Zhang, Tao |
NCT05175001: Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain |
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| Recruiting | 4 | 100 | RoW | Diprospan, Compound Betamethasone Injection, Ropivacaine | Affiliated Hospital of Nantong University | Chronic Pain | 06/22 | 01/23 | | |
PIONEER, NCT05029453: Apatinib Combined With Chemotherapy Versus Chemotherapy in Second-line Gastric Cancer Receiving Prior Anti-PD-1 Therapy |
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| Not yet recruiting | 4 | 60 | RoW | Apatinib | Wuhan Union Hospital, China, Jiangsu HengRui Medicine Co., Ltd. | Gastric Cancer, Randomized Controlled Study | 12/22 | 03/23 | | |
NCT05598177: Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass |
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| Completed | 4 | 64 | RoW | dexmedetomidine, Placebo | Affiliated Hospital of Nantong University | Ischemia-Reperfusion Injury | 05/23 | 12/23 | | |
NCT05922605: Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias |
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| Recruiting | 4 | 44 | RoW | S-ketamine & Ropivacaine, Ropivacaine | Tao Zhang | Postoperative Analgesia, S-ketamine, Pediatrics, Caudal Block, Hypospadias | 04/25 | 05/25 | | |
UNION, NCT04928807: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer |
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| Active, not recruiting | 3 | 231 | RoW | Short course radiotherapy sequential camrelizumab and chemotherapy | Wuhan Union Hospital, China, Jiangsu HengRui Medicine Co., Ltd. | Rectal Cancer | 03/23 | 03/26 | | |
NCT03399253: Chemotherapy Alone Versus Surgery Plus Chemotherapy for Distal Gastric Cancer With One Non-curable Factor |
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| Recruiting | 3 | 120 | RoW | surgery, chemotherapy, XELOX | Sun Yat-sen University | Gastric Cancer | 11/22 | 12/25 | | |
NCT03399110: XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC) |
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| Active, not recruiting | 3 | 1032 | RoW | Oxaliplatin, Eloxatin, Capecitabine, Xeloda | Fudan University | Gastric Cancer | 08/26 | 08/26 | | |
NCT04385550: A Study of Anlotinib Hydrochloride Capsule Combined With AK105 Injection in Subject With Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma |
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| Not yet recruiting | 3 | 528 | RoW | Anlotinib hydrochloride capsule, AK105 injection, Paclitaxel injection, Docetaxel injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma | 10/23 | 12/23 | | |
NCT04687631: Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases |
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| Recruiting | 3 | 508 | RoW | mFOLFOXIRI plus Cetuximab, mFOLFOXIRI Plus Bevacizumab | Fudan University | Colorectal Cancer, Liver Metastases | 03/25 | 09/27 | | |
BECOME2, NCT04781270: mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases |
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| Recruiting | 3 | 308 | RoW | mFOLFOXIRI regimen, mFOLFOX regimen, Bevacizumab | Fudan University | Colorectal Carcinoma, Liver Metastases | 03/24 | 03/26 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
NCT06753890: Efficacy and Safety of Changkang Granules in the Treatment of Irritable Bowel Syndrome With Predominant Diarrhea (Liver qi Affecting the Spleen Pattern) |
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| Not yet recruiting | 3 | 520 | RoW | Changkang granules, Changkang Granules placebo | Tasly Pharmaceutical Group Co., Ltd | Diarrhea-predominant Irritable Boewl Syndrome | 11/26 | 12/26 | | |
NCT05767892: YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations |
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| Not yet recruiting | 3 | 350 | RoW | YK-209A tablet, Pemetrexed+carboplatin/Cisplatin | Suzhou Puhe Pharmaceutical Technology Co., LTD | Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) | 07/25 | 12/26 | | |
NCT05180734: PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer |
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| Active, not recruiting | 3 | 878 | RoW | JS001/Placebo, Postoperative Adjuvant Chemotherapy, JS001/placebo combine with Postoperative Adjuvant Chemotherapy | Shanghai Junshi Bioscience Co., Ltd. | Gastric or Esophagogastric Junction Adenocarcinoma | 06/26 | 07/28 | | |
