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| Recruiting | 3 | 30 | Europe, US, RoW | Kedrion IVIG 10% | Kedrion S.p.A., Pharmaceutical company, KEDRION S.p.A, Kedrion S.p.A | Primary Immunodeficiency Disease | 04/26 | 10/26 | | |
NCT05677451: 24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up |
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| Recruiting | 3 | 100 | Europe, Canada, Japan, US, RoW | LOU064 (blinded), remibrutinib, placebo | Novartis Pharmaceuticals | Chronic Spontaneous Urticaria | 11/25 | 02/32 | | |
NCT05976243: A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines |
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| Recruiting | 3 | 348 | Europe, Canada, Japan, US, RoW | Remibrutinib, Placebo | Novartis Pharmaceuticals | Chronic Inducible Urticaria | 07/26 | 12/28 | | |
NCT05513001 / 2022-001034-11: An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib |
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| Active, not recruiting | 3 | 698 | Europe, Canada, Japan, US, RoW | LOU064 (blinded), remibrutinib, Placebo, LOU064 (open label) | Novartis Pharmaceuticals | Chronic Spontaneous Urticaria | 08/24 | 02/27 | | |
NCT04781387: Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection |
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| Active, not recruiting | 2 | 108 | Canada, US | CRS3123, Active Comparator | Crestone, Inc, National Institute of Allergy and Infectious Diseases (NIAID) | Clostridioides Difficile Infection | 02/24 | 04/24 | | |
CALM-CSU, NCT06077773: Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria |
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| Recruiting | 2 | 154 | Europe, Canada, US | Oral EP262, Placebo | Escient Pharmaceuticals, Inc | Chronic Spontaneous Urticaria | 06/25 | 07/25 | | |
NCT05347251: Effects of Cervicothoracic Mobility Program on Low Back Pain |
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| Completed | N/A | 44 | RoW | Cervicothoracic mobility program, Conventional Treatment | Riphah International University | Back Pain | 12/22 | 01/23 | | |
NCT05392023: Effects of Scapular Stabilization Program in Patients Chronic Non-specific Neck Pain |
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| Completed | N/A | 28 | RoW | Relaxation Exercises and Scapular Stabilization exercise program, Relaxation Exercises of cervico- scapular region | Riphah International University | Neck Pain | 12/22 | 01/23 | | |
NCT05392517: Effects of Self-mobilization Techniques in Chronic Thoracic Pain |
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| Completed | N/A | 28 | RoW | self-mobilization technique along with conventional therapy, conventional therapy | Riphah International University | Thoracic | 12/22 | 01/23 | | |
NCT05395078: Effects of Thoracic Extension Versus Thoracic Stabilization Exercises in Patients With Maigne's Thoracic Pain |
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| Completed | N/A | 32 | RoW | Conventional physical therapy treatment along with thoracic extension exercises, Conventional physical therapy treatment along with thoracic stabilization exercises | Riphah International University | Thoracic | 12/22 | 01/23 | | |
NCT05393973: Effects of Core Stability Versus Swiss Ball Exercise in Patients With Chronic Neck Pain |
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| Completed | N/A | 42 | RoW | Core stability exercises along with conventional physical therapy, Swiss ball exercises along with the conventional physical therapy protocol | Riphah International University | Neck Pain | 12/22 | 01/23 | | |
NCT05393323: Effects of Cervical Distraction Versus Cervical Traction Techniques on Upper Cervical Pain |
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| Completed | N/A | 42 | RoW | conventional physical therapy with distraction technique, conventional physical therapy with traction technique | Riphah International University | Neck Pain | 12/22 | 01/23 | | |
NCT05392036: Effects of Therapeutic Ultrasound Versus Shockwave Therapy in Medial Tibial Stress Syndrome in Recreational Runners |
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| Completed | N/A | 54 | RoW | baseline physical therapy treatment along with shockwave therapy, baseline physical therapy treatment along with therapeutic ultrasound | Riphah International University | Medial Tibial Stress Syndrome | 12/22 | 01/23 | | |
NCT05393960: Effects of Lumbosacral Mobility Program on Tight Hamstrings |
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| Completed | N/A | 78 | RoW | Lumbosacral manual therapy mobilization, lumber mobility exercises and home based self strechings program., home based self strechings program only. | Riphah International University | Hamstring Tightness | 12/22 | 01/23 | | |
