UniversityHospitalGrenoble
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 69 Trials 
91 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Gagnadoux, Frédéric
NCT03939520 / 2019-004326-19: Management of Progressive Disease in Idiopathic Pulmonary Fibrosis

Recruiting
4
378
Europe
pirfenidone and nintedanib, pirfenidone or nintedanib
Hospices Civils de Lyon, Ministry of Health
Progressive Idiopathic Pulmonary Fibrosis
01/26
01/26
ENDOTHELION, NCT02377271 / 2014-000848-14: Study Group: Effect of Bosentan in NAION Patients

Recruiting
3
86
Europe
bosentan, placebo
University Hospital, Grenoble
Ischemic Optic Neuropathy
12/23
12/25
BEconneCTD-ILD, NCT06572384: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

Recruiting
3
440
Europe, Japan, US, RoW
Belimumab, BENLYSTA, GSK1550188, Placebo
GlaxoSmithKline
Lung Diseases, Interstitial
10/28
12/28
AKAPI, NCT06585020: Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection

Not yet recruiting
2
190
Europe
Arikayce, standard treatment
Centre Hospitalier Universitaire, Amiens, University Hospital, Angers, Hospital Avicenne, University Hospital, Bordeaux, University Hospital, Brest, CH Compiègne, Créteil Hospital, Centre Hospitalier Universitaire Dijon, University Hospital, Grenoble, Centre Hospitalier le Mans, Hôpital de la Croix-Rousse, APHM - Nord, Hôpital Saint Joseph, CH Mulhouse, CH Orléans, Tenon Hospital, Paris, Hôpital Necker-Enfants Malades, CH PERPIGNAN, Poitiers University Hospital, CH Pontoise, CHU de Reims, Rennes University Hospital, CHU de Rouen - Accueil, Central Hospital Saint Quentin, IHU Strasbourg, University Hospital, Tours, CH Abbeville, CH Cannes
Mycobacterium; Xenopi, Lung Diseases
08/26
08/27
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP):

Terminated
N/A
41
Europe
CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France)
Obstructive Sleep Apnea Syndrome
01/24
02/24
EXODYS, NCT04459182: Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome

Completed
N/A
99
Europe
ENDOPAT
University Hospital, Angers
Endothelial Dysfunction
07/23
07/23
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis

Completed
N/A
848
Europe
Sunrise, polysomnography
Sunrise, ICUREsearch
Obstructive Sleep Apnea
10/24
10/24
NCT02346305: Cohort of Respiratory Failure Patients Treated for the First Time With Non-Invasive Ventilation at Home

Recruiting
N/A
3000
Europe
Non-invasive ventilation
Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Respiratory Insufficiency
12/24
12/24
RAMBO, NCT05015153: Impact on Quality of Life with Pulmonary RehAbilitation After Pulmonary EMBOlism: Study

Recruiting
N/A
112
Europe
Pulmonary rehabilitation (PR)
University Hospital, Brest
Pulmonary Embolism, Quality of Life and Dyspnea
12/26
02/28
PANTHERA, NCT05461417: Long-term Efficacy, Tolerance and Compliance of Panthera D-SAD® Mandibular Advancement Orthosis in Sleep Apnea

Active, not recruiting
N/A
337
Europe
D-SAD
Panthera Dental Inc., AXONAL
Sleep Apnea, Obstructive
05/29
05/29
REMAP, NCT05435794: Long-term Benefits of CPAP or MAD Treatment on the Sleep of OSAS Patients

Recruiting
N/A
400
Europe
CPAP, MAD
ResMed
OSA
10/22
10/26
Pépin, Jean-Louis JP
keePaOSA, NCT04875897: Efficacy and Safety of keepMED Positive Airway Pressure Device in Patients With Obstructive Sleep Apnea

Not yet recruiting
N/A
65
NA
keepMED PAP device
keepMED Ltd., CRI-The Clinical Research Institute GmbH
Obstructive Sleep Apnea
01/22
02/22
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP):

