Universitätsklinikum Hamburg Eppendorf
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 74 Trials 
778 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Miller, David S
NCT05850494: Study to Assess Bronchospasm Potentially Induced by HFO vs HFA MDI in Participants With Well/Partially Controlled Asthma

Completed
3
52
US
HFA MDI, Propellant in MDI, HFO MDI
AstraZeneca
Asthma
08/23
08/23
FORCE2, NCT05292586: A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared to CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid

Completed
3
610
US
Beclomethasone Dipropionate/Formoterol Fumarate, BDP/FF, Beclomethasone Dipropionate, BDP
Chiesi Farmaceutici S.p.A.
Asthma
06/24
06/24
ACHIEVE, NCT03020303 / 2020-001882-36: Aldosterone BloCkade for Health Improvement EValuation in End-stage Renal Disease

Recruiting
3
2750
Europe, Canada, RoW
Spironolactone 25Mg Tablet, Placebo Oral Tablet
Population Health Research Institute, Canadian Institutes of Health Research (CIHR)
Endstage Renal Disease
07/25
04/26
ENGOT-EN20, NCT05611931 / 2022-002540-42: Selinexor in Maintenance Therapy After Systemic Therapy for Participants with P53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Jul 2024 - Dec 2024: Top-line data from XPORT-EC trial in participants with TP53 wild type endometrial cancer
Recruiting
3
220
Europe, Canada, US, RoW
Selinexor, KPT-330, Matching Placebo for selinexor
Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group
Endometrial Cancer
01/25
01/28
NCT03712605: Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial

Hourglass Jan 2023 - Dec 2023 : Results for stage I-III MCC that has been completely removed by surgery
Active, not recruiting
3
280
US
Best Practice, standard of care, standard therapy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
National Cancer Institute (NCI)
Pathologic Stage I Cutaneous Merkel Cell Carcinoma AJCC v8, Pathologic Stage II Cutaneous Merkel Cell Carcinoma AJCC v8, Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
12/25
12/25
NRG-GY019, NCT04095364: Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recruiting
3
450
Europe, Canada, US, RoW
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Imaging Technique, Diagnostic Imaging Technique, Image Type, Imaging, Imaging (procedure), imaging procedure, Imaging Procedures, imaging type, IMAGING_METHOD, imaging_type, Medical Imaging, Type of imaging, Letrozole, CGS 20267, Femara, Fempro, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat
NRG Oncology, National Cancer Institute (NCI)
Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8, Stage II Ovarian Cancer AJCC v8, Stage II Primary Peritoneal Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
02/27
02/28
GOG-3026, NCT03673124: Ribociclib and Letrozole Treatment in Ovarian Cancer

Active, not recruiting
2
51
US
Ribociclib, Letrozole
Gynecologic Oncology Group, Novartis
Low Grade Serous Carcinoma
12/23
12/24
NCI-2017-01672, NCT03660826: Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active, not recruiting
2
286
Canada, US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspirate, BONE MARROW, LIQUID, Human Bone Marrow Aspirate, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Capivasertib, AZD 5363, AZD-5363, AZD5363, Truqap, Cediranib, AZ-D2171, AZD 2171, AZD2171, Cediranib Maleate, AZD2171 Maleate, Recentin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Durvalumab, Imfinzi, Immunoglobulin G1, Anti-(Human Protein B7-H1) (Human Monoclonal MEDI4736 Heavy Chain), Disulfide with Human Monoclonal MEDI4736 Kappa-chain, Dimer, MEDI 4736, MEDI-4736, MEDI4736, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Olaparib, AZD 2281, AZD-2281, AZD2281, KU 0059436, KU-0059436, KU0059436, Lynparza, Olanib, Olaparix, PARP Inhibitor AZD2281
National Cancer Institute (NCI), NRG Oncology
Endometrial Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Endometrioid Adenocarcinoma, Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
12/24
01/26
ENGOT-ov60, NCT04625270 / 2020-004264-26: A Study of Avutometinib (VS-6766) V. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer with and Without a KRAS Mutation

Active, not recruiting
2
225
Europe, Canada, US
avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063
Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation
Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer
11/24
12/26
SURPASS-3, NCT05601752 / 2022-003176-16: ADP-A2M4CD8 Monotherapy and in Combination with Nivolumab in HLA-A2+ Subjects with MAGE-A4 Positive Ovarian Cancer

Active, not recruiting
2
66
Europe, Canada, US
Autologous genetically modified ADP-A2M4CD8 cells, Autologous genetically modified ADP-A2M4CD8 cells in combination with Nivolumab
Adaptimmune, GOG Foundation
Ovarian Cancer
08/26
08/26
SGNDV-005, NCT06003231: A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Active, not recruiting
2
122
Europe, Canada, US, RoW
disitamab vedotin, RC48, RC48-ADC
Seagen Inc.
Carcinoma, Squamous Cell of Head and Neck, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Endometrial Neoplasms
05/26
05/28
XTX202-01, NCT05052268 / 2022-003078-21: XTX202 in Patients With Advanced Solid Tumors

Active, not recruiting
1/2
189
US
XTX202
Xilio Development, Inc., Xilio Development, Inc
Advanced Solid Tumor
02/26
02/26
PYNNACLE, NCT04585750: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation

Recruiting
1/2
230
Europe, US, RoW
PC14586, rezatapopt, pembrolizumab, KEYTRUDA®, MK-3475, KEYNOTE-D79, MK-3475-D79
PMV Pharmaceuticals, Inc, Merck Sharp & Dohme LLC
Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Prostate Cancer, Colorectal Cancer, Breast Cancer, Other Cancer, Locally Advanced, Head and Neck Cancer
03/26
07/26
ACR-368-201, NCT05548296: A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma

Recruiting
1/2
390
US
ACR-368, prexasertib, Gemcitabine, OncoSignature
Acrivon Therapeutics, GOG Foundation
Platinum-resistant Ovarian Cancer, Endometrial Adenocarcinoma, Urothelial Carcinoma
07/26
12/27
NCT03272464: INCB039110 in Combination With Dabrafenib and Trametinib in Patients With BRAF-mutant Melanoma and Other Solid Tumors.

