| Cheng, Xiangdong |
NCT03973008: Adujvant CT+CRT vs Adujvant CT After D2 Resection for Locally Advanced Proximal Gastric Adenocarcinoma |
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| Recruiting | 3 | 408 | RoW | Adjuvant Chemoradiotherapy, CRT, Adjuvant Chemotherapy, CT | Zhejiang Cancer Hospital | Gastric Adenocarcinoma | 02/24 | 05/25 | | |
NCT04135781: Nab-paclitaxel Combined With S-1 as Adjuvant Chemotherapy for Stage Ⅲ Gastric Cancer |
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| Recruiting | 3 | 616 | RoW | nab paclitaxel, albumin bound paclitaxel, Tegafur, S-1, Oxaliplatin, Capecitabine | Zhejiang Cancer Hospital, CSPC Ouyi Pharmaceutical Co., Ltd. | Stomach Cancer | 10/24 | 10/24 | | |
| Active, not recruiting | 2/3 | 580 | RoW | Apatinib 250mg, Camrelizumab, S-1, Oxaliplatin, Apatinib 500mg | Ruijin Hospital | Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma | 12/24 | 08/25 | | |
NCT05009953: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer |
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| Terminated | 2 | 17 | RoW | Irinotecan Liposome Injection, SG001, Fluorouracil, Leucovorin | CSPC Ouyi Pharmaceutical Co., Ltd. | Advanced Biliary Tract Cancer, Intrahepatic Cholangiocarcinoma, Extrahepatic Cholangiocarcinoma, Gallbladder Carcinoma | 01/23 | 01/23 | | |
| Not yet recruiting | 2 | 134 | RoW | Tislelizumab, SOX/XELOX | Xiangdong Cheng, Liaoning Tumor Hospital & Institute, Shanxi Province Cancer Hospital, Sichuan Cancer Hospital and Research Institute, The Second Affiliated Hospital of Harbin Medical University | Gastric Cancer | 03/26 | 03/28 | | |
| Not yet recruiting | 2 | 50 | RoW | Liposomal Irinotecan Hydrochloride | Zhejiang Cancer Hospital | Gastric Cancer | 02/25 | 02/26 | | |
NCT05864105: PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma |
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| Recruiting | 2 | 35 | RoW | PM8002, FOLFOX regimen | Biotheus Inc. | Hepatocellular Carcinoma | 06/26 | 06/26 | | |
NCT06586294: A Study of Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma |
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| Not yet recruiting | 1/2 | 294 | RoW | Drug: AK129 Drug：oxaliplatin Drug：capecitabine, Drug: AK129 Drug：cadonilimab Drug：oxaliplatin Drug：capecitabine | Akeso | Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | 07/26 | 07/26 | | |
| Not yet recruiting | 1/2 | 54 | RoW | QL1706 combined with SOX | Xiangdong Cheng | Gastric Cancers, Esophagogastric Junction Cancers | 02/26 | 06/31 | | |
NCT05972460: IMM2510, a PD-L1 and VEGF Bispecific Fusion Protein, in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 108 | RoW | IMM2510, IMM2510 Injection | ImmuneOnco Biopharmaceuticals (Shanghai) Inc., Zhejiang Cancer Hospital, Fudan University | Advanced Solid Tumors | 12/23 | 10/24 | | |
NCT05911984: A Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties and Preliminary Efficacy of 9MW3811 in Patients With Advanced Solid Tumors |
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| Not yet recruiting | 1 | 27 | RoW | 9MW3811 Injection | Mabwell (Shanghai) Bioscience Co., Ltd. | Advanced Malignant Solid Tumor | 03/24 | 03/24 | | |
NCT05441046: Genakumab Alone and in Combination With Tislelizumab in Patients With Advanced Malignant Solid Tumors |
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| Recruiting | 1 | 120 | RoW | Genakumab, Tislelizumab | GeneScience Pharmaceuticals Co., Ltd. | Malignant Solid Tumors | 06/24 | 03/25 | | |
NCT06610799: Study of IBI363 in Patients With Advanced First-line Gastric Cancer |
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| Not yet recruiting | 1 | 40 | RoW | IBI363 | Xiangdong Cheng | IBI363 + Chemotherapy | 06/25 | 12/26 | | |
BAT-8007-001-CR, NCT05879627: To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 250 | RoW | BAT8007 for injection, Recombinant all human anti Nectin-4 monoclonal antibody for injection Exatecan conjugate | Bio-Thera Solutions, Zhejiang Tumor Hospital | Advanced Solid Tumors | 12/24 | 07/25 | | |
NCT05048134: A Phase I Study of HRS2300 or Combined With SHR-1316 or SHR-1701 or Trametinib or Almonertinib in Patients With Advanced Malignancies |
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| Terminated | 1 | 13 | RoW | HRS2300, HRS2300、 SHR-1316, HRS2300、SHR-1701, HRS2300、trametinib, HRS2300、Almonertinib | Jiangsu HengRui Medicine Co., Ltd. | Advanced Malignancies | 02/23 | 05/23 | | |
| Recruiting | 1 | 71 | RoW | TQB2103 for injection | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Advanced Malignant Neoplasm | 05/25 | 05/25 | | |