Terminated
N/A
41
Europe
CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France)
Obstructive Sleep Apnea Syndrome
01/24
02/24
PWV follow-up, NCT04704401: Long-Term Follow-up in Patients Included in the Meta-analysis "Sleep Apnea Syndrome and Arterial Stiffness"

Recruiting
N/A
893
Europe
Questionnaire
University Hospital, Grenoble
Sleep Apnea
10/25
10/25
ESADAfollow-up, NCT04800341: Long-term Follow-up in Patients Included in the European Sleep Apnea Data Base (ESADA)

Recruiting
N/A
500
Europe
Questionnaire
University Hospital, Grenoble
Sleep Apnea
11/25
11/25
NCT05698602: Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at Home

Active, not recruiting
N/A
10
Europe
NivolisMonitor, NivolisAnton
VIVARDIS
Respiratory Insufficiency, Respiratory Failure, Home Monitoring
07/25
12/25
NCT02264431: Severe Obesity Outcome Network Cohort (SOON)

Recruiting
N/A
500
Europe
University Hospital, Grenoble, Act For Chronic Diseases, HP2 laboratory INSERM U1042, University Grenoble Alps
Obesity, Obstructive Sleep Apnea, Sleep
01/24
01/24
WIVOP-Scales, NCT05823025: Withings Study to Analyze the Accuracy of Pulse Wave Velocity Measurement With Bathroom Scales

Not yet recruiting
N/A
176
Europe
PWV measurement
Withings
Vascular Stiffness
05/24
11/24
CARDIATEAM, NCT04303364: CARdiomyopathy in Type 2 DIAbetes Mellitus

Recruiting
N/A
1600
Europe
Institut National de la Santé Et de la Recherche Médicale, France
Cardiomyopathy, Diabetic
10/27
10/27
ASCENT, NCT04399200: Apnea, Stroke and Incident Cardiovascular Events

Recruiting
N/A
1620
Europe
Treatment according to standard care recommandation
University Hospital, Grenoble
Stroke, Sleep-disordered Breathing, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Sleep Apnea, Central, Fragmentation, Sleep
06/30
06/35
SCOOP-RNPC, NCT05857319: Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients

Not yet recruiting
N/A
10000
NA
Nutritional Psycho-Behavioral Reeducation Program, RNPC Program
Groupe Éthique et Santé, University Grenoble Alps, Novo Nordisk A/S, Lyon Est University
Overweight and Obesity, Cardiovascular Diseases, Metabolic Disease, Diabete Type 2, Sleep Apnea, Obstructive, NAFLD, NASH
07/30
07/30
Kahane, Philippe PK
SPREAD, NCT03321240: Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia

Recruiting
N/A
240
Europe
visual and quantitative SEEG signal analysis, Resective epilepsy surgery procedure
University Hospital, Strasbourg, France
Refractory Epilepsy, Focal Epilepsy, Focal Cortical Dysplasia
12/22
12/22
NCT06138808: 5-SENSE Score Validation Study

Enrolling by invitation
N/A
400
Europe, Canada, Japan, US, RoW
Stereoelectroencephalography (SEEG)
Duke University, Christian Doppler University Hospital
Epilepsy Intractable
11/25
11/25
OPSTIMVAG, NCT04693221: Optimization of the Parameters of Vagal Nerve Stimulation

Recruiting
N/A
140
Europe
Choice of VNS set of parameters based on the lowest PLI, EEG
Assistance Publique Hopitaux De Marseille
Epilepsy
06/25
12/26
MAPCOG-SEEG, NCT03644732: Atlas of Human Cognition by SEEG

Recruiting
N/A
200
Europe
SEEG Group
University Hospital, Grenoble
Refractory Epilepsy, Focal Epilepsy
03/28
09/30
EPI-CATCHER, NCT06057233: Innovative MRI to Localize the Epileptic Zone

Not yet recruiting
N/A
40
NA
mqMRI and GABA-MRS
University Hospital, Grenoble, Université Grenoble-Alpes, Institut National de la Santé Et de la Recherche Médicale, France
Epilepsy, Temporal Lobe
11/28
11/28
LESCOG, NCT04182087: Cognitive Function Assessment in Patients With Focal Brain Injury