Terminated
1
1
US
Trametinib, Mekinist, Dabrafenib, Tafinlar, INCB039110, Itacitinib
Massachusetts General Hospital, Incyte Corporation
Melanoma
07/19
12/19
NCT03843957: Effectiveness and Implementation of mPATH-CRC

Completed
N/A
77145
US
mPATH-CRC, mPATH-Checkin, "high touch" Implementation strategy, "low touch" Implementation Strategy
Wake Forest University Health Sciences, National Cancer Institute (NCI)
Colorectal Cancer, Cancer, Rectum Cancer, Colon Cancer
08/22
03/23
mPATH-Lung, NCT04083859: Digital Outreach Intervention for Lung Cancer Screening

Completed
N/A
26998
US
mPATH-Lung, Lung health video
Wake Forest University Health Sciences, University of North Carolina, Chapel Hill, National Cancer Institute (NCI)
Lung Cancer
09/23
09/24
NCT06241768: Feasibility of a Colorectal Cancer Screening Web App in Primary Care Patients

Not yet recruiting
N/A
1000
US
mPATH-CRC Web app
Digital Health Navigation Solutions, Inc, Wake Forest University Health Sciences, National Cancer Institute (NCI)
Colorectal Cancer Screening
05/24
06/24
NF1-TED, NCT06515860: Neurofibromatosis Type 1 Tumor Early Detection Study

Recruiting
N/A
1000
US
Liquid biopsy for MPNST development
David Miller
Neurofibromatosis Type 1, Neurofibromatosis 1, Plexiform Neurofibroma, Plexiform Neurofibromas, Malignant Peripheral Nerve Sheath Tumor, Malignant Peripheral Nerve Sheath Tumors, Atypical Neurofibroma
07/30
07/30
SAMBA, NCT04680611: Severe Asthma, MepolizumaB and Affect: Study

Recruiting
N/A
120
Europe
no study intervention. Patients receive standard clinical care, no intervention. observational study
University Hospital Southampton NHS Foundation Trust, Portsmouth Hospitals NHS Trust, University of Derby
Severe Eosinophilic Asthma, Psychological Distress, Anxiety, Depression, Psychological Stress, Psychological Adjustment, Psychological Disorder, Psychosocial Problem, Psychosocial Stressor, Psychological, Emotions, Emotional Disorder, Emotional Dysfunction, Emotional Distress, Adjustment, Adjustment, Emotional, Coping Behavior
12/24
12/24
mPATH-Cloud, NCT06441487: for Colorectal Cancer Screening

Not yet recruiting
N/A
1000
US
Mobile Health Decision Support, mPATH™-Cloud, Usual care
UNC Lineberger Comprehensive Cancer Center, National Institutes of Health (NIH), National Cancer Institute (NCI)
Colorectal Cancer
07/27
01/29
NCT03141021: Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Recruiting
N/A
1050
Europe, Canada, Japan, US, RoW
Washington University School of Medicine, Boston's Children Hospital
Malignant Peripheral Nerve Sheath Tumors
04/53
04/53
SOROCk, NCT04251052: A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
N/A
2262
Canada, US, RoW
Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, bilateral salpingo-oophorectomy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Transvaginal Ultrasound, transvaginal sonography, TVS, TVU, Ultrasound Imaging, 2-Dimensional Grayscale Ultrasound Imaging, 2-Dimensional Ultrasound Imaging, 2D-US, Ultrasonography, Ultrasound, Ultrasound Test, Ultrasound, Medical, US
NRG Oncology, National Cancer Institute (NCI)
Ovarian Carcinoma
06/36
06/37
Viskochil, David
COMPASS, NCT05371613 / 2021-005200-35: A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) Vs Idursulfase in Pediatric and Young Adult Participants with Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)

Recruiting
2/3
54
Europe, Canada, US, RoW
tividenofusp alfa, idursulfase
Denali Therapeutics Inc.
Mucopolysaccharidosis II
12/25
12/25
NCT05005845: NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Completed
2
199
US
NFX-179 gel, NFX-179 topical gel, Vehicle gel, NFX-179 vehicle gel
NFlection Therapeutics, Inc.
Cutaneous Neurofibroma, Neurofibromatosis 1
10/23
10/23
NCT05238324: Safety and Efficacy of HMI-203 in ERT-Treated Adults With MPS II

Withdrawn
1
9
Canada, US
Genetic HMI-203
Homology Medicines, Inc
Mucopolysaccharidosis II
10/24
01/29
NCT05795361: Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

Available
N/A
Europe, US, RoW
Idursulfase-IT, HGT-2310, TAK-609
Takeda
Hunter Syndrome
 
 
Klose, Hans
NCT03626688 / 2018-001187-33: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Recruiting
3
1000
Europe, Canada, US, RoW
Ralinepag, APD811, Placebo
United Therapeutics
PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
12/25
12/25
PEGASUS, NCT03051763: The Effects of Commercial Air Travel on Patients Suffering From Pulmonary Hypertension

Recruiting
N/A
1000
Europe
University of Giessen, Universitätsklinikum Hamburg-Eppendorf, DRK Kliniken Berlin Köpenick, Berlin, Germany, University Hospital, Zürich, University Hospital Carl Gustav Carus
Pulmonary Hypertension, Pulmonary Arterial Hypertension
12/21
05/22
Schafhausen, Philippe
HARBOR, NCT04910685 / 2020-005173-28: () Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Recruiting
2/3
463
Europe, US, RoW
Elenestinib, BLU-263, Placebo
Blueprint Medicines Corporation
Indolent Systemic Mastocytosis, Monoclonal Mast Cell Activation Syndrome, Smoldering Systemic Mastocytosis
06/28
06/28
NCT06062420: A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202

Recruiting
2
360
Europe, Canada, Japan, US, RoW
Dostarlimab, Belrestotug, Nelistotug, GSK4381562
GlaxoSmithKline, iTeos Therapeutics
Neoplasms, Head and Neck
05/27
05/27
Putensen, Christian
ARISS, NCT03869385: Albumin Replacement Therapy in Septic Shock

