| NSEIR, Saad |
| Recruiting | 4 | 154 | Europe | ceftriaxone, ciprofloxacin, imipenem, linezolid, placebo | University Hospital, Lille, Ministry of Health, France | Mechanical Ventilation Complication, Critical Illness | 09/23 | 09/23 | | |
Corticop, NCT04163536: Comparison of Corticosteroids vs Placebo on Duration of Ventilatory Support During Severe Acute Exacerbations of COPD Patients in the ICU |
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| Recruiting | 3 | 440 | Europe | Methylprednisolone, Placebos | Versailles Hospital | Chronic Obstructive Pulmonary Disease | 10/25 | 03/26 | | |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
| Recruiting | N/A | 1136 | Europe | | University Hospital, Lille | Severe COVID-19 | 12/22 | 12/22 | | |
| Recruiting | N/A | 194 | Europe | Biomarker strategy, Routine strategy | University Hospital, Lille | Invasive Candidiasis | 06/24 | 06/25 | | |
| Recruiting | N/A | 296 | Europe | | University Hospital, Lille | Invasive Fungal Disease, Critical Illness | 09/23 | 09/23 | | |
ATOMIC, NCT04530760: Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation |
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| Recruiting | N/A | 226 | Europe | | University Hospital, Lille | Critical Illness, Cirrhosis, Liver | 10/23 | 10/23 | | |
HyperBetashock, NCT04748796: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility |
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| Recruiting | N/A | 360 | Europe | echocardiography, Landiolol | Centre Hospitalier Universitaire, Amiens, CH Dieppe, CH Elbeuf, CH Le Havre, Centre Hospitalier de Beauvais, CH Compiègne, CH Laon, University Hospital, Caen, CH Cherbourg, University Hospital, Lille, CH Douai, CH Montreuil, Centre Hospitalier de Roubaix, Centre Hospitalier de Bethune, CH Lomme, Centre Hospitalier de Lens, Tourcoing Hospital, Centre Hospitalier VALENCIENNES, Centre Hospitalier Arras, Hospital Ambroise Paré Paris, University Hospital, Brest, Henri Mondor University Hospital, Hospital Avicenne, University Hospital, Montpellier, CH Calais, Hôpital Edouard Herriot, Centre Hospitalier Universitaire de Nīmes, Groupe Hospitalier Pitié-Salpêtrière | Septic Shock, Tachycardia, Mortality During Septic Shock, Beta-blocker | 02/24 | 03/24 | | |
VAPERO, NCT03711331: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia |
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| Recruiting | N/A | 160 | Europe | FilmArray® Pneumonia panel plus, Standard care | University Hospital, Lille, Curetis GmbH | Pneumonia, Ventilator-Associated, Pneumonia, Bacterial | 06/24 | 06/24 | | |
| Recruiting | N/A | 740 | Europe, Canada, US, RoW | Respiratory Mechanics, Standard Ventilation Strategy | Unity Health Toronto, Canadian Institutes of Health Research (CIHR), University of Toronto, Applied Health Research Centre | ARDS | 06/24 | 11/24 | | |
APAPI, NCT03763799: Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation |
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| Recruiting | N/A | 266 | Europe | PCR-based microbiological diagnosis strategy, Standard microbiological diagnosis strategy | University Hospital, Lille | Aspiration Pneumonia | 12/24 | 03/25 | | |
| Recruiting | N/A | 20000 | Europe, RoW | VAP | European Clinical Research Alliance for Infectious Diseases (ECRAID), Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL), Université de Genève (UNIGE), University Medical Center Utrecht (UMCU) | Ventilator Associated Pneumonia | 12/25 | 03/26 | | |
ASPIC, NCT05671328: Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia |
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| Not yet recruiting | N/A | 261 | NA | Biological examinations performed on blood and BAL | University Hospital, Lille, Pfizer | Ventilator Associated Pneumonia, Pulmonary Aspergillosis Invasive | 03/25 | 03/25 | | |
| Lakhal, Karim |
| Recruiting | 3 | 360 | Europe | Milrinone 1 Mg/mL Solution for Injection, Corotrope, Saline solution for injection, Sodium Chloride 0.9% | University Hospital, Angers | Vasospasm | 08/23 | 02/24 | | |
TREAT-HAP, NCT05914584: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. |
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| Not yet recruiting | 3 | 450 | Europe | Baricitinib 4 MG | Nantes University Hospital | Hospital-acquired Pneumonia | 08/25 | 12/25 | | |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
| Not yet recruiting | N/A | 5000 | Europe | questionnaire filling | Centre Hospitalier Universitaire de NÄ«mes | Critical Illness, Covid19, Stress Disorders, Post-Traumatic | 09/22 | 09/22 | | |
PREDIGAZ, NCT04538339: Prediction of Arterial Lactate and Blood Gas Values Through the Analysis of Central Venous Blood |
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| Completed | N/A | 398 | Europe | | Centre Hospitalier Régional d'Orléans | Circulatory Failure | 03/23 | 03/23 | | |
| Not yet recruiting | N/A | 640 | Europe | Patients of intensive care unit, Patients of surgical intensive care unit | Nantes University Hospital | Intensive Care Unit, Intraventricular Hemorrhage, External Ventricular Drain | 12/26 | 12/26 | | |
2PAC, NCT06032169: Ankle Measurements of Arterial Pressure: Semi-recumbent or Horizontal Position. |
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| Completed | N/A | 51 | Europe | Patients of a surgical intensive care unit having an arterial catheter | Nantes University Hospital | Intensive Care Unit, Arterial Catheter | 12/23 | 12/23 | | |
DETECT-AKI, NCT05283213: Development of an Innovative Clinico-biological Score for the Early Detection of Acute Renal Failure Associated With Cardiac Surgery. |
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| Recruiting | N/A | 400 | Europe | Early biomarkers of acute kidney injury | Nantes University Hospital, Roche Pharma AG, BiologBook, BioMérieux, ThermoFisher Scientific Brahms Biomarkers France | Acute Kidney Injury | 11/24 | 01/25 | | |
| HAYON, Jan |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
| LUYT, Charles Edouard |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
