| Tzovaras, George |
NCT05727007: CT and MRI in Preoperative Colon Cancer Staging |
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| Completed | N/A | 120 | Europe | MRI in colon cancer, CT in colon cancer | Larissa University Hospital, University of Thessaly | Colonic Neoplasms | 03/23 | 05/23 | | |
NCT05496491: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial |
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| Recruiting | N/A | 84 | Europe | Neoadjuvant Chemoradiotherapy, nCRT, Adjuvant Chemotherapy, AC, Consolidation Chemotherapy, CC | Larissa University Hospital | Rectal Neoplasms | 08/26 | 08/26 | | |
NCT05713903: Laparoscopic Versus Open Right Colectomy for Right Colon Cancer |
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| Recruiting | N/A | 114 | Europe | Laparoscopic right colectomy, Open right colectomy | Larissa University Hospital | Colon Cancer | 01/26 | 01/27 | | |
| Baloyiannis, Ioannis |
NCT05727007: CT and MRI in Preoperative Colon Cancer Staging |
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| Completed | N/A | 120 | Europe | MRI in colon cancer, CT in colon cancer | Larissa University Hospital, University of Thessaly | Colonic Neoplasms | 03/23 | 05/23 | | |
NCT05496491: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial |
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| Recruiting | N/A | 84 | Europe | Neoadjuvant Chemoradiotherapy, nCRT, Adjuvant Chemotherapy, AC, Consolidation Chemotherapy, CC | Larissa University Hospital | Rectal Neoplasms | 08/26 | 08/26 | | |
NCT05713903: Laparoscopic Versus Open Right Colectomy for Right Colon Cancer |
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| Recruiting | N/A | 114 | Europe | Laparoscopic right colectomy, Open right colectomy | Larissa University Hospital | Colon Cancer | 01/26 | 01/27 | | |
| Kotsakis, Athanasios |
JADE, NCT06256588: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma |
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| Recruiting | 3 | 864 | Europe, Canada, Japan, US, RoW | Dostarlimab, Placebo | GlaxoSmithKline | Neoplasms, Head and Neck | 05/28 | 07/29 | | |
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer |
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| Active, not recruiting | 3 | 866 | Europe, Japan, US, RoW | Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219 | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasms, Neoplasm Metastasis | 06/24 | 08/27 | | |
| Recruiting | 3 | 500 | Europe, Japan, US, RoW | JNJ-90301900 (NBTXR3), Functionalized hafnium oxide nanoparticles, NBTXR3, Cetuximab, Erbitux, Radiation Therapy | Johnson & Johnson Enterprise Innovation Inc., Nanobiotix SA | Locally Advanced Head and Neck Squamous Cell Carcinoma, Aged | 06/26 | 06/27 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
| Recruiting | 2 | 340 | Europe, Japan, US, RoW | Pembrolizumab, Dostarlimab, GSK4057190, Belrestotug, EOS884448, GSK4428859A, Nelistotug, GSK6097608 | GlaxoSmithKline, iTeos Therapeutics | Lung Cancer, Non-Small Cell | 10/25 | 10/28 | | |
| Recruiting | N/A | 675 | Europe | Implantable Cardioverter Defibrillator (ICD) insertion | University of Athens | Sudden Cardiac Death Due to Cardiac Arrhythmia, Dilated Cardiomyopathy | 05/25 | 05/25 | | |
NCT05496491: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial |
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| Recruiting | N/A | 84 | Europe | Neoadjuvant Chemoradiotherapy, nCRT, Adjuvant Chemotherapy, AC, Consolidation Chemotherapy, CC | Larissa University Hospital | Rectal Neoplasms | 08/26 | 08/26 | | |
| Bareka, Metaxia |
NCT06269770: Tapentadol vs Tramadol in Total Knee Arthroplasty |
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| Recruiting | 4 | 96 | Europe | Tapentadol, Tramadol | University of Thessaly | Total Knee Replacement, Post-operative Pain, Chronic Pain | 05/25 | 06/25 | | |
| Recruiting | N/A | 288 | Europe | Preoperative HbA1c | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, HbA1c | 09/21 | 11/21 | | |
| Recruiting | N/A | 288 | Europe | NLR, PLR | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio | 12/21 | 12/21 | | |
NCT04736303: The Impact of the Implementation of BIS on the Incidence of Postoperative Delirium |
