| Borlaug, Barry |
NCT05983250: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF |
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| Recruiting | 3 | 152 | Canada, US | TNX-103, Placebo | Tenax Therapeutics, Inc., Medpace, Inc., Northwestern University | Pulmonary Hypertension | 03/27 | 07/27 | | |
NCT05371496: Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction |
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| Recruiting | 2 | 81 | US | Semaglutide, Placebo, Counselling on healthy lifestyle intervention | Mayo Clinic, United States Department of Defense | Cardiomyopathy, Heart Failure With Preserved Ejection Fraction (HFpEF), Obesity | 08/26 | 08/26 | | |
| Recruiting | N/A | 80 | US | Satera GSN Ablation, Sham Control | Axon Therapies, Inc. | Heart Failure With Preserved Ejection Fraction | 04/22 | 03/23 | | |
| Recruiting | N/A | 1500 | Europe, US, RoW | assessment of pulmonary hemodynamics during exercise by right heart catheterization | Medical University of Graz, European Respiratory Society | Pulmonary Circulation Diseases | 12/29 | 12/29 | | |
| Recruiting | N/A | 750 | Europe, Canada, US, RoW | Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE) | Corvia Medical | Heart Failure, Heart Failure, Diastolic | 05/25 | 03/31 | | |
NCT06195059: Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume |
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| Recruiting | N/A | 800 | US | | Mayo Clinic | Heart Failure, Pulmonary Vascular Disease | 11/26 | 11/26 | | |
NCT06517186: Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction |
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| Recruiting | N/A | 180 | US | | Northwestern University, National Heart, Lung, and Blood Institute (NHLBI), Massachusetts General Hospital, Brigham and Women's Hospital, Mayo Clinic, Wake Forest University Health Sciences, University of Pennsylvania | Heart Failure, Heart Failure With Preserved Ejection Fraction | 06/26 | 06/26 | | |
| Not yet recruiting | N/A | 10 | NA | PeriCut Catheter System performs minimally invasive pericardiotomy | Heart Failure Solutions, Inc., Mayo Clinic | Heart Failure With Preserved Ejection Fraction | 05/26 | 05/26 | | |
| Recruiting | N/A | 80 | US | Right Heart Catheterization with Hemodynamics and Limited Echocardiogram, Magnetic Resonance Imaging (MRI), CMR Imaging, Dual X-ray absorptiometry (DEXA) scan | Mayo Clinic | Healthy | 01/29 | 01/29 | | |
NCT05873634: HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets |
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| Recruiting | N/A | 1000 | US | | Northwestern University, National Heart, Lung, and Blood Institute (NHLBI), Massachusetts General Hospital, Brigham and Women's Hospital, Mayo Clinic, University of California, Davis, Wake Forest University Health Sciences, University of Pennsylvania | Heart Failure, Heart Failure With Preserved Ejection Fraction | 06/26 | 06/26 | | |
| Recruiting | N/A | 3000 | US | Transthoracic Echocardiography (TTE), Lung ultrasound | Mayo Clinic, National Heart, Lung, and Blood Institute (NHLBI) | Pulmonary Hypertension, Pulmonary Vascular Disease, Left Heart Disease | 05/28 | 05/28 | | |
| Castillo, Manuel J |
| Recruiting | N/A | 200 | Europe, Canada, US | AVP III | Abbott Medical Devices | Paravalvular Aortic Regurgitation | 07/25 | 06/26 | | |
| Recruiting | N/A | 750 | Europe, Canada, US, RoW | Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE) | Corvia Medical | Heart Failure, Heart Failure, Diastolic | 05/25 | 03/31 | | |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
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| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
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| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR |
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| Recruiting | N/A | 300 | Europe, US | Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication | Cardiac Dimensions, Inc. | Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases | 12/26 | 12/30 | | |
