Colin Grissom
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 29 Trials 
25 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lanspa, Michael
NECTAR, NCT04924660: Novel Experimental COVID-19 Therapies Affecting Host Response

Completed
2/3
871
US
TXA127, TRV027, Placebo, Fostamatinib
Sean Collins, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
COVID-19, SARS-CoV-2 Infection, Coronavirus Infection
10/23
12/23
NCT03913403: Study of Treatment's Echocardiographic Mechanisms

Recruiting
N/A
210
US
ECHO, Blood Draw
Intermountain Health Care, Inc., Beth Israel Deaconess Medical Center, Montefiore Medical Center, Oregon Health and Science University, Vanderbilt University Medical Center, Wake Forest University Health Sciences, Harborview Injury Prevention and Research Center
Sepsis
05/21
05/21
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
Brown, Samuel
NCT06729593: Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

Completed
3
87
US
Remdesivir, Remdesivir Placebo, Corticosteroid
National Institute of Allergy and Infectious Diseases (NIAID), International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), University of Copenhagen, Medical Research Council, Kirby Institute, Washington D.C. Veterans Affairs Medical Center, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, US Department of Veterans Affairs, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network, Gilead Sciences
Covid19
08/22
11/22
NCT06729606: Aviptidil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

Completed
3
471
US
Aviptidil, Vasoactive Intestinal Peptide, VIP, Aviptidil Placebo, Corticosteroid
National Institute of Allergy and Infectious Diseases (NIAID), International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), University of Copenhagen, Medical Research Council, Kirby Institute, Washington D.C. Veterans Affairs Medical Center, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, US Department of Veterans Affairs, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network, NeuroRx, Inc.
Covid19
08/22
11/22
NCT03913403: Study of Treatment's Echocardiographic Mechanisms

Recruiting
N/A
210
US
ECHO, Blood Draw
Intermountain Health Care, Inc., Beth Israel Deaconess Medical Center, Montefiore Medical Center, Oregon Health and Science University, Vanderbilt University Medical Center, Wake Forest University Health Sciences, Harborview Injury Prevention and Research Center
Sepsis
05/21
05/21
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
APICS, NCT03738774: Addressing Post-Intensive Care Syndrome Among Survivors of COVID (-COVID)

Active, not recruiting
N/A
200
US
Vanderbilt University Medical Center, United States Department of Defense
Post Intensive Care Syndrome
07/25
07/25
NCT06521502: The APS Phenotyping Study

Recruiting
N/A
4000
US
Blood collection, Urine Collection, Nasal, oral, and rectal swabs, Stool collection, Heat Moisture Exchange Filter collection, Tracheal Aspirate sample collection, Non-bronchoscopic bronchoalveolar lavage (NBBAL), Surveys, Short physical performance battery, Hand grip strength, CNS Vital Signs, Muscle Ultrasound, Muscle Strength, Spirometry, Lung Diffusion Testing (DLCO), Chest CT Scan
Vanderbilt University Medical Center
ARDS, Sepsis, Pneumonia
04/28
04/28
SPARTAN, NCT05916092: Post-Market Clinical Study on a Modular SI Joint Fusion System

Enrolling by invitation
N/A
240
US
TransLoc 3D
CornerLoc
Sacroiliitis, Sacroiliac Joint Dysfunction
12/25
07/26
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Peltan, Ithan
VASSPR, NCT06217562: Vasopressin for Septic Shock Pragmatic Trial

Enrolling by invitation
4
2050
US
Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin
Intermountain Health Care, Inc., University of Utah
Septic Shock
07/26
12/27
GRAIL^3, NCT04706507: Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Active, not recruiting
3
500
US
IV Ganciclovir, Cytovene
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Failure
10/24
08/27
NCT05996835: Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (SA-AKI)

Recruiting
2
320
Europe, Canada, Japan, US, RoW
TIN816 70 mg lyophilisate powder, Placebo
Novartis Pharmaceuticals
Acute Kidney Injury Due to Sepsis
12/25
02/26
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
Code Sepsis, NCT04148989: Effects of Implementation on Emergency Department (ED) Sepsis Care

Completed
N/A
180402
US
Code Sepsis protocol (full implementation)
Intermountain Health Care, Inc., National Institute of General Medical Sciences (NIGMS)
Sepsis
01/23
12/23
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Grissom, Colin
NEUROVENT, NCT03243539: Implementation of Neuro Lung Protective Ventilation

Active, not recruiting
N/A
728
US
Lung Protective Ventilation
Colin Grissom
Acute Brain Injury, Traumatic Brain Injury, Intracerebral Hemorrhage, Stroke, Cerebral Edema, Anoxic Brain Injury
12/18
12/24
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Miller, Russ
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
Collingridge, Dave
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lanspa, Michael
NECTAR, NCT04924660: Novel Experimental COVID-19 Therapies Affecting Host Response

Completed
2/3
871
US
TXA127, TRV027, Placebo, Fostamatinib
Sean Collins, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
COVID-19, SARS-CoV-2 Infection, Coronavirus Infection
10/23
12/23
NCT03913403: Study of Treatment's Echocardiographic Mechanisms