Recruiting
N/A
400
Europe
Cognitive tasks
University Hospital, Grenoble, Grenoble Institut des Neurosciences
Focal Brain Injury, Cognition
02/30
02/30
Mousseau, Mireille
Decrescendo, NCT04675827: De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade

Terminated
2
139
Europe, RoW
Pertuzumab and tratuzumab fixed dose combination, Adjuvant pertuzumab + trastuzumab FDC SC for 14 cycles, Fixed-dose combination of Perjeta and Herceptin for subcutaneous injection for 14 cycles, Trastuzumab emtansine, Adjuvant T-DM1
Jules Bordet Institute, Breast International Group, Hoffmann-La Roche, International Drug Development Institute, Institut Curie
HER2-positive Breast Cancer, ER-Negative Breast Cancer, PR-Negative Breast Cancer, Node-negative Breast Cancer
11/24
11/24
NCT05388734: Shared Decision Making on Care Pathways and CAMs: A Pilot Study

Recruiting
N/A
100
Europe
alternative medicine education consultation
University Hospital, Grenoble, University Grenoble Alps, Laboratoire TIMC-IMAG
Breast Cancer, Non-metastatic, Newly Diagnosed, Feasibility Study
01/24
08/24
PROBREAST, NCT03436069: Identification of New Prognostic Markers for Breast Cancer.

Recruiting
N/A
1500
Europe
Conventional treatment protocols of breast cancer
University Hospital, Grenoble
Breast Cancer
12/33
12/33
Tamisier, Renaud
ENDOTHELION, NCT02377271 / 2014-000848-14: Study Group: Effect of Bosentan in NAION Patients

Recruiting
3
86
Europe
bosentan, placebo
University Hospital, Grenoble
Ischemic Optic Neuropathy
12/23
12/25
PLASTIHC, NCT05210088: PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke

Withdrawn
1/2
40
Europe
Hypoxia, intermittent, Hypoxic conditioning, Hypoxia, Normoxia
University Hospital, Grenoble, Agir pour les maladies chroniques
Stroke, Ischemic, Stroke Sequelae
01/24
01/24
Co-SURVIVORS, NCT04406324: COVID-19: Respiratory and Sleep Follow-up

Active, not recruiting
N/A
395
Europe
No intervention
University Hospital, Grenoble
COVID-19
03/22
06/26
AIRSTIM, NCT03844295: Obstructive Sleep Apnea Therapy by Stimulation of the Hypoglossal Nerve

Completed
N/A
7
Europe
Activated Inspire® Upper Airway Stimulation System, Inactivated Inspire® Upper Airway Stimulation System
University Hospital, Grenoble, Inspire Medical Systems, Inc.
Obstructive Sleep Apnea Syndrome
12/21
10/23
STIMOBIII, NCT02210585: Study of Neuromuscular Electrical Stimulation to Increase Spontaneous Physical Activity in Obesity Patient

Completed
N/A
73
Europe
Rehabilitation
University Hospital, Grenoble
Obesity, Number of Steps Per Day < 7000
05/24
05/24
AP-FLUID, NCT04623463: Effects of Physical Activity on OSA Severity Based on the Level of Fluid Shift

Recruiting
N/A
62
Europe
Physical activity intervention
University Hospital, Grenoble, HP2 Laboratory
Obstructive Sleep Apnea
10/26
10/26
FatCovid-19, NCT04363606: Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability

Terminated
N/A
65
Europe
Questionnaires, blood test, Maximal effort test, actigraphy, Neuromuscular evaluation, stool analysis, food diary
Centre Hospitalier Universitaire de Saint Etienne, University of Saint-Etienne, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
07/21
08/21
PWV follow-up, NCT04704401: Long-Term Follow-up in Patients Included in the Meta-analysis "Sleep Apnea Syndrome and Arterial Stiffness"

