A.O. Seconda Università Degli Studi di Napoli - Nuovo Policlinico - UOC Oftalmologia
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 3 Trials 
6 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Simonelli, Francesca
NCT04671433 / 2020-002873-88: Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Active, not recruiting
3
97
Europe, Canada, US, RoW
Genetic: AAV5-hRKp.RPGR, botaretigene sparoparvovec
Janssen Research & Development, LLC, Janssen Research & Development, LLC
X-Linked Retinitis Pigmentosa
09/24
09/24
MGT-RPGR-022, NCT04794101 / 2020-002255-37: Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

Active, not recruiting
3
97
Europe, Canada, US, RoW
Genetic: AAV5-hRKp.RPGR Intermediate Dose, botaretigene sparoparvovec, Genetic: AAV5-hRKp.RPGR Low Dose
Janssen Research & Development, LLC, Janssen Research & Development, LLC
X-Linked Retinitis Pigmentosa
09/29
12/29
BRIGHTEN, NCT04855045 / 2020-000535-45: An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.

Recruiting
2/3
15
Europe, Canada, RoW
sepofarsen, QR-110
ProQR Therapeutics
Leber Congenital Amaurosis 10, Blindness, Leber Congenital Amaurosis, Vision Disorders, Sensation Disorders, Neurologic Manifestations, Eye Diseases, Eye Disorders Congenital, Retinal Disease, Retinal Degeneration, Retinal Dystrophies
12/23
12/23
NCT06591793: Study of Subretinally Injected AAVB-081 in Patients With Usher Syndrome Type IB (USH1B) Retinitis Pigmentosa

Recruiting
1/2
15
Europe
AAVB-081
AAVantgarde Bio Srl
Usher Syndrome, Type 1B
07/25
07/29
DRUSEN, NCT06046118: Photobiomodulation in Dry Age Related Macular Degeneration

Recruiting
N/A
180
Europe, RoW
Yellow and red light emitting diode photobiomodulation (Eye Light, Espansione Group, Bologna, Italy), Sham Mask
Azienda Ospedaliera Universitaria Mater Domini, Catanzaro
Age-Related Macular Degeneration
12/24
12/24
RPE65-NHS, NCT04525261: Natural History of Patients With Inherited Retinal Diseases Due to Mutations in RPE65 Gene

Completed
N/A
60
Europe
University of Campania "Luigi Vanvitelli", Retina Italia Onlus
Leber Congenital Amaurosis 2, Retinitis Pigmentosa 20
07/20
07/20
Melillo, Paolo
No trials found

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