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| Recruiting | N/A | 1400 | Europe | BIS | University of Thessaly | Postoperative Delirium | 12/22 | 04/23 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine, Remifentanil | University of Thessaly | Functional Endoscopic Sinus Surgery | 10/23 | 12/23 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine | University of Thessaly | Acute Kidney Injury, Dexmedetomidine, Endovascular Aortic Repair | 11/23 | 02/24 | | |
| Recruiting | N/A | 30 | Europe | ERAS | University of Thessaly | ERAS, Craniotomy | 05/24 | 07/24 | | |
| Koukoulis, Georgios |
NCT04679116: Laparoscopic vs Open Bilateral Inguinal Hernia Repair |
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| Recruiting | N/A | 100 | Europe | Laparoscopic bilateral inguinal hernia repair, Open bilateral inguinal hernia repair | General Hospital of Larissa | Inguinal Hernia Bilateral | 12/22 | 12/22 | | |
| Hajiioannou, Jiannis |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine, Remifentanil | University of Thessaly | Functional Endoscopic Sinus Surgery | 10/23 | 12/23 | | |
| Completed | N/A | 500 | Europe, US, RoW | Total Thyroidectomy | Aristotle University Of Thessaloniki | Medullary Thyroid Cancer | 04/24 | 04/24 | | |
| Zacharoulis, Dimitrios |
| Recruiting | N/A | 64 | Europe | | University of Thessaly | Venous Thromboembolism, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma | 09/24 | 10/24 | | |
| Not yet recruiting | N/A | 150 | Europe | Greek version of QoR-15 | IASO Thessalias | Postoperative Recovery, Quality of Recovery From Anaesthesia, PROMs, Validation Study, Cultural Adaptation | 02/25 | 02/25 | | |
NCT05518643: Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes |
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| Recruiting | N/A | 120 | Europe | ERAS protocol | University of Thessaly, IASO Thessalias, Larissa University Hospital | ERAS, Pancreas Cancer, Pancreas; Fistula, Delayed Gastric Emptying, Surgery-Complications, Pancreatic Hemorrhage, PROMs | 08/25 | 08/26 | | |
| Koumarianou, Anna |
GALAXIES Lung-301, NCT06472076: A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC) |
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| Recruiting | 3 | 1000 | Europe, Canada, Japan, RoW | Dostarlimab, Belrestotug, Pembrolizumab, Placebo | GlaxoSmithKline, iTeos Therapeutics | Lung Cancer, Non-Small Cell | 09/28 | 09/29 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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KROCUS, NCT05756153: A Study of GFH925 in Combination with Cetuximab in Previously Untreated Advanced NSCLC Harboring KRAS G12C Mutation |
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| Recruiting | 1/2 | 45 | Europe | GFH925, Cetuximab | Genfleet Therapeutics (Shanghai) Inc. | Advance Non-small Cell Lung Cancer | 03/25 | 08/25 | | |
| Recruiting | 1/2 | 68 | Europe, US, RoW | Elacestrant, Elacestrant dihydrochloride, RAD-1901, ER-306323, Orserdu, Abemaciclib, Verzenio | Stemline Therapeutics, Inc., Stemline Therapeutics, Inc | Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms, Breast Diseases, Central Nervous System Neoplasms, Brain Diseases, Central Nervous System Diseases | 12/25 | 12/25 | | |
NCT04064359: Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors |
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| Recruiting | 1 | 200 | Europe, US | OBT076, a CD205-directed antibody-drug conjugate, MEN1309 | Oxford BioTherapeutics Ltd | Solid Tumor | 12/26 | 12/27 | | |
| Zamagni, Claudio |
| Terminated | 3 | 23 | Europe | Exemestane, Mestane, Placebo oral tablet | Ente Ospedaliero Ospedali Galliera, Istituto Di Ricerche Farmacologiche Mario Negri, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Federation of Italian Cooperative Oncology Groups | Ovarian Cancer | 04/23 | 04/23 | | |
SALVOVAR, NCT06476184: Utility of Adjusting Chemotherapy Dose & Dosing Schedule with the SALVage Weekly Dose-dense Regimen in Patients with Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery |
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| Recruiting | 3 | 250 | Europe, Japan | Carboplatin, Paclitaxel | ARCAGY/ GINECO GROUP, Horizon 2020 - European Commission | Ovarian Cancer | 06/27 | 06/28 | | |
NCT02584478 / 2021-003871-32: Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) |
