| Jin, Yang |
NCT04101500: Effect of Compound Sodium Chlorate and Aminophylline Tablets on Chronic Obstructive Pulmonary Disease(COPD). |
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| Recruiting | 4 | 200 | RoW | Compound Ipratropium Bromide Solution(C1) for Inhalation, CIBS(C1), Compound Sodium Chlolate and Aminophylline Tablets(C2), CSCAT(C2), Placebo Tablets, PT | Wuhan Union Hospital, China | Acute Exacerbation of Chronic Obstructive Pulmonary Disease | 12/20 | 12/24 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT06647836: The Therapeutic Effect of Immunotherapy in Patients With Advanced Lung Squamous Carcinoma |
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| Enrolling by invitation | N/A | 1000 | RoW | Efficacy observation | Wuhan Union Hospital, China | Squamous Cell Lung Cancer | 12/26 | 12/27 | | |
NCT06653478: Development and Demonstration of Intelligent Assessment Based on Multi-modal Information Fusion for Tumor Risk and Diagnosis and Treatment |
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| Recruiting | N/A | 3000 | RoW | No Intervention | Wuhan Union Hospital, China | Artificial Intelligence, Deep Learning, Lung Cancer, Lung; Node, Stomach Cancer, Colon Cancer, Cancer Risk, Cancer Screening, Cancer, Treatment-Related | 10/25 | 10/26 | | |
NCT04183530: The Individualized Accurate Diagnosis and Treatment of Chronic Objective Pulmonary Disease(COPD) Patients Based on Multidimensional Data |
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| Recruiting | N/A | 1000 | RoW | | Wuhan Union Hospital, China | Copd, Acute Exacerbation of Chronic Obstructive Pulmonary Disease | 10/22 | 12/24 | | |
NCT04005677: The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages |
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| Recruiting | N/A | 500 | RoW | The serum, plasma, urine, faeces, peripheral blood mononuclear cell (PBMC), exhaled breath condensate and the clinical characteristics are collected. | Wuhan Union Hospital, China | Pulmonary Nodule, Solitary, Lung; Node | 12/22 | 12/24 | | |
NCT05046366: Development of an Artificial Intelligence System for Intelligent Pathological Diagnosis and Therapeutic Effect Prediction Based on Multimodal Data Fusion of Common Tumors and Major Infectious Diseases in the Respiratory System Using Deep Learning Technology. |
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| Recruiting | N/A | 1000 | RoW | | Wuhan Union Hospital, China | Artificial Intelligence, Deep Learning, Pathology, Molecular, Medical Informatics, Database, Lung Cancer, Pulmonary Tuberculosis, Covid19 | 12/23 | 12/24 | | |
NCT04456101: Study on the Recovery of Pulmonary Function, Chest CT, Airway Microbiota, Hematologic, and Immune & Inflammatory Conditions in COVID-19 Rehabilitation Patients |
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| Recruiting | N/A | 450 | RoW | | Wuhan Union Hospital, China | COVID-19 | 12/23 | 12/23 | | |
NCT06645223: Correlation Between Gut Microbiota and Pancreatic Β-Cell Function in Diabetic Patients |
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| Enrolling by invitation | N/A | 160 | RoW | No Interventions | Peking University Third Hospital | Diabetes Mellitus, Gut Microbiota | 12/25 | 07/26 | | |
NCT05830812: Improving the Intraoperative Diagnosis Accuracy of Invasiveness for Small-sized Lung Adenocarcinoma |
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| Recruiting | N/A | 3000 | RoW | Invasiveness diagnosis | Wuhan Union Hospital, China | Lung Adenocarcinoma, Stage I | 12/25 | 12/26 | | |
NCT05426135: Artificial Intelligence System for Assessment of Tumor Risk and Diagnosis and Treatment |
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| Recruiting | N/A | 3000 | RoW | | Wuhan Union Hospital, China | Artificial Intelligence, Deep Learning, Lung Cancer, Lung; Node, Stomach Cancer, Colon Cancer, Cancer Risk, Cancer Screening, Cancer, Treatment-Related | 10/25 | 10/26 | | |
| Yang, Chao |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT04370925: Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis |
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| Recruiting | 3 | 688 | RoW | Radical colectomy, HIPEC, Systemic chemotherapy | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Nanfang Hospital of Southern Medical University, Sun Yat-sen University, Sixth Affiliated Hospital, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangdong Provincial People's Hospital, Meizhou People's Hospital, First People's Hospital of Foshan, Shantou Central Hospital, Jiangmen Central Hospital, Shenzhen Second People's Hospital, Zhongshan People's Hospital, Guangdong, China, ZhuHai Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing Cancer Hospital, Peking University People's Hospital, Fudan University, The Second Affiliated Hospital of Chongqing Medical University, Chongqing University Cancer Hospital, First Affiliated Hospital of Chongqing Medical University, Second Affiliated Hospital, School of Medicine, Zhejiang University, Wuhan Union Hospital, China, Renmin Hospital of Wuhan University, Wuhan University, Sichuan Provincial People's Hospital, West China Hospital, The People's Hospital of Leshan, People’s Hospital of Deyang City, Hebei Medical University Fourth Hospital, The First Affiliated Hospital of Nanchang University, The Affiliated Hospital Of Southwest Medical University, The Affiliated Hospital of Xuzhou Medical University, People's Hospital of Guangxi, The Third People's Hospital of Chengdu, The Affiliated Tumor Hospital of Guangxi Medical University | Colorectal Cancer | 04/24 | 04/26 | | |