Recruiting
N/A
210
US
ECHO, Blood Draw
Intermountain Health Care, Inc., Beth Israel Deaconess Medical Center, Montefiore Medical Center, Oregon Health and Science University, Vanderbilt University Medical Center, Wake Forest University Health Sciences, Harborview Injury Prevention and Research Center
Sepsis
05/21
05/21
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
Brown, Samuel
NCT06729593: Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

Completed
3
87
US
Remdesivir, Remdesivir Placebo, Corticosteroid
National Institute of Allergy and Infectious Diseases (NIAID), International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), University of Copenhagen, Medical Research Council, Kirby Institute, Washington D.C. Veterans Affairs Medical Center, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, US Department of Veterans Affairs, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network, Gilead Sciences
Covid19
08/22
11/22
NCT06729606: Aviptidil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial)

Completed
3
471
US
Aviptidil, Vasoactive Intestinal Peptide, VIP, Aviptidil Placebo, Corticosteroid
National Institute of Allergy and Infectious Diseases (NIAID), International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), University of Copenhagen, Medical Research Council, Kirby Institute, Washington D.C. Veterans Affairs Medical Center, Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, US Department of Veterans Affairs, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network, NeuroRx, Inc.
Covid19
08/22
11/22
NCT03913403: Study of Treatment's Echocardiographic Mechanisms

Recruiting
N/A
210
US
ECHO, Blood Draw
Intermountain Health Care, Inc., Beth Israel Deaconess Medical Center, Montefiore Medical Center, Oregon Health and Science University, Vanderbilt University Medical Center, Wake Forest University Health Sciences, Harborview Injury Prevention and Research Center
Sepsis
05/21
05/21
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
APICS, NCT03738774: Addressing Post-Intensive Care Syndrome Among Survivors of COVID (-COVID)

Active, not recruiting
N/A
200
US
Vanderbilt University Medical Center, United States Department of Defense
Post Intensive Care Syndrome
07/25
07/25
NCT06521502: The APS Phenotyping Study

Recruiting
N/A
4000
US
Blood collection, Urine Collection, Nasal, oral, and rectal swabs, Stool collection, Heat Moisture Exchange Filter collection, Tracheal Aspirate sample collection, Non-bronchoscopic bronchoalveolar lavage (NBBAL), Surveys, Short physical performance battery, Hand grip strength, CNS Vital Signs, Muscle Ultrasound, Muscle Strength, Spirometry, Lung Diffusion Testing (DLCO), Chest CT Scan
Vanderbilt University Medical Center
ARDS, Sepsis, Pneumonia
04/28
04/28
SPARTAN, NCT05916092: Post-Market Clinical Study on a Modular SI Joint Fusion System

Enrolling by invitation
N/A
240
US
TransLoc 3D
CornerLoc
Sacroiliitis, Sacroiliac Joint Dysfunction
12/25
07/26
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Peltan, Ithan
VASSPR, NCT06217562: Vasopressin for Septic Shock Pragmatic Trial

Enrolling by invitation
4
2050
US
Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin
Intermountain Health Care, Inc., University of Utah
Septic Shock
07/26
12/27
GRAIL^3, NCT04706507: Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Active, not recruiting
3
500
US
IV Ganciclovir, Cytovene
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Failure
10/24
08/27
NCT05996835: Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (SA-AKI)

Recruiting
2
320
Europe, Canada, Japan, US, RoW
TIN816 70 mg lyophilisate powder, Placebo
Novartis Pharmaceuticals
Acute Kidney Injury Due to Sepsis
12/25
02/26
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
NCT03984175: Clinical Decision Support for Mechanical Ventilation of Patients With ARDS

Recruiting
N/A
350
US
Implementation of Processes
Intermountain Health Care, Inc., National Institutes of Health (NIH), McKay-Dee Hospital, Utah Valley Hospital, Dixie Regional Hospital
Acute Respiratory Distress Syndrome
12/22
12/22
Code Sepsis, NCT04148989: Effects of Implementation on Emergency Department (ED) Sepsis Care

Completed
N/A
180402
US
Code Sepsis protocol (full implementation)
Intermountain Health Care, Inc., National Institute of General Medical Sciences (NIGMS)
Sepsis
01/23
12/23
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Grissom, Colin
NEUROVENT, NCT03243539: Implementation of Neuro Lung Protective Ventilation

Active, not recruiting
N/A
728
US
Lung Protective Ventilation
Colin Grissom
Acute Brain Injury, Traumatic Brain Injury, Intracerebral Hemorrhage, Stroke, Cerebral Edema, Anoxic Brain Injury
12/18
12/24
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
TEACH, NCT05141396: Telehealth-Enabled, Real-time Audit and Feedback for Clinician AdHerence

Recruiting
N/A
13400
US
Telehealth- enabled support for SAT/SBT adherence, Usual audit and feedback for SAT/SBT adherence
Intermountain Health Care, Inc., University of Utah, National Heart, Lung, and Blood Institute (NHLBI)
Respiration, Artificial
08/26
10/26
Miller, Russ
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22
Collingridge, Dave
IMPROVENT, NCT03225807: Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure

Completed
N/A
8692
US
Intermountain Health Care, Inc.
Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Respiratory Distress Syndrome, Shock Lung, Severe Acute Respiratory Syndrome
12/22
12/22

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