| Chen, Jean |
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk |
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| Active, not recruiting | 3 | 2749 | Europe, US, RoW | Orforglipron, LY3502970, Insulin Glargine | Eli Lilly and Company | Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease | 09/25 | 01/26 | | |
| Active, not recruiting | 3 | 15374 | Europe, Canada, Japan, US, RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Obesity, Overweight | 10/27 | 10/27 | | |
OPTI-2, NCT06238778: Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec |
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| Recruiting | 2 | 230 | US | HDV-Lispro, HDV-L, Lispro, LIS | Diasome Pharmaceuticlas, Inc. | Diabetes Mellitus, Type 1 | 06/25 | 12/25 | | |
ZONE, NCT05762107: A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes |
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| Recruiting | 2 | 186 | Canada, US | Placebo, ZT-01, 7 mg, ZT-01, 15 mg, ZT-01, 22 mg | Zucara Therapeutics Inc. | Type 1 Diabetes Mellitus with Hypoglycemia | 06/25 | 07/25 | | |
NCT06273124: Investigational Extended Wear Insulin Infusion Set in People With Type 1 Diabetes |
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| Completed | N/A | 260 | US | SteadiSet Extended Wear Infusion Set | Tandem Diabetes Care, Inc., Jaeb Center for Health Research | Type1diabetes | 12/24 | 12/24 | | |
NCT06719531: SYNERGY PLUS: Evaluation of Next Generation Sensors (NGS) and Algorithm in Patients with Type 1 and Type 2 Diabetes |
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| Not yet recruiting | N/A | 1500 | US | Continuous Glucose Monitoring | Medtronic Diabetes | Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus | 12/25 | 12/25 | | |
| Recruiting | N/A | 925 | US | Blood glucose meter, Eversense CGM System | Senseonics, Inc. | Diabetes | 03/26 | 03/26 | | |
| Malik, Arshad Nawaz AN |
OPTI-2, NCT06238778: Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec |
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| Recruiting | 2 | 230 | US | HDV-Lispro, HDV-L, Lispro, LIS | Diasome Pharmaceuticlas, Inc. | Diabetes Mellitus, Type 1 | 06/25 | 12/25 | | |
NCT05769608: A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects with Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen |
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| Active, not recruiting | 2 | 285 | US | Placebo, lorundrostat Dose 1, lorundrostat Dose 2 | Mineralys Therapeutics Inc. | Hypertension | 01/25 | 02/25 | | |
NCT05026099: Boxing Training for Upper Limb Functions, Balance, and Quality of Life in Stroke |
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| Completed | N/A | 30 | RoW | Boxing training, Task Oriented Training | Riphah International University | Stroke | 08/22 | 08/22 | | |
| Completed | N/A | 30 | RoW | Simultaneous Cervical Traction & Neural Mobilization, consecutive Cervical Traction & Neural Mobilization | Riphah International University | Cervical Radiculopathy | 08/22 | 08/22 | | |
| Completed | N/A | 40 | RoW | Exergaming low intensity group, Exergaming moderate intensity group, Exergaming high intensity group, control group exergaming | Riphah International University | Mild Cognitive Impairment | 08/22 | 08/22 | | |
NCT05129683: Single Session of Anodal Cerebellar vs Cerebral Transcranial Direct Current Stimulation in Stroke Patients |
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| Completed | N/A | 66 | RoW | Anodal tDCS cerebellar stimulation group, Anodal tDCS cerebral (M1) stimulation group, sham group | Riphah International University | Stroke | 09/22 | 09/22 | | |
NCT05338918: Effect of Mental Imagery on Lower Limb Functions in Stroke |
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| Completed | N/A | 28 | RoW | Mental Imagery with Virtual Reality Training, Virtual Reality Training | Riphah International University | Stroke | 02/23 | 02/23 | | |
NCT05771805: Additional Effects of Vagus Nerve Stimulation on Motor Functions of Upper-limb in Stroke |
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| Completed | N/A | 50 | RoW | Vagus nerve stimulation with task oriented training, Task oriented training | Riphah International University | Stroke (CVA) or TIA | 07/23 | 07/23 | | |
| Recruiting | N/A | 28 | RoW | Mental imagery technique, Virtual Reality technique | Riphah International University | Stroke | 09/23 | 09/23 | | |
NCT05449301: Effects of Unilateral Step Training on Gait and Balance in Stroke Patients |
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| Not yet recruiting | N/A | 63 | RoW | Rhythmic Auditory Stimulation, Treadmill Training, Unilateral Step Training | Riphah International University | Stroke | 12/23 | 12/23 | | |
NCT05158543: Intensity Dependent Effects of 'FAST-Table' on Physical Performance in Stroke |
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| Completed | N/A | 90 | RoW | conventional therapy, Task oriented training (moderate intensity), Task oriented training (high intensity) | Riphah International University | Stroke | 04/24 | 04/24 | | |
| Not yet recruiting | N/A | 210 | RoW | | Riphah International University | Heart Failure | 12/23 | 12/23 | | |
NCT06437704: Effects of Brain Training Games on Cognitive Function and Quality of Life in MCI |
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| Recruiting | N/A | 44 | RoW | Brain training game Lumosity, Simulation game simcity buildit | Riphah International University | Mild Cognitive Impairment | 10/24 | 10/24 | | |
NCT06757088: Combined Effects of Transcranial Direct Current Stimulation on Postural Control in Elderly |
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| Recruiting | N/A | 52 | RoW | M1 Stimulation Group, Cerebellar Stimulation Group (CbSG), M1 + Cerebellar Stimulation Group, Sham Stimulation Group | Riphah International University | Postural; Defect | 05/25 | 05/25 | | |
| Recruiting | N/A | 46 | RoW | Augmented Reality, Traditional Training | Riphah International University | Stroke/Brain Attack | 06/25 | 06/25 | | |
NCT06032780: Eccentric Resistance Training Among Individuals With Chronic Heart Failure |
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| Recruiting | N/A | 84 | RoW | Eccentric Resistive Training + Aerobic training Group, Resistance Training + Aerobic training Group, Aerobic training Group | Riphah International University | Heart Failure | 12/25 | 12/25 | | |
TRANSFORM, NCT06112418: A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events |
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| Recruiting | N/A | 7500 | US | The Cleerly CAD Staging System | Cleerly, Inc., CPC Clinical Research | Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome | 03/29 | 03/29 | | |
| Philipson, Lou |
OPTI-2, NCT06238778: Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec |
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| Recruiting | 2 | 230 | US | HDV-Lispro, HDV-L, Lispro, LIS | Diasome Pharmaceuticlas, Inc. | Diabetes Mellitus, Type 1 | 06/25 | 12/25 | | |
| Recruiting | N/A | 2000 | US | | University of South Florida, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases | 09/30 | 09/30 | | |
