University of Pennsylvania, Scheie Eye Institute
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 2 Trials 
9 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Tamhankar, Madhura
UplighTED, NCT06307613: A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults with Thyroid Eye Disease

Recruiting
3
108
Europe, US, RoW
Efgartigimod PH20 SC, Placebo PH20 SC
argenx
Thyroid Eye Disease
02/26
10/27
THRIVE, NCT05176639 / 2021-006794-37: A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants with Thyroid Eye Disease (TED) ( )

Active, not recruiting
3
154
Europe, Canada, US, RoW
Veligrotug (VRDN-001) Phase 1/2 MAD (HV and TED), VRDN-001 Phase 3 Cohort (THRIVE), VRDN-001 Placebo
Viridian Therapeutics, Inc., Viridian Therapeutics, Inc.
Thyroid Eye Disease
07/24
03/25
Dupont, Joan
NCT05705024: Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

Recruiting
2
38
US
Mesenchymal Stromal Cells, Control Solution
University of Illinois at Chicago, United States Department of Defense
Corneal Ulcer
09/25
09/25
Aleman, Tomas
NAC Attack, NCT05537220: Oral N-acetylcysteine for Retinitis Pigmentosa

Recruiting
3
438
Europe, Canada, US, RoW
N-acetylcysteine, Placebo
Johns Hopkins University, National Eye Institute (NEI), Duke University, Emory University, Massachusetts Eye and Ear Infirmary, Mayo Clinic, Medical College of Wisconsin, Retina Foundation of the Southwest, Stanford University, University of California, Davis, University of Florida, University of Iowa, University of Miami, University of Michigan, University of Minnesota, University of Oklahoma, University of Southern California, University of Utah, University of Washington, University of Wisconsin, Madison, Vanderbilt University, Vitreo Retinal Associates, PA, University of Houston, Medical University of Graz, McGill University, Universität Tübingen, Centro Medico ABC, Radboud University Medical Center, University of Amsterdam, University Hospital, Basel, Switzerland, University College London Hospitals, Northwestern University, University of Pennsylvania
Retinitis Pigmentosa
12/28
12/28
NCT05616793: Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD)

Recruiting
1/2
15
US
AAV8.hLCA5
Opus Genetics, Inc, University of Pennsylvania
LCA5
12/24
01/28
LIGHTHOUSE, NCT05878860: ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

Recruiting
1/2
21
US
ATSN-201
Atsena Therapeutics Inc.
X-linked Retinoschisis
10/25
10/29
Uni-Rare, NCT05589714: Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

Recruiting
N/A
1500
Europe, Canada, US, RoW
Jaeb Center for Health Research, Foundation Fighting Blindness
Inherited Retinal Degeneration, Retinitis Pigmentosa
12/28
12/28
Utz, Megan
NCT05705024: Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

Recruiting
2
38
US
Mesenchymal Stromal Cells, Control Solution
University of Illinois at Chicago, United States Department of Defense
Corneal Ulcer
09/25
09/25
NCT04626583: Safety of Locally Delivered Allogeneic Mesenchymal Stromal Cells

Completed
1
8
US
Allogeneic MSC
University of Illinois at Chicago, United States Department of Defense
Mesenchymal Stromal Cells, Cornea, Safety, Corneal Defect
04/23
04/23

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