| Thompson, John |
NCT05307341: Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA) |
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| Recruiting | 4 | 100 | US | sufentanil, sufentanil (DSUVIA) | More Foundation | Pain | 06/23 | 06/23 | | |
| Recruiting | 2 | 380 | US | IVIG + Coordinated Care, IVIG Placebo + Coordinated Care, Ivabradine + Coordinated Care, Ivabradine Placebo + Coordinated Care, IVIG + Usual Care, IVIG Placebo + Usual Care, Ivabradine + Usual Care, Ivabradine Placebo + Usual Care | Kanecia Obie Zimmerman | Long COVID, Long Covid19, Long Covid-19 | 12/25 | 03/26 | | |
MAGNIFY, NCT05893537: Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants with Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD). |
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| Active, not recruiting | 2 | 100 | US | Active Comparator CT1812, Placebo Comparator | Cognition Therapeutics | Age-Related Macular Degeneration | 07/27 | 08/27 | | |
PYNNACLE, NCT04585750: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation |
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| Recruiting | 1/2 | 230 | Europe, US, RoW | PC14586, rezatapopt, pembrolizumab, KEYTRUDA®, MK-3475, KEYNOTE-D79, MK-3475-D79 | PMV Pharmaceuticals, Inc, Merck Sharp & Dohme LLC | Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Prostate Cancer, Colorectal Cancer, Breast Cancer, Other Cancer, Locally Advanced, Head and Neck Cancer | 03/26 | 07/26 | | |
NCT03377569: Subcortical Oscillations in Human Sleep Dysregulation |
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| Active, not recruiting | N/A | 15 | US | Sleep, PD and DBS | University of Colorado, Denver | Parkinson Disease, REM Behavior Disorder | 08/20 | 12/24 | | |
NCT04620551: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease |
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| Active, not recruiting | N/A | 20 | US | Sub-clinical stimulation | University of Nebraska, Stanford University, University of Colorado, Denver, University of Pennsylvania | Parkinson Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
| Kushida, Clete A |
NCT05668754: Placebo-Controlled, Double-Blind, Study to Determine the Safety and Efficacy of SDX in Patients With IH |
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| Completed | 2 | 50 | US | Serdexmethylphenidate, SDX, Placebo | Zevra Therapeutics, Rho, Inc. | Idiopathic Hypersomnia | 02/24 | 03/24 | | |
NCT04620551: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease |
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| Active, not recruiting | N/A | 20 | US | Sub-clinical stimulation | University of Nebraska, Stanford University, University of Colorado, Denver, University of Pennsylvania | Parkinson Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
| Terminated | N/A | 35 | US | ProSomnus® EVO Sleep and Snore Device | ProSomnus Sleep Technologies | Obstructive Sleep Apnea, Sleep Apnea | 02/24 | 02/24 | | |
NCT02907398: Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry |
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| Active, not recruiting | N/A | 5000 | Europe, US | Inspire therapy, ADHERE, No intervention, CONTROL | Inspire Medical Systems, Inc. | Obstructive Sleep Apnea | 09/25 | 12/25 | | |
| Abosch, Aviva |
NCT04620551: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease |
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| Active, not recruiting | N/A | 20 | US | Sub-clinical stimulation | University of Nebraska, Stanford University, University of Colorado, Denver, University of Pennsylvania | Parkinson Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
NCT04799470: Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease |
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| Recruiting | N/A | 10 | US | Novel DBS stimulation patterns | University of Nebraska | Parkinson's Disease | 03/25 | 03/25 | | |
NCT03622905: ADvance II Study: DBS-f in Patients With Mild Alzheimer's Disease |
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| Completed | N/A | 74 | Europe, Canada, US | DBS-f On, DBS Off | Functional Neuromodulation Ltd | Alzheimer Disease | 02/24 | 02/24 | | |
NCT05070013: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2) |
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| Recruiting | N/A | 20 | US | Deep Brain Stimulation | University of Nebraska | Parkinson's Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
| Halpern, Casey |
NCT04620551: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease |
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| Active, not recruiting | N/A | 20 | US | Sub-clinical stimulation | University of Nebraska, Stanford University, University of Colorado, Denver, University of Pennsylvania | Parkinson Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
| Recruiting | N/A | 100 | US | Sham-stimulation, Active-stimulation | Abbott Medical Devices | Treatment Resistant Depression | 04/27 | 04/29 | | |
| Recruiting | N/A | 6 | US | responsive neurostimulation | University of Pennsylvania, NeuroPace | Loss of Control Eating, Obesity, Morbid | 01/25 | 01/25 | | |
NCT05070013: Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2) |
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| Recruiting | N/A | 20 | US | Deep Brain Stimulation | University of Nebraska | Parkinson's Disease, Sleep Fragmentation | 06/25 | 06/25 | | |
NCT05539196: A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications |
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| Recruiting | N/A | 60 | Japan, US | Exablate Pallidotomy, Unilateral | InSightec | Movement Disorders, Neurology, Parkinsons Disease | 07/29 | 07/29 | | |