NCT05844150: A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC |
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| Recruiting | 2/3 | 445 | RoW | PM8002, Platinum, Atezolizumab, Etoposide | Biotheus Inc. | SCLC | 06/25 | 12/25 | | |
NCT03135652: Consolidative Radiotherapy for Colorectal Cancer Liver Metastases Receiving Surgery or Radiofrequency Ablation |
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| Withdrawn | 2 | 120 | RoW | adjuvant SBRT, radiotherapy, Chemotherapy, neoadjuvant chemotherapy and adjuvant chemotherapy | Wuhan Union Hospital, China | Radiotherapy, Colorectal Cancer, Liver Metastases | 06/21 | 06/23 | | |
MCRC-LC1, NCT03142282: Consolidative Radiotherapy Plus Maintenance Chemotherapy for Metastatic Colorectal Cancer |
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| Not yet recruiting | 2 | 200 | RoW | maintenance chemotherapy, Consolidative Radiotherapy | Wuhan Union Hospital, China | Metastatic Colorectal Cancer, Radiotherapy | 08/21 | 08/24 | | |
NCT04563975: Efficacy and Safety of Toripalimab Combined With Docetaxel or Nab-paclitaxel in Patients With Advanced Gastric Cancer |
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| Recruiting | 2 | 54 | RoW | Toripalimab, JS001, Docetaxel, Taxotere, nab-paclitaxel, AI YUE | Tao Zhang | Gastric Cancer Stage IV | 12/22 | 05/23 | | |
NCT05387681: Preoperative Short Course Radiotherapy With Envafolimab, Endostatin and SOX Regimen in Locally Advanced Gastric |
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| Not yet recruiting | 2 | 35 | NA | Envafolimab, Endostatin | Wuhan Union Hospital, China | Gastric/Gastroesophageal Junction Adenocarcinoma, Radiotherapy, Immunotherapy | 07/23 | 12/25 | | |
NCT05202236: A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastric and Colorectal Cancer Patients With FGFR Alterations Who Have Failed Standard Therapy |
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| Recruiting | 2 | 20 | RoW | pemigatinib | Wuhan Union Hospital, China | Gastric and Colorectal Cancer | 10/23 | 10/24 | | |
UNION PRECISION-I, NCT06234007: Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study |
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| Recruiting | 2 | 45 | RoW | Fruquintinib, Adebrelimab, Oxaliplatin, Capecitabine | Wuhan Union Hospital, China, Renmin Hospital of Wuhan University | Locally Advanced Rectal Cancer | 12/24 | 12/27 | | |
NAUTICALCRC, NCT05004350: A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer. |
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| Active, not recruiting | 2 | 103 | RoW | Encorafenib, Braftovi®, PF-07263896, W0090, LGX818, ONO-7702, Cetuximab, Erbitux®, C225, FOLFIRI, Folinic acid + Fluorouracil + Irinotecan | Pierre Fabre Medicament, Merck KGaA, Darmstadt, Germany | BRAF V600E, Metastatic Colorectal Cancer | 12/23 | 01/25 | | |
NCT06487429: Short Course Radiotherapy With Sequential Disitamab Vedotin Combined With S-1 and Sintilimab as Whole Course Neoadjuvant Therapy for HER2 Expressed Locally Progressive Gastric Cancer |
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| Recruiting | 2 | 28 | RoW | Short range radiotherapy with sequential Disitamab Vedotin combined with S-1 and xindilizumab | Wuhan Union Hospital, China, RemeGen Co., Ltd. | Gastric Cancer | 05/26 | 05/28 | | |
NCT03941574: A Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard Therapy |
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| Recruiting | 2 | 108 | RoW | HLX10 | Shanghai Henlius Biotech | MSI-H Solid Malignant Tumor | 05/24 | 06/26 | | |
AK112-IIT-004, NCT06491472: Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer |
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| Recruiting | 2 | 36 | RoW | Ivonescimab, AK112/SMT112, Gemcitabine, Nab paclitaxel, SBRT | Wuhan Union Hospital, China, Akesobio | Pancreatic Cancer | 07/26 | 07/27 | | |
NCT06542588: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC |
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| Recruiting | 2 | 29 | RoW | HLX07(anti EGFR antibody) and Serplulimab(anti PD-1 antibody), CAPOX | Wuhan Union Hospital, China | Rectal Cancer | 12/25 | 12/26 | | |
NCT06111274: A Phase 2 Study of ABSK021 in Patients With Advanced Pancreatic Cancer |
