Gagnadoux, Frédéric |
| Recruiting | 4 | 378 | Europe | pirfenidone and nintedanib, pirfenidone or nintedanib | Hospices Civils de Lyon, Ministry of Health | Progressive Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
| Recruiting | 3 | 86 | Europe | bosentan, placebo | University Hospital, Grenoble | Ischemic Optic Neuropathy | 12/23 | 12/25 | | |
BEconneCTD-ILD, NCT06572384: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease |
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| Recruiting | 3 | 440 | Europe, Japan, US, RoW | Belimumab, BENLYSTA, GSK1550188, Placebo | GlaxoSmithKline | Lung Diseases, Interstitial | 10/28 | 12/28 | | |
AKAPI, NCT06585020: Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection |
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| Not yet recruiting | 2 | 190 | Europe | Arikayce, standard treatment | Centre Hospitalier Universitaire, Amiens, University Hospital, Angers, Hospital Avicenne, University Hospital, Bordeaux, University Hospital, Brest, CH Compiègne, Créteil Hospital, Centre Hospitalier Universitaire Dijon, University Hospital, Grenoble, Centre Hospitalier le Mans, Hôpital de la Croix-Rousse, APHM - Nord, Hôpital Saint Joseph, CH Mulhouse, CH Orléans, Tenon Hospital, Paris, Hôpital Necker-Enfants Malades, CH PERPIGNAN, Poitiers University Hospital, CH Pontoise, CHU de Reims, Rennes University Hospital, CHU de Rouen - Accueil, Central Hospital Saint Quentin, IHU Strasbourg, University Hospital, Tours, CH Abbeville, CH Cannes | Mycobacterium; Xenopi, Lung Diseases | 08/26 | 08/27 | | |
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): |
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| Terminated | N/A | 41 | Europe | CPAP associated with connected devices: blood pressure monitor , scales and activity monitor | University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France) | Obstructive Sleep Apnea Syndrome | 01/24 | 02/24 | | |
EXODYS, NCT04459182: Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome |
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| Completed | N/A | 99 | Europe | ENDOPAT | University Hospital, Angers | Endothelial Dysfunction | 07/23 | 07/23 | | |
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis |
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| Completed | N/A | 848 | Europe | Sunrise, polysomnography | Sunrise, ICUREsearch | Obstructive Sleep Apnea | 10/24 | 10/24 | | |
NCT02346305: Cohort of Respiratory Failure Patients Treated for the First Time With Non-Invasive Ventilation at Home |
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| Recruiting | N/A | 3000 | Europe | Non-invasive ventilation | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | Respiratory Insufficiency | 12/24 | 12/24 | | |
RAMBO, NCT05015153: Impact on Quality of Life with Pulmonary RehAbilitation After Pulmonary EMBOlism: Study |
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| Recruiting | N/A | 112 | Europe | Pulmonary rehabilitation (PR) | University Hospital, Brest | Pulmonary Embolism, Quality of Life and Dyspnea | 12/26 | 02/28 | | |
PANTHERA, NCT05461417: Long-term Efficacy, Tolerance and Compliance of Panthera D-SAD® Mandibular Advancement Orthosis in Sleep Apnea |
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| Active, not recruiting | N/A | 337 | Europe | D-SAD | Panthera Dental Inc., AXONAL | Sleep Apnea, Obstructive | 05/29 | 05/29 | | |
| Recruiting | N/A | 400 | Europe | CPAP, MAD | ResMed | OSA | 10/22 | 10/26 | | |
Pépin, Jean-Louis JP |
keePaOSA, NCT04875897: Efficacy and Safety of keepMED Positive Airway Pressure Device in Patients With Obstructive Sleep Apnea |
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| Not yet recruiting | N/A | 65 | NA | keepMED PAP device | keepMED Ltd., CRI-The Clinical Research Institute GmbH | Obstructive Sleep Apnea | 01/22 | 02/22 | | |
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): |
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| Terminated | N/A | 41 | Europe | CPAP associated with connected devices: blood pressure monitor , scales and activity monitor | University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France) | Obstructive Sleep Apnea Syndrome | 01/24 | 02/24 | | |