Terminated
3
440
Europe
Albutein® 200 g/L or Plasbumin® 20, Human Albumin 20%
Jena University Hospital, German Research Foundation, Instituto Grifols, S.A., University Hospital Goettingen, SepNet - Critical Care Trials Group, Center for Sepsis Control and Care, Germany
Septic Shock
07/22
06/23
HerpMV, NCT06134492: Acyclovir in Mechanically Ventilated Patients With Pneumonia and HSV-1 in BAL

Recruiting
3
710
Europe
Acyclovir, Aciclovir
Jena University Hospital
Pneumonia, Viral, Ventilator Associated Pneumonia, Community-acquired Pneumonia, Herpes Simplex, Hospital-acquired Pneumonia
07/26
12/26
NCT03567577 / 2017-003855-47: Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

Recruiting
2
95
Europe
Solnatide 25 mg powder for reconstitution for solution for inhalation, AP301, 0.9% Saline Solution
Apeptico Forschung und Entwicklung GmbH
ARDS
12/24
12/24
PReSPON, NCT04228471: Early PReserved SPONtaneous Breathing Activity in Mechanically Ventilated Patients With ARDS

Recruiting
N/A
840
Europe
spontaneous breathing activity during APRV, No spontaneous breathing activity
University Hospital, Bonn, European Society of Anaesthesiology
Respiratory Distress Syndrome, Adult
02/24
07/24
DigiSep, NCT04571801: Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics

Recruiting
N/A
410
Europe
Standard diagnostics, Next Generation Sequencing (NGS)
University Hospital, Essen, Noscendo GmbH, Germany, Health Economics and Health Care Management, Bielefeld University, Institute of Medical Biometry and Informatics, University of Heidelberg, Coordination Centre for Clinical Trials (KKS), University of Heidelberg, Department of Infectious Diseases, University Hospital Essen, Center for Infectious Diseases and Infection Control, Jena University Hospital, Department of Anesthesiology, Heidelberg University Hospital, AOK Health Insurance, Rheinland, Hamburg, Barmer Health Insurance, Germany, Techniker Health Insurance, Germany
Sepsis, Septic Shock
02/24
08/24
Heesen, Christoph
NCT03674099: Imatinib for Multiple Sclerosis (MS) Relapses

Recruiting
2
200
Europe
Imatinib Mesylate, Methylprednisolone
Tomas Olsson, The Swedish Research Council
Multiple Sclerosis
12/22
07/23
CALLIPER, NCT05054140 / 2021-000048-23: Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis

Active, not recruiting
2
450
Europe, Canada, US, RoW
IMU-838, Vidofludimus calcium, Placebo matching IMU-838, Placebo Arm
Immunic AG
Multiple Sclerosis
01/25
01/25
RED4MS, NCT06430671 / 2022-000801-28: Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis

Recruiting
1/2
135
Europe
CLS12311 low, CLS12311 medium, CLS12311 high, uncoupled RBCs
Cellerys AG, Novartis, Scope International AG, Tetec AG, Jung Diagnostics GmbH
Relapsing-remitting Multiple Sclerosis (RRMS)
08/26
03/27
NCT02740361: Online Program to Reduce Depression in MS

Active, not recruiting
N/A
400
Europe, US
Deprexis, DeprexisPlus
Charite University, Berlin, Germany, National Multiple Sclerosis Society, Universitätsklinikum Hamburg-Eppendorf, Cedars-Sinai Medical Center, University of Missouri, Kansas City, Penn State University, King's College London, University Medical Center Goettingen, NeuroCure Clinical Research Center, Charite, Berlin
Multiple Sclerosis
01/21
12/21
UMIMS, NCT03872583: Understanding Magnetic Resonance Imaging in Multiple Sclerosis

Completed
N/A
120
Europe
Understanding MRI in MS (website), Control website
Universitätsklinikum Hamburg-Eppendorf, Sanofi
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Clinically Isolated Syndrome
12/22
12/22
POWER@MS1, NCT03968172: Interactive Web Platform for EmPOWERment in Early Multiple Sclerosis

Completed
N/A
234
Europe
EBBC programme, Control group programme
Universitätsklinikum Hamburg-Eppendorf, Charite University, Berlin, Germany, University of Cologne, University Medical Center Goettingen, Heinrich-Heine University, Duesseldorf, Gaia AG, BKK Dachverband e.V., Deutsche Multiple Sklerose Gesellschaft (DMSG)
Multiple Sclerosis
04/23
04/23
PExMS, NCT04236544: Patient Experiences of Multiple Sclerosis

Not yet recruiting
N/A
55
NA
PExMS and DECIMS-Wiki, DECIMS-Wiki
Universitätsklinikum Hamburg-Eppendorf, Marianne-Strauss-Klinik, Berg, Germany, Gesundheitszentrum St. Johannes Hospital, Bonn, Germany, University Hospital Cologne, Cologne, Germany, Rechts der Isar Hospital, Munich, Germany, University Medical Center Schleswig-Holstein, Kiel, Germany
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Patient Engagement, Self Efficacy
12/25
12/25
Chen, Jing X
NCT04766307: A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2

Recruiting
4
1100
RoW
Interleukin-2, IL-2
Beijing Chest Hospital
Tuberculosis, Pulmonary
12/21
12/21
NCT06406205: A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis

Recruiting
3
270
RoW
Voclosporin（QL1074）, Placebo
Qilu Pharmaceutical Co., Ltd.
Lupus Nephritis
06/27
06/28
MELATORCH, NCT03430297: A Randomized, Controlled, Multi-center, Phase III Clinical Study to Investigate Recombinant Humanized PD-1 Monoclonal Antibody Injection (JS001) Versus Dacarbazine as the 1st-line Therapy for Unresectable or Metastatic Melanoma

Completed
3
256
RoW
JS001 240mg Q2W, Dacarbazine 1000mg/m2 Q3W
Shanghai Junshi Bioscience Co., Ltd.
Metastatic Melanoma, Unresectable Melanoma
07/23
11/23
NCT06329622: Effect of Ketosteril on Sarcopenia in Patients With Chronic Kidney Disease