Recruiting
N/A
893
Europe
Questionnaire
University Hospital, Grenoble
Sleep Apnea
10/25
10/25
ESADAfollow-up, NCT04800341: Long-term Follow-up in Patients Included in the European Sleep Apnea Data Base (ESADA)

Recruiting
N/A
500
Europe
Questionnaire
University Hospital, Grenoble
Sleep Apnea
11/25
11/25
NCT02264431: Severe Obesity Outcome Network Cohort (SOON)

Recruiting
N/A
500
Europe
University Hospital, Grenoble, Act For Chronic Diseases, HP2 laboratory INSERM U1042, University Grenoble Alps
Obesity, Obstructive Sleep Apnea, Sleep
01/24
01/24
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis

Completed
N/A
848
Europe
Sunrise, polysomnography
Sunrise, ICUREsearch
Obstructive Sleep Apnea
10/24
10/24
NCT05197855: Sleep Quality Evolution: Dreem Under CPAP

Recruiting
N/A
70
Europe
Deem 3 Headband
University Hospital, Grenoble, Dreem, AGIR à Dom
Sleep Apnea, Obstructive Sleep Apnea
11/25
12/25
VISIOSAS, NCT04547543: Follow-up of Apneic Patients by Visio-consultation

Recruiting
N/A
250
Europe
Videoconsultation
University Hospital, Grenoble, University Hospital, Angers
Obstructive Sleep Apnea
03/26
03/26
ECO-COPD, NCT03014609: Cardiovascular Risk and Chronic Obstructive Pulmonary Disease

Recruiting
N/A
150
Europe
University Hospital, Grenoble
Chronic Obstructive Pulmonary Disease
11/29
12/29
ASCENT, NCT04399200: Apnea, Stroke and Incident Cardiovascular Events

Recruiting
N/A
1620
Europe
Treatment according to standard care recommandation
University Hospital, Grenoble
Stroke, Sleep-disordered Breathing, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Sleep Apnea, Central, Fragmentation, Sleep
06/30
06/35
TELEAP1, NCT04897646: The CPAP-telemonitoring Study

Recruiting
N/A
300
Europe
SFRMS/SPLF CPAP-telemonitoring diagnosis/therapeutic algorithm.
University Hospital, Montpellier, ADENE, Montpellier, AGIR à dom, Meylan, ASTEN sante, Pays de la Loire, ELIA medical, Cesson-Sévigné
Obstructive Sleep Apnea
12/21
12/23
REMAP, NCT05435794: Long-term Benefits of CPAP or MAD Treatment on the Sleep of OSAS Patients

Recruiting
N/A
400
Europe
CPAP, MAD
ResMed
OSA
10/22
10/26
Gentina, Thibaut
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP):

Terminated
N/A
41
Europe
CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France)
Obstructive Sleep Apnea Syndrome
01/24
02/24
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis

Completed
N/A
848
Europe
Sunrise, polysomnography
Sunrise, ICUREsearch
Obstructive Sleep Apnea
10/24
10/24
KRAINIK, Alexandre A
PLASTIHC, NCT05210088: PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke

Withdrawn
1/2
40
Europe
Hypoxia, intermittent, Hypoxic conditioning, Hypoxia, Normoxia
University Hospital, Grenoble, Agir pour les maladies chroniques
Stroke, Ischemic, Stroke Sequelae
01/24
01/24
ALLA, Corinne C ARAMARI
NEUROBLU 02, NCT03966651 / 2020-002996-36: A Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-DOTA0-Tyr3-Octreotate in Children With Refractory or Recurrent Neuroblastoma Expressing Somatostatin Receptors.

