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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Aliberti, Sandra
FIBROSARC, NCT04650984 / 2016-003239-38: A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma	Recruiting	3	102	Europe	Onfekafusp alfa, L19TNF, Doxorubicin	Philogen S.p.A.	Soft Tissue Sarcoma	12/25	12/25
TANGENT, NCT05417789: Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)	Recruiting	3	128	Europe, Canada, US, RoW	Emactuzumab, Placebo	SynOx Therapeutics Limited	TGCT	04/26	09/27
SUNRISELMS, NCT05269355 / 2022-000073-12: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)	Terminated	2/3	359	Europe, Canada, US, RoW	Unesbulin, PTC596, Dacarbazine, DTIC, Placebo	PTC Therapeutics, PTC Therapeutics, Inc.	Leiomyosarcoma	06/24	07/24
FLASH, NCT04733183 / 2018-004104-19: Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma	Active, not recruiting	2	98	Europe	Dacarbazine, DTIC, onfekafusp alfa, L19TNF	Philogen S.p.A., Philogen S.p.A.,	Soft Tissue Sarcoma	12/25	12/25
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma	Recruiting	2	201	Europe, US, RoW	INBRX-109, Placebo	Inhibrx Biosciences, Inc	Conventional Chondrosarcoma	09/25	12/26
ISG-ARTICLE, NCT04383119 / 2020-000741-13: Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma	Recruiting	2	100	Europe	Trabectedin, Trabectedin arm, Gemcitabine, Gemcitabine arm, No Intervention: Observational Cohort	Italian Sarcoma Group, PharmaMar	Leiomyosarcoma of Ovary, Soft Tissue Sarcoma	12/25	12/25
ISG-MCS, NCT04305548 / 2019-003733-41: Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma	Recruiting	2	16	Europe	Trabectedin	Italian Sarcoma Group, PharmaMar	Mesenchymal Chondrosarcoma	08/25	12/25
NCT03715933: Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas	Recruiting	1	321	Europe, US	INBRX-109, Carboplatin, Cisplatin, Pemetrexed, 5-fluorouracil, Irinotecan, Temozolomide	Inhibrx Biosciences, Inc	Colorectal Adenocarcinoma, Ewing Sarcoma	06/26	12/26
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma	Recruiting	N/A	120	Europe	Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)	Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica	Localized Osteosarcoma	06/26	12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma	Recruiting	N/A	100	Europe	Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)	Italian Sarcoma Group	Ewing Sarcoma of Bone	05/28	05/28

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Aliberti, Sandra
FIBROSARC, NCT04650984 / 2016-003239-38: A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma	Recruiting	3	102	Europe	Onfekafusp alfa, L19TNF, Doxorubicin	Philogen S.p.A.	Soft Tissue Sarcoma	12/25	12/25
TANGENT, NCT05417789: Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)	Recruiting	3	128	Europe, Canada, US, RoW	Emactuzumab, Placebo	SynOx Therapeutics Limited	TGCT	04/26	09/27
SUNRISELMS, NCT05269355 / 2022-000073-12: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)	Terminated	2/3	359	Europe, Canada, US, RoW	Unesbulin, PTC596, Dacarbazine, DTIC, Placebo	PTC Therapeutics, PTC Therapeutics, Inc.	Leiomyosarcoma	06/24	07/24
FLASH, NCT04733183 / 2018-004104-19: Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma	Active, not recruiting	2	98	Europe	Dacarbazine, DTIC, onfekafusp alfa, L19TNF	Philogen S.p.A., Philogen S.p.A.,	Soft Tissue Sarcoma	12/25	12/25
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma	Recruiting	2	201	Europe, US, RoW	INBRX-109, Placebo	Inhibrx Biosciences, Inc	Conventional Chondrosarcoma	09/25	12/26
ISG-ARTICLE, NCT04383119 / 2020-000741-13: Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma	Recruiting	2	100	Europe	Trabectedin, Trabectedin arm, Gemcitabine, Gemcitabine arm, No Intervention: Observational Cohort	Italian Sarcoma Group, PharmaMar	Leiomyosarcoma of Ovary, Soft Tissue Sarcoma	12/25	12/25
ISG-MCS, NCT04305548 / 2019-003733-41: Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma	Recruiting	2	16	Europe	Trabectedin	Italian Sarcoma Group, PharmaMar	Mesenchymal Chondrosarcoma	08/25	12/25
NCT03715933: Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas	Recruiting	1	321	Europe, US	INBRX-109, Carboplatin, Cisplatin, Pemetrexed, 5-fluorouracil, Irinotecan, Temozolomide	Inhibrx Biosciences, Inc	Colorectal Adenocarcinoma, Ewing Sarcoma	06/26	12/26
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma	Recruiting	N/A	120	Europe	Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)	Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica	Localized Osteosarcoma	06/26	12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma	Recruiting	N/A	100	Europe	Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)	Italian Sarcoma Group	Ewing Sarcoma of Bone	05/28	05/28