Recruiting
3
58
RoW
low-protein diet + Ketosteril, low-protein diet
Huashan Hospital
Chronic Kidney Disease, Sarcopenia
06/26
06/26
TAK-620-2004, NCT05319353 / 2021-004279-15: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)

Active, not recruiting
3
80
Europe, Japan, US, RoW
Maribavir, TAK-620
Takeda, Takeda Development Center Americas, Inc.
Cytomegalovirus (CMV)
01/27
01/27
NCT05602194: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Recruiting
3
440
Canada, US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Calaspargase Pegol, Asparaginase (Escherichia coli Isoenzyme II), Conjugate with alpha-(((2,5-Dioxo-1-pyrrolidinyl)oxy)carbonyl)-omega-methoxypoly(oxy-1,2-ethanediyl), Asparlas, Calaspargase Pegol-mknl, EZN-2285, SC-PEG E. Coli L-Asparaginase, Succinimidyl Carbonate Monomethoxypolyethylene Glycol E. coli L-Asparaginase, Levocarnitine, Carnitor, L-carnitine, Pegaspargase, L-Asparaginase with Polyethylene Glycol, Oncaspar, Oncaspar-IV, PEG-Asparaginase, PEG-L-Asparaginase, PEG-L-Asparaginase (Enzon - Kyowa Hakko), PEGLA, Polyethylene Glycol L-Asparaginase, Polyethylene Glycol-L-Asparaginase, Quality-of-Life Assessment, Quality of Life Assessment
Children's Oncology Group
B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like, Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia, T Acute Lymphoblastic Leukemia
06/28
12/28
NCT04293562: A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Active, not recruiting
3
1400
Canada, US, RoW
Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic, Allogeneic Hematopoietic Cell Transplantation, Allogeneic Stem Cell Transplantation, HSC, HSCT, Stem Cell Transplantation, Allogeneic, Asparaginase, ASP-1, Asparaginase II, Asparaginase-E.Coli, Colaspase, Elspar, Kidrolase, L-Asnase, L-ASP, L-Asparaginase, L-Asparagine Amidohydrolase, Laspar, Lcf-ASP, Leucogen, Leunase, MK-965, Paronal, Re-82-TAD-15, Serasa, Spectrila, Asparaginase Erwinia chrysanthemi, Asparaginase Erwinia chrysanthemi (Recombinant)-rywn, Asparaginase Erwinia chrysanthemi, Recombinant-rywn, Asparaginase Erwinia chrysanthemi-rywn, Crisantaspase, Crisantaspase Biobetter JZP-458, Crisantaspasum, Enrylaze, Erwinase, Erwinaze, JZP 458, JZP-458, JZP458, PF743, RC-P JZP-458, Recombinant Asparaginase erwinia chrysanthemi JZP-458, Recombinant Crisantaspase JZP-458, Recombinant Erwinia asparaginase JZP-458, Rylaze, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Cogstate Assessment Battery, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Cytarabine, .beta.-Cytosine arabinoside, 1-.beta.-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-.beta.-D-Arabinofuranosylcytosine, 1-Beta-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-Beta-D-arabinofuranosylcytosine, 1.beta.-D-Arabinofuranosylcytosine, 2(1H)-Pyrimidinone, 4-Amino-1-beta-D-arabinofuranosyl-, 2(1H)-Pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl-, Alexan, Ara-C, ARA-cell, Arabine, Arabinofuranosylcytosine, Arabinosylcytosine, Aracytidine, Aracytin, Aracytine, Beta-Cytosine Arabinoside, CHX-3311, Cytarabinum, Cytarbel, Cytosar, Cytosine Arabinoside, Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Erpalfa, Starasid, Tarabine PFS, U 19920, U-19920, Udicil, WR-28453, Daunorubicin Hydrochloride, Cerubidin, Cerubidine, Cloridrato de Daunorubicina, Daunoblastin, Daunoblastina, Daunoblastine, Daunomycin Hydrochloride, Daunomycin, hydrochloride, Daunorubicin.HCl, Daunorubicini Hydrochloridum, FI-6339, Ondena, RP-13057, Rubidomycin Hydrochloride, Rubilem, Dexrazoxane Hydrochloride, Cardioxane, Totect, Zinecard, Etoposide, Demethyl Epipodophyllotoxin Ethylidine Glucoside, EPEG, Lastet, Toposar, Vepesid, VP 16, VP 16-213, VP 16213, VP-16, VP-16-213, VP-16213, VP16, VP16213, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Gemtuzumab Ozogamicin, Calicheamicin-Conjugated Humanized Anti-CD33 Monoclonal Antibody, CDP-771, CMA-676, gemtuzumab, hP67.6-Calicheamicin, Mylotarg, WAY-CMA-676, Gilteritinib Fumarate, ASP-2215 Hemifumarate, ASP2215 Hemifumarate, Gilteritinib Hemifumarate, Xospata, Liposome-encapsulated Daunorubicin-Cytarabine, CPX 351, CPX-351, CPX351, Cytarabine and Daunorubicin Liposomal, Cytarabine-Daunorubicin Liposome for Injection, Daunorubicin and Cytarabine (Liposomal), Liposomal AraC-Daunorubicin CPX-351, Liposomal Cytarabine-Daunorubicin, Liposome-encapsulated Combination of Daunorubicin and Cytarabine, Vyxeos, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Mitoxantrone Hydrochloride, CL 232315, DHAD, DHAQ, Dihydroxyanthracenedione Dihydrochloride, Mitoxantrone Dihydrochloride, Mitoxantroni Hydrochloridum, Mitozantrone Hydrochloride, Mitroxone, Neotalem, Novantrone, Onkotrone, Pralifan, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Therapeutic Hydrocortisone, Aeroseb-HC, Barseb HC, Barseb-HC, Cetacort, Cort-Dome, Cortef, Cortenema, Cortifan, Cortisol, Cortispray, Cortril, Dermacort, Domolene, Eldecort, Hautosone, Heb-Cort, Hydrocortisone, Hydrocortone, Hytone, Komed-HC, Nutracort, Proctocort, Rectoid
Children's Oncology Group, National Cancer Institute (NCI)
Acute Myeloid Leukemia
09/27
09/27
NACI-CERV-003, NCT06288373: Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC

Recruiting
2/3
440
RoW
Camrelizumab, Cisplatin, Nab paclitaxel, Radical surgery, external beam radiation therapy (EBRT) + brachytherapy
Tongji Hospital, Southwest Hospital, China, Women Hospital, School of Medicine, Zhejiang University, Anhui Provincial Cancer Hospital, Sichuan Cancer Hospital and Research Institute, Qilu Hospital of Shandong University, Beijing Friendship Hospital, Tianjin Medical University General Hospital, West China Second University Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Xiangya Hospital of Central South University, Gansu Provincial Maternal and Child Health Care Hospital, Zhejiang Cancer Hospital, Shengjing Hospital, Cancer Hospital of Guangxi Medical University
Cervical Cancer, Locally Advanced Cervical Cancer, Concurrent Chemoradiotherapy, Neoadjuvant Chemoimmunotherapy
03/31
03/31
NCT04910126: Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue Sarcoma

Recruiting
2
84
RoW
Camrelizumab, C, Adriamycin, A
Wuhan Union Hospital, China
Soft Tissue Sarcoma, Neoplasms, Connective and Soft Tissue, Sarcoma Metastatic, Sarcoma,Soft Tissue
01/23
11/23
NCT05114603: A Phase II Clinical Trial to Evaluate HLX208 in Advanced Melanoma Patients With BRAF V600 Mutation

Recruiting
2
30
RoW
HLX208
Shanghai Henlius Biotech
Advanced Melanoma
08/23
08/24
NCT06367075: A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

Not yet recruiting
2
53
NA
Cadonilimab, AK104, Adriamycin, Doxorubicin
Wuhan Union Hospital, China, Sun Yat-sen University, Xiangya Hospital of Central South University, Yunnan Cancer Hospital, The Affiliated Hospital Of Guizhou Medical University, First Affiliated Hospital of Guangxi Medical University
Advanced Soft-tissue Sarcoma
03/27
03/29
NACI-CERV-005, NCT06289062: Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer

Recruiting
2
40
RoW
Camrelizumab, Cisplatin, Nab paclitaxel, biopsy
Tongji Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Women Hospital, School of Medicine, Zhejiang University, Third Military Medical University, Beijing Friendship Hospital, Sichuan Cancer Hospital and Research Institute, Tianjin Medical University, West China Second University Hospital, Xiangya Hospital of Central South University, Qilu Hospital of Shandong University, Gansu Cancer Hospital, Zhejiang Cancer Hospital, Shengjing Hospital, Anhui Provincial Cancer Hospital
Cervical Cancer, Neoadjuvant Chemoimmunotherapy, Fertility Preservation
12/25
12/30
NCT06289751: Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer

Recruiting
2
50
RoW
Cadonilimab, Cadonilimab Injection, AK104, Paclitaxel-albumin, Injectable paclitaxel (albumin bound), Cisplatin, Cisplatin injection, Extrafascial hysterectomy, Radical hysterectomy, Cone biopsy
Tongji Hospital, The First Affiliated Hospital of China University of Science and Technology (Anhui Provincial), Women Hospital, School of Medicine, Zhejiang University, Southwest Hospital, China, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sichuan Cancer Hospital and Research Institute, Qilu Hospital of Shandong University, Beijing Friendship Hospital, Tianjin Medical University, West China Second University Hospital, Xiangya Hospital of Central South University, Gansu Provincial Maternal and Child Health Care Hospital, Zhejiang Cancer Hospital, Shengjing Hospital
Cervical Cancer, Neoadjuvant Chemoimmunotherapy, Radical Hysterectomy, Extrafascial Hysterectomy
03/26
01/31
NACI-CERV-002, NCT06288360: Neoadjuvant Immunochemotherapy in PD-L1-negative LACC

Recruiting
2
40
RoW
Camrelizumab, SHR-1210, Paclitaxel-albumin, Injectable paclitaxel (albumin bound), Cisplatin, Cisplatin injection, radical surgery
Tongji Hospital, Southwest Hospital, China, Women Hospital, School of Medicine, Zhejiang University, Anhui Provincial Cancer Hospital, Sichuan Cancer Hospital and Research Institute, Gansu Provincial Maternal and Child Health Care Hospital, Beijing Friendship Hospital, Tianjin Medical University General Hospital, Xiangya Hospital of Central South University, West China Second University Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Zhejiang Cancer Hospital, Shengjing Hospital, Qilu Hospital of Shandong University, Cancer Hospital of Guangxi Medical University
Cervical Cancer, Locally Advanced Cervical Cancer, PD-L1 Negative, Neoadjuvant Chemoimmunotherapy
12/25
12/30
NCT05046314: A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma

Recruiting
2
30
RoW
TK216+Vincristin
Shanghai Pharmaceuticals Holding Co., Ltd
Sarcoma, Ewing
09/25
12/25
ARTEMIS-002, NCT05830123: HS-20093 in Patients With Relapsed or Refractory Osteosarcoma and Other Sarcomas