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| Active, not recruiting | 3 | 294 | Europe, US, RoW | AL3818, Anlotinib Hydrochloride, Anlotinib, Catequentinib, Paclitaxel, Pegylated Liposomal Doxorubicin (PLD), Topotecan, Daily Topotecan, Weekly Topotecan, Carboplatin, Paraplatin, Taxol | Advenchen Laboratories, LLC, Advenchen Laboratories, LLC | Endometrial Carcinoma, Ovarian Carcinoma, Fallopian Tube Carcinoma, Primary Peritoneal Carcinoma, Cervical Carcinoma | 10/24 | 12/24 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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ZEST, NCT04915755 / 2020-003973-23: Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease |
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| Active, not recruiting | 3 | 43 | Europe, Canada, Japan, US, RoW | Niraparib, Placebo | GlaxoSmithKline | Neoplasms, Breast | 06/24 | 12/25 | | |
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EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
| Active, not recruiting | 2 | 129 | Europe | carboplatin and paclitaxel followed by surgery | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Ovarian Cancer, Fallopian Tube Carcinoma, Peritoneal Carcinoma | 05/21 | 12/23 | | |
| Completed | 2 | 54 | Europe | Zoledronate, zoledronic acid, Atorvastatin 80mg, Standard neoadjuvant cht | Mario Negri Institute for Pharmacological Research, Associazione Italiana per la Ricerca sul Cancro | Triple Negative Breast Cancer | 06/21 | 07/23 | | |
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers |
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| Completed | 2 | 79 | Europe, Canada, US, RoW | Mirvetuximab soravtansine, MIRV, IMGN853 | AbbVie | Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer | 01/24 | 12/24 | | |
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NCT05266937: Atezolizumab Plus CArboplatin Plus Nab-paclitaxel |
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| Active, not recruiting | 2 | 49 | Europe | Atezolizumab,Paclitaxel, Carboplatin | Consorzio Oncotech | Metastatic Breast Cancer, Triple Negative Breast Cancer, PD-L1 Gene Mutation | 07/24 | 07/24 | | |
NCT06433219: Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302) |
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| Recruiting | 2 | 60 | Europe, US, RoW | Tuvusertib (M1774), M1774, VXc-400, VRT-1363004, substance code MSC2584415A, Niraparib, GSK3985771, MK-4827, Lartesertib (M4076), M4076, substance code MSC2585823A | EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany | Ovarian Cancer | 01/28 | 01/28 | | |
| Active, not recruiting | 2 | 393 | Europe | Trastuzumab and Pertuzumab (FDC SC) and T-DM1, Trastuzumab emtansine, Phesgo, Kadcyla | MedSIR, Hoffmann-La Roche | Early Breast Cancer | 09/25 | 03/28 | | |
GALENO 1, NCT04474951: Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies |
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| Recruiting | N/A | 60 | Europe | Stinging Nettle, Peppermint | Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi | Breast Cancer, Gynecologic Cancer | 03/21 | 09/21 | | |
| Recruiting | N/A | 102 | Europe | Acupuncture, treatment of physician choice, according to the standard of care | IRCCS Azienda Ospedaliero-Universitaria di Bologna, Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Peripheral Neuropathy | 12/23 | 12/23 | | |
NCT04770376: Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 and Endothelial Internal Tunica Cell Kinase 2 in Patients With Ovarian Cancer Treated With Chemotherapy Associated to Bevacizumab |
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| Recruiting | N/A | 150 | Europe | Observational study. Blood samples will be collected at scheduled blood draws performed as per clinical practice before each cycle of chemotherapy. | IRCCS Azienda Ospedaliero-Universitaria di Bologna, Ospedale SS Giovanni e Paolo, Venezia | Ovarian Cancer | 12/23 | 12/23 | | |
NCT06800612: Evaluating Efficacy and Tolerability of Anticancer Drug Therapies for the Treatment of Gynecologic and Breast Cancers |
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| Recruiting | N/A | 100 | Europe | Oncologic drugs administered for treatment of breast cancer, Oncologic drug administered for treatment of gynecologic cancer | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic, Ovarian Cancer, Cervical Carcinoma, Endometrial Cancer | 12/30 | 12/30 | | |