| Cui, Guohui |
BRUIN CLL-313, NCT05023980: A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) |
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| Active, not recruiting | 3 | 250 | Europe, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Bendamustine, Treanda, Treakisym, Ribomustin, Levact, Rituximab, Rituxan, MabThera, Truxima, Riabni, Ruxience | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 04/25 | 08/26 | | |
NCT04578613: ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL |
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| Recruiting | 3 | 218 | RoW | ICP-022, Chlorambucil, Rituximab | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/24 | 06/25 | | |
NCT05051891: A Randomized, Open-label, Multi-center, Phase III Study of Orelabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) vs. R-CHOP Alone in Patients With Treatment-naїve Mantle Cell Lymphoma |
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| Recruiting | 3 | 356 | RoW | Orelabrutinib and R-CHOP, R-CHOP | Beijing InnoCare Pharma Tech Co., Ltd. | Treatment-naїve Mantle Cell Lymphoma | 12/24 | 12/27 | | |
| Active, not recruiting | 3 | 500 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib, Imbruvica, Acalabrutinib, Calquence, Zanubrutinib, Brukinsa | Loxo Oncology, Inc., Eli Lilly and Company | Lymphoma, Mantle-Cell | 12/25 | 07/26 | | |
BRUIN CLL-322, NCT04965493 / 2021-000043-49: A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) |
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| Recruiting | 3 | 600 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Venetoclax, Venclexta, Venclyxto, Rituximab, Rituxan, MabThera, Truxima, Riabni, Ruxience | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 04/26 | 01/27 | | |
| Active, not recruiting | 3 | 650 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic, Leukemia, B-cell, Small Lymphocytic Lymphoma | 06/25 | 01/28 | | |
ICP-CL-01203, NCT06378138: ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma |
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| Recruiting | 2/3 | 226 | RoW | ICP-248, Orelabrutinib | Beijing InnoCare Pharma Tech Co., Ltd. | Hematologic Malignancies | 11/30 | 07/31 | | |
NCT05147467: Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL |
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| Recruiting | 2 | 75 | RoW | APG2575 | Ascentage Pharma Group Inc. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 09/24 | 12/24 | | |
NCT05978739: Evaluating Different Doses of Orelabrutinib in MCL |
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| Recruiting | 2 | 40 | RoW | Orelabrutinib High dose, Orelabrutinib Low dose | InnoCare Pharma Inc., Beijing InnoCare Pharma Tech Co., Ltd. | Mantle Cell Lymphoma | 02/25 | 05/25 | | |
NCT05269940: A Study to Evaluate Activity, Safety and Tolerability of ZX-101A in Relapsed/Refractory Hematological Malignancies |
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| Completed | 1/2 | 40 | RoW | ZX-101A | Nanjing Zenshine Pharmaceuticals | Non Hodgkin Lymphoma, Peripheral T Cell Lymphoma, CLL/SLL | 01/23 | 07/24 | | |
NCT04494503: Study of APG2575 Single Agent and Combination Therapy in Patients With Relapsed/Refractory CLL/SLL |
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| Recruiting | 1/2 | 123 | RoW | APG-2575, Rituximab, Ibrutinib | Ascentage Pharma Group Inc. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/24 | 12/25 | | |
| Recruiting | 1 | 100 | RoW | HMPL-760 | Hutchison Medipharma Limited | B-Cell Non-Hodgkin's Lymphoma | 07/24 | 04/26 | | |
| Recruiting | 1 | 191 | RoW | ICP-248, ICP-248+Orelabrutinib | Beijing InnoCare Pharma Tech Co., Ltd. | Hematological Malignancies | 08/25 | 10/26 | | |
| Completed | N/A | 1006 | RoW | | Takeda | Lymphoma | 07/24 | 07/24 | | |
NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma |
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| Active, not recruiting | N/A | 1000 | RoW | No Intervention | Takeda | Lymphoma | 06/26 | 06/26 | | |
| Xie, Min |
| Active, not recruiting | 4 | 640 | RoW | Tenofovir Amibufenamide（TMF）, HS-10234 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Hepatitis B, Chronic | 06/24 | 09/29 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
| Huang, Jian-an |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