Recruiting
2
170
RoW
HS-20093
Hansoh BioMedical R&D Company
Osteosarcoma, Sarcoma
12/25
12/27
NCT05761171: A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Recruiting
2
78
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Calaspargase Pegol, Asparaginase (Escherichia coli Isoenzyme II), Conjugate with alpha-(((2,5-Dioxo-1-pyrrolidinyl)oxy)carbonyl)-omega-methoxypoly(oxy-1,2-ethanediyl), Asparlas, Calaspargase Pegol-mknl, EZN-2285, SC-PEG E. Coli L-Asparaginase, Succinimidyl Carbonate Monomethoxypolyethylene Glycol E. coli L-Asparaginase, Cytarabine, .beta.-Cytosine arabinoside, 1-.beta.-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-.beta.-D-Arabinofuranosylcytosine, 1-Beta-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone, 1-Beta-D-arabinofuranosylcytosine, 1.beta.-D-Arabinofuranosylcytosine, 2(1H)-Pyrimidinone, 4-Amino-1-beta-D-arabinofuranosyl-, 2(1H)-Pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl-, Alexan, Ara-C, ARA-cell, Arabine, Arabinofuranosylcytosine, Arabinosylcytosine, Aracytidine, Aracytin, Aracytine, Beta-Cytosine Arabinoside, CHX-3311, Cytarabinum, Cytarbel, Cytosar, Cytosine Arabinoside, Cytosine-.beta.-arabinoside, Cytosine-beta-arabinoside, Erpalfa, Starasid, Tarabine PFS, U 19920, U-19920, Udicil, WR-28453, Echocardiography, EC, Fludarabine Phosphate, 2-F-ara-AMP, 9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-, Beneflur, Fludara, SH T 586, Hydrocortisone Sodium Succinate, (11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt, A-Hydrocort, Buccalsone, Corlan, Cortisol Sodium Succinate, Cortop, Efcortelan, Emergent-EZ, Flebocortid, Hidroc Clora, Hycorace, Hydro-Adreson, Hydrocort, Hydrocortisone 21-Sodium Succinate, Hydrocortisone Na Succinate, Kinogen, Nordicort, Nositrol, Sinsurrene, Sodium hydrocortisone succinate, Solu-Cortef, Solu-Glyc, Lumbar Puncture, LP, Spinal Tap, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Prednisolone, (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, .delta.1-Hydrocortisone, Adnisolone, Aprednislon, Capsoid, Cortalone, Cortisolone, Dacortin H, Decaprednil, Decortin H, Delta(1)Hydrocortisone, Delta- Cortef, Delta-Cortef, Delta-Diona, Delta-F, Delta-Phoricol, Delta1-dehydro-hydrocortisone, Deltacortril, Deltahydrocortisone, Deltasolone, Deltidrosol, Dhasolone, Di-Adreson-F, Dontisolon D, Estilsona, Fisopred, Frisolona, Gupisone, Hostacortin H, Hydeltra, Hydeltrasol, Klismacort, Kuhlprednon, Lenisolone, Lepi-Cortinolo, Linola-H N, Linola-H-Fett N, Longiprednil, Metacortandralone, Meti Derm, Meticortelone, Opredsone, Panafcortelone, Precortisyl, Pred-Clysma, Predeltilone, Predni-Coelin, Predni-Helvacort, Prednicortelone, Prednisolonum, Prelone, Prenilone, Sterane, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Revumenib, Menin-Mixed Lineage Leukemia Protein-Protein Interaction Inhibitor SNDX-5613, Menin-MLL Inhibitor SNDX-5613, Menin-MLL Interaction Inhibitor SNDX-5613, SNDX 5613, SNDX-5613, SNDX5613, Vincristine Sulfate, Kyocristine, Leurocristine Sulfate, Leurocristine, sulfate, Oncovin, Vincasar, Vincosid, Vincrex, Vincristine, sulfate
Children's Oncology Group
Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Refractory Mixed Phenotype Acute Leukemia
12/27
12/27
NCT04203316: Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation

Recruiting
2
10
Canada, US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Enasidenib, AG 221, AG-221, AG221, CC-90007 Free Base, Enasidenib Mesylate, 2-Methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol Methanesulfonate, 2-Propanol, 2-Methyl-1-((4-(6-(trifluoromethyl)-2-pyridinyl)-6-((2-(trifluoromethyl)-4-pyridinyl)amino)-1,3,5-triazin-2-yl)amino)-, Methanesulfonate (1:1), AG-221 Mesylate, CC 90007, CC-90007, CC90007, Enasidenib Methanesulfonate, Idhifa
Children's Oncology Group, National Cancer Institute (NCI)
Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
12/30
12/30
NCT04390737: Evaluate the Safety and Clinical Activity of HH2853

Recruiting
1/2
254
US, RoW
HH2853 Tablets
Haihe Biopharma Co., Ltd.
FL Lymphoma, Epithelioid Sarcoma, Peripheral T Cell Lymphoma, Advanced Solid Tumor
12/25
12/25
AUGMENT-101, NCT04065399 / 2020-004104-34: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Jan 2024 - Dec 2024: Market entry for acute leukemias
Hourglass Feb 2024 - Mar 2024 : Q1'24 - PDUFA date from FDA for R/R KMT2Ar acute leukemia
Dec 2022 - Dec 2023: Submission in US for relapsed/refractory acute leukemia
Jul 2023 - Sep 2023: Data from AUGMENT-101 trial for r/r AML
Checkmark Updated data from P1 portion of P1/2 AUGMENT-101 trial for AML
More
Recruiting
1/2
413
Europe, Canada, US, RoW
revumenib, SNDX-5613, cobicistat
Syndax Pharmaceuticals, Syndax Pharmaceuticals, Inc
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Mixed Lineage Acute Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia of Ambiguous Lineage
12/27
12/27
NCT05944224: A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.

Recruiting
1/2
63
RoW
SPH4336, Cadonilimab
Shanghai Pharmaceuticals Holding Co., Ltd
Advanced Solid Tumors
05/25
12/25
APAL2020SC, NCT04726241: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Recruiting
1/2
960
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection
LLS PedAL Initiative, LLC, Children's Oncology Group, National Cancer Institute (NCI)
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Juvenile Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome
12/26
12/26
NCT05798546: Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)

Recruiting
1
21
RoW
Neo-T, Neoantigen targeting T cells Suspension for Intravenous Infusion, Cyclophosphamide, CTX, Fludarabine, FDR, Interleukin-2, IL-2
BGI, China, Wuhan Union Hospital, China
Solid Tumor
09/23
09/24
NCT04773951: A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors

Recruiting
1
156
RoW
JS004, a recombinant humanized, IgG4κ monoclonal antibody (mAb) specific to B- and T-lymphocyte attenuator (BTLA); Toripalimab Injection
Shanghai Junshi Bioscience Co., Ltd.
Melanoma, Renal Carcinoma, Urothelial Carcinoma
02/24
08/24
NCT04936178: A Study of NB003 in Patients With Advanced Malignancies

Recruiting
1
258
Europe, US, RoW
NB003 tablets
Ningbo Newbay Technology Development Co., Ltd
Advanced Solid Tumor
07/25
12/25
NCT06775067: Incremental Dialysis Decision Model Based on Expert-Guided Machine Learning