Recruiting
1
18
Europe
PRRT with 177Lu-DOTATATE
Institut Claudius Regaud, Advanced Accelerator Applications
Neuroblastoma
10/25
02/26
APADHOP, NCT06230016: Adhesion of Children and Adolescents Treated for Cancer to Personalized Support in Adapted Physical Activity Program

Recruiting
N/A
48
Europe
questionnaires, PedsQL quality of life questionnaires
University Hospital, Grenoble, University Grenoble Alps
Childhood Cancer, Adapted Physical Activity
08/25
01/26
ESCORT-HU Extension, NCT04707235: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study

Active, not recruiting
N/A
2093
Europe, RoW
Hydroxycarbamide, Siklos, Hydroxyurea
Theravia, International Clinical Trials Association
Sickle Cell Disease
08/25
08/25
ALARM3, NCT05772559: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies

Recruiting
N/A
500
Europe
Collection of blood sample of bone marrow (cohort 1), Collection of blood sample of bone marrow (cohort 2 and 3)
Assistance Publique - Hôpitaux de Paris
Acute Myeloid Leukemia, Genetic Predisposition to Disease
05/33
05/33
DURAND, CHANTAL C
ORACLE, NCT05100771: Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy

Recruiting
N/A
240
Europe
Pediatric brain MRI
University Hospital, Tours
Focal Epilepsy
03/25
03/25
Bouzat, Pierre
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype

Recruiting
3
450
Europe
Dexamethasone, Placebo
Nantes University Hospital
Hospital Acquired Pneumonia
03/26
08/26
T-STORHM, NCT04431999: Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage

Recruiting
3
200
Europe
Whole blood transfusion, Fractionated blood products transfusion
Direction Centrale du Service de Santé des Armées, TIMC-IMAG, Floralis
Trauma, Acute Hemorrhage, Coagulopathy
09/24
09/25
HYPNOTIKS, NCT06733129: Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room

Not yet recruiting
3
1218
Europe
direct IV injection, combination of Ketamine and Propofol
Nantes University Hospital
Rapid Sequence Induction
03/27
04/27
RADIOMIC-TBI, NCT04058379: Artificial Intelligence Analysis of Initial Scan Evolution of Traumatic Brain Injured Patient to Predict Neurological Outcome

Active, not recruiting
N/A
30
Europe
CT scan
University Hospital, Grenoble
Trauma, Brain
04/21
10/21
ALPACA, NCT06248736: Description of Lactulose Administration by Balloon Rectal Tube in Severe Hepatic Encephalopathy

Completed
N/A
25
Europe
University Hospital, Grenoble
Hepatic Encephalopathy
08/24
08/24
GAME-OVER, NCT05553054: Drug Wastage : Observational Study in Intensive Care Units in France

Completed
N/A
1066
Europe, RoW
Quantification of IV drugs wastage
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer, Sainte-Anne Military Teaching Hospital
Drug Use
03/23
03/23
FatCovid-19, NCT04363606: Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability

Terminated
N/A
65
Europe
Questionnaires, blood test, Maximal effort test, actigraphy, Neuromuscular evaluation, stool analysis, food diary
Centre Hospitalier Universitaire de Saint Etienne, University of Saint-Etienne, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
07/21
08/21
TRUST, NCT03989999: Transcranial Ultrasonography for the Management of Patients With Mild TBI

Recruiting
N/A
984
Europe, RoW
Transcranial Doppler (TCD)
University Hospital, Grenoble
Mild Traumatic Brain Injury
05/25
07/26
OPTI-TWO, NCT05893030: Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk

Recruiting
N/A
1132
Europe
anesthesia guided by sedation and analgesia monitoring, anesthesia performed according only to the clinical judgment of the anesthetist as usual practice
Centre Hospitalier Universitaire de Saint Etienne, Direction Générale de l'Offre de Soins
Sedation and Analgesia Monitoring
01/27
12/27
JAFFUEL, Dany
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP):

Terminated
N/A
41
Europe
CPAP associated with connected devices: blood pressure monitor , scales and activity monitor
University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France)
Obstructive Sleep Apnea Syndrome
01/24
02/24
JawRihn1, NCT04012216: Sleep Respiratory Disorders in Patients With Moderate to Severe Persistent Rhinitis

Completed
N/A
55
Europe
Measure of mandibular movement using a mid-sagittal magnetic sensor (Brizzy, Jawac©) Nomics, Liege, Belgium), Gold standard: polysomnography
University Hospital, Montpellier, ADENE
Rhinitis
06/24
11/24
TELEAP1, NCT04897646: The CPAP-telemonitoring Study