NCT05836948: The Clinical Study of SHR-9839 for Injection in Patients With Advanced Solid Tumors |
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| Not yet recruiting | 1 | 174 | RoW | SHR-9839 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Advanced Solid Tumor | 05/26 | 06/26 | | |
NCT04657848: Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal Gastrectomy |
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| Recruiting | N/A | 100 | RoW | proximal gastrectomy combined with Cheng's Giraffe reconstruction | Zhejiang Cancer Hospital | Gastric Cancer, Reflux Esophagitis | 06/21 | 06/23 | | |
NCT04793672: Establishment of Tongue Image Database and Machine Learning Model for Malignant Tumors Diagnosis |
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| Completed | N/A | 4100 | RoW | Tongue images, coating on the tongue and clinical data of patients with malignant tumors and healthy people will be collected. | Zhejiang Cancer Hospital, Sichuan Cancer Hospital and Research Institute, Zhejiang Hospital of TCM, Wenzhou Medical University, Fujian Cancer Hospital, RenJi Hospital, Tongde Hospital of Zhejiang, Kecheng District People's Hospital, Yueyang Central Hospital, Shandong Cancer Hospital and Institute, Shanxi Province Cancer Hospital, Liaoning Tumor Hospital & Institute, Harbin Cancer Hospital, Yuhang District People's Hospital, Hainan Cancer Hospital, Zigong Fourth People's Hospital, Henan University of Science and Technology | Malignant Tumor | 04/22 | 12/23 | | |
NCT05385809: A Retrospective Study of Immunotherapy in Conversion Therapy of Unresectable Gastric Cancer |
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| Recruiting | N/A | 100 | RoW | | Zhejiang Cancer Hospital, Innovent Biologics, Inc. | Unresectable Gastric Cancer | 07/22 | 12/23 | | |
NCT05269056: Early Detection of Gastric Cancer Using Plasma Cell-free DNA Fragmentomics |
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| Recruiting | N/A | 300 | RoW | | Zhejiang Cancer Hospital, Nanjing Geneseeq Technology Inc | Early Gastric Cancer | 11/22 | 05/23 | | |
| Recruiting | N/A | 200000 | RoW | questionnaire, Helicobacter pylori (H. pylori) test, fecal immunochemical test (FIT) | Zhejiang Cancer Hospital, Fenghua District People's Hospital, Ningbo City, Fenghua District Traditional Chinese Medicine Hospital, Ningbo City, Xikou Hospital in Fenghua District, Ningbo City, Yongkang Traditional Chinese Medicine Hospital, Yongkang First People's Hospital | Gastrointestinal Tumors | 12/27 | 12/28 | | |
NCT06642857: Multi-omics Based Prediction of Treatment Response to Immunotherapy Combined with Chemotherapy in Advanced Gastric/Gastroesophageal Junction Cancer. |
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| Recruiting | N/A | 150 | RoW | Peripheral blood, tougue coating, saliva, and feces | Xiangdong Cheng | Advanced Gastric Carcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 02/26 | 02/26 | | |
NCT05794841: Multi-omics Study of Tongue Coating in Malignant Tumors of Digestive Tract |
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| Recruiting | N/A | 20000 | RoW | Tongue coating sample collection and multi-omics analysis | Zhejiang Cancer Hospital, First Affiliated Hospital of Wenzhou Medical University, Liaoning Tumor Hospital & Institute, RenJi Hospital, Fujian Cancer Hospital, Sun Yat-sen University, The Second Affiliated Hospital of Harbin Medical University, Sichuan Cancer Hospital and Research Institute, Zhejiang Provincial Tongde Hospital, Yuhang District Hospital of Traditional Chinese Medicine, The First People's Hospital of Yuhang District, The First Affiliated Hospital of Anhui University of Chinese Medicine, BGI-Shenzhen, Shangyu People's Hospital, Xianju People's Hospital, Shanghai Zhongshan Hospital | Malignant Tumors of Digestive Tract | 03/24 | 03/25 | | |
NCT06614179: A Pan-cancer Screening and Diagnosis Model Based on Abdominal CT Was Established |
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| Recruiting | N/A | 100000 | RoW | | Xiangdong Cheng | Abdominal Neoplasm | 12/29 | 12/29 | | |
NCT05991947: Preliminary Experimental Study on Key Technologies for Early Screening of Gastric Cancer |
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| Recruiting | N/A | 1100 | NA | No intervention | Zhejiang Cancer Hospital | Gastric Cancer, Healthy | 12/25 | 12/25 | | |
NCT05617469: DLCS for Predicting Neoadjuvant Chemotherapy Response |
