United States, Tennessee St. Jude Children's Research Hospital
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 0 Trials 
11 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Karol, Seth E
NCT06289673: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Recruiting
4
850
US
Dexamethasone, Decadron, Vincristine, Vincristine Sulfate, Oncovin, Daunorubicin, Daunomycin, Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine), ITMHA, Methotrexate, MTX, Trexall®, Cytarabine, Cytosine arabinoside, Ara-C
St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia
05/34
05/39
APAL2020D, NCT05183035 / 2021-003212-11: Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Recruiting
3
98
Europe, Canada, Japan, US, RoW
Fludarabine, Cytarabine, Gemtuzumab Ozogamicin, Azacitidine, Venetoclax
LLS PedAL Initiative, LLC, Princess Maxima Center for Pediatric Oncology (European Sponsor), AbbVie, Roche-Genentech, EuPAL
Acute Myeloid Leukemia
02/27
04/31
NCT04401267: Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma

Active, not recruiting
2
51
US
Intensive Antihypertensive Therapy, Hypotensive Therapy, Conventional Antihypertensive Therapy, Symptom Survey, Survey, Semi-structured interview, Interview
St. Jude Children's Research Hospital, National Cancer Institute (NCI)
Hypertension, Osteonecrosis, Osteonecrosis Due to Drug
09/23
09/25
NCT06390319: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

Recruiting
2
100
US
Dexamethasone, Decadron, Hexadrol®, Vincristine, Vincristine Sulfate, Oncovin, Daunorubicin, Daunomycin, Calaspargase pegol, ASPARLAS, Dasatinib, Sprycel®, Venetoclax, Venclexta®, Bortezomib, Velcade®, Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine), IT MHA, Cyclophosphamide, Cytoxan®, Cytarabine, Ara-C, Cytosine arabinoside, Mercaptopurine, 6-MP, Nelarabine, Arranon, Atriance, Methotrexate, Trexall®, Thioguanine, 6-thioguanine, Tabloid®
St. Jude Children's Research Hospital, AbbVie
T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma, Mixed Phenotype Acute Leukemia
12/27
12/33
NCT06533748: Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma

Recruiting
2
128
US
Dexamethasone, Decadron, Hexadrol®, Vincristine, Vincristine Sulfate, Oncovin, Inotuzumab, Inotuzumab ozogamicin, BESPONSA®, Blinatumomab, BLINCYTO®, Dasatinib, Sprycel®, IT MHA, Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine), Cyclophosphamide, Cytoxan®, Cytarabine, Cytosine arabinoside, Ara-C, Methotrexate, MTX, Trexall®, 6-Mercaptopurine, Mercaptopurine, 6-MP, Calaspargase, ASPARLAS, Daunorubicin, Daunomycin, Thioguanine, 6-thioguanine, Tabloid®
St. Jude Children's Research Hospital, Pfizer, Amgen
Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
05/28
05/34
NCT05192889: Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

Active, not recruiting
1/2
35
US
Venetoclax, Venclextra®, ABT-199, Navitoclax, ABT-263, Dexamethasone, Decadron®, Hexadrol®, Dexameth®, Vincristine, Vincristine sulfate, Oncovin®, Calaspargase Pegol, Asparlas, Dasatinib, Sprycel®, Cytarabine, Ara-C, Cytosar-U®, Blinatumomab, Blincyto®, Methotrexate, MTX, Trexall®, amethopterin, Mercaptopurine, 6-MP, Purinethol®, Cyclophosphamide, Cytoxan®, Etoposide, VP-16, Vepesid®, Leucovorin, Folinic acid, Intrathecal Triples, ITMHA, methotrexate/hydrocortisone/cytarabine, Pegaspargase, Oncaspar®, PEG-asparaginase, PEG-L-asparaginase, Erwinia asparaginase, Erwinase®, Radiation, Irradiation
St. Jude Children's Research Hospital, AbbVie
Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia
06/24
03/25
NCT04501614 / 2019-002549-39: A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Terminated
1/2
11
Europe, US, RoW
Ponatinib, Chemotherapy Agents
Takeda, Takeda Development Center Americas, Inc.
Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)
12/23
07/24
CRSPA, NCT04195347: Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

Recruiting
1/2
42
US
CM4620, CM4620-IE
St. Jude Children's Research Hospital, CalciMedica, Inc.
Acute Pancreatitis
06/25
12/27
APAL2020SC, NCT04726241: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Recruiting
1/2
960
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection
LLS PedAL Initiative, LLC, Children's Oncology Group, National Cancer Institute (NCI)
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Juvenile Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome
12/26
12/26
SELCLAX, NCT04898894: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
1
42
US
Venetoclax, Venclextra®, ABT-199, Selinexor, KPT-330, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Fludarabine, Fludara®, Fludarabine phosphate, 2-fluoro-ara-AMP, Filgrastim, G-CSF, Methotrexate, MTX, amethopterin, Trexall®, methotrexate/hydrocortisone/cytarabine, ITMHA, Intrathecal triples
St. Jude Children's Research Hospital, Karyopharm Therapeutics Inc, AbbVie, Gateway for Cancer Research
Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia
07/23
06/27
PARPAML, NCT05101551: Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

Recruiting
1
34
US
Talazoparib, Talzenna, Topotecan, Hycamtin, Gemcitabine, Gemzar, Infugem
Norman J. Lacayo, Gateway for Cancer Research
Acute Myeloid Leukemia
03/26
03/26

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