PWV follow-up, NCT04704401: Long-Term Follow-up in Patients Included in the Meta-analysis "Sleep Apnea Syndrome and Arterial Stiffness" |
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| Recruiting | N/A | 893 | Europe | Questionnaire | University Hospital, Grenoble | Sleep Apnea | 10/25 | 10/25 | | |
| Recruiting | N/A | 500 | Europe | Questionnaire | University Hospital, Grenoble | Sleep Apnea | 11/25 | 11/25 | | |
NCT05698602: Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at Home |
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| Active, not recruiting | N/A | 10 | Europe | NivolisMonitor, NivolisAnton | VIVARDIS | Respiratory Insufficiency, Respiratory Failure, Home Monitoring | 07/25 | 12/25 | | |
| Recruiting | N/A | 500 | Europe | | University Hospital, Grenoble, Act For Chronic Diseases, HP2 laboratory INSERM U1042, University Grenoble Alps | Obesity, Obstructive Sleep Apnea, Sleep | 01/24 | 01/24 | | |
| Not yet recruiting | N/A | 176 | Europe | PWV measurement | Withings | Vascular Stiffness | 05/24 | 11/24 | | |
| Recruiting | N/A | 1600 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Cardiomyopathy, Diabetic | 10/27 | 10/27 | | |
| Recruiting | N/A | 1620 | Europe | Treatment according to standard care recommandation | University Hospital, Grenoble | Stroke, Sleep-disordered Breathing, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Sleep Apnea, Central, Fragmentation, Sleep | 06/30 | 06/35 | | |
| Not yet recruiting | N/A | 10000 | NA | Nutritional Psycho-Behavioral Reeducation Program, RNPC Program | Groupe Éthique et Santé, University Grenoble Alps, Novo Nordisk A/S, Lyon Est University | Overweight and Obesity, Cardiovascular Diseases, Metabolic Disease, Diabete Type 2, Sleep Apnea, Obstructive, NAFLD, NASH | 07/30 | 07/30 | | |
Kahane, Philippe PK |
SPREAD, NCT03321240: Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia |
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| Recruiting | N/A | 240 | Europe | visual and quantitative SEEG signal analysis, Resective epilepsy surgery procedure | University Hospital, Strasbourg, France | Refractory Epilepsy, Focal Epilepsy, Focal Cortical Dysplasia | 12/22 | 12/22 | | |
| Enrolling by invitation | N/A | 400 | Europe, Canada, Japan, US, RoW | Stereoelectroencephalography (SEEG) | Duke University, Christian Doppler University Hospital | Epilepsy Intractable | 11/25 | 11/25 | | |
| Recruiting | N/A | 140 | Europe | Choice of VNS set of parameters based on the lowest PLI, EEG | Assistance Publique Hopitaux De Marseille | Epilepsy | 06/25 | 12/26 | | |
| Recruiting | N/A | 200 | Europe | SEEG Group | University Hospital, Grenoble | Refractory Epilepsy, Focal Epilepsy | 03/28 | 09/30 | | |
| Not yet recruiting | N/A | 40 | NA | mqMRI and GABA-MRS | University Hospital, Grenoble, Université Grenoble-Alpes, Institut National de la Santé Et de la Recherche Médicale, France | Epilepsy, Temporal Lobe | 11/28 | 11/28 | | |
| Recruiting | N/A | 400 | Europe | Cognitive tasks | University Hospital, Grenoble, Grenoble Institut des Neurosciences | Focal Brain Injury, Cognition | 02/30 | 02/30 | | |
Mousseau, Mireille |
Decrescendo, NCT04675827: De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade |
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| Terminated | 2 | 139 | Europe, RoW | Pertuzumab and tratuzumab fixed dose combination, Adjuvant pertuzumab + trastuzumab FDC SC for 14 cycles, Fixed-dose combination of Perjeta and Herceptin for subcutaneous injection for 14 cycles, Trastuzumab emtansine, Adjuvant T-DM1 | Jules Bordet Institute, Breast International Group, Hoffmann-La Roche, International Drug Development Institute, Institut Curie | HER2-positive Breast Cancer, ER-Negative Breast Cancer, PR-Negative Breast Cancer, Node-negative Breast Cancer | 11/24 | 11/24 | | |
NCT05388734: Shared Decision Making on Care Pathways and CAMs: A Pilot Study |
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| Recruiting | N/A | 100 | Europe | alternative medicine education consultation | University Hospital, Grenoble, University Grenoble Alps, Laboratoire TIMC-IMAG | Breast Cancer, Non-metastatic, Newly Diagnosed, Feasibility Study | 01/24 | 08/24 | | |
| Recruiting | N/A | 1500 | Europe | Conventional treatment protocols of breast cancer | University Hospital, Grenoble | Breast Cancer | 12/33 | 12/33 | | |