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| Recruiting | N/A | 1100 | RoW | develop and visualized a radio-clinical signatures from pretreatment oversampled CT images | Zhejiang Cancer Hospital | Gastric Cancer, CT Images, Deep Learning, Neoadjuvant Chemotherapy, Tumor Regression Grade | 01/23 | 07/23 | | |
| Chen, Qixun |
NCT04316364: A Trial of SHR-1316/Placebo in Combination With Chemotherapy in Patients With Resectable NSCLC |
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| Recruiting | 3 | 537 | RoW | SHR-1316、Paclitaxel (Albumin Bound)、Carboplatin, SHR-1316、Chemotherapeutic, Placebo、Chemotherapeutic | Jiangsu HengRui Medicine Co., Ltd. | Non-Small-Cell Lung Cancer | 04/23 | 12/26 | | |
POINT, NCT04513418: Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy |
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| Recruiting | 3 | 244 | RoW | Preoperative immunonutrition | Hecheng Li M.D., Ph.D, Shanghai Chest Hospital, Shanghai Zhongshan Hospital, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University, Ningbo Medical Center Lihuili Hospital, Zhejiang Cancer Hospital, Fujian Medical University Union Hospital, Shanghai East Hospital | Esophageal Neoplasms | 03/25 | 12/28 | | |
NCT04848753: Perioperative Toripalimab (JS001) Combined With Neoadjuvant Chemotherapy in Patients With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma |
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| Active, not recruiting | 3 | 663 | RoW | Toripalimab combined with cisplatin and paclitaxel, Placebo combined with cisplatin and paclitaxel | Shanghai Junshi Bioscience Co., Ltd. | Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma | 05/27 | 05/27 | | |
| Recruiting | 3 | 170 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Placebo | Loxo Oncology, Inc., Eli Lilly and Company | Carcinoma, Non-Small-Cell Lung | 05/27 | 08/32 | | |
WATCHER, NCT05507411: Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC |
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| Recruiting | 2 | 100 | RoW | Neoadjuvant Radiotherapy, Neoadjuvant Chemotherapy, Immunotherapy | Zhejiang Cancer Hospital, Jiangsu HengRui Medicine Co., Ltd. | Esophageal Squamous Cell Carcinoma | 04/24 | 04/27 | | |
NCT06443684: A Study of Molecular Residual, Dynamic Monitoring and Recurrence of Stage III Driver Mutated NSCLC |
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| Recruiting | N/A | 305 | RoW | MRD | Shanghai Chest Hospital | Non Small Cell Lung Cancer | 03/25 | 03/26 | | |
NCT04830826: A Real-world Study of Adjuvant Therapy in Early Stage NSCLC With EGFR Mutation-Positive in China |
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| Recruiting | N/A | 2000 | RoW | Surgeries | The First Affiliated Hospital of Guangzhou Medical University | NSCLC, Stage I, NSCLC, Stage II, NSCLC, Stage III | 01/24 | 07/24 | | |
| Wang, Xinbao |
| Recruiting | N/A | 10000 | RoW | | Shanghai Jiao Tong University School of Medicine, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, First Affiliated Hospital Bengbu Medical College, LanZhou University, Henan Cancer Hospital, The First Affiliated Hospital of Zhengzhou University, The Second Affiliated Hospital of Harbin Medical University, First Affiliated Hospital of Harbin Medical University, Harbin Medical University, The First Hospital of Jilin University, Second Hospital of Jilin University, China-Japan Union Hospital, Jilin University, The First People's Hospital of Changzhou, Changzhou No.2 People's Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, The First People's Hospital of Taicang, Wuxi Second People's Hospital, Xuzhou Central Hospital, Second Affiliated Hospital of Suzhou University, Affiliated Hospital of Nantong University, The First People's Hospital of Nantong, The Affiliated Hospital of Xuzhou Medical University, Second Affiliated Hospital of Nanchang University, The First Affiliated Hospital of Nanchang University, Jiangxi Provincial People's Hopital, Shengjing Hospital, Baotou Central Hospital, Qinghai People's Hospital, Changzhi Medical College, The First Affiliated Hospital of Shanxi Medical University, Shanxi Provincial Cancer Hospital, First Affiliated Hospital Xi'an Jiaotong University, Eastern Hepatobiliary Surgery Hospital, Shanghai Fengxian District Central Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Zhongshan Hospital, Shanghai Pudong Hospital, Central Hospital of Minhang District, Shanghai, Putuo District People's Hospital of Shanghai, Xinhua (Chongming) Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Tianjin Medical University