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| Recruiting | 2 | 82 | RoW | Pimicotinib (ABSK021), Gemcitabine, nab-Pacilitaxel, Toripalimab | Abbisko Therapeutics Co, Ltd | Advanced Pancreatic Cancer | 12/25 | 12/26 | | |
NCT05747716: SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody for Third-line Treatment in mCRC |
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| Not yet recruiting | 2 | 44 | RoW | SBRT, Fruquintinib, Cadonilimab | Wuhan Union Hospital, China | Metastatic Colorectal Cancer | 12/26 | 12/26 | | |
NCT04231552: Preoperative Short Course Radiotherapy With Chemotherapy and Camerelizumab in Locally Advanced Rectal Cancer |
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| Active, not recruiting | 1/2 | 30 | RoW | Camrelizumab, Radiotherapy with CAPOX+ Camrelizumab following surgical therapy | Wuhan Union Hospital, China | Rectal Cancer, Radiotherapy, Immunotherapy | 09/20 | 09/23 | | |
NCT06266143: A Trial of Y101D in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Advanced Pancreatic Cancer |
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| Active, not recruiting | 1/2 | 71 | RoW | Y101D | Wuhan YZY Biopharma Co., Ltd. | Advanced Pancreatic Adenocarcinoma | 07/24 | 12/24 | | |
NCT05653180: IBI310 in Combination With Sintilimab in Patients With Advanced Biliary Tract Cancer |
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| Recruiting | 1/2 | 20 | RoW | IBI310, sintilimab, IBI308 | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Biliary Tract Cancer | 12/23 | 06/24 | | |
NCT05260385: To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors |
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| Recruiting | 1/2 | 133 | RoW | KC1036 | Beijing Konruns Pharmaceutical Co., Ltd. | Digestive System Tumors | 10/25 | 12/25 | | |
NCT05747729: A Single-arm, Open-label, Clinical Trial of Surufatinib/Serplulimab/Platinum/Etoposide in Neuroendocrine Carcinoma. |
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| Not yet recruiting | 1/2 | 60 | RoW | Surufatinib and Serplulimab | Wuhan Union Hospital, China | Neuroendocrine Carcinoma | 02/25 | 02/26 | | |
| Recruiting | 1/2 | 364 | RoW | SHR-A1811 combined with Pyrotinib., SHR-A1811 combined with other antitumor therapies | Jiangsu HengRui Medicine Co., Ltd. | HER2-expressing Advanced Solid Tumors | 11/26 | 12/26 | | |
NCT06144385: A Phase 1, Single-arm, Open-label, Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma |
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| Recruiting | 1 | 20 | RoW | CAR-GPC3 T cells, JWCAR204 | Shanghai Ming Ju Biotechnology Co., Ltd. | Liver Carcinoma, Hepatic Cell Carcinoma | 03/24 | 12/24 | | |
NCT06166472: A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor |
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| Not yet recruiting | 1 | 72 | RoW | AK132 | Akeso | Advanced Malignant Solid Tumor | 04/26 | 07/26 | | |
NCT05169697: A Study to Assess YH002 in Combination with YH001 in Subjects with Advanced Solid Tumors |
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| Completed | 1 | 6 | RoW | A:YH002+YH001, B:YH002+YH001, YH002+YH001 | Eucure (Beijing) Biopharma Co., Ltd | Advanced Solid Tumor | 07/23 | 07/23 | | |
NCT05441046: Genakumab Alone and in Combination With Tislelizumab in Patients With Advanced Malignant Solid Tumors |
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| Recruiting | 1 | 120 | RoW | Genakumab, Tislelizumab | GeneScience Pharmaceuticals Co., Ltd. | Malignant Solid Tumors | 06/24 | 03/25 | | |
| Recruiting | 1 | 556 | RoW | IBI363 + chemotherapy, IBI363 + Investigator's Choice SOC | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Malignancies | 06/25 | 12/26 | | |
NCT06484556: NW-301 TCR-T in Patients With Advanced Solid Tumor |
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| Recruiting | 1 | 9 | RoW | NW-301V, NW-301D | Tao Zhang, Neowise Biotechnology | Tumor, Solid | 06/26 | 06/27 | | |
NCT06437873: Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3/T4 FTC |
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| Completed | N/A | 2957 | NA | Total Thyroidectomy (TT), Radioactive iodine treatment(RAIT) | Dezhou Hospital Qilu Hospital of Shandong University | Follicular Thyroid Cancer, SEER Database Analysis | 12/20 | 05/24 | | |
| Completed | N/A | 3068 | NA | Different Pathological Types (FTC vs PTC), Different Pathological Types | Dezhou Hospital Qilu Hospital of Shandong University | Pediatric and Adolescent Differentiated Thyroid Carcinoma, SEER Database Analysis | 12/20 | 08/24 | | |