Completed
N/A
175
RoW
Huashan Hospital
End-stage Renal Disease
06/24
06/24
NCT06765811: Rapid Kidney Function Decline in Older Adults

Completed
N/A
1539
RoW
Huashan Hospital
Kidney Function Decline, Glomerular Filtration Rate, Urine Albumin-creatinine Ratio, Healthy Aging, Comorbidity, Chronic Kidney Disease
12/22
12/22
NCT04033627: TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia

Recruiting
N/A
30
RoW
In Vitro T cells depletion using CliniMCAS system
Shanghai Children's Medical Center, Nanfang Hospital of Southern Medical University, Children's Hospital Of Soochow University, Chinese University of Hong Kong, Miltenyi Biomedicine GmbH
Relapsed Pediatric ALL, Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis), Relapsed Pediatric AML
07/22
05/24
NCT05918913: Expanded Access Program for Revumenib

Available
N/A
US
Revumenib, SNDX-5613
Syndax Pharmaceuticals
Relapsed/Refractory Acute Leukemia
 
 
HELP-PPCI, NCT05329155: Early Administration of Heparin at FMC for PPCI of STEMI Patients

Completed
N/A
1144
RoW
Heparin Sodium Injection
Renmin Hospital of Wuhan University, Xiangyang Central Hospital, The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture, Wuhan Central Hospital, People's Hospital of Jingshan, Chibi General Hospital, Xianning Central Hospital, Suizhou Central Hospital, Yichang Central People's Hospital, People's Hospital of Tongcheng, Ezhou Central Hospital, Xiantao First People's Hospital, Songzi People's Hospital, Anlu People's Hospital, Caidian People's Hospital, Jiangxia First People's Hospital, Jingzhou Central Hospital, Hubei Zhongshan Hospital, Guoyao Dongfeng General Hospital, Wuhan Puren Hospital, Shiyan People's Hospital, General Hospital of Yangtze River shipping, Fifth Hospital in Wuhan, CR & WISCO General Hospital, Xishui People's Hospital, Jiangling People's Hospital, Wuhan Third Hospital, Laohekou First Hospital, Huanggang Central Hospital, Wuhan No.1 Hospital, Wuhan Hanyang Hospital, Wuxue First People's Hospital, Tianmen First People's Hospital, Xianning First People's Hospital, Wuhan No.6 Hospital, Wuhan Hospital of Traditional Chinese Medicine
STEMI, Primary PCI
08/23
08/24
NCT06423131: Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

Recruiting
N/A
110
RoW
TCRαβ Depleted haploidentical HCT
Sijia Gu
Graft-Versus-Host Disease, Hematopoietic Stem Cell Transplantation, Child, Only, Haploidentical Hematopoietic Stem Cell Transplantation
03/27
03/28
NCT04433455: Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients

Recruiting
N/A
20
RoW
Huashan Hospital
Hemodialysis, Cognitive Impairment, Cerebrovascular Disorders
05/25
05/25
Scherer, Martin
PICTURE, NCT03315390: PTSD After ICU Survival - Caring for Patients With Traumatic Stress Sequelae Following Intensive Medical Care

Completed
N/A
318
Europe
"Narrative Exposure Therapy"-oriented intervention, improved treatment as usual (iTAU)
Ludwig-Maximilians - University of Munich, German Research Foundation, University of Konstanz
Stress Disorders, Post-Traumatic
08/23
01/24
CLIMATE, NCT05961163: Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study

Terminated
N/A
61
Europe
Universitätsklinikum Hamburg-Eppendorf
Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac, Peripheral Artery Disease, Stroke, Ischemic Attack, Transient, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Pulmonary Disease, Chronic Obstructive, Asthma, Renal Insufficiency, Depressive Disorder, Anxiety Disorders, Schizophrenia, Peripheral Nervous System Diseases
09/23
09/23
Christopeit, Maximilian
NCT03897127: Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy with CPX-351 in Adult Patients with Newly Diagnosed AML and Intermediate- or Adverse Genetics

Recruiting
3
882
Europe
Cytarabine, Daunorubicin, CPX-351
University of Ulm, Jazz Pharmaceuticals
Acute Myeloid Leukemia
06/27
06/27
HOVON 156 AML, NCT04027309 / 2018-000624-33: A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy

Active, not recruiting
3
777
Europe, RoW
Gilteritinib, ASP2215, Midostaurin, Rydapt
Stichting Hemato-Oncologie voor Volwassenen Nederland, Deutsch-Österreichische Studiengruppe Akute Myeloische Leukämie (AMLSG), Astellas Pharma Global Development, Inc.
Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
10/25
06/33
NCT04628026: Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Recruiting
3
650
Europe
Venetoclax, Placebo, Standard chemotherapy, Autologous stem cell transplantation, Allogeneic stem cell transplantation
University of Ulm, Stichting Hemato-Oncologie voor Volwassenen Nederland
Acute Myeloid Leukemia, Myelodysplastic Syndromes
02/25
02/31
LENNON, NCT05384691: Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions

Recruiting
2
213
Europe
Luspatercept Injection, LUS
University of Leipzig, Celgene Corporation
Myelodysplastic Syndromes, Anemia
07/26
07/27
AMLSG BiO, NCT01252485: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - the Biology and Outcome (BiO)-Project

Recruiting
N/A
50000
Europe
University of Ulm
Acute Myeloid Leukemia (AML), MDS/AML
12/44
12/44
Patel, Nirav
ASPIRE, NCT03907046: Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

Recruiting
3
700
US
Apixaban, Eliquis, Aspirin
Yale University, National Institute of Neurological Disorders and Stroke (NINDS)
Intracerebral Hemorrhage, Atrial Fibrillation
04/27
04/27
PACES, NCT04045665 / 2021-005022-18: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Recruiting
3
3200
Europe, Canada, US
Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center
Atrial Fibrillation, Stroke, Bleeding
08/26
08/26
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Recruiting
3
1683
US
Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management
University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca
Intracranial Arteriosclerosis, Stroke
05/28
05/28
NCT04845178: Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults

Completed
2
797
NA
ABP-450, prabotulinumtoxinA, Placebo, 0.9% sodium chloride, saline
AEON Biopharma, Inc., PPD
Migraine
06/24
08/24
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
ICE-AFIB, NCT03732794: AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment

Active, not recruiting
N/A
150
US
AtriCure CryoICE & AtriClip LAA Exclusion
AtriCure, Inc.
Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
06/24
06/26
ROMA, NCT03217006: Randomization of Single vs Multiple Arterial Grafts

Active, not recruiting
N/A
4300
Europe, Canada, Japan, US, RoW
Single arterial graft, Multiple arterial grafting
Weill Medical College of Cornell University, National Heart, Lung, and Blood Institute (NHLBI), Canadian Institutes of Health Research (CIHR)
Coronary Artery Disease, Heart Diseases
06/27
01/30
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds

Recruiting
N/A
450
Europe, Canada, US
Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER
Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI)
Mitral Valve Regurgitation
11/28
11/30
NCT04124120: Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
N/A
2000
Europe, Canada, Japan, US, RoW
Single arterial graft, Multiple arterial grafting
Weill Medical College of Cornell University, New York Presbyterian Hospital, Sunnybrook Health Sciences Centre, Cedars-Sinai Medical Center, Columbia University, Duke University
Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
03/30
03/30
Wiegand-Grefe, Silke
Ci-Chimps, NCT05106673: Clinical Implementation and Evaluation for the Family-oriented Care CHIMPS-NET

Recruiting
N/A
798
Europe
Optimal pathways to care, Education and training program for the professionals, Systematic screening, TAU
Universitätsklinikum Hamburg-Eppendorf, Evangelisches Klinikum Bethel, Charite University, Berlin, Germany, Universitätsklinikum Leipzig, University Hospital, Saarland, Immanuel Klinik Rüdersdorf, LWL Klinik Gütersloh, University Hospital, Aachen, University of Ulm, Universitätsklinikum Köln, University Hospital Freiburg, University Hospital Augsburg, University Medical Center Rostock, University Hospital Tuebingen, Helios Kliniken Schwerin, University of Magdeburg, Universitätsklinikum Koblenz - Landau, Helios Klinikum Erfurt, Goethe University
Mental Health Issue
05/23
09/23
NCT03333239: Short-term, Long-term and Cost-effectiveness of Treating Depression and Anxiety Disorders in Children and Adolescents

Not yet recruiting
N/A
420
NA
psychodynamic psychotherapy, cognitive behavioral psychotherapy, psychodynamic family intervention
Universitätsklinikum Hamburg-Eppendorf, University of Bremen
Depression, Anxiety
08/23
08/23
CHIMPS-NET, NCT04369625: Children of Mentally Ill Parents-Network -

Recruiting
N/A
858
Europe
CHIMPS-T, CHIMPS-P, CHIMPS-MFT-group, iCHIMPS
Silke Wiegand-Grefe, Prof. Dr., Universitätsklinikum Hamburg-Eppendorf, Charite University, Berlin, Germany, University Medical Center Rostock, Immanuel Klinik Rüdersdorf, Evangelisches Klinikum Bethel, Universitätsklinikum Köln, University of Göttingen, Ruhr University of Bochum, University Hospital Tuebingen, University Hospital Freiburg, Josefinum Augsburg, University Hospital Augsburg, Klinikum der Universität München, University Hospital, Saarland, University of Magdeburg, Helios Kliniken Schwerin, Universitätsklinikum Marburg, Universitätsklinikum Koblenz - Landau, Pfalzklinikum, Helios Klinikum Erfurt, Bezirkskrankenhaus Günzburg, DAK-Gesundheit Krankenkasse, Techniker Krankenkasse, BARMER, BKK Mobil Oil, KKH Kaufmännische Krankenkasse, IKK Classic Krankenkasse, AOK Hessen, University of Ulm, University Hospital Heidelberg, aQua-Institut, Leibniz Universität, Center for Health Economics Research Hannover, AFET Bundesverband für Erziehungshilfe e.V., Dachverband Gemeindepsychiatrie, AOK Baden-Württemberg, LWL Klinik Gütersloh, Staedtisches Klinikum Karlsruhe
Mental Health Issue
11/23
12/23
Gebhardt, Christoffer
NCT05529316: A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma

Active, not recruiting
2
220
Europe, US, RoW
Botensilimab, AGEN1181, Balstilimab, AGEN2034
Agenus Inc.
Advanced Melanoma
05/28
05/28
NCT03683550: Comparing SLNE With or Without Preoperative Hybrid SPECT/CT in Melanoma

Active, not recruiting
N/A
836
Europe
SLNE with preoperative hybrid SPECT/CT, Standard SLNE
University Hospital, Essen
Melanoma
06/25
06/25
Bley, Annette
CANinform, NCT04126005: Natural History Study of Patients With Canavan Disease ( Study)

Recruiting
N/A
70
Europe, US
Aspa Therapeutics
Canavan Disease
12/25
04/26
Nierhaus, Axel
ARISS, NCT03869385: Albumin Replacement Therapy in Septic Shock

Terminated
3
440
Europe
Albutein® 200 g/L or Plasbumin® 20, Human Albumin 20%
Jena University Hospital, German Research Foundation, Instituto Grifols, S.A., University Hospital Goettingen, SepNet - Critical Care Trials Group, Center for Sepsis Control and Care, Germany
Septic Shock
07/22
06/23
EPOS-1, NCT05033808: Epirubicin for the Treatment of Sepsis & Septic Shock

Recruiting
2
45
Europe
Epirubicin, Placebo
Jena University Hospital, Ruhr University of Bochum, University Medicine Greifswald
Sepsis
10/24
12/24
PEPPER, NCT03334006 / 2016-001788-34: Prospective, Randomized Trial of Personalized Medicine with Pentaglobin® After Surgical Infectious Source Control in Patients with Peritonitis

Recruiting
2
200
Europe
Pentaglobin®/Standard of Care
RWTH Aachen University, Biotest
Peritonitis, Sepsis, Septic Shock
09/27
03/28
 

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