Lucile Packard Children Hospital Stanford University
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 9 Trials 
9 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Fisher, Paul G
NCT02899715: Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma

Recruiting
1
30
US
Laboratory Biomarker Analysis, Panobinostat, Faridak, Farydak, LBH589, Pharmacological Study
National Cancer Institute (NCI)
Diffuse Intrinsic Pontine Glioma
10/19
 
NCT04196413: GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Recruiting
1
54
US
GD2 CAR T cells, Fludarabine, Cyclophosphamide
Crystal Mackall, MD, California Institute for Regenerative Medicine (CIRM), CureSearch, National Institutes of Health (NIH)
Glioma of Spinal Cord, Glioma of Brainstem
07/28
07/43
Monje, Michelle
NCT04201457: A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Active, not recruiting
1/2
57
US
Dabrafenib, Dabrafenib mesylate, Tafinlar, Trametinib, Trametinib dimethyl sulfoxide, Mekinist, Hydroxychloroquine, Plaquenil, Plaquinol, Toremonil, Ercoquinn
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI), American Lebanese Syrian Associated Charities
Low Grade Glioma (LGG) of Brain With BRAF Aberration, High Grade Glioma (HGG) of the Brain With BRAF Aberration, Low Grade Glioma of Brain With Neurofibromatosis Type 1
03/27
06/30
NCT02899715: Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma

Recruiting
1
30
US
Laboratory Biomarker Analysis, Panobinostat, Faridak, Farydak, LBH589, Pharmacological Study
National Cancer Institute (NCI)
Diffuse Intrinsic Pontine Glioma
10/19
 
PBTC-047, NCT02717455: Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

Completed
1
53
US
LBH589, Panobinostat
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI)
Glioma
02/22
03/24
NCT03389802: Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Active, not recruiting
1
32
US
APX005M treatment for recurrent or refractory primary malignant CNS tumor patients, APX005M treatment for newly diagnosed DIPG patients
Pediatric Brain Tumor Consortium, American Lebanese Syrian Associated Charities, Pyxis Oncology, Inc, Solving Kids' Cancer, Ty Louis Campbell Foundation, A Kids' Brain Tumor Cure Foundation, National Cancer Institute (NCI)
Glioblastoma Multiforme, High-grade Astrocytoma Not Otherwise Specified (NOS), CNS Primary Tumor, Not Otherwise Specified (NOS), Ependymoma, Not Otherwise Specified (NOS), Diffuse Intrinsic Pontine Gliomas (DIPG), Medulloblastoma
09/23
11/25
NCT04295759: INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Completed
1
13
US
INCB7839
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI), American Lebanese Syrian Associated Charities
Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, DIPG, High-grade Astrocytoma NOS, CNS Primary Tumor, NOS (Malignant Glioma)
12/23
12/24
NCT04196413: GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Recruiting
1
54
US
GD2 CAR T cells, Fludarabine, Cyclophosphamide
Crystal Mackall, MD, California Institute for Regenerative Medicine (CIRM), CureSearch, National Institutes of Health (NIH)
Glioma of Spinal Cord, Glioma of Brainstem
07/28
07/43
NCT05416554: Long-term Cognitive, Neuropsychiatric and Functional Outcomes in Adults Who Have Received Chimeric Antigen-Receptor T-Cell (CAR-T) Therapy for Aggressive Lymphoma at Stanford

Not yet recruiting
N/A
20
US
Neuropsychological testing
Stanford University
Non Hodgkin Lymphoma
12/26
12/27
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Fisher, Paul G
NCT02899715: Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma

Recruiting
1
30
US
Laboratory Biomarker Analysis, Panobinostat, Faridak, Farydak, LBH589, Pharmacological Study
National Cancer Institute (NCI)
Diffuse Intrinsic Pontine Glioma
10/19
 
NCT04196413: GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Recruiting
1
54
US
GD2 CAR T cells, Fludarabine, Cyclophosphamide
Crystal Mackall, MD, California Institute for Regenerative Medicine (CIRM), CureSearch, National Institutes of Health (NIH)
Glioma of Spinal Cord, Glioma of Brainstem
07/28
07/43
Monje, Michelle
NCT04201457: A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Active, not recruiting
1/2
57
US
Dabrafenib, Dabrafenib mesylate, Tafinlar, Trametinib, Trametinib dimethyl sulfoxide, Mekinist, Hydroxychloroquine, Plaquenil, Plaquinol, Toremonil, Ercoquinn
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI), American Lebanese Syrian Associated Charities
Low Grade Glioma (LGG) of Brain With BRAF Aberration, High Grade Glioma (HGG) of the Brain With BRAF Aberration, Low Grade Glioma of Brain With Neurofibromatosis Type 1
03/27
06/30
NCT02899715: Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma

Recruiting
1
30
US
Laboratory Biomarker Analysis, Panobinostat, Faridak, Farydak, LBH589, Pharmacological Study
National Cancer Institute (NCI)
Diffuse Intrinsic Pontine Glioma
10/19
 
PBTC-047, NCT02717455: Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

Completed
1
53
US
LBH589, Panobinostat
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI)
Glioma
02/22
03/24
NCT03389802: Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Active, not recruiting
1
32
US
APX005M treatment for recurrent or refractory primary malignant CNS tumor patients, APX005M treatment for newly diagnosed DIPG patients
Pediatric Brain Tumor Consortium, American Lebanese Syrian Associated Charities, Pyxis Oncology, Inc, Solving Kids' Cancer, Ty Louis Campbell Foundation, A Kids' Brain Tumor Cure Foundation, National Cancer Institute (NCI)
Glioblastoma Multiforme, High-grade Astrocytoma Not Otherwise Specified (NOS), CNS Primary Tumor, Not Otherwise Specified (NOS), Ependymoma, Not Otherwise Specified (NOS), Diffuse Intrinsic Pontine Gliomas (DIPG), Medulloblastoma
09/23
11/25
NCT04295759: INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Completed
1
13
US
INCB7839
Pediatric Brain Tumor Consortium, National Cancer Institute (NCI), American Lebanese Syrian Associated Charities
Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, DIPG, High-grade Astrocytoma NOS, CNS Primary Tumor, NOS (Malignant Glioma)
12/23
12/24
NCT04196413: GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

Recruiting
1
54
US
GD2 CAR T cells, Fludarabine, Cyclophosphamide
Crystal Mackall, MD, California Institute for Regenerative Medicine (CIRM), CureSearch, National Institutes of Health (NIH)
Glioma of Spinal Cord, Glioma of Brainstem
07/28
07/43
NCT05416554: Long-term Cognitive, Neuropsychiatric and Functional Outcomes in Adults Who Have Received Chimeric Antigen-Receptor T-Cell (CAR-T) Therapy for Aggressive Lymphoma at Stanford

Not yet recruiting
N/A
20
US
Neuropsychological testing
Stanford University
Non Hodgkin Lymphoma
12/26
12/27

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