NCT03426514: Three-port Versus Conventional Laparoscopic Surgery for Colorectal Cancer |
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| Recruiting | N/A | 282 | RoW | Three-port Laparoscopic Surgery, Conventional Laparoscopic Surgery | Ruijin Hospital | Colorectal Cancer | 03/20 | 03/25 | | |
NCT05280860: Effect of Bilateral RSB on Postoperative Delirium in Elderly Patients Undergoing Laparoendoscopic Single-site Surgery |
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| Recruiting | N/A | 320 | RoW | ultrasound-guided bilateral rectus sheath block | Affiliated Hospital of Nantong University | Delirium in Old Age, Hernia, Inguinal, Cholecystolithiasis | 12/22 | 12/22 | | |
NCT04360577: Acupuncture for QoL and Symptoms in Gastric Cancer During Adjuvant Chemotherapy |
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| Completed | N/A | 240 | RoW | acupuncture | Guangzhou University of Traditional Chinese Medicine, First Affiliated Hospital, Sun Yat-Sen University, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Sixth Affiliated Hospital, Sun Yat-sen University, Southern Medical University, China, Guangdong Provincial People's Hospital, The First Affiliated Hospital of Guangzhou Medical University, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Fifth Affiliated Hospital, Sun Yat-Sen University, First People's Hospital of Foshan, Yuebei People's Hospital | Stomach Neoplasms | 03/23 | 05/23 | | |
NCT05325827: Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery |
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| Recruiting | N/A | 44 | RoW | ultrasound-guided high fascia iliaca compartment block | Affiliated Hospital of Nantong University | Knee Disease, Delirium | 12/22 | 02/23 | | |
NCT05533970: Ultrasound-guided H-FICB for Arthroscopic Knee Surgery: What is the Optimal Dose of Dexmedetomidine? |
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| Completed | N/A | 120 | RoW | ultrasound-guided high fascia iliaca compartment block | Affiliated Hospital of Nantong University | Knee Disease, Quality of Recovery | 12/22 | 01/23 | | |
NCT06141421: A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Colorectal Surgeries(SPiM-RWS-CR) |
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| Completed | N/A | 15 | RoW | procedure | Ruijin Hospital | Single-Port Colorectal Surgeries | 08/24 | 08/24 | | |
NCT05820503: Effect of Nerve Block Under Ultrasound on Postoperative Prognosis in Children |
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| Completed | N/A | 112 | RoW | Ultrasound-guided lower abdominis rectus sheath block, Local anesthesia infiltration | Affiliated Hospital of Nantong University | Quality of Recovery | 10/23 | 10/23 | | |
NCT06189183: Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection |
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| Recruiting | N/A | 50 | RoW | Adjuvant Hypofractionation Radiotherapy | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Thymus Neoplasms | 12/30 | 12/40 | | |
| Recruiting | N/A | 174 | RoW | Upadacitinib | Xiang Gao | Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis | 12/28 | 12/28 | | |
NCT06508008: Rapid and Safe Sputum Suction Method Validation |
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| Recruiting | N/A | 900 | RoW | continuous negative pressure suction, Intermittent negative pressure sputum suction through oral pharyngeal airway | Affiliated Hospital of Nantong University | Sputum | 07/24 | 08/24 | | |
NCT06163092: Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage |
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| Not yet recruiting | N/A | 175 | RoW | | Chinese University of Hong Kong | Recurrent Miscarriage | 01/26 | 01/27 | | |
NCT06417749: MIND Diet and Cognitive Function in Middle-aged and Older Adults |
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| Not yet recruiting | N/A | 1200 | RoW | Control arm, Intervention arm | Zhejiang University, Shandong University | Cognitive Function, Dementia | 05/25 | 10/25 | | |
NCT05613049: Confounding Factors of Chronic Endometritis in Women With Reproductive Failure |
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| Recruiting | N/A | 720 | RoW | | Chinese University of Hong Kong | IVF | 07/27 | 01/28 | | |