Tamisier, Renaud |
| Recruiting | 3 | 86 | Europe | bosentan, placebo | University Hospital, Grenoble | Ischemic Optic Neuropathy | 12/23 | 12/25 | | |
PLASTIHC, NCT05210088: PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke |
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| Withdrawn | 1/2 | 40 | Europe | Hypoxia, intermittent, Hypoxic conditioning, Hypoxia, Normoxia | University Hospital, Grenoble, Agir pour les maladies chroniques | Stroke, Ischemic, Stroke Sequelae | 01/24 | 01/24 | | |
| Active, not recruiting | N/A | 395 | Europe | No intervention | University Hospital, Grenoble | COVID-19 | 03/22 | 06/26 | | |
| Completed | N/A | 7 | Europe | Activated Inspire® Upper Airway Stimulation System, Inactivated Inspire® Upper Airway Stimulation System | University Hospital, Grenoble, Inspire Medical Systems, Inc. | Obstructive Sleep Apnea Syndrome | 12/21 | 10/23 | | |
STIMOBIII, NCT02210585: Study of Neuromuscular Electrical Stimulation to Increase Spontaneous Physical Activity in Obesity Patient |
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| Completed | N/A | 73 | Europe | Rehabilitation | University Hospital, Grenoble | Obesity, Number of Steps Per Day < 7000 | 05/24 | 05/24 | | |
| Recruiting | N/A | 62 | Europe | Physical activity intervention | University Hospital, Grenoble, HP2 Laboratory | Obstructive Sleep Apnea | 10/26 | 10/26 | | |
| Terminated | N/A | 65 | Europe | Questionnaires, blood test, Maximal effort test, actigraphy, Neuromuscular evaluation, stool analysis, food diary | Centre Hospitalier Universitaire de Saint Etienne, University of Saint-Etienne, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Chronic Fatigue Syndrome, Intensive Care Unit, Muscle | 07/21 | 08/21 | | |
PWV follow-up, NCT04704401: Long-Term Follow-up in Patients Included in the Meta-analysis "Sleep Apnea Syndrome and Arterial Stiffness" |
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| Recruiting | N/A | 893 | Europe | Questionnaire | University Hospital, Grenoble | Sleep Apnea | 10/25 | 10/25 | | |
| Recruiting | N/A | 500 | Europe | Questionnaire | University Hospital, Grenoble | Sleep Apnea | 11/25 | 11/25 | | |
| Recruiting | N/A | 500 | Europe | | University Hospital, Grenoble, Act For Chronic Diseases, HP2 laboratory INSERM U1042, University Grenoble Alps | Obesity, Obstructive Sleep Apnea, Sleep | 01/24 | 01/24 | | |
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis |
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| Completed | N/A | 848 | Europe | Sunrise, polysomnography | Sunrise, ICUREsearch | Obstructive Sleep Apnea | 10/24 | 10/24 | | |
| Recruiting | N/A | 70 | Europe | Deem 3 Headband | University Hospital, Grenoble, Dreem, AGIR à Dom | Sleep Apnea, Obstructive Sleep Apnea | 11/25 | 12/25 | | |
| Recruiting | N/A | 250 | Europe | Videoconsultation | University Hospital, Grenoble, University Hospital, Angers | Obstructive Sleep Apnea | 03/26 | 03/26 | | |
| Recruiting | N/A | 150 | Europe | | University Hospital, Grenoble | Chronic Obstructive Pulmonary Disease | 11/29 | 12/29 | | |
| Recruiting | N/A | 1620 | Europe | Treatment according to standard care recommandation | University Hospital, Grenoble | Stroke, Sleep-disordered Breathing, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Sleep Apnea, Central, Fragmentation, Sleep | 06/30 | 06/35 | | |
| Recruiting | N/A | 300 | Europe | SFRMS/SPLF CPAP-telemonitoring diagnosis/therapeutic algorithm. | University Hospital, Montpellier, ADENE, Montpellier, AGIR à dom, Meylan, ASTEN sante, Pays de la Loire, ELIA medical, Cesson-Sévigné | Obstructive Sleep Apnea | 12/21 | 12/23 | | |
| Recruiting | N/A | 400 | Europe | CPAP, MAD | ResMed | OSA | 10/22 | 10/26 | | |
Gentina, Thibaut |
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): |
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| Terminated | N/A | 41 | Europe | CPAP associated with connected devices: blood pressure monitor , scales and activity monitor | University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France) | Obstructive Sleep Apnea Syndrome | 01/24 | 02/24 | | |
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis |
