graft, Multiple arterial grafting
Weill Medical College of Cornell University, New York Presbyterian Hospital, Sunnybrook Health Sciences Centre, Cedars-Sinai Medical Center, Columbia University, Duke University
Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
03/30
03/30
ARB-PMCF, NCT04761120: Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

Recruiting
N/A
550
Europe, US
Abbott SJM Rigid Saddle Ring, Abbott SJM Séguin Ring, Abbott SJM Tailor Ring, Abbott SJM Tailor Band
Abbott Medical Devices
Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
11/30
03/31
Krauspe, Sabine
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
08/26
08/26
Zwischenberger, Brittany
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
08/26
08/26
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds

Recruiting
N/A
450
Europe, Canada, US
Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER
Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI)
Mitral Valve Regurgitation
11/28
11/30
NCT04124120: Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
N/A
2000
Europe, Canada, Japan, US, RoW
Single arterial graft, Multiple arterial grafting
Weill Medical College of Cornell University, New York Presbyterian Hospital, Sunnybrook Health Sciences Centre, Cedars-Sinai Medical Center, Columbia University, Duke University
Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
03/30
03/30
Cristina, Ripoll
Terli-CKD, NCT06161766: Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease

Completed
N/A
490
Europe
terlipressin or noradrenalin plus albumin
University Hospital Freiburg, Jena University Hospital, Johannes Gutenberg University Mainz, University Hospital Muenster
Liver Cirrhosis, Hepato-Renal Syndrome, Chronic Kidney Diseases
12/24
12/24

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