Cancer Hospital, First Affiliated Hospital of Xinjiang Medical University, The First Affiliated Hospital of Kunming Medical College, Yinzhou Hospital Affiliated to Medical School of Ningbo University, Shaoxing Second Hospital, Shaoxing People's Hospital, First Affiliated Hospital of Wenzhou Medical University, Sir Run Run Shaw Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Cancer Hospital, Huizhou Municipal Central Hospital, Ningbo No. 1 Hospital, People's Hospital of Hunan Province, Hainan People's Hospital, Taizhou Municipal Hospital, Xinghua City People's Hospital, Tongliao City Hospital, Jiangxi Provincial Cancer Hospital, Shandong Provincial Hospital, Qilu Hospital of Shandong University, The Affiliated Hospital of Qingdao University, Xijing Hospital | Gallbladder Neoplasms | 12/22 | 12/25 | | |
NCT04078230: Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma |
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| Recruiting | N/A | 168 | US, RoW | Extend LymphAdenectomy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intrahepatic Cholangiocarcinoma | 12/27 | 12/27 | | |
| Fang, Jun |
NCT06319456: A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. |
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| Recruiting | 3 | 344 | RoW | Lisaftoclax (APG-2575), Acalabrutinib, Fludarabine, Cyclophosphamide，CTX, Rituximab, Chlorambucil | Ascentage Pharma Group Inc. | CLL/SLL | 08/27 | 08/28 | | |
NCT05466279: The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients |
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| Completed | N/A | 131 | RoW | remazolam, Propofol, Midazolam | Fang Jun | Postoperative Delirium | 10/23 | 10/23 | | |
NCT06658080: Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer |
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| Recruiting | N/A | 90 | RoW | organoid drug test | Second Affiliated Hospital, School of Medicine, Zhejiang University | Breast Cancer Metastatic, Hydrothorax, Ascites, Organoids, Drug Evaluation | 10/26 | 10/27 | | |
| Hu, Hai |
FGCL-4592-898, NCT05301517: A Study to Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia in Participants Receiving Chemotherapy Treatment for Non-Myeloid Malignancies |
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| Completed | 3 | 159 | RoW | SEPO®, Recombinant human erythropoietin-α [rHuEPO-α], Roxadustat, FG-4592 | FibroGen | Chemotherapy Induced Anemia | 04/23 | 04/23 | | |
NCT06419621: PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic Triple-negative Breast Cancer |
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| Recruiting | 3 | 360 | RoW | PM8002, Nab-Paclitaxel, Placebo | Biotheus Inc. | Triple Negative Breast Cancer(TNBC) | 07/27 | 07/28 | | |
JSKN003-302, NCT06079983: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects |
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| Not yet recruiting | 3 | 400 | RoW | JSKN003, Capecitabine tablets, Gemcitabine hydrochloride for injection, Vinorelbine tartrate injection, Paclitaxel for injection (albumin-bound type), Docetaxel injection, Eribulin mesylate injection | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Breast Cancer | 04/25 | 03/29 | | |
NCT06001528: Serum and Tissue Metabolite-based Prediction of Sentinel Lymph Node Metastasis in Breast Cancer |
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| Recruiting | N/A | 2400 | RoW | | Shantou Central Hospital, Zhejiang Cancer Hospital, Sichuan Cancer Hospital and Research Institute, Shenshan Medical Center of Sun Yat-sen Memorial Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Breast Cancer, Lymph Node Metastasis | 12/23 | 08/26 | | |
NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients |
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| Recruiting | N/A | 570 | RoW | Stent-based Diverting Technique | Sir Run Run Shaw Hospital | Rectal Neoplasms | 12/24 | 06/25 | | |
NCT06717854: Retrograde and Antegrade Enema for Prevention of LARS After LAR: a Randomized Controlled Trial |
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| Not yet recruiting | N/A | 72 | RoW | transanal irrigation, antegrade enema | Sichuan Cancer Hospital and Research Institute | Low Anterior Resection Syndrome | 12/26 | 12/26 | | |
| xie, Kangjie |
NCT06426953: Predictive Effect of TGF-β and INS-PI3K-AKT Related Proteins for POD in Diabetes Patients |
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| Recruiting | N/A | 180 | RoW | No intervention | Xie Kangjie | Diabetes, Postoperative Delirium | 06/25 | 06/26 | | |