NCT02261389: Follow-up of Early Breast Cancer by Dynamic Evaluation of CEA and CA 15.3 Followed by 18FDG-PET |
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| Active, not recruiting | N/A | 1507 | Europe | Arm B, tumor markers assessment, CEA, CA15-3, 18FDG-PET | IRCCS Azienda Ospedaliero-Universitaria di Bologna, PONS-S (Patientenorientierte Nachsorge-Stiftung), Augsburg, Germany, Azienda ULSS 12 Veneziana, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | Breast Cancer | 11/26 | 12/30 | | |
| Caruso, Michele |
| Active, not recruiting | 3 | 368 | Europe, US, RoW | Abemaciclib, Fulvestrant, Placebo | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasm, Neoplasm Metastasis | 02/24 | 02/26 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
| Active, not recruiting | 2 | 256 | Europe, Canada, US, RoW | Avelumab, MSB0010718C, Sacituzumab Govitecan, IMMU-132, Trodelvyâ„¢, GS-0132, M6223, NKTR-255 | EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany; Gilead Sciences; Nektar Therapeutics | Locally Advanced or Metastatic Urothelial Carcinoma | 01/25 | 01/25 | | |
Key-Early, NCT06467383: A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced |
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| Recruiting | N/A | 600 | Europe | | MSD Italia S.r.l., YGHEA, CRO Division of Ecol Studio spa | Non-small Cell Lung Cancer, NSCLC, NSCLC, Stage III, NSCLC, Stage I | 06/25 | 06/25 | | |
| MIGDANIS, ATHANASIOS |
NCT05759689: Fat Supplementation on Dumping Syndrome Related Symptoms After Gastric Surgery |
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| Recruiting | N/A | 30 | Europe | Dietary Supplement: Resource Energy, Dietary Supplement: Calogen | Larissa University Hospital | Dumping Syndrome, Gastric Surgery | 09/24 | 09/24 | | |
| Arnaoutoglou, Eleni |
| Recruiting | N/A | 288 | Europe | Preoperative HbA1c | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, HbA1c | 09/21 | 11/21 | | |
| Recruiting | N/A | 288 | Europe | NLR, PLR | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio | 12/21 | 12/21 | | |
NCT04736303: The Impact of the Implementation of BIS on the Incidence of Postoperative Delirium |
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| Recruiting | N/A | 1400 | Europe | BIS | University of Thessaly | Postoperative Delirium | 12/22 | 04/23 | | |
NCT06614478: Frailty, Hip Fractures and Inflammatory Biomarkers |
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| Recruiting | N/A | 200 | Europe | | University of Thessaly | Frailty, Hip Fracture, Inflammatory Biomarkers | 12/25 | 01/26 | | |
NCT04380129: Music Therapy Model "The Bonny Method of Guided Imagery and Music" on Patients with Rheumatoid Arthritis |
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| Recruiting | N/A | 74 | Europe | Music therapy-conversation sessions, GIM Bonny Method, Music Listening | University of Thessaly | Rheumatoid Arthritis, Quality of Life, Chronic Pain | 01/25 | 02/25 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine, Remifentanil | University of Thessaly | Functional Endoscopic Sinus Surgery | 10/23 | 12/23 | | |
G-GFI, NCT05091645: Translation and Cultural Adaptation of the Groningen Frailty Indicator (GFI) in Patients With Hip Fracture |
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| Recruiting | N/A | 89 | Europe | GFI | University of Thessaly | Frailty Syndrome, Hip Fractures | 06/24 | 07/24 | | |
| Completed | N/A | 55 | Europe | VIOSync-SPI | Aisthesis Medical P.C., Larissa University Hospital, Technical University of Crete | Sepsis, Abdominal Sepsis, Infections, Clinical Deterioration, Hemodynamic Instability | 06/24 | 06/24 | | |
| Not yet recruiting | N/A | 200 | Europe | Dexmedetomidine | University of Thessaly | Acute Kidney Injury, Dexmedetomidine, Endovascular Aortic Repair | 11/23 | 02/24 | | |
| Recruiting | N/A | 30 | Europe | ERAS | University of Thessaly | ERAS, Craniotomy | 05/24 | 07/24 | | |
CoFA-TAAA, NCT06432387: Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair |
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| Not yet recruiting | N/A | 58 | Europe | Patients undergoing complex thoraco-abdominal aortic aneurysm repair | University of Thessaly | Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation | 12/25 | 01/26 | | |