Recruiting
N/A
300
Europe
SFRMS/SPLF CPAP-telemonitoring diagnosis/therapeutic algorithm.
University Hospital, Montpellier, ADENE, Montpellier, AGIR à dom, Meylan, ASTEN sante, Pays de la Loire, ELIA medical, Cesson-Sévigné
Obstructive Sleep Apnea
12/21
12/23
Plantaz, Dominique
CAALL-F01, NCT02716233: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents

Recruiting
3
1578
Europe
pegaspargase 1250 IU/m2 x 2, ONCASPAR 1250 IU/m2 x 2, pegaspargase 2500 IU/m2 x 1, ONCASPAR 2500 IU/m2 x 1
Assistance Publique - Hôpitaux de Paris, Shire
Acute Lymphoblastic Leukemia
04/26
04/26
HR-NBL2, NCT04221035 / 2019-001068-31: High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)

Recruiting
3
800
Europe, RoW
Vincristine, L01CA02, Carboplatin, LO1XA02, Etoposide, L01CB01, Vindesine, L01CA03, Dacarbazine, L01AX04, Ifosfamide, Doxorubicin, L01DB01, Busulfan, L01AB01, Melphalan, L01AA03, Thiotepa, L01AC01, Radiotherapy, Dinutuximab Beta, L01XC16, Cisplatin, L01XA01, Temozolomide 100 MG, Irinotecan, Cyclophosphamid
Gustave Roussy, Cancer Campus, Grand Paris, PHRC, Solving Kids' Cancer Europe, Neuroblastoma UK, , BSPHO, Instituto de Investigación Sanitaria La Fe, Deutsche Krebshilfe
High-Risk Neuroblastoma, Patient With Insufficient Response Chemoimmunotherapy
11/26
11/32
FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
2/3
1800
Europe, Canada, RoW
VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin
St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group
Acute Lymphoblastic Leukaemia
06/25
04/30
RETINO2018, NCT04681417 / 2019-005039-94: Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome

Recruiting
2/3
225
Europe
Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma
01/35
01/36
RETINO2011, NCT02866136: Conservative Treatments of Retinoblastoma

Active, not recruiting
2
133
Europe
VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma, Children, Retinal Neoplasm
01/23
09/35
NCT02870907 / 2009-016448-38: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)

Recruiting
2
185
Europe
Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation
Institut Curie
Retinoblastoma
03/30
09/30
MetroWilms, NCT05384821: Metronomic Chemotherapy in Wilms Tumor (-1906)

Recruiting
1/2
28
Europe
Vincristine, Irinotecan, Temozolomide, Etoposide, Cis-Retinoic acid
Centre Oscar Lambret
Wilms Tumor
05/28
10/28
CURALASE01, NCT04596410: Photobiomodulation Protocols in the Analgesia of Chemotherapy-induced Oral Mucositis in Children

Recruiting
N/A
406
Europe
LLLT applied every other day, LLLT applied daily
University Hospital, Toulouse
Mucositis Oral
01/24
02/24
EXOCARE, NCT03472807: EXOme Rare Cancers in Children

Recruiting
N/A
300
Europe, RoW
Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
University Hospital, Angers
Predisposition, Genetic, Cancer Childhood, Development Delay
02/25
08/25
SACHA, NCT04477681: Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults

Recruiting
N/A
1000
Europe
Data collection
Gustave Roussy, Cancer Campus, Grand Paris, Société Française des Cancers de l'Enfant (SFCE)
Pediatric Cancer
04/26
04/27
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults

Active, not recruiting
N/A
600
Europe
Sampling on blood, bone marrow and cerebrospinal fluid
Institut Curie
Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor
04/27
08/27
Minotti, Lorella
REPREO, NCT05609084: Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy

Recruiting
N/A
214
Europe
Speech therapy, Speech therapy assessment
Assistance Publique Hopitaux De Marseille
Epilepsy, Anomia, Temporal Lobe Epilepsy
03/27
11/27
Llerena, Catherine
Lum-Iva-Biota, NCT03565692: Lum-Iva-biota: Exploring the Respiratory Mycobiota and Microbiota Profile in French CF Patients Taking Lumacaftor-Ivacaftor

Recruiting
N/A
250
Europe
the lung mycobiota and microbiota profile, the gut mycobiota and microbiota profile
University Hospital, Bordeaux, Societe Francaise de la Mucoviscidose
Cystic Fibrosis
02/23
02/23
KAF-BIOTA, NCT05937815: Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor

Recruiting
N/A
253
Europe
Sample collection
University Hospital, Bordeaux
Cystic Fibrosis
09/23
09/24
CAR-CF, NCT05614336: COVID-19 Antibody Responses in Cystic Fibrosis

Active, not recruiting
N/A
331
Europe
Blood sample
Hospices Civils de Lyon, Queen's University, Belfast
COVID-19, Cystic Fibrosis
06/25
06/25
MUKADO, NCT05795673: Peer-supporting for Teenagers With Cystic Fibrosis in the Transition of Care From Paediatric to Adult Services

Not yet recruiting
N/A
88
Europe
Peer support program (intervention phase)
Hospices Civils de Lyon
Cystic Fibrosis
09/26
09/26
SCHIFF, Isabelle I
APADHOP, NCT06230016: Adhesion of Children and Adolescents Treated for Cancer to Personalized Support in Adapted Physical Activity Program

Recruiting
N/A
48
Europe
questionnaires, PedsQL quality of life questionnaires
University Hospital, Grenoble, University Grenoble Alps
Childhood Cancer, Adapted Physical Activity
08/25
01/26
TOFFART, Anne-Claire
NIVOTHYM, NCT03134118 / 2015-005504-28: Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma

Active, not recruiting
2
55
Europe
Nivolumab, BMS-936558-01
European Organisation for Research and Treatment of Cancer - EORTC, ETOP IBCSG Partners Foundation
Thymoma Type B3, Thymic Carcinoma
12/23
07/24
METABO-ICI, NCT04189679: Identification of a Predictive Metabolic Signature of Response to Immune Checkpoint Inhibitors in Non-Small Cell Lung Carcinoma

Completed
N/A
62
Europe
Immune signature in serum associated to the metabolic signature, Meta-genomic signature of intestinal flora
University Hospital, Grenoble
Non Small Cell Lung Cancer
01/23
01/23
PACT-01, NCT04823377: Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer.

Recruiting
N/A
364
Europe
Usual care, Optimization of the medical decision
Institut Curie
Carcinoma, Non-Small-Cell Lung, Advanced Cancer
09/26
09/27
SPECTA, NCT02834884: Screening Cancer Patients for Efficient Clinical Trial Access

Recruiting
N/A
4975
Europe, RoW
RP-1828 IMMUcan, RP-1759 AYA/TYA, RP-1843 Arcagen, RP-1920 BioRadon
European Organisation for Research and Treatment of Cancer - EORTC
All Tumor Types
03/26
03/26
PRIMALung, NCT04790253: PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients ( Study)

Recruiting
N/A
600
Europe
Prophylactic cranial irradiation
European Organisation for Research and Treatment of Cancer - EORTC, UNICANCER
Limited Stage Small Cell Lung Cancer, Extensive-stage Small-cell Lung Cancer
04/28
04/28
ROSIE, NCT06053099: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)

Recruiting
N/A
300
Europe
Plasma ctDNA, FFPE blocks
Intergroupe Francophone de Cancerologie Thoracique
Non Small Cell Lung Cancer, EGFR Activating Mutation, EGFR DEL19, EGFR L858R
10/31
10/31
MOUSSSEAU, Mireille
PROBREAST, NCT03436069: Identification of New Prognostic Markers for Breast Cancer.

Recruiting
N/A
1500
Europe
Conventional treatment protocols of breast cancer
University Hospital, Grenoble
Breast Cancer
12/33
12/33

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