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| Completed | N/A | 848 | Europe | Sunrise, polysomnography | Sunrise, ICUREsearch | Obstructive Sleep Apnea | 10/24 | 10/24 | | |
KRAINIK, Alexandre A |
PLASTIHC, NCT05210088: PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke |
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| Withdrawn | 1/2 | 40 | Europe | Hypoxia, intermittent, Hypoxic conditioning, Hypoxia, Normoxia | University Hospital, Grenoble, Agir pour les maladies chroniques | Stroke, Ischemic, Stroke Sequelae | 01/24 | 01/24 | | |
ALLA, Corinne C ARAMARI |
NEUROBLU 02, NCT03966651 / 2020-002996-36: A Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-DOTA0-Tyr3-Octreotate in Children With Refractory or Recurrent Neuroblastoma Expressing Somatostatin Receptors. |
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| Recruiting | 1 | 18 | Europe | PRRT with 177Lu-DOTATATE | Institut Claudius Regaud, Advanced Accelerator Applications | Neuroblastoma | 10/25 | 02/26 | | |
APADHOP, NCT06230016: Adhesion of Children and Adolescents Treated for Cancer to Personalized Support in Adapted Physical Activity Program |
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| Recruiting | N/A | 48 | Europe | questionnaires, PedsQL quality of life questionnaires | University Hospital, Grenoble, University Grenoble Alps | Childhood Cancer, Adapted Physical Activity | 08/25 | 01/26 | | |
| Active, not recruiting | N/A | 2093 | Europe, RoW | Hydroxycarbamide, Siklos, Hydroxyurea | Theravia, International Clinical Trials Association | Sickle Cell Disease | 08/25 | 08/25 | | |
ALARM3, NCT05772559: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies |
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| Recruiting | N/A | 500 | Europe | Collection of blood sample of bone marrow (cohort 1), Collection of blood sample of bone marrow (cohort 2 and 3) | Assistance Publique - Hôpitaux de Paris | Acute Myeloid Leukemia, Genetic Predisposition to Disease | 05/33 | 05/33 | | |
DURAND, CHANTAL C |
ORACLE, NCT05100771: Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy |
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| Recruiting | N/A | 240 | Europe | Pediatric brain MRI | University Hospital, Tours | Focal Epilepsy | 03/25 | 03/25 | | |
Bouzat, Pierre |
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype |
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| Recruiting | 3 | 450 | Europe | Dexamethasone, Placebo | Nantes University Hospital | Hospital Acquired Pneumonia | 03/26 | 08/26 | | |
T-STORHM, NCT04431999: Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage |
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| Recruiting | 3 | 200 | Europe | Whole blood transfusion, Fractionated blood products transfusion | Direction Centrale du Service de Santé des Armées, TIMC-IMAG, Floralis | Trauma, Acute Hemorrhage, Coagulopathy | 09/24 | 09/25 | | |
| Not yet recruiting | 3 | 1218 | Europe | direct IV injection, combination of Ketamine and Propofol | Nantes University Hospital | Rapid Sequence Induction | 03/27 | 04/27 | | |
RADIOMIC-TBI, NCT04058379: Artificial Intelligence Analysis of Initial Scan Evolution of Traumatic Brain Injured Patient to Predict Neurological Outcome |
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| Active, not recruiting | N/A | 30 | Europe | CT scan | University Hospital, Grenoble | Trauma, Brain | 04/21 | 10/21 | | |
ALPACA, NCT06248736: Description of Lactulose Administration by Balloon Rectal Tube in Severe Hepatic Encephalopathy |
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| Completed | N/A | 25 | Europe | | University Hospital, Grenoble | Hepatic Encephalopathy | 08/24 | 08/24 | | |
| Completed | N/A | 1066 | Europe, RoW | Quantification of IV drugs wastage | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer, Sainte-Anne Military Teaching Hospital | Drug Use | 03/23 | 03/23 | | |
| Terminated | N/A | 65 | Europe | Questionnaires, blood test, Maximal effort test, actigraphy, Neuromuscular evaluation, stool analysis, food diary | Centre Hospitalier Universitaire de Saint Etienne, University of Saint-Etienne, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Chronic Fatigue Syndrome, Intensive Care Unit, Muscle | 07/21 | 08/21 | | |