| Recruiting | N/A | 64 | Europe | | University of Thessaly | Venous Thromboembolism, Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma | 09/24 | 10/24 | | |
NCT04108546: Massage and Electroacupuncture in Chronic Lumbar Pain |
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| Recruiting | N/A | 110 | Europe | Electroacupuncture device, Epidural analgesia | University of Thessaly | Back Pain, Lumbar, Anesthesia, Local, Epidural, Electroacupuncture, Massage | 10/24 | 12/24 | | |
NCT05518643: Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes |
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| Recruiting | N/A | 120 | Europe | ERAS protocol | University of Thessaly, IASO Thessalias, Larissa University Hospital | ERAS, Pancreas Cancer, Pancreas; Fistula, Delayed Gastric Emptying, Surgery-Complications, Pancreatic Hemorrhage, PROMs | 08/25 | 08/26 | | |
| Tepetes, Konstantinos |
NCT04949646: Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision |
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| Recruiting | N/A | 44 | Europe | Pelvic Intraoperative Neuromonitoring | Larissa University Hospital, General Hospital of Larissa, University of Thessaly | Rectal Neoplasms | 09/26 | 09/27 | | |
| Perivoliotis, Konstantinos |
NCT04949646: Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision |
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| Recruiting | N/A | 44 | Europe | Pelvic Intraoperative Neuromonitoring | Larissa University Hospital, General Hospital of Larissa, University of Thessaly | Rectal Neoplasms | 09/26 | 09/27 | | |
NCT05496491: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial |
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| Recruiting | N/A | 84 | Europe | Neoadjuvant Chemoradiotherapy, nCRT, Adjuvant Chemotherapy, AC, Consolidation Chemotherapy, CC | Larissa University Hospital | Rectal Neoplasms | 08/26 | 08/26 | | |
NCT05713903: Laparoscopic Versus Open Right Colectomy for Right Colon Cancer |
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| Recruiting | N/A | 114 | Europe | Laparoscopic right colectomy, Open right colectomy | Larissa University Hospital | Colon Cancer | 01/26 | 01/27 | | |
| Giannoukas, Athanasious |
| Active, not recruiting | N/A | 3638 | Europe, Canada, Japan, US, RoW | CEA, CAS | University of Oxford, NHS Health Technology Assessment Programme, BUPA Foundation, British Heart Foundation | Carotid Stenosis | 12/20 | 12/25 | | |
| Sultan, Sherif |
NCT05495750: Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries |
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| Completed | 4 | 30 | RoW | Bupivacaine 0.25% Injectable Solution, supra zygomatic maxillary nerve block | Alaa Mohamed Abdel Salam Ibrahim Soliman | Perioperative Inflammatory Response, Postoperative Pain | 01/24 | 02/24 | | |
NCT03929354: Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis |
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| Recruiting | N/A | 208 | Europe | Risk Factors Modification Programme, Standard Care | Western Vascular Institute, Ireland | Carotid Stenosis | 09/22 | 09/22 | | |
NCT03935776: Lifestyle Modification Programme for Patients With Peripheral Arterial Disease |
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| Recruiting | N/A | 208 | Europe | Risk Factors Modification Programme, Standard Healthcare | Western Vascular Institute, Ireland | Peripheral Arterial Occlusive Disease | 09/22 | 09/22 | | |
| Recruiting | N/A | 150 | Europe, RoW | Endurant Chimney Graft Technique | Medtronic Cardiovascular | AAA - Abdominal Aortic Aneurysm | 03/26 | 07/30 | | |
| Matsagkas, Miltiadis |
| Recruiting | N/A | 150 | Europe, RoW | Endurant Chimney Graft Technique | Medtronic Cardiovascular | AAA - Abdominal Aortic Aneurysm | 03/26 | 07/30 | | |
| Papazoglou, Kostantinos |
| Recruiting | N/A | 157 | Europe | Endovascular repair of ruptured abdominal aortic aneurysm (EVAR) with Medtronic Endurant | Kostantinos Papazoglou, Medtronic, Aristotle University Of Thessaloniki | Rupture, Aortic, Aneurysm, Abdominal Aortic, Aneurysm, Ruptured | 02/22 | 02/23 | | |
| Recruiting | N/A | 150 | Europe, RoW | Endurant Chimney Graft Technique | Medtronic Cardiovascular | AAA - Abdominal Aortic Aneurysm | 03/26 | 07/30 | | |