NCT05404646: Effects of Thoracic Mobility Versus Stretching Exercise Program in Patients of Cervical Radiculopathy |
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| Completed | N/A | 44 | RoW | Thoracic mobility exercises with conventional physical therapy for cervical radiculopathy, Thoracic stretching exercises with conventional physical therapy for cervical radiculopathy | Riphah International University | Cervical Radiculopathy | 12/22 | 01/23 | | |
NCT04862910: Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia |
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| Completed | N/A | 52 | RoW | Kinect Based Virtual Reality Training, Control Group | Riphah International University | Postmenopausal Osteopenia | 06/23 | 06/23 | | |
NCT04583007: Expanded Access for the Prevention of Acute Attacks of 1) Hereditary Angioedema (HAE) in Children and 2) Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH) in Teenagers and Adults |
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| No Longer Available | N/A | | Europe, Canada, US | Lanadelumab 150 mg, TAK-743, SHP643, DX-2930, Lanadelumab 300 mg | Shire, Takeda Development Center Americas, Inc. | Hereditary Angioedema (HAE), Angioedema | | | | |
NCT04841902: Effects of Life Style Intervention Manual in Pre Hypertensive Sedentary Population |
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| Completed | N/A | 240 | RoW | Life Style Intervention Manual (With Exercise Under Supervision), General Advice, Life Style Intervention Manual (Home Based) | Riphah International University | Pre Hypertension | 11/23 | 12/23 | | |
NCT04949958: Effects of Exercise Based Manual in Sedentary Prediabetic Population |
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| Completed | N/A | 108 | RoW | Exercise Based Manual (Supervised), Exercise Based Manual (Home Based), Control | Riphah International University | PreDiabetes | 10/23 | 11/23 | | |
NCT06049277: Mulligan Technique Versus McKenzie Extension Exercise Chronic Unilateral Radicular Low Back Pain |
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| Completed | N/A | 32 | RoW | Mulligan techniques with manual traction, McKenzie extension exercises with manual traction | Riphah International University | Low Back Pain | 01/24 | 01/24 | | |
NCT06049251: ELDOA Technique Versus Lumbar SNAGS With Motor Control Exercises |
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| Completed | N/A | 32 | RoW | ELDOA exercises, Lumbar SNAGS and motor control exercises | Riphah International University | Low Back Pain | 01/24 | 01/24 | | |
NCT06049303: Paraffin Wax Bath With Joint Mobilization Technique in Post-traumatic Stiff Knee |
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| Completed | N/A | 34 | RoW | Paraffin wax bath therapy and Maitland joint mobilization techniques, Maitland knee joint mobilization | Riphah International University | Knee Pain Chronic | 01/24 | 01/24 | | |
NCT06049264: Thoracic Spine Manual Traction With Mobilization Versus Manipulation |
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| Completed | N/A | 34 | RoW | Thoracic spine manual traction with mobilization protocol., Thoracic manipulation protocol | Riphah International University | Thoracic | 01/24 | 01/24 | | |
NCT06049316: Scapular Stabilization vs Functional Exercises on Chronic Neck Pain |
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| Completed | N/A | 42 | RoW | Scapular stabilization exercises, Scapular functional exercises | Riphah International University | Neck Pain | 01/24 | 01/24 | | |
NCT06460870: Effect of Mojzisova Method on Pain, Menstrual Symptom and Insomnia in PD |
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| Not yet recruiting | N/A | 26 | RoW | Mojzisova method, Stretching exercises | Riphah International University | Primary Dysmenorrhea | 09/24 | 09/24 | | |
NCT06751719: Proprioceptive, Calisthenic, and Kinesthetic Exercises for Chronic Low Back Pain |
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| Recruiting | N/A | 38 | RoW | core stabilization exercises, heat therapy, proprioceptive exercises, calisthenic exercises, kinesthetic exercises | Riphah International University | Chronic Low Back Pain (CLBP) | 12/24 | 01/25 | | |
NCT06751732: Craniocervical Flexion Training for Reducing Migraine Headaches and Disability |
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| Recruiting | N/A | 38 | RoW | Craniocervical Flexion Training (CCFT), Diaphragm Respiratory Training, Cervical Mobilization and Traction, Digital Compression on Muscle Trigger Points, Passive Stretching of Neck Muscles, Instruction on Postural Correction | Riphah International University | Episodic Migraine Headache | 12/24 | 01/25 | | |