| Recruiting | N/A | 984 | Europe, RoW | Transcranial Doppler (TCD) | University Hospital, Grenoble | Mild Traumatic Brain Injury | 05/25 | 07/26 | | |
OPTI-TWO, NCT05893030: Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk |
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| Recruiting | N/A | 1132 | Europe | anesthesia guided by sedation and analgesia monitoring, anesthesia performed according only to the clinical judgment of the anesthetist as usual practice | Centre Hospitalier Universitaire de Saint Etienne, Direction Générale de l'Offre de Soins | Sedation and Analgesia Monitoring | 01/27 | 12/27 | | |
JAFFUEL, Dany |
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): |
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| Terminated | N/A | 41 | Europe | CPAP associated with connected devices: blood pressure monitor , scales and activity monitor | University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France) | Obstructive Sleep Apnea Syndrome | 01/24 | 02/24 | | |
| Completed | N/A | 55 | Europe | Measure of mandibular movement using a mid-sagittal magnetic sensor (Brizzy, Jawac©) Nomics, Liege, Belgium), Gold standard: polysomnography | University Hospital, Montpellier, ADENE | Rhinitis | 06/24 | 11/24 | | |
| Recruiting | N/A | 300 | Europe | SFRMS/SPLF CPAP-telemonitoring diagnosis/therapeutic algorithm. | University Hospital, Montpellier, ADENE, Montpellier, AGIR à dom, Meylan, ASTEN sante, Pays de la Loire, ELIA medical, Cesson-Sévigné | Obstructive Sleep Apnea | 12/21 | 12/23 | | |
Plantaz, Dominique |
CAALL-F01, NCT02716233: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents |
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| Recruiting | 3 | 1578 | Europe | pegaspargase 1250 IU/m2 x 2, ONCASPAR 1250 IU/m2 x 2, pegaspargase 2500 IU/m2 x 1, ONCASPAR 2500 IU/m2 x 1 | Assistance Publique - Hôpitaux de Paris, Shire | Acute Lymphoblastic Leukemia | 04/26 | 04/26 | | |
| Recruiting | 3 | 800 | Europe, RoW | Vincristine, L01CA02, Carboplatin, LO1XA02, Etoposide, L01CB01, Vindesine, L01CA03, Dacarbazine, L01AX04, Ifosfamide, Doxorubicin, L01DB01, Busulfan, L01AB01, Melphalan, L01AA03, Thiotepa, L01AC01, Radiotherapy, Dinutuximab Beta, L01XC16, Cisplatin, L01XA01, Temozolomide 100 MG, Irinotecan, Cyclophosphamid | Gustave Roussy, Cancer Campus, Grand Paris, PHRC, Solving Kids' Cancer Europe, Neuroblastoma UK, , BSPHO, Instituto de Investigación Sanitaria La Fe, Deutsche Krebshilfe | High-Risk Neuroblastoma, Patient With Insufficient Response Chemoimmunotherapy | 11/26 | 11/32 | | |
| Recruiting | 2/3 | 1800 | Europe, Canada, RoW | VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin | St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group | Acute Lymphoblastic Leukaemia | 06/25 | 04/30 | | |
| Recruiting | 2/3 | 225 | Europe | Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma | 01/35 | 01/36 | | |
| Active, not recruiting | 2 | 133 | Europe | VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma, Children, Retinal Neoplasm | 01/23 | 09/35 | | |
| Recruiting | 2 | 185 | Europe | Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation | Institut Curie | Retinoblastoma | 03/30 | 09/30 | | |
| Recruiting | 1/2 | 28 | Europe | Vincristine, Irinotecan, Temozolomide, Etoposide, Cis-Retinoic acid | Centre Oscar Lambret | Wilms Tumor | 05/28 | 10/28 | | |
CURALASE01, NCT04596410: Photobiomodulation Protocols in the Analgesia of Chemotherapy-induced Oral Mucositis in Children |
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| Recruiting | N/A | 406 | Europe | LLLT applied every other day, LLLT applied daily | University Hospital, Toulouse | Mucositis Oral | 01/24 | 02/24 | | |
| Recruiting | N/A | 300 | Europe, RoW | Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available | University Hospital, Angers | Predisposition, Genetic, Cancer Childhood, Development Delay | 02/25 | 08/25 | | |
SACHA, NCT04477681: Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults |
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| Recruiting | N/A | 1000 | Europe | Data collection | Gustave Roussy, Cancer Campus, Grand Paris, Société Française des Cancers de l'Enfant (SFCE) | Pediatric Cancer | 04/26 | 04/27 | | |
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults |
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| Active, not recruiting | N/A | 600 | Europe | Sampling on blood, bone marrow and cerebrospinal fluid | Institut Curie | Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor | 04/27 | 08/27 | | |
Minotti, Lorella |
REPREO, NCT05609084: Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy |
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| Recruiting | N/A | 214 | Europe | Speech therapy, Speech therapy assessment | Assistance Publique Hopitaux De Marseille | Epilepsy, Anomia, Temporal Lobe Epilepsy | 03/27 | 11/27 | | |
Llerena, Catherine |
Lum-Iva-Biota, NCT03565692: Lum-Iva-biota: Exploring the Respiratory Mycobiota and Microbiota Profile in French CF Patients Taking Lumacaftor-Ivacaftor |
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| Recruiting | N/A | 250 | Europe | the lung mycobiota and microbiota profile, the gut mycobiota and microbiota profile | University Hospital, Bordeaux, Societe Francaise de la Mucoviscidose | Cystic Fibrosis | 02/23 | 02/23 | | |
KAF-BIOTA, NCT05937815: Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor |
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| Recruiting | N/A | 253 | Europe | Sample collection | University Hospital, Bordeaux | Cystic Fibrosis | 09/23 | 09/24 | | |
| Active, not recruiting | N/A | 331 | Europe | Blood sample | Hospices Civils de Lyon, Queen's University, Belfast | COVID-19, Cystic Fibrosis | 06/25 | 06/25 | | |
MUKADO, NCT05795673: Peer-supporting for Teenagers With Cystic Fibrosis in the Transition of Care From Paediatric to Adult Services |
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| Not yet recruiting | N/A | 88 | Europe | Peer support program (intervention phase) | Hospices Civils de Lyon | Cystic Fibrosis | 09/26 | 09/26 | | |
SCHIFF, Isabelle I |
APADHOP, NCT06230016: Adhesion of Children and Adolescents Treated for Cancer to Personalized Support in Adapted Physical Activity Program |
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| Recruiting | N/A | 48 | Europe | questionnaires, PedsQL quality of life questionnaires | University Hospital, Grenoble, University Grenoble Alps | Childhood Cancer, Adapted Physical Activity | 08/25 | 01/26 | | |
TOFFART, Anne-Claire |
| Active, not recruiting | 2 | 55 | Europe | Nivolumab, BMS-936558-01 | European Organisation for Research and Treatment of Cancer - EORTC, ETOP IBCSG Partners Foundation | Thymoma Type B3, Thymic Carcinoma | 12/23 | 07/24 | | |
METABO-ICI, NCT04189679: Identification of a Predictive Metabolic Signature of Response to Immune Checkpoint Inhibitors in Non-Small Cell Lung Carcinoma |
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| Completed | N/A | 62 | Europe | Immune signature in serum associated to the metabolic signature, Meta-genomic signature of intestinal flora | University Hospital, Grenoble | Non Small Cell Lung Cancer | 01/23 | 01/23 | | |
PACT-01, NCT04823377: Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer. |
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| Recruiting | N/A | 364 | Europe | Usual care, Optimization of the medical decision | Institut Curie | Carcinoma, Non-Small-Cell Lung, Advanced Cancer | 09/26 | 09/27 | | |
| Recruiting | N/A | 4975 | Europe, RoW | RP-1828 IMMUcan, RP-1759 AYA/TYA, RP-1843 Arcagen, RP-1920 BioRadon | European Organisation for Research and Treatment of Cancer - EORTC | All Tumor Types | 03/26 | 03/26 | | |
PRIMALung, NCT04790253: PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients ( Study) |
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| Recruiting | N/A | 600 | Europe | Prophylactic cranial irradiation | European Organisation for Research and Treatment of Cancer - EORTC, UNICANCER | Limited Stage Small Cell Lung Cancer, Extensive-stage Small-cell Lung Cancer | 04/28 | 04/28 | | |
ROSIE, NCT06053099: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19) |
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| Recruiting | N/A | 300 | Europe | Plasma ctDNA, FFPE blocks | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer, EGFR Activating Mutation, EGFR DEL19, EGFR L858R | 10/31 | 10/31 | | |
MOUSSSEAU, Mireille |
| Recruiting | N/A | 1500 | Europe | Conventional treatment protocols of breast cancer | University Hospital, Grenoble | Breast Cancer | 12/33 | 12/33 | | |