| Intrieri, Francesco |
| Recruiting | N/A | 150 | Europe, RoW | Endurant Chimney Graft Technique | Medtronic Cardiovascular | AAA - Abdominal Aortic Aneurysm | 03/26 | 07/30 | | |
| Zagouri, Flora |
NCT05874401: Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan |
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| Recruiting | 4 | 302 | Europe, RoW | Trilaciclib, G1T28, CDK 4/6 inhibitor, cyclin-dependent kinase 4/6 inhibitor, Placebo, Topotecan, Hycamtin | G1 Therapeutics, Inc. | Extensive-stage Small-cell Lung Cancer | 07/27 | 07/27 | | |
| Active, not recruiting | 3 | 291 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Cabozantinib, Vandetanib | Loxo Oncology, Inc., Eli Lilly and Company | Medullary Thyroid Cancer | 05/23 | 02/26 | | |
| Active, not recruiting | 3 | 368 | Europe, US, RoW | Abemaciclib, Fulvestrant, Placebo | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasm, Neoplasm Metastasis | 02/24 | 02/26 | | |
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer |
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| Active, not recruiting | 3 | 866 | Europe, Japan, US, RoW | Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219 | Eli Lilly and Company, Eli Lilly and Company | Breast Neoplasms, Neoplasm Metastasis | 06/24 | 08/27 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
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| Active, not recruiting | 3 | 511 | Europe, US, RoW | HLX10, Serplulimab, carboplatin/cisplatin-etoposide, Thoracic radiotherapy, Placebo, Prophylactic Cranial Irradiation (PCI) | Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc. | Limited-Stage Small Cell Lung Cancer | 07/25 | 12/26 | | |
| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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| Recruiting | 3 | 560 | Europe, Canada, Japan, US, RoW | sigvotatug vedotin, SGN-B6A; PF-08046047, docetaxel | Seagen Inc. | Carcinoma, Non-Small-Cell Lung | 07/26 | 07/28 | | |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
AZUR-2, NCT05855200: Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer |
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| Recruiting | 3 | 711 | Europe, Canada, Japan, US, RoW | Dostarlimab, CAPEOX, FOLFOX | GlaxoSmithKline | Colonic Neoplasms, Neoplasms, Colon | 12/28 | 12/30 | | |
| Recruiting | 2 | 340 | Europe, Japan, US, RoW | Pembrolizumab, Dostarlimab, GSK4057190, Belrestotug, EOS884448, GSK4428859A, Nelistotug, GSK6097608 | GlaxoSmithKline, iTeos Therapeutics | Lung Cancer, Non-Small Cell | 10/25 | 10/28 | | |
| Active, not recruiting | 2 | 256 | Europe, Canada, US, RoW | Avelumab, MSB0010718C, Sacituzumab Govitecan, IMMU-132, Trodelvyâ„¢, GS-0132, M6223, NKTR-255 | EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany; Gilead Sciences; Nektar Therapeutics | Locally Advanced or Metastatic Urothelial Carcinoma | 01/25 | 01/25 | | |
| Pantazopoulos, Ioannis |
NCT05729204: Washing COVID-19 Away With a Hypertonic Seawater Nasal Irrigation Solution |
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| Completed | N/A | 56 | Europe | Hypertonic seawater solution, Sinomarin | Larissa University Hospital | SARS-CoV2 Infection | 11/22 | 12/22 | | |
NCT05755425: CPAP Versus HFNO for the Treatment of Acute Hypoxemic Respiratory Failure Due to Community Acquired Pneumonia |
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| Recruiting | N/A | 100 | Europe | CPAP, HFNO | Evangelismos Hospital, University of Thessaly | Pneumonia, Respiratory Failure | 12/23 | 01/24 | | |
NCT05829083: DUET Versus Standard Interface for Hypercapnic COPD Patients |
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| Recruiting | N/A | 50 | Europe | Asymmetric nasal cannula - DUET, Conventional nasal high flow cannula | Larissa University Hospital, Sotiria General Hospital | COPD Exacerbation, Hypercapnia, COPD | 04/24 | 05/24 | | |
| Ntalouka, Maria |
| Recruiting | N/A | 288 | Europe | Preoperative HbA1c | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, HbA1c | 09/21 | 11/21 | | |
| Recruiting | N/A | 288 | Europe | NLR, PLR | University of Thessaly, University Hospital, Ioannina, Larissa University Hospital | Neurocognitive Disorders, Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio | 12/21 | 12/21 | | |
